Regulation of molecular motor proteins

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Three-dimensional structure of myosin subfragment-1: a molecular motor

1993 • 2,027 citations

Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport

1998 • 1,634 citations

The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex

1999 • 1,045 citations

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

1995 • 940 citations

Localization of Protein Kinases by Anchoring Proteins: a Theme in Signal Transduction

1995 • 911 citations

Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease

1998 • 800 citations

Myosin-V is a processive actin-based motor

1999 • 787 citations

Adenosine Triphosphate-Induced Sliding of Tubules in Trypsin-Treated Flagella of Sea-Urchin Sperm

1971 • 702 citations

Kin I Kinesins Are Microtubule-Destabilizing Enzymes

1999 • 697 citations

Myosin VI is an actin-based motor that moves backwards

1999 • 664 citations

Dynactin increases the processivity of the cytoplasmic dynein motor

1999 • 660 citations

Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction

1998 • 649 citations

The neuron-specific kinesin superfamily protein KIF1A is a uniqye monomeric motor for anterograde axonal transport of synaptic vesicle precursors

1995 • 646 citations

Targeted Disruption of Mouse Conventional Kinesin Heavy Chain kif5B, Results in Abnormal Perinuclear Clustering of Mitochondria

1998 • 643 citations

AKAPs: from structure to function

1999 • 619 citations

KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria

1994 • 584 citations

Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons

1992 • 569 citations

Novel myosin heavy chain encoded by murine dilute coat colour locus

1991 • 534 citations

Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons.

1995 • 533 citations

Acanthamoeba Myosin

1973 • 513 citations

ARF mediates recruitment of PtdIns-4-OH kinase-β and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex

1999 • 513 citations

The periodic association of MAP2 with brain microtubules in vitro.

1979 • 510 citations

Interaction of a Golgi-Associated Kinesin-Like Protein with Rab6

1998 • 508 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

Rab5 regulates motility of early endosomes on microtubules

1999 • 504 citations

Mating Type Switching in Yeast Controlled by Asymmetric Localization of ASH1 mRNA

1997 • 493 citations

Cytoplasmic dynein is localized to kinetochores during mitosis

1990 • 486 citations

Rhodopsin’s Carboxy-Terminal Cytoplasmic Tail Acts as a Membrane Receptor for Cytoplasmic Dynein by Binding to the Dynein Light Chain Tctex-1

1999 • 478 citations

The Saccharomyces cerevisiae MYO2 gene encodes an essential myosin for vectorial transport of vesicles.

1991 • 471 citations

The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly

1999 • 470 citations

THE DESIGN PLAN OF KINESIN MOTORS

1997 • 468 citations

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.

1995 • 466 citations

Microtubules and microtubule-associated proteins

1995 • 465 citations

Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

1989 • 460 citations

Cytoplasmic dynein and dynactin in cell division and intracellular transport

1999 • 454 citations

A Processive Single-Headed Motor: Kinesin Superfamily Protein KIF1A

1999 • 453 citations

Brain myosin-V is a two-headed unconventional myosin with motor activity

1993 • 432 citations

Rab6 Coordinates a Novel Golgi to ER Retrograde Transport Pathway in Live Cells

1999 • 413 citations

Visualization of Melanosome Dynamics within Wild-Type and Dilute Melanocytes Suggests a Paradigm for Myosin V Function In Vivo

1998 • 407 citations

Bending patterns of Chlamydomonas flagella: IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function

1987 • 396 citations

Developmental Regulation of Vesicle Transport in Drosophila Embryos: Forces and Kinetics

1998 • 389 citations

Rho as a regulator of the cytoskeleton

1995 • 386 citations

Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast

1997 • 386 citations

Human Bubr1 Is a Mitotic Checkpoint Kinase That Monitors Cenp-E Functions at Kinetochores and Binds the Cyclosome/APC

1999 • 379 citations

Molecular mechanisms of nonmuscle myosin-II regulation

1999 • 376 citations

Actin-dependent organelle movement in squid axoplasm

1992 • 370 citations

Cytoplasmic Dynein, the Dynactin Complex, and Kinesin Are Interdependent and Essential for Fast Axonal Transport

1999 • 365 citations

A bipolar kinesin

1996 • 365 citations

Unconventional Myosins

1995 • 362 citations

Asymmetric Accumulation of Ash1p in Postanaphase Nuclei Depends on a Myosin and Restricts Yeast Mating-Type Switching to Mother Cells

1996 • 355 citations

Dynactin Is Required for Microtubule Anchoring at Centrosomes

1999 • 354 citations

Submicromolar levels of calcium control the balance of beating between the two flagella in demembranated models of Chlamydomonas.

1984 • 352 citations

The molecular basis for tropomyosin isoform diversity

1991 • 350 citations

Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains.

1992 • 345 citations

Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis.

