MAPs, MARKs and microtubule dynamics

Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport

1998 • 1,634 citations

Active and Inactive Protein Kinases: Structural Basis for Regulation

1996 • 1,361 citations

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

1992 • 936 citations

MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption

1997 • 836 citations

Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

1993 • 759 citations

Domains of tau Protein and Interactions with Microtubules

1994 • 630 citations

Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons

1992 • 569 citations

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau

1994 • 561 citations

Identification of katanin, an ATPase that severs and disassembles stable microtubules

1993 • 490 citations

Tubulin dynamics in cultured mammalian cells.

1984 • 489 citations

Microtubules and microtubule-associated proteins

1995 • 465 citations

The abnormal phosphorylation of tau protein at Ser-202 in Alzheimer disease recapitulates phosphorylation during development.

1993 • 439 citations

Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain.

1992 • 415 citations

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

1996 • 397 citations

Mitotic mechanisms in Alzheimer's disease?

1996 • 384 citations

Basolateral sorting of LDL receptor in MDCK cells: The cytoplasmic domain contains two tyrosine-dependent targeting determinants

1992 • 366 citations

Microtubule-associated Protein/Microtubule Affinity-regulating Kinase (p110mark)

1995 • 361 citations

Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau

1995 • 345 citations

Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules.

1995 • 317 citations

Sequential phosphorylation of Tau by glycogen synthase kinase‐3β and protein kinase A at Thr212 and Ser214 generates the Alzheimer‐specific epitope of antibody AT100 and requires a paired‐helical‐filament‐like conformation

1998 • 308 citations

Tau domains, phosphorylation, and interactions with microtubules

1995 • 299 citations

Morphogenetic Properties of Microtubules and Mitotic Spindle Assembly

1996 • 292 citations

The Pathogenesis of Alzheimer Disease: An Alternative to the Amyloid Hypothesis

1996 • 288 citations

Inhibition of MAP2 expression affects both morphological and cell division phenotypes of neuronal differentiation

1991 • 207 citations

Phosphorylation of Microtubule-associated Proteins MAP2 and MAP4 by the Protein Kinase p110mark

1996 • 188 citations

Cytoskeletal proteins and Golgi dynamics

1998 • 180 citations

Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity

1997 • 168 citations

Cytoskeletal Plasticity in Cells Expressing Neuronal Microtubule-Associated Proteins

1996 • 162 citations

Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo

1996 • 149 citations

An analysis of the role of microfilaments in the establishment and maintenance of asymmetry in Caenorhabditis elegans zygotes

1988 • 131 citations

Diverse Distribution and Function of Fibrous Microtubule-Associated Proteins in the Nervous System

1994 • 124 citations

Kinesin-Related Proteins at Mitotic Spindle Poles: Function and Regulation

1996 • 121 citations

Proteins of the mammalian mitotic spindle: phosphorylation/dephosphorylation of MAP-4 during mitosis

1991 • 121 citations

PTL-1, a microtubule-associated protein with tau-like repeats from the nematode Caenorhabditis elegans

1996 • 114 citations

Microtubules and axonal growth

1997 • 113 citations

Microtubule dynamics: Treadmilling comes around again

1997 • 103 citations

A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe.

1990 • 100 citations

Microtubule-associated Proteins Regulate Microtubule Function as the Track for Intracellular Membrane Organelle Transports.

1996 • 94 citations

Three distinct axonal transport rates for tau, tubulin, and other microtubule-associated proteins: evidence for dynamic interactions of tau with microtubules in vivo

1995 • 92 citations

Overexpression of MAP4 inhibits organelle motility and trafficking in vivo

1997 • 85 citations

Interaction between kinesin, microtubules, and microtubule‐associated protein 2

1989 • 63 citations

Catastrophic revelations about Op18/stathmin

1996 • 62 citations

Microtubule-associated proteins, phosphorylation gradients, and the establishment of neuronal polarity.

1996 • 56 citations

A muscle-specific variant of microtubule-associated protein 4 (MAP4) is required in myogenesis

1996 • 55 citations

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

1996 • 49 citations

Microtubule‐associated protein function: Lessons from expression in spodoptera frugiperda cells

1994 • 43 citations

A Microtubule-associated Protein (MAP2) Kinase Restores Microtubule Motility in Embryonic Brain

1995 • 39 citations

Loss of a Mr 78,000 marker in chemically induced transplantable carcinomas and primary carcinoma of human pancreas.

1988 • 35 citations

MHP1, an essential gene in Saccharomyces cerevisiae required for microtubule function.

1996 • 22 citations

Cell polarity: Par for the polar course

1997 • 20 citations