Differential gene expression in breast cancer cell lines and stroma–tumor differences in microdissected breast cancer biopsies revealed by display array analysis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Molecular portraits of human breast tumours

2000 • 15,445 citations

The microenvironment of the tumour–host interface

2001 • 2,307 citations

Systematic variation in gene expression patterns in human cancer cell lines

2000 • 2,119 citations

HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C

1998 • 2,114 citations

An Overview of Epithelio-Mesenchymal Transformation

1995 • 1,505 citations

Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway

1994 • 1,015 citations

The plasminogen activation system in tumor growth, invasion, and metastasis

2000 • 930 citations

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

1995 • 821 citations

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

2001 • 751 citations

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

1995 • 385 citations

Negative Regulation of BMP/Smad Signaling by Tob in Osteoblasts

2000 • 326 citations

Structural and Functional Conservation of the Caenorhabditis elegans Timing Gene clk-1

1997 • 309 citations

Positional cloning of ZNF 217 and NABC 1 : Genes amplified at 20q13.2 and overexpressed in breast carcinoma

1998 • 296 citations

Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

2001 • 284 citations

Isolation of a Complementary DNA that Encodes the Mammalian Splicing Factor SC35

1992 • 244 citations

The gene PC3^TIS21/BTG2, prototype member of the PC3/BTG/TOB family: Regulator in control of cell growth, differentiation, and DNA repair?

2001 • 207 citations

Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.

1996 • 190 citations

A rapid procedure for preparing fluorescein-labeled specific antibodies from whole antiserum: its use in analyzing cytoskeletal architecture.

1983 • 189 citations

Genetic model of multi-step breast carcinogenesis involving the epithelium and stroma: clues to tumour-microenvironment interactions

2001 • 189 citations

The nuclear factor kappa B (NF-κB): A potential therapeutic target for estrogen receptor negative breast cancers

2001 • 164 citations

Effects of Fixative and Fixation Time on the Extraction and Polymerase Chain Reaction Amplification of RNA from Paraffin-Embedded Tissue

1994 • 159 citations

A Second Mammalian N-Myristoyltransferase

1998 • 159 citations

Isolation and identification of cross-links from formaldehyde-treated nucleic acids

1980 • 158 citations

The histogenesis of giant cell tumour of bone: a model of interaction between neoplastic cells and osteoclasts.

2001 • 140 citations

Brachyury, the blastopore and the evolution of the mesoderm

2001 • 137 citations

Roles of the matrix metalloproteinases in mammary gland development and cancer

1998 • 132 citations

Yeast Clk-1 Homologue (Coq7/Cat5) Is a Mitochondrial Protein in Coenzyme Q Synthesis

1998 • 131 citations

The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs.

1992 • 131 citations

Association between keratin and vimentin expression, malignant phenotype, and survival in postmenopausal breast cancer patients.

1999 • 128 citations

Locoregionally recurrent breast cancer: incidence, risk factors and survival

2001 • 114 citations

Human Sulfotransferase SULT1C1: cDNA Cloning, Tissue-Specific Expression, and Chromosomal Localization1

1997 • 114 citations

Co-expression of tenascin-C and vimentin in human breast cancer cells indicates phenotypic transdifferentiation during tumour progression: correlation with histopathological parameters, hormone receptors, and oncoproteins

2001 • 112 citations

Differential display

1998 • 106 citations

Human SR Proteins and Isolation of a cDNA Encoding SRp75

1993 • 105 citations

Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

1998 • 103 citations

Protein kinases required for segregation of vimentin filaments in mitotic process

2001 • 98 citations

Assignment of Human Elongation Factor 1α Genes:EEF1AMaps to Chromosome 6q14 andEEF1A2to 20q13.3

1996 • 92 citations

Relationship of transforming growth factor β1 to extracellular matrix and stromal infiltrates in invasive breast carcinoma

1994 • 90 citations

Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer.

2000 • 86 citations

Regulated Expression and RNA Processing of Transcripts from the Srp20 Splicing Factor Gene during the Cell Cycle

1997 • 86 citations

The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A) ⁺ RNA export

1998 • 84 citations

Isolation of an active gene encoding human hnRNP protein A1

1989 • 77 citations

Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I.

