S-Glutathionylation Decreases Mg2+ Inhibition and S-Nitrosylation Enhances Ca2+ Activation of RyR1 Channels

Free Radicals in the Physiological Control of Cell Function

2002 • 9,561 citations

Determination of protein: A modification of the lowry method that gives a linear photometric response

1972 • 5,490 citations

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

2001 • 4,399 citations

Nitrosylation

2001 • 1,229 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

Ryanodine Receptor Calcium Release Channels

2002 • 1,060 citations

Activation of the Cardiac Calcium Release Channel (Ryanodine Receptor) by Poly-S-Nitrosylation

1998 • 983 citations

Ryanodine Receptor/Ca2+ Release Channels and Their Regulation by Endogenous Effectors

1994 • 908 citations

Regulation of protein function by S‐glutathiolation in response to oxidative and nitrosative stress

2000 • 740 citations

Ryanodine receptors of striated muscles: a complex channel capable of multiple interactions

1997 • 690 citations

Voltage sensor of excitation-contraction coupling in skeletal muscle.

1991 • 593 citations

Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes

2002 • 565 citations

Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol—disulfide status

1999 • 561 citations

The sarcoplasmic reticulum Ca2+ channel/ryanodine receptor: modulation by endogenous effectors, drugs and disease states.

1997 • 549 citations

Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity

2001 • 530 citations

Invited Review: Redox modulation of skeletal muscle contraction: what we know and what we don't

2001 • 449 citations

The Skeletal Muscle Calcium Release Channel

2000 • 429 citations

Nitrosation and oxidation in the regulation of gene expression

2000 • 422 citations

The Biochemistry and Physiology of S-Nitrosothiols

2002 • 408 citations

Endogenous glutathione conjugates: occurrence and biological functions.

1998 • 400 citations

Reversible Glutathionylation of Complex I Increases Mitochondrial Superoxide Formation

2003 • 387 citations

Glutathionylation of the p50 Subunit of NF-κB: a Mechanism for Redox-Induced Inhibition of DNA Binding

2001 • 384 citations

Glutathionylation of human thioredoxin: A possible crosstalk between the glutathione and thioredoxin systems

2002 • 346 citations

Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary.

1994 • 316 citations

Identification of S-glutathionylated cellular proteins during oxidative stress and constitutive metabolism by affinity purification and proteomic analysis

2002 • 315 citations

Cysteine-3635 is responsible for skeletal muscle ryanodine receptor modulation by NO

2001 • 298 citations

Redox regulation of c‐Jun DNA binding by reversible S‐glutathiolation

1999 • 285 citations

Hydrogen Peroxide Stimulates the Ca2+ Release Channel from Skeletal Muscle Sarcoplasmic Reticulum

1995 • 258 citations

Peroxynitrite Modification of Protein Thiols: Oxidation, Nitrosylation, and S-Glutathiolation of Functionally Important Cysteine Residue(s) in the Sarcoplasmic Reticulum Ca-ATPase

1999 • 253 citations

Determination of microgram quantities of protein in the presence of milligram levels of lipid with amido black 10B1

1985 • 239 citations

The Ryanodine Receptor-Ca2+ Release Channel Complex of Skeletal Muscle Sarcoplasmic Reticulum

1989 • 230 citations

Stores Not Just for Storage

2001 • 223 citations

Calmodulin Binding and Inhibition of Cardiac Muscle Calcium Release Channel (Ryanodine Receptor)

2001 • 217 citations

Sulfhydryl Oxidation Modifies the Calcium Dependence of Ryanodine-Sensitive Calcium Channels of Excitable Cells

1998 • 204 citations

Protein–protein interactions in intracellular Ca2+-release channel function

1999 • 197 citations

Reversible S-glutathionylation of Cys374 regulates actin filament formation by inducing structural changes in the actin molecule

2002 • 195 citations

Transformation of local Ca2+ spikes to global Ca2+ transients: the combinatorial roles of multiple Ca2+ releasing messengers

2002 • 184 citations

Sulfhydryl oxidation induces rapid calcium release from sarcoplasmic reticulum vesicles.

1986 • 175 citations

S-Nitrosylation and S-Glutathiolation of Protein Sulfhydryls byS-Nitroso Glutathione

1999 • 174 citations

Prediction of amorphous phase stability in the metal–silicon systems

2001 • 173 citations

Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines

2001 • 169 citations

Regulation of protein phosphatase 2A by hydrogen peroxide and glutathionylation

2002 • 164 citations

S‐Thiolation of human endothelial cell glyceraldehyde‐3‐phosphate dehydrogenase after hydrogen peroxide treatment

1994 • 164 citations

Reactive disulfides trigger Ca2+ release from sarcoplasmic reticulum via an oxidation reaction

1989 • 158 citations

Ryanodine Receptors Contribute to cGMP-Induced Late-Phase LTP and CREB Phosphorylation in the Hippocampus

2002 • 157 citations

Nitric Oxide Inhibits c-Jun DNA Binding by Specifically TargetedS-Glutathionylation

1999 • 156 citations

Classes of Thiols That Influence the Activity of the Skeletal Muscle Calcium Release Channel

2001 • 154 citations

S-nitrosoglutathione reversibly inhibits GAPDH by S-nitrosylation

1995 • 152 citations

Transmembrane Redox Sensor of Ryanodine Receptor Complex

2000 • 145 citations

Superoxide Anion Radical-Triggered Ca²⁺Release from Cardiac Sarcoplasmic Reticulum through Ryanodine Receptor Ca²⁺Channel

1998 • 136 citations

Characterization of multiple [3H]ryanodine binding sites on the Ca2+ release channel of sarcoplasmic reticulum from skeletal and cardiac muscle: evidence for a sequential mechanism in ryanodine action.

