Myosin I heavy chain kinase: Cloning of the full-length gene and acidic lipid-dependent activation by Rac and Cdc42
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References (46)
Molecular cloning: A laboratory manual
1990 • 85,659 citations
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1994 • 1,520 citations
Structural basis for the binding of proline-rich peptides to SH3 domains
1994 • 1,016 citations
Modular binding domains in signal transduction proteins
1995 • 962 citations
Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization
1996 • 873 citations
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
1997 • 687 citations
A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases
1995 • 625 citations
Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes
1997 • 560 citations
Synapsins: Mosaics of Shared and Individual Domains in a Family of Synaptic Vesicle Phosphoproteins
1989 • 535 citations
Calmodulin-binding domains: just two faced or multi-faceted?
1995 • 368 citations
A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.
1995 • 365 citations
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins
1990 • 352 citations
A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1
1998 • 325 citations
Regulation of Phosphorylation Pathways by p21 GTPases
1996 • 300 citations
Emerging from the Pak: the p21-activated protein kinase family
1997 • 285 citations
MYOSIN-I
1991 • 252 citations
Molecular Cloning of a New Member of the p21-Cdc42/Rac-activated Kinase (PAK) Family
1995 • 240 citations
A GTPase-independent Mechanism of p21-activated Kinase Activation
1998 • 204 citations
The p21Rac/Cdc42-activated kinases (PAKs)
1998 • 190 citations
Molecular Characterization of Ste20p, a Potential Mitogen-activated Protein or Extracellular Signal-regulated Kinase Kinase (MEK) Kinase Kinase from Saccharomyces cerevisiae
1995 • 174 citations
Delineation of the Cdc42/Rac-Binding Domain of p21-Activated Kinase
1998 • 139 citations
Acanthamoeba Myosin
1973 • 126 citations
Acanthamoeba cofactor protein is a heavy chain kinase required for actin activation of the Mg2+-ATPase activity of Acanthamoeba myosin I
1977 • 126 citations
Activation of Myosin-I by Members of the Ste20p Protein Kinase Family
1996 • 100 citations
Regulation of Class I and Class II Myosins by Heavy Chain Phosphorylation
1996 • 95 citations
Cloning and Characterization of a Dictyostelium Myosin I Heavy Chain Kinase Activated by Cdc42 and Rac
1996 • 88 citations
The localization and sequence of the phosphorylation sites of Acanthamoeba myosins I
1989 • 85 citations
Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation
1995 • 80 citations
p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I
1997 • 79 citations
Molecular Cloning and Sequencing of the Cytostatic G Protein-activated Protein Kinase PAK I
1996 • 77 citations
Novel myosins
1991 • 69 citations
Myosin I heavy-chain genes of Acanthamoeba castellanii: cloning of a second gene and evidence for the existence of a third isoform
1989 • 62 citations
Identification of the regulatory autophosphorylation site of autophosphorylation-dependent protein kinase (auto-kinase)
1998 • 58 citations
Purification and characterization of a third isoform of myosin I from Acanthamoeba castellanii
1989 • 57 citations
The Catalytic Domain of Acanthamoeba Myosin I Heavy Chain Kinase
1996 • 56 citations
Acanthamoeba myosin I heavy chain kinase is activated by phosphatidylserine-enhanced phosphorylation.
1990 • 53 citations
Substrate specificity of Acanthamoeba myosin I heavy chain kinase as determined with synthetic peptides.
1990 • 47 citations
Regulation of the p21-activated Kinase-relatedDictyostelium Myosin I Heavy Chain Kinase by Autophosphorylation, Acidic Phospholipids, and Ca2+-Calmodulin
1998 • 34 citations
[2] Purification of myosin I and myosin I heavy chain kinase from Acanthamoeba castellanii
1991 • 29 citations
Identification by mass spectrometry of the phosphorylated residue responsible for activation of the catalytic domain of myosin I heavy chain kinase, a member of the PAK/STE20 family
1997 • 25 citations
The Catalytic Domain of Acanthamoeba Myosin I Heavy Chain Kinase
1996 • 24 citations
Inhibition of Acanthamoeba myosin I heavy chain kinase by Ca(2+)-calmodulin.
1992 • 22 citations
Effect of mutating the regulatory phosphoserine and conserved threonine on the activity of the expressed catalytic domain of Acanthamoeba myosin I heavy chain kinase
1998 • 22 citations
Properties of Acanthamoeba Myosin I Heavy Chain Kinase Bound to Phospholipid Vesicles
1995 • 14 citations
Preparation of a phospholipid-insensitive, autophosphorylation-activated catalytic fragment of Acanthamoeba myosin I heavy chain kinase.
1992 • 12 citations
Autophosphorylation-independent activation of Acanthamoeba myosin I heavy chain kinase by plasma membranes.
1993 • 12 citations