Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis

1996 • 6,878 citations

Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity

1995 • 1,608 citations

Isolation and Characterization of a Spontaneously Immortalized Human Breast Epithelial Cell Line, MCF-10

1990 • 1,495 citations

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells.

1987 • 591 citations

Fibroblast-mediated acceleration of human epithelial tumor growth in vivo.

1990 • 417 citations

Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis.

2000 • 400 citations

Stromal-epithelial interactions in adult organs

1985 • 315 citations

MCF10AT: a model for the evolution of cancer from proliferative breast disease.

1996 • 298 citations

Alterations in expression of basic fibroblast growth factor (FGF) 2 and its receptor FGFR-1 in human prostate cancer.

1999 • 277 citations

Influence of age and parity on the development of the human breast

1992 • 232 citations

Psoriatic Fibroblasts Induce Hyperproliferation of Normal Keratinocytes in a Skin Equivalent Model in Vitro

1985 • 220 citations

Intratumoral Aromatase in Human Breast, Endometrial, and Ovarian Malignancies*

1998 • 215 citations

Xenograft Model of Progressive Human Proliferative Breast Disease

1993 • 204 citations

Ultrastructural and immunocytochemical characterization of an immortalized human breast epithelial cell line, MCF-10.

1990 • 203 citations

Genetic events and the role of TGFβ in epithelial tumour progression

1999 • 166 citations

Transformation of Human Breast Epithelial Cells by c‐Ha‐ras Oncogene

1991 • 162 citations

Stromal regulation of epithelial function

1991 • 154 citations

Purification of the migration stimulating factor produced by fetal and breast cancer patient fibroblasts.

1989 • 153 citations

Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: evidence for paracrine function.

1995 • 134 citations

Breast Cancer and the Role of Cytokines in Regulating Estrogen Synthesis: An Emerging Hypothesis

1997 • 131 citations

Fibroblast-dependent tumorigenicity of cells in nude mice: implication for implantation of metastases.

1986 • 126 citations

The role of fibroblasts in tumor behavior

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Intrauterine transplantation of rat basal cell carcinoma as a model for reconversion of malignant to benign growth.

1977 • 112 citations

Mesenchyme-induced changes in the neoplastic characteristics of the Dunning prostatic adenocarcinoma.

1991 • 101 citations

Vascular Permeability Factor/Vascular Endothelial Growth Factor Inhibits Anchorage-Disruption-Induced Apoptosis in Microvessel Endothelial Cells by Inducing Scaffold Formation

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Role of Basement Membranes in Cell Differentiation

1987 • 96 citations

Uterine and Vaginal Organ Growth Requires Epidermal Growth Factor Receptor Signaling from Stroma*

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Stromal aspects of breast carcinoma

1979 • 80 citations

Interaction with endothelial cells is a prerequisite for branching ductal-alveolar morphogenesis and hyperplasia of preneoplastic human breast epithelial cells: regulation by estrogen.

2000 • 63 citations

Hormonal regulation of insulin-like growth factor II and insulin-like growth factor binding protein expression by breast cancer cells in vivo: evidence for stromal epithelial interactions.

1994 • 51 citations

Phenotypic heterogeneity in breast fibroblasts: Functional anomaly in fibroblasts from histologically normal tissue adjacent to carcinoma

1994 • 50 citations

Direct action of estrogen on sequence of progression of human preneoplastic breast disease.

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Hepatocyte Growth Factor Is a Paracrine Regulator of Rat Prostate Epithelial Growth

1996 • 42 citations

RegulatedCYP19Aromatase Transcription in Breast Stromal Fibroblasts¹

2000 • 29 citations

The stroma and the control of cell growth

1986 • 27 citations