Plk Is an M-Phase-Specific Protein Kinase and Interacts with a Kinesin-Like Protein, CHO1/MKLP-1

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

ANIMAL CELL CYCLES AND THEIR CONTROL

1992 • 1,239 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

1992 • 936 citations

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.

1991 • 858 citations

A one-step purification of membrane proteins using a high efficiency immunomatrix.

1982 • 782 citations

Monoclonal antibodies to mitotic cells.

1983 • 609 citations

Polo, a mitotic mutant of Drosophila displaying abnormal spindle poles

1988 • 546 citations

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

1995 • 471 citations

Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs

1990 • 446 citations

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1989 • 439 citations

In vitro effects on microtubule dynamics of purified Xenopus M phase-activated MAP kinase

1991 • 422 citations

polo encodes a protein kinase homolog required for mitosis in Drosophila.

1991 • 403 citations

A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts

1994 • 402 citations

CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase.

1991 • 384 citations

p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.

1989 • 376 citations

A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles

1992 • 356 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

MAP Kinase Becomes Stably Activated at Metaphase and Is Associated with Microtubule-Organizing Centers during Meiotic Maturation of Mouse Oocytes

1993 • 300 citations

Induction and down-regulation of PLK, a humanserine/threonine kinase expressed in proliferating cells andtumors.

1994 • 278 citations

Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5

1994 • 275 citations

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.

1991 • 274 citations

Relocation and distinct subcellular localization of p34cdc2-cyclin B complex at meiosis reinitiation in starfish oocytes.

1992 • 271 citations

A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.

1993 • 270 citations

Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope.

1994 • 257 citations

Phosphoproteins are components of mitotic microtubule organizing centers.

1984 • 246 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Xklp15 a chromosomal xenopus kinesin-like protein essential for spindle organization and chromosome positioning

1995 • 237 citations

cdc2 Gene Expression at the G ₁ to S Transition in Human T Lymphocytes

1990 • 220 citations

Cytoplasmic accumulation of cyclin B1 in human cells: Association with a detergent-resistant compartment and with the centrosome

1992 • 211 citations

Chromosomal passengers: Toward an integrated view of mitosis

1991 • 198 citations

Phosphorylation of myosin-II regulatory light chain by cyclin-p34cdc2: a mechanism for the timing of cytokinesis.

1992 • 197 citations

Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein

1988 • 189 citations

Identification of an Early-Growth-Response Gene Encoding a Novel Putative Protein Kinase

1992 • 187 citations

Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.

1993 • 158 citations

The phosphorylation of kinesin regulates its binding to synaptic vesicles.

1992 • 156 citations

Mitosis

1989 • 155 citations

In vivo phosphorylation of regulatory light chain of myosin II during mitosis of cultured cells

1994 • 154 citations

Distribution of a matrix component of the midbody during the cell cycle in Chinese hamster ovary cells

1988 • 150 citations

Mitotic Regulation of Microtubule Cross-Linking Activity of CENP-E Kinetochore Protein

1994 • 148 citations

A conserved mitotic kinase active at late anaphase—telophase in syncytial Drosophila embryos

1993 • 128 citations

Proteins of the mammalian mitotic spindle: phosphorylation/dephosphorylation of MAP-4 during mitosis

1991 • 121 citations

Raf-1 forms a stable complex with Mek1 and activates Mek1 by serine phosphorylation.

1993 • 121 citations

Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase.

1994 • 116 citations

Identification of an early-growth-response gene encoding a novel putative protein kinase.

1992 • 110 citations

A monoclonal antibody to a mitotic microtubule-associated protein blocks mitotic progression.

1990 • 107 citations

Association of p34cdc2/cyclin B complex with microtubules in starfish oocytes

1993 • 87 citations

Cell Cycle- and Terminal Differentiation-Associated Regulation of the Mouse mRNA Encoding a Conserved Mitotic Protein Kinase

1993 • 86 citations

A Multicopy Suppressor Gene of the Saccharomyces cerevisiae G₁ Cell Cycle Mutant Gene dbf4 Encodes a Protein Kinase and Is Identified as CDC5

1993 • 84 citations

At least two kinases phosphorylate the MPM-2 epitope during Xenopus oocyte maturation.

1993 • 79 citations

Heterogeneity and microtubule interaction of the CHO1 antigen, a mitosisspecific kinesin-like protein: Analysis of subdomains expressed in insect sf9 cells

1994 • 61 citations

Cell cycle- and terminal differentiation-associated regulation of the mouse mRNA encoding a conserved mitotic protein kinase.

1993 • 51 citations

A Xenopus Nonmuscle Myosin Heavy Chain Isoform Is Phosphorylated by Cyclin-p34cdc2 Kinase during Meiosis

1995 • 27 citations

Mitosis-specific phosphorylation of myosin light chain kinase.

1991 • 16 citations