Casein kinase II is a predominantly nuclear enzyme.
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References (75)
Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
1986 • 6,284 citations
IκB: a Specific Inhibitor of the NF-κB Transcription Factor
1988 • 2,203 citations
Protein structure: A practical approach
1990 • 2,071 citations
PROTEIN SERINE/THREONINE KINASES
1987 • 1,457 citations
Vectors for selective expression of cloned DNAs by T7 RNA polymerase
1987 • 1,449 citations
Casein kinase 2: An ‘eminence grise’ in cellular regulation?
1990 • 920 citations
Casein Kinases—Multipotential Protein Kinases
1982 • 454 citations
The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells
1989 • 439 citations
Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites.
1991 • 439 citations
Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region
1987 • 426 citations
p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase.
1989 • 376 citations
Isolation, sequencing, and disruption of the yeast CKA2 gene: casein kinase II is essential for viability in Saccharomyces cerevisiae.
1990 • 365 citations
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 • 355 citations
Casein kinase I and II--multipotential serine protein kinases: structure, function, and regulation.
1991 • 340 citations
The region of the HPV E7 oncoprotein homologous to adenovirus E1a and Sv40 large T antigen contains separate domains for Rb binding and casein kinase II phosphorylation.
1990 • 323 citations
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates.
1991 • 318 citations
Activation of casein kinase II in response to insulin and to epidermal growth factor.
1987 • 299 citations
Myc oncoproteins are phosphorylated by casein kinase II.
1989 • 287 citations
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.
1990 • 277 citations
Cyclic-AMP-dependent protein kinase type II is associated with the Golgi complex and with centrosomes
1985 • 234 citations
Casein kinase II is elevated in solid human tumours and rapidly proliferating non‐neoplastic tissue
1990 • 211 citations
Insulin-like growth factor I and insulin rapidly increase casein kinase II activity in BALB/c 3T3 fibroblasts.
1988 • 207 citations
A synthetic peptide substrate specific for casein kinase II.
1985 • 202 citations
Isolation and characterization of recombinant human casein kinase II subunits α and β from bacteria
1991 • 197 citations
Serum-stimulated cell growth causes oscillations in casein kinase II activity
1989 • 171 citations
Isolation and sequencing of cDNA clones encoding alpha and beta subunits of Drosophila melanogaster casein kinase II.
1987 • 164 citations
Intracellular localization of human DNA polymerase alpha with monoclonal antibodies.
1982 • 161 citations
Isolation and characterization of human cDNA clones encoding the .alpha. and the .alpha.' subunits of casein kinase II
1990 • 160 citations
A casein kinase II-related activity is involved in phosphorylation of microtubule-associated protein MAP-1B during neuroblastoma cell differentiation.
1988 • 153 citations
Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases.
1984 • 153 citations
Regulation of casein kinase II activity by epidermal growth factor in human A-431 carcinoma cells
1989 • 147 citations
Synthetic peptides including acidic clusters as substrates and inhibitors of rat liver casein kinase TS (type-2).
1984 • 137 citations
The nuclear lamin protein family in higher vertebrates. Identification of quantitatively minor lamin proteins by monoclonal antibodies.
1986 • 134 citations
Casein Kinase II as a Potentially Important Enzyme Concerned with Signal Transduction
1988 • 128 citations
Immunocytochemical localization of casein kinase II during interphase and mitosis.
1991 • 122 citations
Isolation, Sequencing, and Disruption of the CKA1 Gene Encoding the Alpha Subunit of Yeast Casein Kinase II
1988 • 118 citations
Tubulin phosphorylation by casein kinase II is similar to that found in vivo.
1987 • 116 citations
Protein kinase NII and the regulation of rDNA transcription in mammalian cells
1989 • 115 citations
Induction of casein kinase II during differentiation of 3T3-L1 cells.
1987 • 113 citations
Casein kinase II from Caenorhabditis elegans. Properties and developmental regulation of the enzyme; cloning and sequence analyses of cDNA and the gene for the catalytic subunit.
