Gene Expression in the Epididymis

Handbook of Physiology.

1960 • 10,428 citations

The Physiology of Reproduction

1988 • 7,765 citations

The Physiology of Reproduction

1988 • 3,218 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

WT-1 is required for early kidney development

1993 • 1,976 citations

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

1993 • 1,836 citations

The lipocalin protein family: structure and function

1996 • 1,658 citations

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

1925 • 1,630 citations

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

1994 • 1,589 citations

Marshall’s Physiology of Reproduction

1994 • 1,461 citations

HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo

1995 • 1,380 citations

Renal and neuronal abnormalities in mice lacking GDNF

1996 • 1,260 citations

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

1996 • 1,208 citations

Physiology of Reproduction

2000 • 1,184 citations

Defects in enteric innervation and kidney development in mice lacking GDNF

1996 • 1,169 citations

STEROID 5α-REDUCTASE: TWO GENES/TWO ENZYMES

1994 • 1,075 citations

Circular transcripts of the testis-determining gene Sry in adult mouse testis

1993 • 1,034 citations

Function of the retinoic acid receptors (RARs) during development: (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants

1994 • 987 citations

Tissue Distribution and Quantitative Analysis of Estrogen Receptor-α (ERα) and Estrogen Receptor-β (ERβ) Messenger Ribonucleic Acid in the Wild-Type and ERα-Knockout Mouse

1997 • 968 citations

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1984 • 906 citations

A role for oestrogens in the male reproductive system

1997 • 872 citations

Pax-2 controls multiple steps of urogenital development

1995 • 865 citations

Expression of the c-ret proto-oncogene during mouse embryogenesis

1993 • 831 citations

Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility.

1996 • 827 citations

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.

1995 • 804 citations

Cellular Biology and Biochemistry of the Retinoids

1984 • 730 citations

Tissue distribution and ontogeny of steroid 5 alpha-reductase isozyme expression.

1993 • 714 citations

Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism

1991 • 641 citations

Insights from the study of animals lacking functional estrogen receptor

1994 • 587 citations

Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system

1990 • 562 citations

The world according to bedgebog

1997 • 549 citations

High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.

1993 • 541 citations

Steroid 5α-reductase 2 deficiency

2016 • 527 citations

Sexually dimorphic sterility phenotypes in HoxalO-deficient mice

1995 • 516 citations

Retinoic Acid Receptors and Cellular Retinoid Binding Proteins: Complex Interplay in Retinoid Signaling*

1994 • 514 citations

Immunohistochemical Localization of the Androgen Receptor in Rat and Human Tissues*

1990 • 492 citations

Mechanisms of reduced fertility inHoxa-10mutant mice: uterine homeosis and loss of maternalHoxa-10expression

1996 • 480 citations

Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor.

1992 • 417 citations

Hoxa 11 structure, extensive antisense transcription, and function in male and female fertility

1995 • 390 citations

Secretory Leukocyte Protease Inhibitor: A Macrophage Product Induced by and Antagonistic to Bacterial Lipopolysaccharide

1997 • 390 citations

Tissue distribution and kinetic characteristics of rat steroid 5 alpha-reductase isozymes. Evidence for distinct physiological functions.

1992 • 375 citations

A Major Human Epididymis-Specific cDNA Encodes a Protein with Sequence Homology to Extracellular Proteinase Inhibitors1

1991 • 375 citations

Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.

1996 • 371 citations

The normal development of the blood‐testis barrier and the effects of clomiphene and estrogen treatment

1973 • 370 citations

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

1996 • 367 citations

Emx1andEmx2functions in development of dorsal telencephalon

1997 • 365 citations

Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells.

1992 • 338 citations

Biosynthesis and molecular cloning of sulfated glycoprotein 2 secreted by rat Sertoli cells

1987 • 336 citations

The CAMPATH‐1 antigen (CDw52)

1990 • 334 citations

Control of messenger RNA stability in higher eukaryotes

1996 • 315 citations

Androgen receptor expression in human tissues: an immunohistochemical study.

1991 • 310 citations

Studies on the Function of the Epididymis1

1969 • 298 citations

HOX-4 genes and the morphogenesis of mammalian genitalia.

1991 • 292 citations

Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors.

1992 • 279 citations

Estrogen receptor (alpha and beta) expression in the excurrent ducts of the adult male rat reproductive tract.

1998 • 277 citations

Primary Structure of CD52

1995 • 275 citations

Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility

1996 • 275 citations

Regulation of Epididymal Epithelial Cell Functions1

1995 • 266 citations

Immunohistochemical localization of androgen receptors with mono- and polyclonal antibodies to androgen receptor

1990 • 247 citations

Androgen Receptor Expression in Developing Male Reproductive Organs*

1991 • 244 citations

Developmental functions of mammalian Hox genes

1997 • 239 citations

The Molecules of Mammalian Fertilization

1996 • 239 citations

Epididymal epithelium: Its contribution to the formation of a luminal fluid microenvironment

1995 • 238 citations

Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis.