1991 • 135 citations

Glutathione Modulates Ryanodine Receptor from Skeletal Muscle Sarcoplasmic Reticulum

1997 • 131 citations

Skeletal Muscle Ryanodine Receptor Is a Redox Sensor with a Well Defined Redox Potential That Is Sensitive to Channel Modulators

2000 • 124 citations

Inactivation of creatine kinase by S-glutathionylation of the active-site cysteine residue

2000 • 118 citations

Nitric Oxide, NOC-12, and S-Nitrosoglutathione Modulate the Skeletal Muscle Calcium Release Channel/Ryanodine Receptor by Different Mechanisms

2003 • 115 citations

Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines

2001 • 110 citations

Dopamine Biosynthesis Is Regulated byS-Glutathionylation

2002 • 102 citations

Multiple Classes of Sulfhydryls Modulate the Skeletal Muscle Ca2+ Release Channel

1997 • 98 citations

Synaptic [Ca2+]

1999 • 94 citations

Thimerosal A versatile sulfhydryl reagent, calcium mobilizer, and cell function-modulating agent

1999 • 93 citations

Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls

1994 • 92 citations

Cellular Responses to Nitric Oxide: Role of Protein S-Thiolation/Dethiolation

1998 • 86 citations

Sulphydryl reagents trigger Ca2+ release from the sarcoplasmic reticulum of skinned rabbit psoas fibres.

1992 • 85 citations

A Role for Cysteine 3635 of RYR1 in Redox Modulation and Calmodulin Binding

1999 • 84 citations

Activation of calcium channels in sarcoplasmic reticulum from frog muscle by nanomolar concentrations of ryanodine

1989 • 81 citations

Thimerosal Interacts with the Ca2+ Release Channel Ryanodine Receptor from Skeletal Muscle Sarcoplasmic Reticulum

1995 • 80 citations

Oxidation of the skeletal muscle Ca²⁺release channel alters calmodulin binding

1999 • 68 citations

RyR1 Modulation by Oxidation and Calmodulin

2000 • 64 citations

Functional Interactions between Cytoplasmic Domains of the Skeletal Muscle Ca2+ Release Channel

1997 • 60 citations

Inactivation of creatine kinase by S-glutathionylation of the active-site cysteine residue

2000 • 60 citations

A Method to Study Kinetics of Transnitrosation with Nitrosoglutathione: Reactions with Hemoglobin and Other Thiols

1997 • 59 citations

Effects of oxidation and cytosolic redox conditions on excitation-contraction coupling in rat skeletal muscle

2003 • 57 citations

Glutathione is a Cofactor for H2O2-Mediated Stimulation of Ca2+-Induced Ca2+ Release in Cardiac Myocytes

1998 • 55 citations

Sulfhydryl Oxidation Overrides Mg2+ Inhibition of Calcium-Induced Calcium Release in Skeletal Muscle Triads

2000 • 54 citations

Triads and transverse tubules isolated from skeletal muscle contain high levels of inositol 1,4,5-trisphosphate

1993 • 54 citations

Reconstitution of the skeletal muscle ryanodine receptor-Ca2+ release channel protein complex into proteoliposomes.

1994 • 51 citations

Redox states of type 1 ryanodine receptor alter Ca²⁺ release channel response to modulators

2002 • 49 citations

Characteristics for a Salt-bridge Switch Mutation of the α1b Adrenergic Receptor

1999 • 46 citations

Effect of S-Nitrosothiols on Cellular Glutathione and Reactive Protein Sulfhydryls

2000 • 42 citations

Specific mixed disulfide formation with purified bovine cardiac glycogen synthase I and glutathione.

1983 • 37 citations

Oxidation and Reduction of Pig Skeletal Muscle Ryanodine Receptors

1999 • 31 citations

Activation and inhibition of purified skeletal muscle calcium release channel by NO donors in single channel current recordings

1999 • 31 citations

H₂O₂and ethanol act synergistically to gate ryanodine receptor/calcium-release channel

2000 • 24 citations

Ryanodine receptor acts as a sensor for redox stress

2001 • 23 citations

Kinetic Studies of Calcium-Induced Calcium Release in Cardiac Sarcoplasmic Reticulum Vesicles

2003 • 23 citations

Sulfhydryl oxidation induces calcium release from fragmented sarcoplasmic reticulum even in the presence of glutathione

1993 • 17 citations

SH Oxidation Stimulates Calcium Release Channels (Ryanodine Receptors) From Excitable Cells

2000 • 15 citations

Modification of sulfhydryls of the skeletal muscle calcium release channel by organic mercurial compounds alters Ca2+ affinity of regulatory Ca2+ sites in single channel recordings and [3H]ryanodine binding

1998 • 13 citations

Detection of Redox Sensor of Ryanodine Receptor Complexes

2002 • 13 citations

Rapid Kinetic Studies of SH Oxidation-Induced Calcium Release from Sarcoplasmic Reticulum Vesicles

1997 • 11 citations