1994 • 344 citations

Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles

1999 • 342 citations

pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis

1998 • 341 citations

Affinity Chromatography Demonstrates a Direct Binding between Cytoplasmic Dynein and the Dynactin Complex

1995 • 338 citations

Rapid Movements of Vimentin on Microtubule Tracks: Kinesin-dependent Assembly of Intermediate Filament Networks

1998 • 337 citations

MAPs, MARKs and microtubule dynamics

1998 • 337 citations

Cytoplasmic Dynein Heavy Chain 1b Is Required for Flagellar Assembly inChlamydomonas

1999 • 335 citations

Direct interaction of microtubule- and actin-based transport motors

1999 • 329 citations

Tropomyosin crystal structure and muscle regulation

1986 • 324 citations

The role of Myo2, a yeast class V myosin, in vesicular transport.

1995 • 324 citations

Rab GTPases, Directors of Vesicle Docking

1998 • 322 citations

The Kinesin-Related Protein, Hset, Opposes the Activity of Eg5 and Cross-Links Microtubules in the Mammalian Mitotic Spindle

1999 • 321 citations

The Bipolar Kinesin, KLP61F, Cross-links Microtubules within Interpolar Microtubule Bundles of Drosophila Embryonic Mitotic Spindles

1999 • 317 citations

Rapid movement of axonal neurofilaments interrupted by prolonged pauses

2000 • 316 citations

Kinesin’s tail domain is an inhibitory regulator of the motor domain

1999 • 312 citations

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1).

1995 • 307 citations

Role of a Class Dhc1b Dynein in Retrograde Transport of Ift Motors and Ift Raft Particles along Cilia, but Not Dendrites, in Chemosensory Neurons of Living Caenorhabditis elegans

1999 • 305 citations

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

1996 • 301 citations

Binding of myosin I to membrane lipids

1989 • 287 citations

Kinesin Is a Candidate for Cross-bridging Microtubules and Intermediate Filaments

1998 • 283 citations

Single-molecule analysis of kinesin motility reveals regulation by the cargo-binding tail domain

1999 • 281 citations

Characterization of the Kinetochore Binding Domain of CENP-E Reveals Interactions with the Kinetochore Proteins CENP-F and hBUBR1

1998 • 280 citations

Radial extension of macrophage tubular lysosomes supported by kinesin

1990 • 276 citations

Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin.

1994 • 275 citations

Protein Kinase A Anchoring

1997 • 272 citations

Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle.

1995 • 269 citations

The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3

1998 • 266 citations

Plk Is an M-Phase-Specific Protein Kinase and Interacts with a Kinesin-Like Protein, CHO1/MKLP-1

1995 • 266 citations

Calcium couples flagellar reversal to photostimulation in Chlamydomonas reinhardtii

1976 • 255 citations

Kinesin associates with anterogradely transported membranous organelles in vivo.

1991 • 254 citations

The Road Less Traveled: Emerging Principles of Kinesin Motor Utilization

1999 • 254 citations

Light Chain– dependent Regulation of Kinesin's Interaction with Microtubules

1998 • 252 citations

The small GTP-binding protein rab6 functions in intra-Golgi transport.

1994 • 251 citations

The Cooh-Terminal Domain of Myo2p, a Yeast Myosin V, Has a Direct Role in Secretory Vesicle Targeting

1999 • 247 citations

Antagonistic microtubule-sliding motors position mitotic centrosomes in Drosophila early embryos

1999 • 246 citations

Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic [published errata appear in J Cell Biol 1995 Mar;128(5):following 988 and 1995 May;129(3):893]

1995 • 243 citations

Brain Myosin V Is a Synaptic Vesicle-associated Motor Protein: Evidence for a Ca2+-dependent Interaction with the Synaptobrevin–Synaptophysin Complex

1997 • 243 citations

The Xenopus protein kinase pEg2 associates with the centrosome in a cell cycle-dependent manner, binds to the spindle microtubules and is involved in bipolar mitotic spindle assembly

1998 • 240 citations

Functional Coordination of Three Mitotic Motors inDrosophilaEmbryos

2000 • 238 citations

Xklp15 a chromosomal xenopus kinesin-like protein essential for spindle organization and chromosome positioning

1995 • 237 citations

A motile Chlamydomonas flagellar mutant that lacks outer dynein arms.

1985 • 237 citations

Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules

1997 • 232 citations

Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport.

1995 • 230 citations

Synthetic lethality screen identifies a novel yeast myosin I gene (MYO5): myosin I proteins are required for polarization of the actin cytoskeleton.

1996 • 229 citations

Propulsion of organelles isolated from Acanthamoeba along actin filaments by myosin-I

1986 • 227 citations

Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor

1997 • 227 citations

Coalignment of vimentin intermediate filaments with microtubules depends on kinesin

1991 • 226 citations

Endosome dynamics regulated by a Rho protein

1996 • 225 citations

Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro

1997 • 222 citations

Mitotic Spindle Poles are Organized by Structural and Motor Proteins in Addition to Centrosomes

1997 • 220 citations

The Xenopus laevis Aurora-related Protein Kinase pEg2 Associates with and Phosphorylates the Kinesin-related Protein XlEg5

1999 • 218 citations

Porcine myosin-VI: characterization of a new mammalian unconventional myosin.

