Molecular Mechanisms and Clinical Implications of Reversible ProteinS-Glutathionylation

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Protein Sulfenic Acids in Redox Signaling

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Oxidative Stress and Hypertension

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Activation of Matrix Metalloproteinases by Peroxynitrite-induced Protein S-Glutathiolation via Disulfide S-Oxide Formation

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Dynamic redox control of NF-κB through glutaredoxin-regulated S-glutathionylation of inhibitory κB kinase β

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The Biochemistry and Physiology of S-Nitrosothiols

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Modular Activation of Nuclear Factor-κB Transcriptional Programs in Human Diabetic Nephropathy

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Glutaredoxin 2 Catalyzes the Reversible Oxidation and Glutathionylation of Mitochondrial Membrane Thiol Proteins

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Reversible Glutathionylation of Complex I Increases Mitochondrial Superoxide Formation

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Glutathionylation of the p50 Subunit of NF-κB: a Mechanism for Redox-Induced Inhibition of DNA Binding

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Activation of Nuclear Factor-κB Induced by Diabetes and High Glucose Regulates a Proapoptotic Program in Retinal Pericytes

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Reversible Glutathionylation Regulates Actin Polymerization in A431 Cells

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Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with πGST

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Redox regulation of c‐Jun DNA binding by reversible S‐glutathiolation

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Molecular Mechanisms and Potential Clinical Significance ofS-Glutathionylation

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Role of Glutaredoxin in Metabolic Oxidative Stress

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Involvement of Oxidative Stress in the Pathogenesis of Diabetes

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PTP1B inhibitors as potential therapeutics in the treatment of Type 2 diabetes and obesity

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Identification and Characterization of a New Mammalian Glutaredoxin (Thioltransferase), Grx2

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Mitochondrial Complex II in the Post-ischemic Heart

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Characterization of Sulfur-centered Radical Intermediates Formed during the Oxidation of Thiols and Sulfite by Peroxynitrite

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Ischemic Preconditioning Reduces Apoptosis By Upregulating Anti-Death Gene Bcl-2

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Redox regulation of ubiquitin‐conjugating enzymes: mechanistic insights using the thiol‐specific oxidant diamide

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Identification of Oxidant-Sensitive Proteins: TNF-α Induces Protein Glutathiolation

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Importance of oxidative stress in the pathogenesis and treatment of asthma

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S-Glutathionylation: Indicator of Cell Stress and Regulator of the Unfolded Protein Response

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Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro

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Nucleoredoxin, Glutaredoxin, and Thioredoxin Differentially Regulate NF-κB, AP-1, and CREB Activation in HEK293 Cells

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Mitochondrial dysfunction, oxidative stress and neurodegeneration

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Biothiols in Health and Disease

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Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain

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Reversible S-glutathionylation of Cys374 regulates actin filament formation by inducing structural changes in the actin molecule

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Human p53 Is Inhibited by Glutathionylation of Cysteines Present in the Proximal DNA-Binding Domain during Oxidative Stress^,

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Sulfhydryl oxidases: emerging catalysts of protein disulfide bond formation in eukaryotes

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Caspase Activation in Retinas of Diabetic and Galactosemic Mice and Diabetic Patients

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Oxidation and Nitrosation of Thiols at Low Micromolar Exposure to Nitric Oxide

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Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2

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Glutathionylation of Mitochondrial Proteins

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Induction of Phase I and Phase II Drug-Metabolizing Enzyme mRNA, Protein, and Activity by BHA, Ethoxyquin, and Oltipraz

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A Novel Role for Human Sulfiredoxin in the Reversal of Glutathionylation

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S-Glutathiolated Hepatocyte Proteins and Insulin Disulfides as Substrates for Reduction by Glutaredoxin, Thioredoxin, Protein Disulfide Isomerase, and Glutathione

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The Active Site Cysteine of the Proapoptotic Protein Glyceraldehyde-3-phosphate Dehydrogenase Is Essential in Oxidative Stress-induced Aggregation and Cell Death

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Glutathione-Thiyl Radical Scavenging and Transferase Properties of Human Glutaredoxin (Thioltransferase)

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Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1

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Catalytic and Chemical Competence of Regulation of Cdc25 Phosphatase by Oxidation/Reduction

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Mitochondrial Dysfunction in Aging and Alzheimer's Disease: Strategies to Protect Neurons

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Regulation of cAMP-dependent Protein Kinase Activity by Glutathionylation

