Nucleoredoxin, Glutaredoxin, and Thioredoxin Differentially Regulate NF-κB, AP-1, and CREB Activation in HEK293 Cells

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

1998 • 2,360 citations

Thioredoxin and Glutaredoxin Systems

1989 • 1,778 citations

CREB: a Ca ²⁺ -Regulated Transcription Factor Phosphorylated by Calmodulin-Dependent Kinases

1991 • 1,476 citations

Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide

1997 • 1,208 citations

REDOX REGULATION OF CELLULAR ACTIVATION

1997 • 1,121 citations

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

1997 • 836 citations

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

1997 • 770 citations

Mammalian Peroxiredoxin Isoforms Can Reduce Hydrogen Peroxide Generated in Response to Growth Factors and Tumor Necrosis Factor-α

1998 • 672 citations

Distinct Roles of Thioredoxin in the Cytoplasm and in the Nucleus

1999 • 597 citations

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300

1999 • 583 citations

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase

1999 • 448 citations

Characterization of a Mammalian Peroxiredoxin That Contains One Conserved Cysteine

1998 • 439 citations

Redox Potentials of Glutaredoxins and Other Thiol-Disulfide Oxidoreductases of the Thioredoxin Superfamily Determined by Direct Protein-Protein Redox Equilibria

1997 • 403 citations

[29] Glutaredoxin

1995 • 284 citations

Oxygen and the control of gene expression

1994 • 245 citations

Direct Association with Thioredoxin Allows Redox Regulation of Glucocorticoid Receptor Function

1999 • 205 citations

Reactive oxygen-reducing and protein-refolding activities of adult t cell leukemia-derived factor /human thioredoxin

1992 • 176 citations

Thioredoxin: a redox-regulating cellular cofactor for glucocorticoid hormone action. Cross talk between endocrine control of stress response and cellular antioxidant defense system.

1996 • 170 citations

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.

1996 • 161 citations

Transactivation Domain 2 (TA2) of p65 NF-κB

1995 • 161 citations

Functional modulation of estrogen receptor by redox state with reference to thioredoxin as a mediator

1997 • 133 citations

Cloning and Characterization of the Nucleoredoxin Gene That Encodes a Novel Nuclear Protein Related to Thioredoxin

1997 • 118 citations

Possible Differences in the Regenerative Roles Played by Thioltransferase and Thioredoxin for Oxidatively Damaged Proteins

1994 • 92 citations

Differential expression of glutaredoxin and thioredoxin during monocytic differentiation

1999 • 58 citations

Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: thioredoxin inhibits protein kinase C-mediated phosphorylation of histone

1999 • 51 citations

Thioredoxin Inhibits Tumor Necrosis Factor- or Interleukin-1-Induced NF-κB Activation at a Level Upstream of NF-κB-Inducing Kinase

2000 • 50 citations