1994 • 218 citations

Active MAP Kinase in Mitosis: Localization at Kinetochores and Association with the Motor Protein CENP-E

1998 • 215 citations

The Rho GTPase Rho3 Has a Direct Role in Exocytosis That Is Distinct from Its Role in Actin Polarity

1999 • 214 citations

The inner dynein arms I2 interact with a "dynein regulatory complex" in Chlamydomonas flagella.

1992 • 213 citations

Casein kinase II is a predominantly nuclear enzyme.

1992 • 208 citations

Kinesin- and Myosin-driven Steps of Vesicle Recruitment for Ca2+-regulated Exocytosis

1997 • 208 citations

Molecular motors are differentially distributed on Golgi membranes from polarized epithelial cells.

1994 • 208 citations

Analysis of RhoA-binding Proteins Reveals an Interaction Domain Conserved in Heterotrimeric G Protein β Subunits and the Yeast Response Regulator Protein Skn7

1998 • 208 citations

Brain Cytoplasmic and Flagellar Outer Arm Dyneins Share a Highly Conserved Mr 8,000 Light Chain

1996 • 207 citations

Direct Interaction of Pericentrin with Cytoplasmic Dynein Light Intermediate Chain Contributes to Mitotic Spindle Organization

1999 • 203 citations

Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organelles.

1996 • 203 citations

Actin and myosin function in directed vacuole movement during cell division in Saccharomyces cerevisiae.

1996 • 203 citations

Drosophila Polo Kinase Is Required for Cytokinesis

1998 • 203 citations

Transport of ER vesicles on actin filaments in neurons by myosin V

1998 • 200 citations

The Localization of Myosin VI at the Golgi Complex and Leading Edge of Fibroblasts and Its Phosphorylation and Recruitment into Membrane Ruffles of A431 Cells after Growth Factor Stimulation

1998 • 198 citations

Dictyostelium myosin I double mutants exhibit conditional defects in pinocytosis.

1995 • 198 citations

Rho3 of Saccharomyces cerevisiae, Which Regulates the Actin Cytoskeleton and Exocytosis, Is a GTPase Which Interacts with Myo2 and Exo70

1999 • 194 citations

Membrane trafficking, organelle transport, and the cytoskeleton

2000 • 192 citations

Golgi-derived vesicles from developing epithelial cells bind actin filaments and possess myosin-I as a cytoplasmically oriented peripheral membrane protein.

1993 • 192 citations

Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B.

1996 • 188 citations

Functional coordination of microtubule-based and actin-based motility in melanophores

1998 • 187 citations

Myosin II Is Involved in the Production of Constitutive Transport Vesicles from the TGN

1997 • 184 citations

Calmodulin dissociation regulates brush border myosin I (110-kD-calmodulin) mechanochemical activity in vitro.

1990 • 184 citations

cAMP-stimulated phosphorylation of an axonemal polypeptide that copurifies with the 22S dynein arm regulates microtubule translocation velocity and swimming speed in Paramecium.

1991 • 183 citations

Involvement of microtubule motors in basolateral and apical transport in kidney cells

1994 • 183 citations

Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles.

1994 • 180 citations

A Novel Plant Calmodulin-binding Protein with a Kinesin Heavy Chain Motor Domain

1996 • 179 citations

TEDS rule: A molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain head

1995 • 179 citations

The distribution, abundance and subcellular localization of kinesin.

1989 • 179 citations

Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End

1999 • 177 citations

The M = 8,000 and 11,000 Outer Arm Dynein Light Chains from Chlamydomonas Flagella Have Cytoplasmic Homologues

1995 • 176 citations

Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.

1996 • 176 citations

Tissue distribution and subcellular localization of mammalian myosin I.

1992 • 175 citations

Highly processive microtubule-stimulated ATP hydrolysis by dimeric kinesin head domains

1995 • 174 citations

Cultured melanocytes from dilute mutant mice exhibit dendritic morphology and altered melanosome distribution

1996 • 173 citations

Regulation of Flagellar Dynein by Phosphorylation of a 138-kD Inner Arm Dynein Intermediate Chain

1997 • 171 citations

Kinesin undergoes a 9 S to 6 S conformational transition.

1992 • 169 citations

TKRP125, a kinesin-related protein involved in the centrosome-independent organization of the cytokinetic apparatus in tobacco BY-2 cells

1997 • 168 citations

Chromosomal Control of Meiotic Cell Division

1995 • 166 citations

The 78,000 M(r) intermediate chain of Chlamydomonas outer arm dynein isa WD-repeat protein required for arm assembly.

1995 • 165 citations

Components of a "dynein regulatory complex" are located at the junction between the radial spokes and the dynein arms in Chlamydomonas flagella.

1994 • 164 citations

Phosphoregulation of an Inner Dynein Arm Complex in Chlamydomonas reinhardtii Is Altered in Phototactic Mutant Strains

1997 • 163 citations

Cell cycle regulation of dynein association with membranes modulates microtubule-based organelle transport.

