Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62.

A short amino acid sequence able to specify nuclear location

1984 • 2,529 citations

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence

1991 • 1,501 citations

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

1990 • 909 citations

The GTP-binding protein Ran/TC4 is required for protein import into the nucleus

1993 • 760 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

A polypeptide domain that specifies migration of nucleoplasmin into the nucleus

1982 • 556 citations

Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through nuclear pores

1988 • 551 citations

Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]

1993 • 544 citations

Nuclear import can be separated into distinct steps in vitro: Nuclear pore binding and translocation

1988 • 535 citations

Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.

1987 • 533 citations

Inhibition of in vitro nuclear transport by a lectin that binds to nuclear pores.

1987 • 510 citations

Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.

1987 • 428 citations

Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import

1991 • 391 citations

The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognate.

1992 • 335 citations

Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathway.

1987 • 330 citations

Purification of a Ran-interacting protein that is required for protein import into the nucleus.

1994 • 318 citations

A nuclear pore complex protein that contains zinc finger motifs, binds DNA, and faces the nucleoplasm

1993 • 308 citations

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope.

1994 • 306 citations

The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors

1992 • 278 citations

Facilitated nuclear transport of histone H1 and other small nucleophilic proteins

1990 • 278 citations

Characterization of proteins that interact with the cell-cycle regulatory protein Ran/TC4

1993 • 261 citations

Toward a more complete 3-D structure of the nuclear pore complex

1991 • 254 citations

The human CAN protein, a putative oncogene productassociated with myeloid leukemogenesis, is a nuclear pore complex protein thatfaces the cytoplasm.

1994 • 238 citations

Structure and Function of the Nuclear Pore Complex

1992 • 237 citations

Reversible inhibition of protein import into the nucleus by wheat germ agglutinin injected into cultured cells

1987 • 233 citations

A complex of nuclear pore proteins required for pore function.

1991 • 231 citations

Reconstitution of biochemically altered nuclear pores: Transport can be eliminated and restored

1990 • 228 citations

In vitro transport of a fluorescent nuclear protein and exclusion of non-nuclear proteins.

1986 • 211 citations

Isolation and characterization of the active cDNA of the human cell cycle gene (RCC1) involved in the regulation of onset of chromosome condensation.

1987 • 208 citations

A monoclonal antibody against the nuclear pore complex inhibits nucleocytoplasmic transport of protein and RNA in vivo.

1988 • 206 citations

Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis.

1993 • 195 citations

NSP1: A yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain

1990 • 180 citations

The nuclear pore complex

1993 • 166 citations

Inhibition of nuclear accumulation of karyophilic proteins in living cells by microinjection of the lectin wheat germ agglutinin

1988 • 146 citations

Primary sequence and heterologous expression of nuclear pore glycoprotein p62.

1990 • 137 citations

Cytoplasmic transport of ribosomal subunits microinjected into the Xenopus laevis oocyte nucleus: a generalized, facilitated process.

1990 • 135 citations

An N-ethylmaleimide-sensitive cytosolic factor necessary for nuclear protein import: requirement in signal-mediated binding to the nuclear pore.

1990 • 128 citations

Nuclear pore complex glycoprotein p62 of Xenopus laevis and mouse: cDNA cloning and identification of its glycosylated region.

1991 • 123 citations

Export of mRNA from microinjected nuclei of Xenopus laevis oocytes.

1992 • 121 citations

NUP2, a novel yeast nucleoporin, has functional overlap with other proteins of the nuclear pore complex.

1993 • 119 citations

Molecular trafficking across the nuclear pore complex

1992 • 114 citations

Identification of a soluble precursor complex essential for nuclear pore assembly in vitro

1990 • 104 citations

The Transport of Proteins into the Nucleus Requires the 70-Kilodalton Heat Shock Protein or Its Cytosolic Cognate

1992 • 92 citations

Nuclear transport

1994 • 89 citations

The nuclear pore: at the crossroads

1992 • 83 citations

O-linked glycoproteins of the nuclear pore complex interact with a cytosolic factor required for nuclear protein import.

1992 • 66 citations

Are the cytosolic components of the nuclear, ER, and mitochondrial import apparatus functionally related?

1992 • 42 citations

Internal Amino Acid Sequence Analysis of Proteins after in Situ Protease Digestion on Nitrocellulose

1993 • 30 citations

Isolation of cDNA coding for the placental protein 15 (PP15)

1988 • 17 citations