Tumour-stromal interactions. Transforming growth factor-beta isoforms and hepatocyte growth factor/scatter factor in mammary gland ductal morphogenesis.

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2000 • 2,354 citations

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2000 • 1,843 citations

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2000 • 1,806 citations

Thrombospondin-1 Is a Major Activator of TGF-β1 In Vivo

1998 • 1,151 citations

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors.

1994 • 937 citations

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

2001 • 549 citations

Signaling of transforming growth factor‐β family members through Smad proteins

2000 • 530 citations

Postnatal mammary gland development requires macrophages and eosinophils

2000 • 429 citations

Reversible Inhibition of Mammary Gland Growth by Transforming Growth Factor-β

1987 • 408 citations

Think globally, act locally: the making of a mouse mammary gland

1998 • 269 citations

Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1.

1993 • 260 citations

Essential Role of Gab1 for Signaling by the C-Met Receptor in Vivo

2000 • 255 citations

Regulated expression and growth inhibitory effects of transforming growth factor-β isoforms in mouse mammary gland development

1991 • 228 citations

Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.

1993 • 224 citations

Targeted mutations of transforming growth factor‐β genes reveal important roles in mouse development and adult homeostasis

2000 • 210 citations

Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland.

1993 • 208 citations

Ectopic TGFβ1 Expression in the Secretory Mammary Epithelium Induces Early Senescence of the Epithelial Stem Cell Population

1995 • 182 citations

TGF-β1-induced inhibition of mouse mammary ductal growth: Developmental specificity and characterization

1989 • 174 citations

Transforming growth factor β3 induces cell death during the first stage of mammary gland involution

2000 • 173 citations

HGF/SF: a potent cytokine for mammary growth, morphogenesis and development

1995 • 171 citations

Transforming Growth Factor-β1 Inhibition of Macrophage Activation Is Mediated via Smad3

2000 • 167 citations

Laminin and β1 Integrins Are Crucial for Normal Mammary Gland Development in the Mouse

1999 • 136 citations

Reconstitution of Mammary Gland Development In Vitro: Requirement of c-met and c-erbB2 Signaling for Branching and Alveolar Morphogenesis

1998 • 131 citations

Overexpression of a Kinase-deficient Transforming Growth Factor-β Type II Receptor in Mouse Mammary Stroma Results in Increased Epithelial Branching

1999 • 122 citations

Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice.

1998 • 113 citations

Signal transduction in mammary tumorigenesis: a transgenic perspective

2000 • 97 citations

TGF beta suppresses casein synthesis in mouse mammary explants and may play a role in controlling milk levels during pregnancy.

1993 • 90 citations

The role of mammary stroma in modulating the proliferative response to ovarian hormones in the normal mammary gland.

1998 • 83 citations

Transforming growth factor-β and breast cancer: Mammary gland development

2000 • 77 citations

Roles of hepatocyte growth factor/scatter factor and transforming growth factor-beta1 in mammary gland ductal morphogenesis.

1998 • 67 citations

Expression of transforming growth factors alpha and beta-1 messenger RNA in the bovine mammary gland during different stages of development and lactation

1997 • 66 citations

Immunocytochemical localization of latent transforming growth factor-?1 activation by stimulated macrophages

1999 • 54 citations

Dominant negative Met reduces tumorigenicity-metastasis and increases tubule formation in mammary cells

2000 • 54 citations

Transforming growth factor-β and breast cancer: Lessons learned from genetically altered mouse models

2000 • 49 citations

Transforming Growth Factor-β Inhibits Lactogenic Hormone Induction of β-Casein Expression in HC11 Mouse Mammary Epithelial Cells

1990 • 46 citations

Differential expression of TGF-β isoforms during postlactational mammary gland involution

2000 • 45 citations

In VivoEffects of Hepatocyte Growth Factor/Scatter Factor on Mouse Mammary Gland Development

1998 • 43 citations

HGF/SF in mammary epithelial growth and morphogenesis: in vitro and in vivo models.

1999 • 41 citations

Stimulation of DNA Synthesis and Cell Proliferation of Human Mammary Myoepithelial-like Cells by Hepatocyte Growth Factor/Scatter Factor Depends on Heparan Sulfate Proteoglycans and Sustained Phosphorylation of Mitogen-activated Protein Kinases p42/44

2000 • 39 citations

Expression and secretion of TGF-beta isoforms and expression of TGF-beta-receptors I, II and III in normal and neoplastic human breast.

1999 • 33 citations

Met signaling mutants as tools for developmental studies.

2000 • 20 citations

Modulation of transforming growth factor beta1 gene expression in the mammary gland by insulin-like growth factor I and octreotide.

2000 • 9 citations