1996 • 163 citations

Mitotic spindle function in Saccharomyces cerevisiae requires a balance between different types of kinesin-related motors.

1997 • 162 citations

Interaction of Kinesin Motor Domains with α- and β-Tubulin Subunits at a Tau-independent Binding Site

1996 • 162 citations

Binding of brush border myosin I to phospholipid vesicles.

1990 • 160 citations

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

1994 • 160 citations

Drosophila roadblock and Chlamydomonas Lc7

1999 • 158 citations

Formation of the Compact Confomer of Kinesin Requires a COOH-terminal Heavy Chain Domain and Inhibits Microtubule-stimulated ATPase Activity

1999 • 156 citations

The phosphorylation of kinesin regulates its binding to synaptic vesicles.

1992 • 156 citations

Regulation of Membrane Trafficking

1999 • 155 citations

Rotation of the Central Pair Microtubules in Eukaryotic Flagella

1999 • 153 citations

Cloning and localization of a conventional kinesin motor expressed exclusively in neurons

1994 • 151 citations

Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis.

1994 • 151 citations

Myosin VA Movements in Normal and Dilute-Lethal Axons Provide Support for a Dual Filament Motor Complex

1999 • 149 citations

Kid, a novel kinesin-like DNA binding protein, is localized to chromosomes and the mitotic spindle.

1996 • 149 citations

The unconventional myosin encoded by the myoA gene plays a role in Dictyostelium motility.

1993 • 148 citations

Mitotic Regulation of Microtubule Cross-Linking Activity of CENP-E Kinetochore Protein

1994 • 148 citations

The dilute-lethal (d) gene attacks a Ca2+ store in the dendritic spine of Purkinje cells in mice

1996 • 147 citations

DNA binding and meiotic chromosomal localization of the drosophila nod kinesin-like protein

1995 • 147 citations

The Role of the Dynactin Complex in Intracellular Motility

1998 • 145 citations

Phosphorylation by p34cdc2 Protein Kinase Regulates Binding of the Kinesin-related Motor HsEg5 to the Dynactin Subunit p150Glued

1997 • 145 citations

Focusing on spindle poles

1998 • 143 citations

An unconventional myosin heavy chain gene from Drosophila melanogaster.

1992 • 143 citations

Myosin IB null mutants of Dictyostelium exhibit abnormalities in motility

1991 • 143 citations

Sequence and submolecular localization of the 115-kD accessory subunit of the heterotrimeric kinesin-II (KRP85/95) complex.

1996 • 142 citations

Vesicle-associated brain myosin-V can be activated to catalyze actin-based transport

1998 • 139 citations

The 110,000-dalton actin- and calmodulin-binding protein from intestinal brush border is a myosin-like ATPase.

1984 • 138 citations

Retroviral sequences located within an intron of the dilute gene alter dilute expression in a tissue-specific manner.

1995 • 138 citations

The role of central apparatus components in flagellar motility and microtubule assembly

1997 • 138 citations

Characterization of KIF1C, a New Kinesin-like Protein Involved in Vesicle Transport from the Golgi Apparatus to the Endoplasmic Reticulum

1998 • 137 citations

Axonemal dyneins: assembly, organization, and regulation

1996 • 137 citations

In vitro motility of AtKCBP, a calmodulin-binding kinesin protein of Arabidopsis

1997 • 137 citations

The terminal tail region of a yeast myosin-V mediates its attachment to vacuole membranes and sites of polarized growth

1998 • 136 citations

The bimC family of kinesins: essential bipolar mitotic motors driving centrosome separation

1997 • 134 citations

Myosin I

1997 • 132 citations

Chromokinesin: a DNA-binding, kinesin-like nuclear protein.

1995 • 132 citations

Cooperation Between Microtubule- and Actin-Based Motor Proteins

1999 • 131 citations

Regulation of Melanosome Movement in the Cell Cycle by Reversible Association with Myosin V

1999 • 130 citations

Identification of MYO4, a second class V myosin gene in yeast

1994 • 130 citations

Localization and specificity of the phospholipid and actin binding sites on the tail of Acanthamoeba myosin IC

1992 • 130 citations

A Class VI Unconventional Myosin Is Associated with a Homologue of a Microtubule-binding Protein, Cytoplasmic Linker Protein–170, in Neurons and at the Posterior Pole of Drosophila Embryos

1998 • 130 citations

Dimerization of the Highly Conserved Light Chain Shared by Dynein and Myosin V

1997 • 129 citations

Identification of a Microtubule-associated Motor Protein Essential for Dendritic Differentiation

1997 • 129 citations

Acanthamoeba cofactor protein is a heavy chain kinase required for actin activation of the Mg2+-ATPase activity of Acanthamoeba myosin I

1977 • 126 citations

Characterization of a Chlamydomonas Insertional Mutant that Disrupts Flagellar Central Pair Microtubule-associated Structures

1999 • 125 citations

The heavy chain of Acanthamoeba myosin IB is a fusion of myosin-like and non-myosin-like sequences.