1996 • 237 citations

Purification and Localization of Acidic Epididymal Glycoprotein (AEG): A Sperm Coating Protein Secreted by the Rat Epididymis

1978 • 237 citations

Sperm Maturation in Rabbit Epididymis

1967 • 236 citations

ANDROGEN-CONTROLLED SPECIFIC PROTEINS IN RAT EPIDIDYMIS

1976 • 236 citations

Molecular Aspects of Mesenchymal-Epithelial Interactions

1993 • 232 citations

The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis.

1996 • 218 citations

The Human Cysteine‐Rich Secretory Protein (CRISP) Family

1996 • 218 citations

Tissue Distribution and Quantitative Analysis of Estrogen Receptor- (ER ) and Estrogen Receptor- (ER ) Messenger Ribonucleic Acid in the Wild-Type and ER -Knockout Mouse

1997 • 214 citations

Structure of the CAMPATH-1 antigen, a glycosylphosphatidylinositol-anchored glycoprotein which is an exceptionally good target for complement lysis

1993 • 208 citations

Characterization and androgen-dependence of proteins associated with luminal fluid and spermatozoa in the rat epididymis

1980 • 204 citations

Structure, Function, and Regulation of Androgen-Binding Protein/Sex Hormone-Binding Globulin

1994 • 201 citations

Estrogen Receptor Expression in Developing Epididymis, Efferent Ductules, and Other Male Reproductive Organs*

1991 • 199 citations

Development of the fertilizing ability of spermatozoa in the epididymis of the rabbit

1966 • 198 citations

PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes.

1989 • 197 citations

Reproductive aging in the male brown-Norway rat: a model for the human.

1993 • 197 citations

The epididymis and sperm maturation: a perspective

1993 • 197 citations

Potential functions of plasma steroid-binding proteins

1995 • 196 citations

Stress-induced transcription of the clusterin/apoJ gene

1997 • 196 citations

Normal and Abnormal Development of the Male Urogenital Tract

1992 • 191 citations

Estrogen Receptor (α and β) Expression in the Excurrent Ducts of the Adult Male Rat Reproductive Tract

1997 • 190 citations

Localization of Sulfated Glycoprotein-2 (Clusterin) on Spermatozoa and in the Reproductive Tract of the Male Rat1

1991 • 189 citations

On the epididymis and its role in the development of the fertile ejaculate.

1995 • 182 citations

The acid‐stable proteinase inhibitor of human mucous secretions (HUSI‐I, antileukoprotease)

1986 • 178 citations

Development of cell types and of regional differences in the postnatal rat epididymis

1979 • 176 citations

Characterization and Identification of Proteins Secreted in the Various Regions of the Adult Boar Epididymis1

1996 • 175 citations

Antileukoprotease: An Endogenous Protein in the Innate Mucosal Defense against Fungi

1997 • 173 citations

Characterization of the CAMPATH‐1 (CDw52) antigen: biochemical analysis and cDNA cloning reveal an unusually small peptide backbone

1991 • 167 citations

Molecular characterization of epididymal proteins

1998 • 167 citations

Cryptorchidism and homeotic transformations of spinal nerves and vertebrae in Hoxa-10 mutant mice.

1995 • 166 citations

Biosynthesis and molecular cloning of sulfated glycoprotein 1 secreted by rat Sertoli cells: sequence similarity with the 70-kilodalton precursor to sulfatide/GM1 activator

1988 • 166 citations

The status and the state of the human epididymis

1994 • 163 citations

Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during sperm maturation

1996 • 163 citations

Primary structure and properties of helothermine, a peptide toxin that blocks ryanodine receptors

1995 • 163 citations

Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene

1989 • 162 citations

Pax-2 is a DNA-binding protein in embryonic kidney and Wilms tumor

1992 • 162 citations

Redistribution of a rat sperm epididymal glycoprotein after in vitro and in vivo capacitation

1992 • 162 citations

Hoxb-13: a new Hox gene in a distant region of the HOXB cluster maintains colinearity

1996 • 161 citations

Mammalian sperm-egg fusion: The rat egg has complementary sites for a sperm protein that mediates gamete fusion

1992 • 154 citations

Estrogen Receptors, Estradiol, and Diethylstilbestrol in Early Development: The Mouse as a Model for the Study of Estrogen Receptors and Estrogen Sensitivity in Embryonic Development of Male and Female Reproductive Tracts*

1993 • 152 citations

Developmental roles of the retinoic acid receptors

1995 • 149 citations

Molecular cloning and characterization of HE1, a major secretory protein of the human epididymis

1996 • 149 citations

On the Epididymis and its Role in the Development of the Fertile Ejaculate

1995 • 146 citations

CARNITINE AND GLYCERYLPHOSPHORYLCHOLINE IN THE REPRODUCTIVE TRACT OF THE MALE RAT

1974 • 145 citations

MINIREVIEW: Insights into Hormonal Control of Messenger RNA Stability

1990 • 144 citations

The CRES gene: a unique testis-regulated gene related to the cystatin family is highly restricted in its expression to the proximal region of the mouse epididymis.