1990 • 109 citations
Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells.
1990 • 109 citations
Molecular cloning of the human casein kinase II .alpha. subunit
1989 • 108 citations
Cytoskeletal control of centrioles movement during the establishment of polarity in Madin-Darby canine kidney cells.
1990 • 105 citations
Structure and developmental expression of the chicken CDC2 kinase.
1989 • 103 citations
In Vitro phosphorylation of SV40 large T antigen
1988 • 103 citations
Characterization of the catalytic subunit of casein kinase II expressed in Escherichia coli and regulation of activity.
1991 • 99 citations
Casein kinase II of yeast contains two distinct alpha polypeptides and an unusually large beta subunit.
1987 • 98 citations
Casein kinase II. cDNA sequences, developmental expression, and tissue distribution of mRNAs for alpha, alpha', and beta subunits of the chicken enzyme
1991 • 98 citations
Negative charge at the casein kinase II phosphorylation site is important for transformation but not for Rb protein binding by the E7 protein of human papillomavirus type 16.
1991 • 97 citations
The E7 protein of human papillomavirus type 16 is phosphorylated by casein kinase II.
1989 • 97 citations
Enhanced casein kinase II activity in human tumour cell cultures
1984 • 94 citations
Mechanisms of Signal Transduction to the Cell Nucleus
1990 • 85 citations
Human phosvitin/casein kinase type II. Molecular cloning and sequencing of full-length cDNA encoding subunit beta
1989 • 85 citations
Cytoplasmic and nuclear distribution of casein kinase II: characterization of the enzyme uptake by bovine adrenocortical nuclear preparation
1990 • 84 citations
The c-erbA alpha-encoded thyroid hormone receptor is phosphorylated in its amino terminal domain by casein kinase II.
1989 • 83 citations
Isolation, Sequencing, and Disruption of the Yeast CKA2 Gene: Casein Kinase II Is Essential for Viability in Saccharomyces cerevisiae
1990 • 79 citations
Nuclear Function and Organization: The Potential of Immunochemical Approaches
1988 • 79 citations
Synthetic peptide substrates for casein kinase 2. Assessment of minimum structural requirements for phosphorylation
1988 • 74 citations
Association of casein kinase II with microtubules
1989 • 70 citations
Casein kinase II accumulation in the nucleolus and its role in nucleolar phosphorylation
1988 • 70 citations
Protein Serine Threonine Kinases
1987 • 63 citations
Regulating Cell Growth: Casein-kinase-II-dependent Phosphorylation of Nuclear Oncoproteins
1988 • 63 citations
Cloning and characterization of a cDNA encoding the .beta. subunit of human casein kinase II
1989 • 57 citations
A somatic cell-derived system for studying both early and late mitotic events in vitro
1989 • 54 citations
Isolation of a transplantable cell line induced by the MC29 avian leukosis virus.
1974 • 53 citations
Glycogen synthase (casein) kinase-1: tissue distribution and subcellular localization
1985 • 52 citations
Casein kinase II from Rana temporaria oocytes
1989 • 48 citations
Properties of rat liver nuclear protein kinases
1979 • 43 citations
Isolation and Sequencing of cDNA Clones Encoding Alpha and Beta Subunits of Drosophila melanogaster Casein Kinase II
1987 • 39 citations
Heterogeneous binding of high mobility group chromosomal proteins to nuclei
1981 • 28 citations
Independent quantitation of the mitochondrial and the cytosolic isoenzyme of aspartate aminotransferase in chicken tissues by radioimmunoassays.
1981 • 25 citations
The β subunit of casein kinase II: cloning of cDNAs from murine and porcine origin and expression of the porcine sequence as a fusion protein
1991 • 23 citations
The nucleotide sequence of the mouse cDNA encoding the beta subunit of casein kinase II
1990 • 21 citations
Thyrotropin-Releasing Hormone
1978 • 9 citations
Signal Transduction to the Cell Nucleus
1992 • 8 citations
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