1987 • 125 citations

Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein

1994 • 124 citations

Cytoplasmic Dynein Contains a Family of Differentially Expressed Light Chains

1998 • 123 citations

Localization of a kinesin‐like calmodulin‐binding protein in dividing cells of Arabidopsis and tobacco

1997 • 123 citations

Enzymatic Characterization and Functional Domain Mapping of Brain Myosin-V

1996 • 122 citations

The proximal portion of Chlamydomonas flagella contains a distinct set of inner dynein arms.

1991 • 122 citations

Immunocytochemical localization of casein kinase II during interphase and mitosis.

1991 • 122 citations

Kinesin-Related Proteins at Mitotic Spindle Poles: Function and Regulation

1996 • 121 citations

Homology of the 74-kD cytoplasmic dynein subunit with a flagellar dynein polypeptide suggests an intracellular targeting function.

1992 • 120 citations

Plasma membrane association of Acanthamoeba myosin I.

1989 • 120 citations

Inhibition of contractile vacuole function in vivo by antibodies against myosin-I

1993 • 120 citations

Dynein motor regulation stabilizes interphase microtubule arrays and determines centrosome position

1999 • 120 citations

Transport of cytoplasmic particles catalysed by an unconventional myosin in living Drosophila embryos

1994 • 120 citations

Effects of Kinesin Mutations on Neuronal Functions

1992 • 117 citations

Identification of a Ca2+-binding light chain within Chlamydomonas outer arm dynein

1995 • 114 citations

Protein phosphatase 1 regulates the cytoplasmic dynein-driven formation of endoplasmic reticulum networks in vitro.

1995 • 114 citations

Microtubule motors in spindle and chromosome motility

1999 • 114 citations

Regulation of calmodulin-binding myosins

1995 • 113 citations

Differential Regulation of the Kar3p Kinesin-related Protein by Two Associated Proteins, Cik1p and Vik1p

1999 • 113 citations

Phosphorylation of Kinesin inVivo Correlates with Organelle Association and Neurite Outgrowth

1995 • 112 citations

Biochemical and immunological characterization of p190-calmodulin complex from vertebrate brain: a novel calmodulin-binding myosin.

1992 • 112 citations

Steric inhibition of cytoplasmic dynein and kinesin motility by MAP2

1993 • 111 citations

Phosphorylation of Neuronal Kinesin Heavy and Light Chains In Vivo

1993 • 110 citations

Differential localization of Acanthamoeba myosin I isoforms.

1992 • 110 citations

Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase.

1994 • 109 citations

Splitting the ciliary axoneme: Implications for a “Switch‐Point” model of dynein arm activity in ciliary motion

1989 • 109 citations

KIF3C and KIF3A Form a Novel Neuronal Heteromeric Kinesin That Associates with Membrane Vesicles

1998 • 109 citations

A Specific Light Chain of Kinesin Associates with Mitochondria in Cultured Cells

1998 • 108 citations

The Involvement of the Intermediate Chain of Cytoplasmic Dynein in Binding the Motor Complex to Membranous Organelles ofXenopusOocytes

1997 • 107 citations

Identification, characterization and cloning of myr 1, a mammalian myosin-I.

1993 • 107 citations

Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains

1995 • 107 citations

Rat myr 4 defines a novel subclass of myosin I: identification, distribution, localization, and mapping of calmodulin-binding sites with differential calcium sensitivity.

1994 • 106 citations

Proteasomes regulate the motility of salmonid fish sperm through modulation of cAMP-dependent phosphorylation of an outer arm dynein light chain

1998 • 106 citations

Microtubule-based membrane movement

1998 • 105 citations

Characterization of the KIF3C Neural Kinesin-like Motor from Mouse

1998 • 104 citations

Myosin II is associated with Golgi membranes: identification of p200 as nonmuscle myosin II on Golgi-derived vesicles

1997 • 102 citations

Association of the class V myosin Myo4p with a localised messenger RNA in budding yeast depends on She proteins

1999 • 102 citations

ATPase activities and actin-binding properties of subfragments of Acanthamoeba myosin IA.

1986 • 101 citations

Activation of Myosin-I by Members of the Ste20p Protein Kinase Family

1996 • 100 citations

Protein phosphatases PP1 and PP2A are located in distinct positions in the Chlamydomonas flagellar axoneme

2000 • 97 citations

Isolation of a 45-kDa Fragment from the Kinesin Heavy Chain with Enhanced ATPase and Microtubule-binding Activities

1989 • 96 citations

Characterization of Microtubule Binding Domains in the Arabidopsis Kinesin-like Calmodulin Binding Protein

1998 • 95 citations

Microtubule-based Endoplasmic Reticulum Motility inXenopus laevis: Activation of Membrane-associated Kinesin during Development

1999 • 95 citations

Regulation of Class I and Class II Myosins by Heavy Chain Phosphorylation

1996 • 95 citations

The Rho-GEF Rom2p Localizes to Sites of Polarized Cell Growth and Participates in Cytoskeletal Functions inSaccharomyces cerevisiae

1997 • 95 citations

A plant kinesin heavy chain‐like protein is a calmodulin‐binding protein

1996 • 95 citations

Microtubule-associated Proteins Regulate Microtubule Function as the Track for Intracellular Membrane Organelle Transports.