1992 • 144 citations

The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades.

1996 • 143 citations

Activated neu Induces Rapid Tumor Progression

1996 • 141 citations

Role of Epithelial Cells of the Male Excurrent Duct System of the Rat in the Endocytosis or Secretion of Sulfated Glycoprotein-2 (Clusterin)1

1991 • 141 citations

Molecular cloning of the cDNA for androgen‐dependent sperm‐coating glycoproteins secreted by the rat epididymis

1986 • 138 citations

Specialized Gene Expression in the Epididymis

1995 • 138 citations

Pem:A Testosterone- and LH-Regulated Homeobox Gene Expressed in Mouse Sertoli Cells and Epididymis

1996 • 137 citations

Androgen Binding Protein as a Biochemical Marker of Formation of the Blood-Testis Barrier

1975 • 135 citations

Organization of tubules in the human caput epididymidis and the ultrastructure of their epithelia

1991 • 132 citations

Reproductive parameters of older compared to younger men of infertile couples

1996 • 132 citations

Transcripts for cysteine-rich secretory protein-1 (CRISP-1; DE/AEG) and the novel related CRISP-3 are expressed under androgen control in the mouse salivary gland.

1993 • 129 citations

Expression of pro-opiomelanocortin-like gene in the testis and epididymis.

1984 • 126 citations

The extragenomic action of progesterone on human spermatozoa is influenced by redox regulated changes in tyrosine phosphorylation during capacitation

1996 • 125 citations

Pharmacology, Biology, and Clinical Applications of Androgens

1996 • 123 citations

Molecular cloning of the cDNA for two major androgen-dependent secretory proteins of 18.5 kilodaltons synthesized by the rat epididymis.

1986 • 121 citations

The epididymis as protector of maturing spermatozoa

1995 • 121 citations

Basic fibroblast growth factor (bFGF) gene expression and protein production during pubertal development of the seminiferous tubule: follicle-stimulating hormone-induced Sertoli cell bFGF expression.

1992 • 120 citations

Apolipoprotein J (clusterin) induces cholesterol export from macrophage-foam cells: a potential anti-atherogenic function?

1998 • 119 citations

Isolation, Immunolocalization, and Sperm-Association of Three Proteins of 18, 25, and 29 Kilodaltons Secreted by the Mouse Epididymis1

1992 • 115 citations

The Pem Homeobox Gene Is X-Linked and Exclusively Expressed in Extraembryonic Tissues during Early Murine Development

1994 • 115 citations

Localization of Cellular Retinol‐binding Protein and Cellular Retinoic Acid‐binding Protein in the Rat Testis and Epididymis

1985 • 113 citations

The Transfer of Retinol from Serum Retinol-binding Protein to Cellular Retinol-binding Protein Is Mediated by a Membrane Receptor

1998 • 113 citations

The glycosylphosphatidylinositol-anchored lymphocyte antigen CDw52 is associated with the epididymal maturation of human spermatozoa

1993 • 112 citations

The Homeobox Gene

1996 • 110 citations

Molecular cloning and characterization of human ERM, a new member of the Ets family closely related to mouse PEA3 and ER81 transcription factors.

1994 • 108 citations

Solution Structure of Der f 2, the Major Mite Allergen for Atopic Diseases

1998 • 107 citations

Collection of Rete Testis Fluid from Rats Without Previous Efferent Duct Ligation

1979 • 106 citations

Characterization of a Human Glycoprotein with a Potential Role in Sperm–Egg Fusion: cDNA Cloning, Immunohistochemical Localization, and Chromosomal Assignment of the Gene (AEGL1)

1996 • 106 citations

Mouse androgen‐dependent epididymal glycoprotein crisp‐1 (DE/AEG): Isolation, biochemical characterization, and expression in recombinant form

1995 • 105 citations

Purification, Radioimmunoassay, and Immunohistochemical Localization of a Glycoprotein Produced by the Rat Epididymis

1980 • 105 citations

Genetic evidence for an androgen-regulated epididymal secretory glutathione peroxidase whose transcript does not contain a selenocysteine codon

1992 • 103 citations

Transient and locally restricted expression of the ros1 protooncogene during mouse development.

