Point mutation of adenosine triphosphate-binding motif generated rigor kinesin that selectively blocks anterograde lysosome membrane transport.

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility

1985 • 1,930 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Movement of microtubules by single kinesin molecules

1989 • 878 citations

Cross-linker system between neurofilaments, microtubules and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

1982 • 672 citations

The neuron-specific kinesin superfamily protein KIF1A is a uniqye monomeric motor for anterograde axonal transport of synaptic vesicle precursors

1995 • 646 citations

A novel brain ATPase with properties expected for the fast axonal transport motor

1985 • 604 citations

KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria

1994 • 584 citations

Retrograde transport by the microtubule-associated protein MAP 1C

1987 • 547 citations

KAR3, a kinesin-related gene required for yeast nuclear fusion

1990 • 504 citations

A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor.

1991 • 478 citations

Identification of two lysosomal membrane glycoproteins.

1985 • 475 citations

A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses

1989 • 392 citations

Changes in lysosome shape and distribution correlated with changes in cytoplasmic pH.

1989 • 387 citations

Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.

1990 • 384 citations

Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA.

1989 • 354 citations

KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport.

1995 • 291 citations

Radial extension of macrophage tubular lysosomes supported by kinesin

1990 • 276 citations

Mitochondria are associated with microtubules and not with intermediate filaments in cultured fibroblasts.

1982 • 262 citations

Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

1989 • 261 citations

Kinesin associates with anterogradely transported membranous organelles in vivo.

1991 • 254 citations

Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic [published errata appear in J Cell Biol 1995 Mar;128(5):following 988 and 1995 May;129(3):893]

1995 • 243 citations

KIF3A is a new microtubule-based anterograde motor in the nerve axon.

1994 • 240 citations

Kinesin ATPase: rate-limiting ADP release.

1988 • 238 citations

The C. elegans unc-104 4 gene encodes a putative kinesin heavy chain-like protein

1991 • 220 citations

Identification of a microtubule-based cytoplasmic motor in the nematode C. elegans

1987 • 218 citations

Dominant inhibitory mutations in the Mg(2+)-binding site of RasH prevent its activation by GTP.

1991 • 211 citations

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells

1992 • 193 citations

Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.

1992 • 188 citations

The response of the Golgi complex to microtubule alterations: the roles of metabolic energy and membrane traffic in Golgi complex organization.

1989 • 185 citations

The distribution, abundance and subcellular localization of kinesin.

1989 • 179 citations

KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B.

1995 • 162 citations

A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.

1994 • 160 citations

Kinesin-mediated organelle translocation revealed by specific cellular manipulations.

1994 • 152 citations

Cloning and localization of a conventional kinesin motor expressed exclusively in neurons

1994 • 151 citations

Lectin labeling of sprouting neurons. II. Relative movement and appearance of glycoconjugates during plasmalemmal expansion.

1981 • 139 citations

Effects of Kinesin Mutations on Neuronal Functions

1992 • 117 citations

The carboxyl-terminal domain of kinesin heavy chain is important for membrane binding.

1994 • 110 citations

Competition between motor molecules (kinesin and cytoplasmic dynein) and fibrous microtubule-associated proteins in binding to microtubules.

1994 • 109 citations

The kinesin superfamily: tails of functional redundancy

1991 • 103 citations

Axonal transport and the cytoskeleton

1993 • 97 citations

Organization of cortical cytoskeleton of cultured chromaffin cells and involvement in secretion as revealed by quick-freeze, deep-etching, and double-label immunoelectron microscopy

1992 • 91 citations

A Collection of cDNA Clones with Specific Expression Patterns in Mouse Brain

1990 • 86 citations

Association of kinesin with the Golgi apparatus in rat hepatocytes

1994 • 83 citations

Immunolocalization of kinesin in sea urchin coelomocytes: Association of kinesin with intracellular organelles

1992 • 79 citations

Characterization of α2β2 and α2 forms of kinesin

1991 • 77 citations

Spatial segregation of the regulated and constitutive secretory pathways.

1989 • 74 citations

The lethal(1)TW-6cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-binding domain.

1991 • 70 citations

Dominant Inhibitory Mutations in the Mg²⁺-Binding Site of Ras^H Prevent Its Activation by GTP

1991 • 68 citations

Characterization of the KLP68D kinesin-like protein in Drosophila: possible roles in axonal transport.

1994 • 68 citations

Dihydrotetramethylrosamine: A long wavelength, fluorogenic peroxidase substrate evaluated in vitro and in a model phagocyte

1991 • 52 citations

Localization of dynamin: Widespread distribution in mature neurons and association with membranous organelles

1993 • 38 citations

A mutation in the putative Mg(2+)-binding site of Gs alpha prevents its activation by receptors.

1991 • 23 citations

Thermal drift is enough to drive a single microtubule along its axis even in the absence of motor proteins

1993 • 21 citations

KIF2 is a new anterograde microtubule based motor which transports membranous organelles distinct from those carried by KHC or KIF3A/B

1994 • 6 citations

A Mutation in the Putative Mg²⁺-Binding Site of G_s α Prevents Its Activation by Receptors

1991 • 6 citations