1996 • 94 citations

The 95F unconventional myosin is required for proper organization of the Drosophila syncytial blastoderm.

1995 • 93 citations

Membrane motors

1999 • 93 citations

Multiple unconventional myosin domains of the intestinal brush border cytoskeleton

1994 • 93 citations

Tctex2-Related Outer Arm Dynein Light Chain Is Phosphorylated at Activation of Sperm Motility

1999 • 92 citations

Dynein Intermediate Chain Mediated Dynein–Dynactin Interaction Is Required for Interphase Microtubule Organization and Centrosome Replication and Separation inDictyostelium

1999 • 91 citations

TheChlamydomonas IDA7Locus Encodes a 140-kDa Dynein Intermediate Chain Required to Assemble the I1 Inner Arm Complex

1998 • 90 citations

Cloning and characterization of myr 6, an unconventional myosin of the dilute/myosin-V family.

1996 • 90 citations

Regulation of kinesin activity by phosphorylation of kinesin-associated proteins.

1994 • 90 citations

Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments

1999 • 90 citations

The Kinesin-like Motor Protein KIF1C Occurs in Intact Cells as a Dimer and Associates with Proteins of the 14-3-3 Family

1999 • 89 citations

Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family.

1989 • 89 citations

Differential Expression and Phosphorylation of the 74-kDa Intermediate Chains of Cytoplasmic Dynein in Cultured Neurons and Glia

1996 • 88 citations

Cytoplasmic dynein undergoes intracellular redistribution concomitant with phosphorylation of the heavy chain in response to serum starvation and okadaic acid.

1994 • 88 citations

Differential regulation of skeletal muscle myosin‐II and brush border myosin‐I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms

1994 • 88 citations

Cloning and Characterization of a Dictyostelium Myosin I Heavy Chain Kinase Activated by Cdc42 and Rac

1996 • 88 citations

Calcium-calmodulin and regulation of brush border myosin-I MgATPase and mechanochemistry

1993 • 86 citations

The “8-kD” Cytoplasmic Dynein Light Chain Is Required for Nuclear Migration and for Dynein Heavy Chain Localization in Aspergillus nidulans

1998 • 86 citations

Overexpression of MAP4 inhibits organelle motility and trafficking in vivo

1997 • 85 citations

Microtubule-associated proteins and microtubule-based translocators have different binding sites on tubulin molecule.

1990 • 85 citations

Real-Time Imaging of the Axonal Transport of Granules Containing a Tissue Plasminogen Activator/Green Fluorescent Protein Hybrid

1998 • 85 citations

Brain Myosin-V, a Calmodulin-carrying Myosin, Binds to Calmodulin-dependent Protein Kinase II and Activates Its Kinase Activity

1999 • 83 citations

Identification and molecular characterization of a yeast myosin I

1995 • 82 citations

Reassociation of microvillar core proteins: making a microvillar core in vitro.

1989 • 82 citations

Regulation of flagellar dynein by an axonemal type-1 phosphatase in Chlamydomonas

1996 • 80 citations

Characterization of DLC-A and DLC-B, two families of cytoplasmic dynein light chain subunits.

1994 • 80 citations

The Tail of a Yeast Class V Myosin, Myo2p, Functions as a Localization Domain

1999 • 79 citations

Interaction of p59fyn Kinase with the Dynein Light Chain, Tctex-1, and Colocalization During Cytokinesis

1998 • 79 citations

Molecular analysis of a cytoplasmic dynein light intermediate chain reveals homology to a family of ATPases

1995 • 78 citations

A Kinesin-like Protein Is Required for Germ Plasm Aggregation in Xenopus

1996 • 77 citations

Characterization of α2β2 and α2 forms of kinesin

1991 • 77 citations

Molecular motors, membrane movements and physiology: emerging roles for myosins

1995 • 76 citations

Interaction of the Rho Family Small G Proteins with Kinectin, an Anchoring Protein of Kinesin Motor

1996 • 76 citations

ida4-1, ida4-2, and ida4-3 are intron splicing mutations affecting the locus encoding p28, a light chain of Chlamydomonas axonemal inner dynein arms.

1995 • 74 citations

Localization of Tctex-1, a Cytoplasmic Dynein Light Chain, to the Golgi Apparatus and Evidence for Dynein Complex Heterogeneity

1998 • 73 citations

Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family.