1991 • 102 citations

2 The Role of the Epididymis in the Protection of Spermatozoa

1996 • 102 citations

Regulation of membrane stability and the acrosome reaction in mammalian sperm

1997 • 101 citations

Cell Type Specific Expression of Steroid 5α-Reductase 2

1994 • 101 citations

The Brown Norway Rat as a Model of Male Reproductive Aging: Evidence for Both Primary and Secondary Testicular Failure

1994 • 101 citations

Regulation of Gamma-Glutamyl Transpeptidase Catalytic Activity and Protein Level in the Initial Segment of the Rat Epididymis by Testicular Factors: Role of Basic Fibroblast Growth Factor1

1998 • 99 citations

Testicular Steroidogenesis in the Aging Brown Norway Rat

1993 • 99 citations

Morphologische Studien am Nebenhoden des Menschen

1969 • 98 citations

Analysis of growth factor and receptor mRNA levels during development of the rat seminal vesicle and prostate

1997 • 98 citations

Tissue and developmental distribution, dependence upon testicular factors and attachment to spermatozoa of GPX5, a murine epididymis-specific glutathione peroxidase

1997 • 98 citations

Developmental pattern and regulation by androgens of androgen receptor expression in the urogenital tract of the rat

1995 • 97 citations

Steroids in Fluids and Sperm Entering and Leaving the Bovine Epididymis, Epididymal Tissue, and Accessory Sex Gland Secretions¹

1976 • 96 citations

A mammalian epididymal protein with remarkable sequence similarity to snake venom haemorrhagic peptides

1992 • 96 citations

A Spermatozoa-Associated Factor Regulates Proenkephalin Gene Expression in the Rat Epididymis

1990 • 95 citations

Effects of Elevated Temperature on the Epididymis and Testis: Experimental Studies

1991 • 94 citations

Region‐specific variation of gene expression in the human epididymis as revealed by in situ hybridization with tissue‐specific cDNAs

1993 • 92 citations

A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone

1993 • 89 citations

Mouse submandibular glands express an androgen-regulated transcript encoding an acidic epididymal glycoprotein-like molecule

1992 • 89 citations

An activated allele of the c-erbB-2 oncogene impairs kidney and lung function and causes early death of transgenic mice

1993 • 89 citations

Immunolocalization of receptors for androgen and estrogen in male caprine reproductive tissues: unique distribution of estrogen receptors in efferent ductule epithelium

1997 • 87 citations

Retinoid‐binding proteins: structural determinants important for function

1995 • 86 citations

Cloning and analysis of mRNAs expressed specifically in the human epididymis

1990 • 86 citations

Isolation and characterization of a rat cDNA clone encoding a secreted superoxide dismutase reveals the epididymis to be a major site of its expression

1993 • 86 citations

Estrogen Receptor in the Ductuli Efferentes, Epididymis, and Testis of Rhesus and Cynomolgus Macaques1

1990 • 85 citations

The Effect of Aging on the Seminiferous Epithelium of the Brown Norway Rat

1993 • 85 citations

EGF-TM7: a novel subfamily of seven-transmembrane-region leukocyte cell-surface molecules

1996 • 84 citations

Equine CRISP-3: primary structure and expression in the male genital tract

1998 • 82 citations

Reproductive aging in the male brown-Norway rat: a model for the human

1993 • 82 citations

Cloning of a Human Epididymis-Specific mRNA, HE6, Encoding a Novel Member of the Seven Transmembrane-Domain Receptor Superfamily

1997 • 80 citations

Regulators of Sperm function

1996 • 80 citations

Molecular Cloning and Characterization of a Novel Human Sperm Antigen (HE2) Specifically Expressed in the Proximal Epididymis1

1994 • 79 citations

Secretory Leucocyte Protease Inhibitor in the Male Genital Tract: PSA‐Induced Proteolytic Processing in Human Semen and Tissue Localization

1995 • 79 citations

Androgen‐Regulated Epididymal Secretory Proteins Associated with Post‐testicular Sperm Developmenta

1987 • 79 citations

Molecular characterization of the ets-related human transcription factor ER81.

1995 • 77 citations

Studies on the Binding of a 32K Rat Epididymal Protein to Rat Epididymal Spermatozoa

1982 • 77 citations

Structural organization and regulation of the gene for the androgen-dependent glutathione peroxidase-like protein specific to the mouse epididymis.

1993 • 77 citations

Sulfated Glycoprotein-1 (Saposin Precursor) in the Reproductive Tract of the Male Rat1

1989 • 76 citations

Cell-type-specific expression of rat steroid 5 alpha-reductase isozymes.

1993 • 76 citations

Biology of the Scrotum. I. Temperature and Androgen as Determinants of the Sperm Storage Capacity of the Rat Cauda Epididymidis

1982 • 74 citations

Expression of multiple gamma-glutamyl transpeptidase messenger ribonucleic acid transcripts in the adult rat epididymis is differentially regulated by androgens and testicular factors in a region-specific manner.

1994 • 74 citations

The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase

1998 • 73 citations

Interaction of the human epididymal protein CD52 (HE5) with epididymal spermatozoa from men and cynomolgus monkeys

1997 • 71 citations

ADAM7, A Member of the ADAM (A Disintegrin And Metalloprotease) Gene Family Is Specifically Expressed in the Mouse Anterior Pituitary and Epididymis¹

1997 • 71 citations

SEQUENCES OF INTEREST: Molecular Cloning of Complementary Deoxyribonucleic Acid for an Androgen-Regulated Epididymal Protein: Sequence Homology with Metalloproteins

1988 • 70 citations

Identification of a functional androgen response element in the promoter of the gene for the androgen-regulated aldose reductase-like protein specific to the mouse vas deferens.

