Products of in vitro cleavage and polyadenylation of simian virus 40 late pre-mRNAs.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

Mapping adenines, guanines, and pyrimidines in RNA

1977 • 1,391 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Variety in the level of gene control in eukaryotic cells

1982 • 772 citations

Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro

1984 • 761 citations

Normal and mutant human β-globin pre-mRNAs are faithfully and efficiently spliced in vitro

1984 • 679 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Recognition of cap structure in splicing in vitro of mRNA precursors

1984 • 575 citations

Polyadenylic Acid Sequences: Role in Conversion of Nuclear RNA into Messenger RNA

1971 • 569 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1984 • 561 citations

Biological Catalysis by RNA

1986 • 496 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors

1984 • 474 citations

Minor Components in Transfer RNA: Their Characterization, Location, and Function

1972 • 411 citations

Small RNA species of the HeLa cell: Metabolism and subcellular localization

1976 • 409 citations

α-Thalassaemia caused by a polyadenylation signal mutation

1983 • 407 citations

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

1984 • 379 citations

Characteristics of the polyadenylic acid segment associated with messenger ribonucleic acid in mouse sarcoma 180 ascites cells

1972 • 339 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

Determination of Sequences in RNA

1972 • 314 citations

Inhibition of RNA cleavage but not polyadenylation by a point mutation in mRNA 3′ consensus sequence AAUAAA

1983 • 278 citations

Messenger RNA splicing in vitro: An excised intervening sequence and a potential intermediate

1984 • 262 citations

Requirement of a downstream sequence for generation of a poly(A) addition site

1984 • 261 citations

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

1984 • 251 citations

Transcription and RNA processing by the DNA tumour viruses

1980 • 228 citations

Site-specific polyadenylation in a cell-free reaction

1984 • 223 citations

Sequence-specific adenylations and deadenylations accompany changes in the translation of maternal messenger RNA after fertilization of Spisula oocytes

1983 • 190 citations

Splicing of yeast tRNA precursors: structure of the reaction intermediates

1979 • 173 citations

Formation of a 2′-phosphomonoester, 3′,5′-phosphodiester linkage by a novel RNA ligase in wheat germ

1981 • 154 citations

Generation of histone mRNA 3′ ends by endonucleolytic cleavage of the pre-mRNA in a snRNP-dependent in vitro reaction.

1986 • 151 citations

The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro.

1986 • 147 citations

A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.

1985 • 139 citations

A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitro

1986 • 139 citations

Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly.

1984 • 114 citations

The RNA lariat: A new ring to the splicing of mRNA precursors

1984 • 113 citations

Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site.

1984 • 113 citations

Requirement for the 3' flanking region of the bovine growth hormone gene for accurate polyadenylylation.

1984 • 109 citations

RNA ligation via 2'-phosphomonoester, 3'5'-phosphodiester linkage: requirement of 2',3'-cyclic phosphate termini and involvement of a 5'-hydroxyl polynucleotide kinase.

1982 • 109 citations

Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing.

1985 • 105 citations

Analysis of RNA cleavage at the adenovirus-2 L3 polyadenylation site.

1986 • 94 citations

Behavior of indivdual maternal pA+ RNAs during embryogenesis of Xenopus laevis

1982 • 88 citations

Specific inhibition of chromatin-associated poly(A) synthesis in vitro by cordycepin 5′-triphosphate

1977 • 73 citations

Apparent involvement of ribonuclease D in the 3' processing of tRNA precursors.

1980 • 71 citations

Formation of low molecular weight RNA species in HeLa cells

1980 • 64 citations

Effects of cordycepin and cordycepintriphosphate on polyadenylic and ribonucleic acid-synthesising enzymes from eukaryotes

1975 • 50 citations

Mode of inhibition of nuclear poly(A)polymerase by 2'‐dATP and 3'‐dATP

1978 • 8 citations