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The Redox Regulation of Thiol Dependent Signaling Pathways in Cancer

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Akt in Ischemia and Reperfusion

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S-Nitrosylation and S-Glutathiolation of Protein Sulfhydryls byS-Nitroso Glutathione

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Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP

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Glutathione in blood of patients with Friedreich's ataxia

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Involvement of glutaredoxin-1 and thioredoxin-1 in β-amyloid toxicity and Alzheimer's disease

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An increase in S‐glutathionylated proteins in the Alzheimer's disease inferior parietal lobule, a proteomics approach

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Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines

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Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation

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Thioltransferase (Glutaredoxin) Is Detected Within HIV-1 and Can Regulate the Activity of Glutathionylated HIV-1 Protease in Vitro

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Effects of Diabetes on Ryanodine Receptor Ca Release Channel (RyR2) and Ca2+ Homeostasis in Rat Heart

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Glutathiolation Regulates Tumor Necrosis Factor-α–Induced Caspase-3 Cleavage and Apoptosis

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Thioltransferase (Glutaredoxin) Reactivates the DNA-binding Activity of Oxidation-inactivated Nuclear Factor I

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Glycogen Phosphorylase as a Molecular Target for Type 2 Diabetes Therapy

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Reversible Inactivation of α-Ketoglutarate Dehydrogenase in Response to Alterations in the Mitochondrial Glutathione Status

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Glutathione Supplementation Potentiates Hypoxic Apoptosis by S-Glutathionylation of p65-NFκB

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Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release

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Oxidants and Signaling by Mitogen-Activated Protein Kinases in Lung Epithelium

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The mitochondrial permeability transition in neurologic disease

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Actin Glutathionylation Increases in Fibroblasts of Patients with Friedreich's Ataxia

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Nitric Oxide Inhibits c-Jun DNA Binding by Specifically TargetedS-Glutathionylation

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Reactivity of the Human Thioltransferase (Glutaredoxin) C7S, C25S, C78S, C82S Mutant and NMR Solution Structure of Its Glutathionyl Mixed Disulfide Intermediate Reflect Catalytic Specificity^,

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Metabolic, Metallic, and Mitotic Sources of Oxidative Stress in Alzheimer Disease

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Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

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1-Methyl-4-Phenylpyridinium Induces Autocrine Excitotoxicity, Protease Activation, and Neuronal Apoptosis

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Kinetics and equilibria of S‐nitrosothiol—thiol exchange between glutathione, cysteine, penicillamines and serum albumin

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Reactive Nitrogen Species Induced by Hyperglycemia Suppresses Akt Signaling and Triggers Apoptosis by Upregulating Phosphatase PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) in an LKB1-Dependent Manner

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The phosphatase activity of carbonic anhydrase III is reversibly regulated by glutathiolation.

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Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide

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Stable and controllable RNA interference: Investigating the physiological function of glutathionylated actin

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NF-κB as an Integrator of Diverse Signaling Pathways: The Heart of Myocardial Signaling?

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Reversible Sequestration of Active Site Cysteines in a 2Fe-2S-bridged Dimer Provides a Mechanism for Glutaredoxin 2 Regulation in Human Mitochondria

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Caspase-3-Dependent β-Cell Apoptosis in the Initiation of Autoimmune Diabetes Mellitus

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Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and β-amyloid pathologies

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Protein-Tyrosine Phosphatase 1B (PTP1B): A Novel Therapeutic Target for Type 2 Diabetes Mellitus, Obesity and Related States of Insulin Resistance

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Reduction of glyceraldehyde‐3‐phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts

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pH Profiles Indicative of Rate-Limiting Nucleophilic Displacement in Thioltransferase Catalysis

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Regulation of Mitochondrial NADP+-dependent Isocitrate Dehydrogenase Activity by Glutathionylation

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Critical role of ASK1 in the 6‐hydroxydopamine‐induced apoptosis in human neuroblastoma SH‐SY5Y cells

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Activation of apoptosis signal regulating kinase 1 (ASK1) and translocation of death‐associated protein, Daxx, in substantia nigra pars compacta in a mouse model of Parkinson's disease: protection by α‐lipoic acid

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Oxidant-Induced S-Glutathiolation Inactivates Protein Kinase C-α (PKC-α): A Potential Mechanism of PKC Isozyme Regulation

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Expression of Glutaredoxin in Human Coronary Arteries