1993 • 73 citations

Motoring to the Finish: Kinesin and Dynein Work Together to Orient the Yeast Mitotic Spindle

1997 • 72 citations

The kar3p and kip2p motors function antagonistically at the spindle poles to influence cytoplasmic microtubule numbers

1998 • 72 citations

Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton

1999 • 71 citations

Motile Properties of the Kinesin-related Cin8p Spindle Motor Extracted from Saccharomyces cerevisiae Cells

1999 • 71 citations

Smy1p, a Kinesin-related Protein That Does Not Require Microtubules

1998 • 70 citations

SMAP, an Smg GDS-associating Protein Having Arm Repeats and Phosphorylated by Src Tyrosine Kinase

1996 • 69 citations

Budding roles for myosin II on the Golgi

1998 • 69 citations

Arf proteins bind to mitotic kinesin-like protein 1 (MKLP1) in a GTP-dependent fashion

1999 • 69 citations

Cytoplasmic Dynein Intermediate-Chain Isoforms with Different Targeting Properties Created by Tissue-Specific Alternative Splicing

1998 • 68 citations

Ca2+/calmodulin regulation of theArabidopsis kinesin-like calmodulin-binding protein

1998 • 68 citations

Mapmodulin, Cytoplasmic Dynein, and Microtubules Enhance the Transport of Mannose 6-Phosphate Receptors from Endosomes to theTrans-Golgi Network

1999 • 67 citations

Purification and characterization of a myosin I heavy chain kinase from Acanthamoeba castellanii.

1983 • 67 citations

Regulation of 22S dynein by a 29-kD light chain.

1994 • 66 citations

Unconventional Myosins: Anchors in the Membrane Traffic Relay

2000 • 65 citations

A novel cytoplasmic dynein heavy chain: expression of DHC1b in mammalian ciliated epithelial cells

1996 • 64 citations

A novel kinesin-like protein with a calmodulin-binding domain

1996 • 63 citations

Dynein and dynein-related genes

1998 • 63 citations

Casein Kinase II Binds to and Phosphorylates Cytoplasmic Dynein

1997 • 63 citations

Mutations in the bimC box of Cut7 indicate divergence of regulation within the bimC family of kinesin related proteins

1998 • 62 citations

Myosin I heavy-chain genes of Acanthamoeba castellanii: cloning of a second gene and evidence for the existence of a third isoform

1989 • 62 citations

The ATPase Activity of Myr3, a Rat Myosin I, Is Allosterically Inhibited by Its Own Tail Domain and by Ca2+ Binding to Its Light Chain Calmodulin

1998 • 62 citations

Distinct functions of calmodulin are required for the uptake step of receptor-mediated endocytosis in yeast: the type I myosin Myo5p is one of the calmodulin targets

1998 • 61 citations

Minus end-directed kinesin-like motor protein, kcbp, localizes to anaphase spindle poles inHaemanthus endosperm

1998 • 60 citations

Quantification and localization of phosphorylated myosin I isoforms in Acanthamoeba castellanii.

1995 • 59 citations

The Kinesin-related Protein Kip1p of Saccharomyces cerevisiae Is Bipolar

1999 • 57 citations

Purification and characterization of a third isoform of myosin I from Acanthamoeba castellanii

1989 • 57 citations

Microtubules and Microtubule Motors: Mechanisms of Regulation

1996 • 56 citations

A Chromatin-associated Kinesin-related Protein Required for Normal Mitotic Chromosome Segregation in Drosophila

1997 • 56 citations

Mitotic Phosphorylation of the Dynein Light Intermediate Chain is Mediated by cdc2 Kinase

2000 • 55 citations

Disassembly of actin filaments leads to increased rate and frequency of mitochondrial movement along microtubules

1998 • 55 citations

Mapmodulin: A possible modulator of the interaction of microtubule-associated proteins with microtubules

1997 • 55 citations

The Molecular Cloning and Characterization of Drosophila melanogaster Myosin-IA and Myosin-IB

1994 • 55 citations

GTP gamma S inhibits organelle transport along axonal microtubules.

1993 • 54 citations

Calmodulin‐Binding Proteins and Calcium/Calmodulin Regulated Enzyme Activities Associated with Brain Actomyosin

1990 • 54 citations

Acanthamoeba myosin I heavy chain kinase is activated by phosphatidylserine-enhanced phosphorylation.

1990 • 53 citations

Regulation of dynein‐driven motility in cilia and flagella

1994 • 52 citations

KLP38B: A Mitotic Kinesin-related Protein That Binds PP1

1997 • 52 citations

Phosphorylation and Cytoskeletal Anchoring of the Acetylcholine Receptor by Src Class Protein-tyrosine Kinases

1999 • 52 citations

A high molecular mass non-muscle tropomyosin isoform stimulates retrograde organelle transport

1996 • 50 citations

Interspecies conservation of outer arm dynein intermediate chain sequences defines two intermediate chain subclasses.

1995 • 49 citations

A second isoform of chicken brush border myosin I contains a 29‐residue inserted sequence that binds calmodulin

1990 • 49 citations

Particles move along actin filament bundles in nerve growth cones.

1995 • 48 citations

ADrosophilaKinesin-like Protein, Klp38B, Functions during Meiosis, Mitosis, and Segmentation

1997 • 48 citations

Purification and Characterization of a Dictyostelium Protein Kinase Required for Actin Activation of the Mg2+ATPase Activity of Dictyostelium Myosin ID

1995 • 47 citations

Nonuniform Microtubular Polarity Established by CHO1/MKLP1 Motor Protein Is Necessary for Process Formation of Podocytes

1998 • 46 citations

The bop2-1 mutation reveals radial asymmetry in the inner dynein arm region of Chlamydomonas reinhardtii.