1995 • 72 citations

Characterization of a gene that is inversely correlated with estrogen receptor expression (ICERE‐1) in breast carcinomas

1998 • 72 citations

Highly Proliferative Fibroblasts Forming Fibrotic Focus Govern Metastasis of Invasive Ductal Carcinoma of the Breast

2001 • 71 citations

Tissue Microdissection and Degenerate Oligonucleotide Primed-Polymerase Chain Reaction (DOP-PCR) Is an Effective Method to Analyze Genetic Aberrations in Invasive Tumors

2001 • 69 citations

Tumour-stromal interactions. Transforming growth factor-beta isoforms and hepatocyte growth factor/scatter factor in mammary gland ductal morphogenesis.

2001 • 67 citations

Increase in suprabasilar integrin adhesion molecule expression in human epidermal neoplasms accompanies increased proliferation occurring with immortalization and tumor progression.

1995 • 66 citations

N-Myristoyltransferase Overexpression in Human Colorectal Adenocarcinomas

1997 • 66 citations

AP-1 blockade inhibits the growth of normal and malignant breast cells

2001 • 63 citations

Interleukin-4 and breast cancer

2000 • 60 citations

A Human Homolog Can Functionally Replace the Yeast Vesicle-associated SNARE Vti1p in Two Vesicle Transport Pathways

1998 • 59 citations

Individual characterisation of the metastatic capacity of human breast carcinoma

2000 • 58 citations

Interaction between hnRNPA1 and IκBα Is Required for Maximal Activation of NF-κB-Dependent Transcription

2001 • 58 citations

Characterization of the human synaptogyrin gene family

1998 • 56 citations

Characterization of a cDNA defining a gene family encoding TM30pl, a human fibroblast tropomyosin

1987 • 51 citations

Increased expression of N-myristoyltransferase in gallbladder carcinomas

2000 • 51 citations

Aging, progression, and phenotype in breast cancer.

1998 • 49 citations

Human SR proteins and isolation of a cDNA encoding SRp75.

1993 • 49 citations

RNA Extraction from Formalin-Fixed and Paraffin-Embedded Tissues

1998 • 48 citations

The influence of urbanization, age, ethnicity, and income on the early diagnosis of breast carcinoma

2001 • 46 citations

Homology between a Human Protein and a Protein of the Green Garden Pea

1994 • 46 citations

Drosophila Embryos Lacking N-Myristoyltransferase Have Multiple Developmental Defects

2001 • 45 citations

Expression of a repressor of estrogen receptor activity in human breast tumors: relationship to some known prognostic markers.

2000 • 40 citations

Pathology characteristics that optimize outcome prediction of a breast screening trial

2000 • 39 citations

Predicting the biologic behavior of ductal carcinoma in situ: An analysis of molecular markers

2001 • 37 citations

Sequence and transcription patterns of 60S ribosomal protein P0, a diapause-regulated AP endonuclease in the flesh fly, Sarcophaga crassipalpis

2000 • 32 citations

The Oxidative Stress-Sensitive yap1 Null Strain of Saccharomyces cerevisiae Becomes Resistant Due to Increased Carotenoid Levels upon the Introduction of the Chlamydomonas reinhardtii cDNA, Coding for the 60S Ribosomal Protein L10a

2000 • 30 citations

Molecular basis of human natural killer cell recognition of HLA-E (human leucocyte antigen-E) and its relevance to clearance of pathogen-infected and tumour cells

2000 • 29 citations

Cloning and Mapping of Members of the MYM Family

1999 • 28 citations

Isolation of a human cDNA encoding a 25 kDa FK-506 and rapamycin binding protein

1992 • 26 citations

Long-distance DD-PCR and cDNA microarrays

2000 • 23 citations

Overexpression of placental tissue protein 17b/TIP47 in cervical dysplasias and cervical carcinoma.

2001 • 22 citations

Isolation of cDNA coding for the placental protein 15 (PP15)

1988 • 17 citations

Molecular basis of human natural killer cell recognition of HLA-E (human leucocyte antigen-E) and its relevance to clearance of pathogen-infected and tumour cells

2000 • 14 citations

CREBL2,a Novel Transcript from the Chromosome 12 Region Flanked byETV6andCDKN1B

1998 • 13 citations