The enzyme that adds poly(A) to mRNAs is a classical poly(A) polymerase.

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

A Polynucleotide Segment Rich in Adenylic Acid in the Rapidly-Labeled Polyribosomal RNA Component of Mouse Sarcoma 180 Ascites Cells

1971 • 521 citations

Polyadenylic Acid Sequences in the Heterogeneous Nuclear RNA and Rapidly-Labeled Polyribosomal RNA of HeLa Cells: Possible Evidence for a Precursor Relationship

1971 • 503 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

An Adenylic Acid-Rich Sequence in Messenger RNA of HeLa Cells and Its Possible Relationship to Reiterated Sites in DNA

1971 • 389 citations

Polynucleotide Biosynthesis: Formation of a Sequence of Adenylate Units from Adenosine Triphosphate by an Enzyme from Thymus Nuclei

1960 • 231 citations

3′ cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP

1988 • 205 citations

Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation

1988 • 195 citations

The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro.

1986 • 147 citations

Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro.

1989 • 104 citations

Two phases in the addition of a poly(A) tail.

1989 • 98 citations

A Poly(A) Polymerase from Calf Thymus

1973 • 96 citations

RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro.

1985 • 95 citations

Analysis of RNA cleavage at the adenovirus-2 L3 polyadenylation site.

1986 • 94 citations

Purification of terminal riboadenylate transferase from calf thymus gland.

1975 • 89 citations

Formation of mRNA 3′ termini: stability and dissociation of a complex involving the AAUAAA sequence.

1987 • 83 citations

Multiple factors are required for poly(A) addition to a mRNA 3' end.

1988 • 65 citations

Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs.

1987 • 64 citations

A Poly(A) Polymerase from Calf Thymus

1973 • 61 citations

8 Poly(A) Adding Enzymes

1982 • 48 citations

Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor.

1989 • 36 citations

Polyadenylation-specific complexes undergo a transition early in the polymerization of a poly(A) tail.

1990 • 12 citations