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Cellular and Molecular Abnormalities in the Vascular Endothelium of Diabetes Mellitus

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Tachycardia increases NADPH oxidase activity and RyR2 S-glutathionylation in ventricular muscle

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The Glutathione Peroxidase Reaction: Molecular Basis of the Antioxidant Function of Selenium in Mammals

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20 S Proteasome from Saccharomyces cerevisiae Is Responsive to Redox Modifications and IsS-Glutathionylated

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S‐glutathiolation by peroxynitrite of p21ras at cysteine‐118 mediates its direct activation and downstream signaling in endothelial cells

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Reversible Inhibition of α-Ketoglutarate Dehydrogenase by Hydrogen Peroxide: Glutathionylation and Protection of Lipoic Acid

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Thioltransferase in human red blood cells: purification and properties

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S-Nitrosation versus S-Glutathionylation of Protein Sulfhydryl Groups by S-Nitrosoglutathione

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Inhibition of Cathepsin K by Nitric Oxide Donors: Evidence for the Formation of Mixed Disulfides and a Sulfenic Acid

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S-Glutathionylation Decreases Mg2+ Inhibition and S-Nitrosylation Enhances Ca2+ Activation of RyR1 Channels

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Pathobiology of Atherosclerosis-a Brief Review

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Broccoli: A Unique Vegetable That Protects Mammalian Hearts through the Redox Cycling of the Thioredoxin Superfamily

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What effects might anti-TNF treatment be expected to have on cardiovascular morbidity and mortality in rheumatoid arthritis? A review of the role of TNF in cardiovascular pathophysiology

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Glyceraldehyde Phosphate Dehydrogenase Oxidation During Cardiac Ischemia and Reperfusion

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Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria‐mediated apoptosis

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Inactivation of creatine kinase by S-glutathionylation of the active-site cysteine residue

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Studies on the Mechanism of Oxidative Modification of Human Glyceraldehyde-3-phosphate Dehydrogenase by Glutathione: Catalysis by Glutaredoxin

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Kinetic and Mechanistic Characterization and Versatile Catalytic Properties of Mammalian Glutaredoxin 2: Implications for Intracellular Roles

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Nitrosylation: the next phosphorylation?

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Protein glutathiolation by nitric oxide: an intracellular mechanism regulating redox protein modification

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Glutaredoxin Regulates Nuclear Factor κ-B and Intercellular Adhesion Molecule in Müller Cells

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Ischemia–reperfusion injury in the aged heart: role of mitochondria

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Oxidative stress and hypertension

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Actin S-glutathionylation: evidence against a thiol-disulphide exchange mechanism

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Glucose-induced mixed [Ca²⁺]_c oscillations in mouse β-cells are controlled by the membrane potential and the SERCA3 Ca²⁺-ATPase of the endoplasmic reticulum

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Transcriptional regulation via cysteine thiol modification: A novel molecular strategy for chemoprevention and cytoprotection

2006 • 111 citations

Glutathione S‐Transferases as Regulators of Kinase Pathways and Anticancer Drug Targets

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17β-Estradiol Protects against Oxidative Stress-induced Cell Death through the Glutathione/Glutaredoxin-dependent Redox Regulation of Akt in Myocardiac H9c2 Cells

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Reaction of S-nitrosoglutathione with sulfhydryl groups in protein

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Direct oxidative modifications of signalling proteins in mammalian cells and their effects on apoptosis

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Redox in redux: Emergent roles for glutathione S-transferase P (GSTP) in regulation of cell signaling and S-glutathionylation

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Insights into Deglutathionylation Reactions

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Glutathionylation of proteins by glutathione disulfide S-oxide

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Protein Kinase A as Another Mediator of Ischemic Preconditioning Independent of Protein Kinase C

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Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease?

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GLUTATHIONE-HOMOCYSTINE TRANSHYDROGENASE

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A Glutathione S-Transferase π-Activated Prodrug Causes Kinase Activation Concurrent with S-Glutathionylation of Proteins

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Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells

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Oxidation and S-Nitrosylation of Cysteines in Human Cytosolic and Mitochondrial Glutaredoxins

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Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection

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Dopamine Biosynthesis Is Regulated byS-Glutathionylation

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Regulation of HIV-1 Protease Activity through Cysteine Modification

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Phosphoinositide 3-kinase signaling in the cellular response to oxidative stress

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Functional nonequality of the cardiac and skeletal ryanodine receptors

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How Does Iron–Sulfur Cluster Coordination Regulate the Activity of Human Glutaredoxin 2?

