Rho as a regulator of the cytoskeleton

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Focal Adhesions: Transmembrane Junctions Between the Extracellular Matrix and the Cytoskeleton

1988 • 2,137 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

The Cellular Functions of Small GTP-Binding Proteins

1990 • 881 citations

ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons.

1994 • 790 citations

Regulation of inositol phospholipid-specific phospholipase C isozymes.

1992 • 740 citations

Asparagine residue in the rho Gene Product Is the Modification Site for Botulinum ADP-ribosyltransferase

1989 • 550 citations

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

1989 • 529 citations

Small GTP-Binding Proteins

1992 • 526 citations

Phosphoinositides and Calcium as Regulators of Cellular Actin Assembly and Disassembly

1994 • 524 citations

A novel ras-related gene family

1985 • 487 citations

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.

1994 • 469 citations

Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.

1992 • 458 citations

Function of Ras as a molecular switch in signal transduction.

1992 • 425 citations

Intracellular localization of the P21rho proteins.

1992 • 382 citations

Friends and family: The role of the rab GTPases in vesicular traffic

1993 • 364 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

1993 • 363 citations

Protein Prenylation: a Mediator of Protein-Protein Interactions

1993 • 346 citations

Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus

1992 • 343 citations

Development of cell polarity in budding yeast

1991 • 252 citations

Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.

1994 • 245 citations

Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae.

1994 • 242 citations

Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.

1993 • 211 citations

Involvement of rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in cell motility.

1993 • 200 citations

Submembranous junctional plaque proteins include potential tumor suppressor molecules.

1993 • 179 citations

Substrate for botulinum ADP-ribosyltransferase, Gb, has an amino acid sequence homologous to a putative rho gene product.

1988 • 178 citations

rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells.

1994 • 171 citations

Actin-binding proteins

1990 • 164 citations

Botulinum ADP‐ribosyltransferase C3

1988 • 162 citations

Nucleotide sequence of human rho cDNA clone 12

1987 • 143 citations

Purification of the 22 kDa protein substrate of botulinum ADP‐ribosyltransferase C3 from porcine brain cytosol and its characterization as a GTP‐binding protein highly homologous to the rho gene product

1989 • 139 citations

Coding sequence of humanrhocDNAs clone 6 and clone 9

1988 • 137 citations

ADP-ribosylation of the bovine brain rho protein by botulinum toxin type C1.

1988 • 126 citations

Regulation of morphology by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI) in Swiss 3T3 cells.

1993 • 123 citations

Guanine-nucleotide exchange factors: a family of positive regulators of Ras and related GTPases

1994 • 104 citations

Different structural organization of Ras and Rho effector domains.

1993 • 83 citations

The posttranslationally modified C-terminal structure of bovine aortic smooth muscle rhoA p21

1991 • 74 citations