Inactivation of creatine kinase by S-glutathionylation of the active-site cysteine residue

The Glutathione Status of Cells

1978 • 1,218 citations

Reversible Inactivation of Protein-tyrosine Phosphatase 1B in A431 Cells Stimulated with Epidermal Growth Factor

1998 • 968 citations

[2] Thiol/disulfide exchange equilibria and disulfidebond stability

1995 • 535 citations

Regulation of PTP1B via Glutathionylation of the Active Site Cysteine 215

1999 • 492 citations

Analysis of biological thiols: Derivatization with monobromobimane and separation by reverse-phase high-performance liquid chromatography

1981 • 451 citations

Protein Sulfhydryls and Their Role in the Antioxidant Function of Protein S-Thiolation

1995 • 409 citations

Nitric Oxide-induced S-Glutathionylation and Inactivation of Glyceraldehyde-3-phosphate Dehydrogenase

1999 • 316 citations

Redox regulation of c‐Jun DNA binding by reversible S‐glutathiolation

1999 • 285 citations

Regulation of Ubiquitin-conjugating Enzymes by Glutathione Following Oxidative Stress

1997 • 283 citations

Biological disulfides: the third messenger? Modulation of phosphofructokinase activity by thiol/disulfide exchange.

1982 • 265 citations

S-Thiolation of Individual Human Neutrophil Proteins Including Actin by Stimulation of the Respiratory Burst: Evidence against a Role for Glutathione Disulfide

1994 • 228 citations

Mitochondrial Creatine Kinase Is a Prime Target of Peroxynitrite-induced Modification and Inactivation

1998 • 196 citations

S-Glutathiolated Hepatocyte Proteins and Insulin Disulfides as Substrates for Reduction by Glutaredoxin, Thioredoxin, Protein Disulfide Isomerase, and Glutathione

1996 • 186 citations

S-Nitrosylation and S-Glutathiolation of Protein Sulfhydryls byS-Nitroso Glutathione

1999 • 174 citations

S-thiolation of glyceraldehyde-3-phosphate dehydrogenase induced by the phagocytosis-associated respiratory burst in blood monocytes.

1994 • 158 citations

Nitric Oxide Inhibits c-Jun DNA Binding by Specifically TargetedS-Glutathionylation

1999 • 156 citations

The metabolic implications of intracellular circulation

1999 • 139 citations

Velocity of the creatine kinase reaction decreases in postischemic myocardium: a 31P-NMR magnetization transfer study of the isolated ferret heart.

1988 • 134 citations

Reversible inactivation of guanylate cyclase by mixed disulfide formation.

1981 • 132 citations

Creatine Kinase Is the Main Target of Reactive Oxygen Species in Cardiac Myofibrils

1996 • 130 citations

[42] Protein S-thiolation and dethiolation

1994 • 114 citations

Contractile failure and high-energy phosphate turnover during hypoxia: 31P-NMR surface coil studies in living rat.

1987 • 92 citations

Irreversible Inactivation of Protein Kinase C by Glutathione

1998 • 89 citations

Isolation and sequence analysis of a full-length cDNA for human M creatine kinase

1986 • 87 citations

Cellular Responses to Nitric Oxide: Role of Protein S-Thiolation/Dethiolation

1998 • 86 citations

Direct Evidence for Intra- and Intermolecular Disulfide Bond Formation in the Human Glucocorticoid Receptor

1989 • 80 citations

A comparison of protein S-thiolation (protein mixed-disulfide formation) in heart cells treated with t-butyl hydroperoxide or diamide

1986 • 72 citations

S-thiolation of cytoplasmic cardiac creatine kinase in heart cells treated with diamide

1987 • 51 citations

Two tissue-specific isozymes of creatine kinase have closely matched amino acid sequences.

1985 • 50 citations

Regulation of Rat Liver Glycogen Synthetase D

1974 • 42 citations

The presence of reactive SH groups in the enzymatically active dicyano derivative of creatine kinase

1987 • 39 citations

A thin-gel isoelectric focusing method for quantitation of proteins S-thiolation

1986 • 36 citations

Direct Sequence Data from Heterogeneous Creatine Kinase (43 kDa) by High-Resolution Tandem Mass Spectrometry

1995 • 34 citations

Regulatory sulfhydryl groups and activation by homocystine in liver fructose diphosphatase

1970 • 30 citations

Reactivation kinetics of 5,5′-dithiobis-(2-nitrobenzoic acid)-modified creatine kinase reactivated by dithiothreitol

1998 • 24 citations

The effects of Mevinolin on The Thiol/Disulfide Exchange between 3-Hydroxy-3-methyglutaryl-coenzyme A Reductase and Glutathione

1989 • 21 citations

Reduction of protein mixed disulfides (Dethiolation) by Escherichia coli thioredoxin: A study with glycogen phosphorylase b and creatine kinase

1989 • 19 citations

Protein S-Thiolation Can Mediate the Inhibition of Protein Synthesis Induced by tert-Butyl Hydroperoxide in Isolated Rat Hepatocytes

1999 • 12 citations