2006 • 99 citations

Expression of Calbindin-D_28kin a Pancreatic Isletβ -Cell Line Protects against Cytokine-Induced Apoptosis and Necrosis

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Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia

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Antioxidants in cystic fibrosis☆Conclusions from the CF Antioxidant Workshop, Bethesda, Maryland, November 11-12, 2003

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N-Acetyl-l-cysteine Enhances Apoptosis through Inhibition of Nuclear Factor-κB in Hypoxic Murine Embryonic Fibroblasts

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Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance

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Properties of a flavoprotein sulfhydryl oxidase from rat seminal vesicle secretion

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Expression Pattern of Human Glutaredoxin 2 Isoforms: Identification and Characterization of Two Testis/Cancer Cell-Specific Isoforms

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SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca2+ Pumps for Ca2+ Homeostasis in Pancreatic β-cells

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Multidomain Flavin-Dependent Sulfhydryl Oxidases

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Strain-stimulated hypertrophy in cardiac myocytes is mediated by reactive oxygen species-dependent Ras S-glutathiolation

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What is the Functional Significance of the Unique Location of Glutaredoxin 1 (GRx1) in the Intermembrane Space of Mitochondria?

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Ryanodine receptors in human pancreatic β cells: localization and effects on insulin secretion

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Possible Differences in the Regenerative Roles Played by Thioltransferase and Thioredoxin for Oxidatively Damaged Proteins

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Antioxidant therapies in COPD

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In vivo thiyl free radical formation from hemoglobin following administration of hydroperoxides

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Thiotransferase in human red blood cells: kinetics and equilibrium

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Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism

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Decline of contractility during ischemia-reperfusion injury: actin glutathionylation and its effect on allosteric interaction with tropomyosin

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Enhanced protein glutathiolation and oxidative stress in cigarette smokers

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Glutaredoxin is essential for maintenance of brain mitochondrial complex I: studies with MPTP

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Protein S-Glutathiolation Triggered by DecomposedS-Nitrosoglutathione

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Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats

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Conditional disruption of IκB kinase 2 fails to prevent obesity-induced insulin resistance

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PKC inhibition and diabetic microvascular complications

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Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-β in vitro and in interstitial lung diseases in vivo

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High glucose oxidizes SERCA cysteine-674 and prevents inhibition by nitric oxide of smooth muscle cell migration

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Glutathiolation of Proteins by Glutathione DisulfideS-Oxide Derived from S-Nitrosoglutathione

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ATP-sensitive potassium channels in adult mouse skeletal muscle: Characterization of the ATP-binding site

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S-Glutathiolation of p21ras by Peroxynitrite Mediates Endothelial Insulin Resistance Caused by Oxidized Low-Density Lipoprotein

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Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary disease

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Increased glutathionylated hemoglobin (HbSSG) in type 2 diabetes subjects with microangiopathy

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Computational and Mutational Analysis of Human Glutaredoxin (Thioltransferase): Probing the Molecular Basis of the Low pK_a of Cysteine 22 and Its Role in Catalysis^,,

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17beta-estradiol induces protein thiol/disulfide oxidoreductases and protects cultured bovine aortic endothelial cells from oxidative stress

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Effects of oxidative and nitrosative stress in brain on p53 proapoptotic protein in amnestic mild cognitive impairment and Alzheimer disease

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Glutaredoxin Modulates Platelet-derived Growth Factor-dependent Cell Signaling by Regulating the Redox Status of Low Molecular Weight Protein-tyrosine Phosphatase

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Mechanism of action of enzymes catalyzing thiol—disulfide interchange. Thioltransferases rather than transhydrogenases

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Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells

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Potent inactivation of representative members of each PKC isozyme subfamily and PKD via S-thiolation by the tumor-promotion/progression antagonist glutathione but not by its precursor cysteine

2001 • 66 citations

S-glutathionylation of IRF3 regulates IRF3–CBP interaction and activation of the IFNβ pathway

2008 • 66 citations

Molecular mechanism of glutathione-mediated protection from oxidized low-density lipoprotein-induced cell injury in human macrophages: Role of glutathione reductase and glutaredoxin

2006 • 66 citations

Detection of redox-based modification in two-dimensional electrophoresis proteomic separations

2006 • 65 citations

Unlocking the Mdm2-p53 loop: Ubiquitin is the key

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Activation of the Ras/mitogen-activated protein kinase signaling pathway alone is not sufficient to induce glucose uptake in 3T3-L1 adipocytes.