1994 • 69 citations

Diverse Secretory Patterns of Clusterin by Epididymis and Prostate/Seminal Vesicles Undergoing Cell Regression after Orchiectomy*

1990 • 67 citations

Influence of abdominal temperature on epididymal function in the rat and rabbit

1978 • 67 citations

In vitro expression of a mouse tissue specific glutathione-peroxidase-like protein lacking the selenocysteine can protect stably transfected mammalian cells against oxidative damage

1996 • 67 citations

Emx 2 developmental expression in the primordia of the reproductive and excretory systems

1997 • 67 citations

The Proenkephalin Gene Is Widely Expressed within the Male and Female Reproductive Systems of the Rat and Hamster*

1986 • 65 citations

Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2

1997 • 63 citations

The CRES gene: a unique testis-regulated gene related to the cystatin family is highly restricted in its expression to the proximal region of the mouse epididymis

1992 • 63 citations

Identification of Novel Pax-2 Binding Sites by Chromatin Precipitation

1996 • 62 citations

Structure and turnover of junctional complexes between principal cells of the rat epididymis

1995 • 62 citations

Transient appearance of CRES protein during spermatogenesis and caput epididymal sperm maturation

1995 • 61 citations

Purification and crystallization of a retinoic acid-binding protein from rat epididymis. Identity with the major androgen-dependent epididymal proteins.

1990 • 60 citations

Distribution and Tissue Expression of Semenogelin I and II in Man as Demonstrated by In Situ Hybridization and Immunocytochemistry

1996 • 60 citations

Regulation of sulfated glycoprotein-2 (clusterin) messenger ribonucleic acid in the rat epididymis.

1992 • 59 citations

Murine Pax-2 Protein Is a Sequence-SpecificTrans-Activator with Expression in the Genital System

1993 • 58 citations

Overexpression of Androgen-Binding Protein/Sex Hormone-Binding Globulin in Male Transgenic Mice: Tissue Distribution and Phenotypic Disorders1

1997 • 58 citations

Low Density Lipoprotein Receptor-Related Protein-2 Expression in Efferent Duct and Epididymal Epithelia: Evidence in Rats for its in Vivo Role in Endocytosis of Apolipoprotein J/Clusterin1

1996 • 57 citations

Cellular retinol-binding protein messenger RNA levels in normal and retinoid-deficient rats.

1990 • 57 citations

Functional Equivalence and Rescue Among Group 11HoxGene Products in Vertebral Patterning

1996 • 57 citations

An Androgen-Regulated Homeobox Gene Expressed in Rat Testis and Epididymis1

1996 • 56 citations

Expression of the proopiomelanocortin gene is developmentally regulated and affected by germ cells in the male mouse reproductive system.

1987 • 56 citations

Primary Structure of EPV20, a Secretory Glycoprotein Containing a Previously Uncharacterized Type of Domain

1997 • 56 citations

The role of EGF in testosterone-induced reproductive tract differentiation

1991 • 55 citations

Differential Regulation of Steady State 4-Ene Steroid 5α-Reductase Messenger Ribonucleic Acid Levels along the Rat Epididymis*

1991 • 55 citations

Protein Synthesis and Secretion by the Rat Caput Epididymidis in Vivo: Influence of the Luminal Microenvironment1

1995 • 54 citations

Molecular cloning and characterization of the epididymis-specific glutathione peroxidase-like protein secreted in the porcine epididymal fluid

1997 • 54 citations

Distribution and regulation of epithelial cadherin messenger ribonucleic acid and immunocytochemical localization of epithelial cadherin in the rat epididymis.

1992 • 53 citations

Structure and expression of the rat epididymal secretory protein I gene. An androgen-regulated member of the lipocalin superfamily with a rare splice donor site

1992 • 53 citations

Estrogen and progesterone receptors and estrogen receptor-related antigen (ER-D5) in human epididymis

1997 • 52 citations

Potential contraceptive use of epididymal proteins: evidence for the participation of specific antibodies against rat epididymal protein DE in male and female fertility inhibition

1995 • 52 citations

The effect of androgens and antiandrogens on the immunohistochemical localization of the androgen receptor in accessory reproductive organs of male rats

1994 • 51 citations

Receptor tyrosine kinase c-ros knockout mice as a model for the study of epididymal regulation of sperm function.

