Dynactin Is Required for Microtubule Anchoring at Centrosomes

Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis.

1996 • 634 citations

Pericentrin, a highly conserved centrosome protein involved in microtubule organization

1994 • 579 citations

A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly

1996 • 565 citations

Distinct populations of microtubules: Tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

1984 • 532 citations

Localization of cytoplasmic dynein to mitotic spindles and kinetochores

1990 • 508 citations

The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium.

1989 • 498 citations

Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus.

1988 • 488 citations

Pericentrin and γ-Tubulin Form a Protein Complex and Are Organized into a Novel Lattice at the Centrosome

1998 • 485 citations

Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein.

1991 • 482 citations

Rhodopsin’s Carboxy-Terminal Cytoplasmic Tail Acts as a Membrane Receptor for Cytoplasmic Dynein by Binding to the Dynein Light Chain Tctex-1

1999 • 478 citations

Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued.

1995 • 466 citations

Cytoplasmic dynein and dynactin in cell division and intracellular transport

1999 • 454 citations

CLIP-170 links endocytic vesicles to microtubules

1992 • 367 citations

Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling.

1996 • 338 citations

Affinity Chromatography Demonstrates a Direct Binding between Cytoplasmic Dynein and the Dynactin Complex

1995 • 338 citations

Spindle Assembly in Xenopus Egg Extracts: Respective Roles of Centrosomes and Microtubule Self-Organization

1997 • 335 citations

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation.

1993 • 335 citations

Two activators of microtubule-based vesicle transport.

1991 • 325 citations

The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1).

1995 • 307 citations

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells.

1995 • 301 citations

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole.

1996 • 301 citations

Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein.

1991 • 300 citations

Ultrastructural analysis of the dynactin complex: an actin-related protein is a component of a filament that resembles F-actin.

1994 • 275 citations

Role of Dynactin in Endocytic Traffic: Effects of Dynamitin Overexpression and Colocalization with CLIP-170

1999 • 273 citations

Microtubule release from the centrosome

1997 • 252 citations

Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells

1998 • 249 citations

NuMA is required for the organization of microtubules into aster-like mitotic arrays.

1995 • 242 citations

Molecular Requirements for Bi-directional Movement of Phagosomes Along Microtubules

1997 • 232 citations

Mitotic Spindle Poles are Organized by Structural and Motor Proteins in Addition to Centrosomes

1997 • 220 citations

Cytoplasmic Dynein and Dynactin Are Required for the Transport of Microtubules into the Axon

1998 • 217 citations

NuMA is required for the proper completion of mitosis.

1993 • 207 citations

The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos

1998 • 195 citations

Polarity and nucleation of microtubules in polarized epithelial cells

1995 • 192 citations

Analysis of Dynactin Subcomplexes Reveals a Novel Actin-Related Protein Associated with the Arp1 Minifilament Pointed End

1999 • 177 citations

Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued

1991 • 174 citations

Centractin is an actin homologue associated with the centrosome

1992 • 164 citations

Focusing on spindle poles

1998 • 143 citations

Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin

1993 • 120 citations

Apical Plasma Membrane Proteins and Endolyn-78 Travel through a Subapical Compartment in Polarized WIF-B Hepatocytes

1998 • 111 citations

The Involvement of the Intermediate Chain of Cytoplasmic Dynein in Binding the Motor Complex to Membranous Organelles ofXenopusOocytes

1997 • 107 citations

Overexpression of cytoplasmic dynein's globular head causes a collapse of the interphase microtubule network in Dictyostelium.

1996 • 95 citations

Characterization of the p22 Subunit of Dynactin Reveals the Localization of Cytoplasmic Dynein and Dynactin to the Midbody of Dividing Cells

1998 • 83 citations

[15] Purification of dynactin and dynein from brain tissue

1998 • 71 citations

Motor proteins: A dynamic duo

1996 • 69 citations

Role for microtubules in centrosome doubling in chinese hamster ovary cells

1999 • 58 citations

Structure and function of dynactin

1996 • 53 citations

Cytoplasmic dynein binds to phospholipid vesicles

1994 • 36 citations

Effect of colcemid on the centriole cycle in chinese hamster ovary cells

1982 • 34 citations

Identification and molecular characterization of the p24 dynactin light chain

1998 • 21 citations

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