1994 • 64 citations

PKC isozyme S-cysteinylation by cystine stimulates the pro-apoptotic isozyme PKCdelta and inactivates the oncogenic isozyme PKCvarepsilon

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Overexpression and nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase in a transgenic mouse model of Huntington’s disease

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Protein S-Thiolation and Regulation of Microsomal Glutathione Transferase Activity by the Glutathione Redox Couple

1996 • 63 citations

Glucose and Endoplasmic Reticulum Calcium Channels Regulate HIF-1β via Presenilin in Pancreatic β-Cells

2008 • 63 citations

Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease?

2002 • 62 citations

Inhibition of Protein Tyrosine Phosphatase 1B as a Potential Treatment of Diabetes and Obesity

2004 • 62 citations

RETRACTED: Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis

2007 • 61 citations

Novel functions of the α-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease

2008 • 60 citations

Mitochondrial thioltransferase (glutaredoxin 2) has GSH‐dependent and thioredoxin reductase‐dependent peroxidase activitiesin vitroand in lens epithelial cells

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Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase

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Tachycardia Preconditions Infarct Size in Dogs

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SAG/ROC2 E3 ligase regulates skin carcinogenesis by stage-dependent targeting of c-Jun/AP1 and IκB-α/NF-κB

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Diabetes Induced in Male Transgenic Mice by Expression of Human H-ras Oncoprotein in Pancreatic β Cells

1990 • 55 citations

Induction of thioredoxin, thioredoxin reductase and glutaredoxin activity in mouse skin by TPA, a calcium ionophore and other tumor promoters

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Redox regulation of I_to remodeling in diabetic rat heart

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Insulin Deficiency Downregulated Heat Shock Protein 60 and IGF-1 Receptor Signaling in Diabetic Myocardium

2005 • 54 citations

A Method for Measuring Disulfide Reduction by Cultured Mammalian Cells: Relative Contributions of Glutathione-Dependent and Glutathione-Independent Mechanisms

2000 • 54 citations

Chemopreventive promise of targeting the Nrf2 pathway

2007 • 51 citations

Constitutive expression and functional characterization of mitochondrial glutaredoxin (Grx2) in mouse and human brain

2007 • 50 citations

PKC/Raf/MEK/ERK signaling pathway modulates native-LDL-induced E2F-1 gene expression and endothelial cell proliferation

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1995 • 48 citations

Effects of thiol-modifying agents on KATP channels in guinea pig ventricular cells

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Interleukin-1β Stimulation of c-Jun NH2-Terminal Kinase Activity in Insulin-Secreting Cells

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Glutaredoxin Mediates Akt and eNOS Activation by Flow in a Glutathione Reductase-Dependent Manner

2007 • 47 citations

Ryanodine Receptor Dysfunction in Hearts of Streptozotocin-Induced Diabetic Rats

2001 • 47 citations

[7] Reaction of superoxide with glutathioneand other thiols

1995 • 47 citations

Cellular and Molecular Targets of ProteinS-Glutathiolation

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Proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase: a possible site of action of antiapoptotic drugs

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Ascorbic acid and cell survival of adriamycin resistant and sensitive MCF-7 breast tumor cells

1995 • 46 citations

Thioredoxin Regulation of Ischemic Preconditioning

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Involvement of Glyceraldehyde-3-Phosphate Dehydrogenase in Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Death of Thyroid Cancer Cells

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UVB radiation-activated genes induced by transcriptional and posttranscriptional mechanisms in rat keratinocytes

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Modification of Aldose Reductase by S-Nitrosoglutathione

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Immunochemical characterization and tissue distribution of glutaredoxin (thioltransferase) from calf.

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Thioltransferase (Glutaredoxin) Mediates Recovery of Motor Neurons from Excitotoxic Mitochondrial Injury

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Endogenous intracellular glutathionyl radicals are generated in neuroblastoma cells under hydrogen peroxide oxidative stress.