1998 • 51 citations

Structural organization and regulation of the gene for the androgen- dependent glutathione peroxidase-like protein specific to the mouse epididymis

1993 • 50 citations

Transcripts for cysteine-rich secretory protein-1 (CRISP-1; DE/AEG) and the novel related CRISP-3 are expressed under androgen control in the mouse salivary gland

1993 • 49 citations

Membrane Glycoproteins from Spermatozoa: Partial Characterization of an Integral Mr = ∿24,000 Molecule from Rat Spermatozoa that is Glycosylated during Epididymal Maturation1

1986 • 48 citations

Characterization of a cell surface glycoprotein associated with maturation of rat spermatozoa

1994 • 48 citations

Characterization of an acidic glycoprotein secreted by principal cells of the rat epididymis

1981 • 48 citations

Endogenous Retinoids in Rat Epididymal Tissue and Rat and Human Spermatozoa1

1993 • 47 citations

Androgen Receptor and 5α-Reductase Activity in the Ductuli Efferentes and Epididymis of Adult Rhesus Macaques1

1991 • 47 citations

In situ histochemical analysis of region‐specific gene expression in the adult rat epididymis

1991 • 47 citations

Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene

1997 • 46 citations

Identification, Expression, and Regulation of the Transcriptional Factor Polyomavirus Enhancer Activator 3, and its Putative Role in Regulating the Expression of Gamma-Glutamyl Transpeptidase mRNA-IV in the Rat Epididymis1

1997 • 45 citations

Region-specific expression of the androgen receptor in the human epididymis

1997 • 45 citations

Characterization of an androgen response element within the promoter of the epididymis-specific murine glutathione peroxidase 5 gene

1997 • 44 citations

Ubiquitous expression of the androgen receptor and testis-specific expression of the FSH receptor in the cynomolgus monkey (Macaca fascicularis) revealed by a ribonuclease protection assay

1995 • 44 citations

Characterization of a maturation-associated glycoprotein on the plasma membrane of rat caudal epididymal sperm.

1984 • 44 citations

Regulation of the epididymal glutathione peroxidase-like protein in the mouse: Dependence upon androgens and testicular factors

1992 • 43 citations

The PEA3 protein of theEts oncogene family is a putative transcriptional modulator of the mouse epididymis-specific glutathione peroxidase genegpx5

1998 • 43 citations

In vivo secretion and association of clusterin (SGP‐2) in luminal fluid with spermatozoa in the rat testis and epididymis

1991 • 43 citations

Male Infertility Caused by Epididymal Dysfunction in Transgenic Mice Expressing a Dominant Negative Mutation of Retinoic Acid Receptor α1

1997 • 43 citations

Regulation of mouse epididymal epithelium in vitro by androgens, temperature and fibroblasts

1997 • 42 citations

Body temperature (37 C) specifically down-regulates the messenger ribonucleic acid for the major sperm surface antigen CD52 in epididymal cell culture.

1996 • 42 citations

Specific Distribution of Messenger Ribonucleic Acids for 24-Kilodalton Proteins in the Mouse Epididymis as Revealed by in Situ Hybridization: Developmental Expression and Regulation in the Adult1

1991 • 42 citations

Region-Specific Localization of Retinoic Acid Receptor-α Expression in the Rat Epididymis

1996 • 42 citations

Homeobox genes and male reproductive development

1996 • 42 citations

Fine structure of the Wolffian duct and cytodifferentiation of the epididymis in fetal rats

1969 • 42 citations

Rat epididymis‐specific sperm maturation antigens. I. Evidence that the 26 kD 4E9 antigen found on rat caudal epididymal sperm tail is derived from a protein secreted by the epididymis

1994 • 41 citations

Gene expression in the dog epididymis: a model for human epididymal function

1994 • 41 citations

Sequence homology of androgen-regulated epididymal proteins with glutathione peroxidase in mice

1991 • 41 citations

The segment-specific pattern of A-raf expression in the mouse epididymis is regulated by testicular factors.

1995 • 39 citations

Developmental Expression of an Androgen-Regulated Epididymal Protein*

1989 • 39 citations

Molecular cloning and sequence analysis of the cDNA encoding the human acrosin‐trypsin inhibitor (HUSI‐II)

1991 • 39 citations

Sertoli cells in testes containing or lacking germ cells: A comparative study of paracrine effects using the W (c‐kit) gene mutant mouse model

1994 • 39 citations

Molecular cloning and characterization of EPI-1, the major protein in chimpanzee (Pan troglodytes) cauda epididymal fluid

1996 • 39 citations

Androgen-regulated proliferation and gene transcription in a prostate smooth muscle cell line (PS-1).

1996 • 39 citations

Epidermal growth factor binding and receptor distribution in the mouse reproductive tract during development

1990 • 38 citations

The major maturation glycoprotein found on rat cauda epididymal sperm surface is linked to the membrane via phosphatidylinositol

1989 • 37 citations

A Major Messenger Ribonucleic Acid of the Rodent Epididymis Encodes a Small Glycosylphosphatidylinositol-Anchored Lymphocyte Surface Antigen1

1994 • 37 citations

Investigations on the Relationship between Sperm Fertilizing Ability and Androgen-Binding Protein in the Restricted Rat^*

1984 • 37 citations

Multiple Forms of Gamma-Glutamyl Transpeptidase Messenger Ribonucleic Acid are Expressed in the Adult Rat Testis and Epididymis1

1994 • 37 citations

Early step in mammalian sex determination

1996 • 36 citations

Differential Patterns of Regulated Gene Expression in the Adult Rat Epididymis^a

1991 • 36 citations

Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis

1998 • 36 citations

Gene Expression in the Aging Brown Norway Rat Epididymis

1995 • 35 citations

Mapping of Human γ-Glutamyl Transpeptidase Genes on Chromosome 22 and Other Human Autosomes

1993 • 35 citations

The role of epidermal growth factor receptor (EGFR) in male reproductive tract differentiation: stimulation of EGFR expression and inhibition of Wolffian duct differentiation with anti-EGFR antibody.