1994 • 46 citations

Interaction of the CD5 cytoplasmic domain with the Ca2+ /calmodulin-dependent kinase IIδ

1998 • 46 citations

Phosphotransferases Associated with the Regulation of Kinesin Motor Activity

1997 • 45 citations

Gene Knockouts Reveal Separate Functions for Two Cytoplasmic Dyneins inTetrahymena thermophila

1999 • 44 citations

Microtubule-based motor function in mitosis

1999 • 43 citations

Kinesin and tau bind to distinct sites on microtubules

1994 • 42 citations

Identification of Flagellar Proteins That Initiate the Activation of Sperm Motilityin Vivo

1998 • 42 citations

Myosin I heavy chain kinase: Cloning of the full-length gene and acidic lipid-dependent activation by Rac and Cdc42

1999 • 42 citations

In vitro motility from recombinant dynein heavy chain.

1996 • 41 citations

Riding the polar winds: Chromosomes motor down East

1995 • 41 citations

Increased protein phosphorylation of cytoplasmic dynein results in impaired motor function

1999 • 39 citations

A Microtubule-associated Protein (MAP2) Kinase Restores Microtubule Motility in Embryonic Brain

1995 • 39 citations

Localization of motor-related proteins and associated complexes to active, but not inactive, centromeres

1998 • 38 citations

Effect of MAP2, MAP2c, and tau on kinesin-dependent microtubule motility

1991 • 37 citations

Molecular cloning of Fyn-associated molecules in the mouse central nervous system

1997 • 36 citations

Identification of kinesin-C, a calmodulin-binding carboxy-terminal kinesin in animal ( Strongylocentrotus purpuratus ) cells 1 1Edited by A. R. Fersht

1999 • 35 citations

Novel 130‐kDa rat liver myosin‐1 will translocate actin filaments

1994 • 35 citations

M Phase Phosphorylation of Cytoplasmic Dynein Intermediate Chain and p150Glued

1999 • 33 citations

Changes in kinesin distribution and phosphorylation occur during regulated secretion in pancreatic acinar cells

1998 • 32 citations

Motors Driving mRNA Localization

1998 • 31 citations

In Vitro Reconstitution of Microtubule Plus End-directed, GTPγS-sensitive Motility ofGolgi Membranes

1998 • 31 citations

Microtubule‐associated movement of mitochondria and small particles in Acanthamoeba castellanii

1995 • 30 citations

Zipper Protein, a B-G Protein with the Ability to Regulate Actin/Myosin 1 Interactions in the Intestinal Brush Border

1996 • 29 citations

Dynactin Phosphorylation Is Modulated in Response to Cellular Effectors

1997 • 24 citations

Chromosome movement: Kinetochores motor along

1998 • 24 citations

Molecular characterization of myosin V from Drosophila melanogaster.

1998 • 21 citations

Immunolocalization of myosin I heavy chain kinase in Acanthamoeba castellanii and binding of purified kinase to isolated plasma membranes.

1991 • 20 citations

Identification of a dynein molecular motor component in Torpedo electroplax; binding and phosphorylation of Tctex‐1 by Fyn¹

1998 • 20 citations

All-trans-Retinoic Acid-mediated Growth Inhibition Involves Inhibition of Human Kinesin-related Protein HsEg5

1999 • 19 citations

Tau proteins bind to kinesin and modulate its activation by microtubules.

1996 • 19 citations

BimC motor protein KLP61F cycles between mitotic spindles and fusomes in Drosophila germ cells

1999 • 19 citations

Mapping of the microvillar 110K-calmodulin complex (brush border myosin I). Identification of fragments containing the catalytic and F-actin-binding sites and demonstration of a calcium ion-dependent conformational change

1990 • 16 citations

Identification and Characterization in Xenopus of XsmgGDS, a RalB Binding Protein

1998 • 15 citations

A staufen-like RNA-binding protein in translocation channels linking nurse cells to oocytes in Notonecta shows nucleotide-dependent attachment to microtubules

1999 • 14 citations

The dilute-lethal (dl) gene attacks a Ca2+ store in the dendritic spine of Purkinje cells in mice

1996 • 13 citations

Poly(A) mRNA is attached to insect ovarian microtubules in vivo in a nucleotide-sensitive manner

1999 • 12 citations

Recombinant expression of the brush border myosin I heavy chain

1995 • 11 citations

Functional and molecular diversity of dynein heavy chains

1996 • 11 citations

Cell cycle regulation of organelle transport

1997 • 7 citations

Increased protein phosphorylation of cytoplasmic dynein results in impaired motor function

1999 • 6 citations

Kinesin Activation Drives the Retrieval of Secretory Membranes Following Secretion in Rabbit Lacrimal Acinar Cells

1998 • 3 citations

Differential phosphorylation in vivo of cytoplasmic dynein in anterograde and whole cell compartments.

1995 • 3 citations