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Control of p53 nuclear accumulation in stressed cells

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Downregulation of glutaredoxin but not glutathione loss leads to mitochondrial dysfunction in female mice CNS: Implications in excitotoxicity

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Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification

1998 • 37 citations

RETRACTED: Role of glutaredoxin-1 in cardioprotection: An insight with Glrx1 transgenic and knockout animals

2007 • 36 citations

Serum Levels of S-Glutathionylated Proteins as a Risk-Marker for Arteriosclerosis Obliterans

2006 • 36 citations

Immunohistochemical localization of glutaredoxin and thioredoxin in human endometrium: a possible association with pinopodes

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Glutathione, glutathione utilizing enzymes and thioltransferase in platelets of insulin‐dependent diabetic patients: relation with platelet aggregation and with microangiopatic complications

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Renal Microvascular Injury in Diabetes: RAGE and Redox Signaling

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Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells.

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The human glutaredoxin gene: determination of its organization, transcription start point, and promoter analysis

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Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis

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Role of the Golgi Apparatus in the Phosphorylation of Apolipoprotein B

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Increased oxidative stress in diabetes regulates activation of a small molecular weight G-protein, H-Ras, in the retina.

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Redox regulation of the proteasome in T lymphocytes during aging

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Haloperidol induces the nuclear translocation of phosphatidylinositol 3'-kinase to disrupt Akt phosphorylation in PC12 cells.

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Serum adipocyte fatty acid binding protein levels in patients with type 2 diabetes mellitus and obesity: the influence of fenofibrate treatment

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Adenovirus-Mediated Gene Transfer of Dominant Negative Ras^asn17in 3T3L1 Adipocytes Does Not Alter Insulin-Stimulated PI3-Kinase Activity or Glucose Transport

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Angiotensin II protects against α-synuclein toxicity and reduces protein aggregation in vitro

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UPDATE OF DIAGNOSTIC AND PROGNOSTIC MARKERS IN CUTANEOUS MALIGNANT MELANOMA

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Purification of Proteins Susceptible to Oxidation at Cysteine Residues: Identification of Malate Dehydrogenase as a Target for S‐Glutathiolation

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Application of High-Density DNA Microarray to Study Smoke- and Hydrogen Peroxide–Induced Injury and Repair in Human Bronchial Epithelial Cells

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Structural insights into Alzheimer filament assembly pathways based on site‐directed mutagenesis and S‐glutathionylation of three‐repeat neuronal Tau protein

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DNA repair Ku proteins in gastric cancer cells and pancreatic acinar cells

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Functional glutaredoxin (thioltransferase) activity in rat brain and liver mitochondria

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The expression of glutaredoxin is increased in the human cervix in term pregnancy and immediately post-partum, particularly after prostaglandin-induced delivery

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Effects of p53 inhibitor on survival and death of cells subjected to oxidative stress.

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Mutation in G6PD gene leads to loss of cellular control of protein glutathionylation: Mechanism and implication

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Effects of chemical modification of amino and sulfhydryl groups on KATP channel function and sulfonylurea binding in CRI-G1 insulin-secreting cells

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The multiple roles of p53 in the pathogenesis of HIV associated dementia

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The Effect of Experimental Diabetes on Liver Alcohol Dehydrogenase Activity in Rats

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Disulfide-Cross-Linked Tau and MAP2 Homodimers Readily Promote Microtubule Assembly

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Decrease in malate dehydrogenase activities in peripheral leucocytes of type 1 diabetic dogs

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Immunohistochemical determination of thioredoxin and glutaredoxin distribution in the human cervix ,and possible relation to cervical ripening

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Renal activity of Akt kinase in experimental Type 1 diabetes

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Role of the ubiquitin-proteasome system in carotid plaque instability in diabetic patients

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Views on neurodegeneration as a basis for neuroprotective strategies.

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Molecular Targeted Agents in Non–Small-Cell Lung Cancer

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SERCA in genesis of arrhythmias: what we already know and what is new?

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NEM modification prevents high‐affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1

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Insulin responsiveness of CK-M and CK-B mRNA in the diabetic rat heart

1991 • 11 citations

Expression of Calbindin-D28k in a Pancreatic Islet -Cell Line Protects against Cytokine-Induced Apoptosis and Necrosis

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Immunohistochemical determination of thioredoxin and glutaredoxin distribution in the human cervix, and possible relation to cervical ripening

2003 • 10 citations

Adenovirus-Mediated Gene Transfer of Dominant Negative Rasasn17 in 3T3L1 Adipocytes Does Not Alter Insulin-Stimulated PI3-Kinase Activity or Glucose Transport

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The oxidation of cyst(e)ine by mast-cell tumour P815 in culture

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