1996 • 35 citations

The influence of body temperature and castration on the protein composition of fluid in the rat cauda epididymidis

1986 • 35 citations

The monkey ESP14.6 mRNA, a novel transcript expressed at high levels in the epididymis

1995 • 34 citations

Evidence for an Organ- and Sex-Specific Role of Basic Fibroblast Growth Factor in the Development of the Fetal Mammalian Reproductive Tract*

1991 • 34 citations

Epididymal storage at abdominal temperature reduces the time required for capacitation of hamster spermatozoa

1991 • 34 citations

Basic fibroblast growth factor (bFGF) gene expression and protein production during pubertal development of the seminiferous tubule: follicle-stimulating hormone-induced Sertoli cell bFGF expression

1992 • 34 citations

Analysis of transcripts encoding novel members of the mammalian metalloprotease-like, disintegrin-like, cysteine-rich (MDC) protein family and their expression in reproductive and non-reproductive monkey tissues

1995 • 34 citations

The major androgen-regulated secretory proteins of the rat epididymis bear sequence homology with members of the alpha 2u-globulin superfamily.

1987 • 34 citations

In Vitro Androgen-Induced Growth and Morphogenesis of the Wolffian Duct within Urogenital Ridge*

1991 • 34 citations

Morphological Basis of Human Reproductive Function

1987 • 33 citations

Cloning of the mouse gene encoding plasma glutathione peroxidase: organization, sequence and chromosomal localization

1995 • 33 citations

Identification and gene cloning of a new phosphatidylinositol-linked antigen expressed on mature lymphocytes. Down-regulation by lymphocyte activation.

1990 • 33 citations

LESP, an androgen-regulated lizard epididymal secretory protein family identified as a new member of the lipocalin superfamily

1993 • 33 citations

The 18-kDa Mouse Epididymal Protein (MEP 10) Binds Retinoic Acid1

1992 • 32 citations

Investigations on the Relationship between Sperm Fertilizing Ability and Androgen-Binding Protein in the Hypophysectomized, pregnenoloneenolone-Injected Rat^*

1984 • 31 citations

Regulation of sulfated glycoprotein-2 (clusterin) messenger ribonucleic acid in the rat epididymis

1992 • 31 citations

Regional variation of specific gene expression in the dog epididymis as revealed by in‐situ transcript hybridization

1994 • 31 citations

Activation of androgen receptor in epidermal growth factor modulation of fetal mouse sexual differentiation

1996 • 30 citations

Localization of Cellular Retinol-Binding Protein mRNA in Rat Testis and Epididymis and its Stage-Dependent Expression during the Cycle of the Seminiferous Epithelium1

1990 • 30 citations

Expression and tissue distribution of rat sulfated glycoprotein-1 (prosaposin).

1996 • 30 citations

Identification of an abundant monkey epididymal transcript encoding a homologue of human CAMPATH-1 antigen precursor

1992 • 30 citations

ADAM7, A Member of the ADAM (A Disintegrin And Metalloprotease) Gene Family Is Specifically Expressed in the Mouse Anterior Pituitary and Epididymis

1997 • 29 citations

Differential methylation in steroid 5 alpha-reductase isozyme genes in epididymis, testis, and liver of the adult rat.

1997 • 29 citations

Tissue‐specific gene expression as an indicator of epididymis‐specific functional status in the boar, bull and stallion

1993 • 29 citations

In vitro androgenic induction of a major protein in epithelial cell subcultures from mouse vas deferens.

1992 • 29 citations

Identification of a second promoter which drives the expression of .gamma.-glutamyl transpeptidase in rat kidney and epididymis

1992 • 28 citations

Expression of the Rat .gamma.-Glutamyl Transpeptidase Gene from a Specific Promoter in the Small Intestine and in Hepatoma Cells

1994 • 27 citations

Identification of the rat epididymis-secreted 4E9 antigen as protein E: Further biochemical characterization of the highly homologous epididymal secretory proteins D and E

1996 • 27 citations

Members of the rafgene family exhibit segment‐specific patterns of expression in mouse epididymis

1993 • 27 citations

Expression of multiple gamma-glutamyl transpeptidase messenger ribonucleic acid transcripts in the adult rat epididymis is differentially regulated by androgens and testicular factors in a region-specific manner

1994 • 27 citations

The 26 kD protein recognized on rat cauda epididymal sperm by monoclonal antibody 4E9 has internal peptide sequence that is identical to the secreted form of epididymal protein E1

1997 • 26 citations

Temperature and androgens regulate the biosynthesis of secretory proteins from rabbit cauda epididymidis

1993 • 26 citations

Major human epididymis‐specific gene product, HE3, is the first representative of a novel gene family

1994 • 26 citations

Biology of the Scrotum. II. Suppression by Abdominal Temperature of Transepithelial Ion and Water Transport in the Cauda Epididymidis

1982 • 25 citations

Assessment of protein synthesis and secretion by rat seminiferous and epididymal tubules in vivo

1994 • 25 citations

Expression of 4-ene steroid 5 alpha-reductase messenger ribonucleic acid in the rat epididymis during postnatal development.

