Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3'-end formation.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

Polyadenylation of mRNA precursors

1988 • 210 citations

3′ cleavage and polyadenylation of mRNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a snRNP

1988 • 205 citations

Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation

1988 • 195 citations

The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro.

1986 • 147 citations

Multiple factors are required for specific RNA cleavage at a poly(A) addition site.

1988 • 106 citations

Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro.

1989 • 104 citations

A Poly(A) Polymerase from Calf Thymus

1973 • 96 citations

Analysis of RNA cleavage at the adenovirus-2 L3 polyadenylation site.

1986 • 94 citations

Accurate and specific polyadenylation of mRNA precursors in a soluble whole-cell lysate

1983 • 94 citations

Metabolism of the polyadenylate sequence of nuclear RNA and messenger RNA in mammalian cells

1975 • 91 citations

Purification of terminal riboadenylate transferase from calf thymus gland.

1975 • 89 citations

Elongation of the Polyadenylate Segment of Messenger RNA in the Cytoplasm of Mammalian Cells

1974 • 69 citations

The AAUAAA Sequence Is Required both for Cleavage and for Polyadenylation of Simian Virus 40 Pre-mRNA In Vitro

1986 • 69 citations

Isolation and partial characterization of the poly(A) polymerases from HeLa cells infected with vaccinia virus.

1977 • 66 citations

Multiple factors are required for poly(A) addition to a mRNA 3' end.

1988 • 65 citations

Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs.

1987 • 64 citations

Phosphorylation of nuclear poly(A) polymerase. Comparison of liver and hepatoma enzymes.

1979 • 61 citations

Sequences Downstream of AAUAAA Signals Affect Pre-mRNA Cleavage and Polyadenylation In Vitro Both Directly and Indirectly

1989 • 61 citations

Requirements for accurate and efficient mRNA 3' end cleavage and polyadenylation of a simian virus 40 early pre-RNA in vitro.

1987 • 56 citations

8 Poly(A) Adding Enzymes

1982 • 48 citations

Role of poly(A) polymerase in the cleavage and polyadenylation of mRNA precursor.

1989 • 36 citations

Products of In Vitro Cleavage and Polyadenylation of Simian Virus 40 Late Pre-mRNAs

1987 • 35 citations

Three Distinct Forms of Nuclear Poly(A) Polymerase

1975 • 33 citations

Requirements for Accurate and Efficient mRNA 3′ end Cleavage and Polyadenylation of a Simian Virus 40 early pre-RNA In Vitro

1987 • 30 citations

Evidence for the existence of two different poly(A) polymerases and a novel ribohomopolymer polymerase in rat liver nuclei

1974 • 25 citations

Structurally and immunologically distinct poly(A) polymerases in rat liver. Occurrence of a tumor-type enzyme in normal liver.

1984 • 25 citations

Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly.

1989 • 23 citations

Polyadénylate synthétase des cellules d'ascite de souris

1972 • 17 citations

Comparison of cytosolic and nuclear poly(A) polymerases from rat liver and a hepatoma: structural and immunological properties and response to NI-type protein kinases

1985 • 17 citations

Role of Poly(A) Polymerase in the Cleavage and Polyadenylation of mRNA Precursor

1989 • 15 citations

Characterization of two poly(A) polymerases from cultured hamster fibroblasts

1978 • 13 citations