1992 • 25 citations

Stimulation of epidermal growth factor gene expression during the fetal mouse reproductive tract differentiation: role of androgen and its receptor.

1996 • 25 citations

Body temperature (37 C) specifically down-regulates the messenger ribonucleic acid for the major sperm surface antigen CD52 in epididymal cell culture

1996 • 25 citations

Developmental expression of sulfated glycoprotein‐2 in the epididymis of the rat

1994 • 24 citations

PAX-2: A Developmental Gene Constitutively Expressed in the Mouse Epididymis and Ductus Deferens

1996 • 24 citations

Aging male reproductive system: Changes in the epididymis

1980 • 23 citations

Development of Male Urogenital Epithelia Elicited by Soluble Mesenchymal Factors

1995 • 23 citations

Differential Methylation in Steroid 5α‐Reductase Isozyme Genes in Epidydimis, Testis, and Liver of the Adult Rat

1997 • 22 citations

Post-testicular development of mammalian spermatozoa

1987 • 22 citations

Movements of the luminal contents in two different regions of the caput epididymidis of the rat in vitro.

1983 • 21 citations

Regionalized expression of CD52 in rat epididymis is related to mRNA poly(A) tail length

1997 • 20 citations

5 alpha-reductase activity in developing urogenital tracts of fetal and neonatal male mice.

1994 • 20 citations

Distribution and regulation of epithelial cadherin messenger ribonucleic acid and immunocytochemical localization of epithelial cadherin in the rat epididymis

1992 • 19 citations

Dog epididymis-specific mRNA encoding secretory glutathione peroxidase-like protein

1998 • 19 citations

In vitro androgenic induction of a major protein in epithelial cell subcultures from mouse vas deferens

1992 • 19 citations

Sequence analysis of monkey acrosin-trypsin inhibitor transcripts and their abundant expression in the epididymis

1993 • 18 citations

An 18-kDa Androgen-regulated Protein that Modifies Galactosyltransferase Activity is Synthesized by the Rat Caput Epididymidis, but has no Structural Similarity to Rat Milk Alphalactalbumin1

1990 • 18 citations

Intraluminal Androgen Binding Protein Alters 3H-Androgen Uptake by Rat Epididymal Tubules in Vitro1

1990 • 16 citations

Biology of the Scrotum. III. Effects of Abdominal Temperature upon the Epithelial Cells of the Rat Cauda Epididymidis

1982 • 14 citations

Expression of 4-ene steroid 5 alpha-reductase messenger ribonucleic acid in the rat epididymis during postnatal development

1992 • 14 citations

Identification of a Rabbit Epididymal Protein Gene

1996 • 14 citations

The role of epidermal growth factor receptor (EGFR) in male reproductive tract differentiation: stimulation of EGFR expression and inhibition of Wolffian duct differentiation with anti-EGFR antibody

1996 • 13 citations

Stimulation of epidermal growth factor gene expression during the fetal mouse reproductive tract differentiation: role of androgen and its receptor

1996 • 13 citations

The segment-specific pattern of A-raf expression in the mouse epididymis is regulated by testicular factors

1995 • 13 citations

Developmental Regulation of Expression of Multiple γ-Glutamyl-Transpeptidase mRNAs in the Postnatal Rat Epididymis

1994 • 12 citations

Marshall's Physiology of Reproduction, vol.2. Reproduction in Male.

1991 • 12 citations

5 alpha-reductase activity in developing urogenital tracts of fetal and neonatal male mice

1994 • 11 citations

Regional distribution of 5alpha-reductase type 1 and type 2 mRNA along the nonhuman primate (Macaca fascicularis) epididymis.

1998 • 10 citations

A processed homeobox gene expressed in a stage-, tissue- and region-specific manner in epididymis

1997 • 10 citations

Epididymis: Role and importance in male infertility treatment

1996 • 10 citations

Regional Distribution of 5α‐Reductase Type 1 and Type 2 mRNA Along the Nonhuman Primate (Macaca fascicularis) Epididymis

1997 • 8 citations

Androgen-regulated proliferation and gene transcription in a prostate smooth muscle cell line (PS-1)

1996 • 6 citations

The Secretory Activity of the Maturing Epididymis Compared with Maturational Changes in Other Reproductive Organs of the Foetus, Infant and Child

1965 • 5 citations

SYNTHESIS and REGULATION OF PORCINE EPIDIDYMAL SECRETORY PROTEINS

1995 • 2 citations