Structure, Function, and Regulation of Androgen-Binding Protein/Sex Hormone-Binding Globulin

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

The Physiology of Reproduction

1988 • 3,218 citations

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

1991 • 2,763 citations

Progressive sequence alignment as a prerequisitetto correct phylogenetic trees

1987 • 1,899 citations

[47] Establishing homologies in protein sequences

1983 • 1,187 citations

SEX‐HORMONE‐BINDING GLOBULIN

1974 • 1,119 citations

3 The sertoli cell

1992 • 938 citations

The Free Hormone Hypothesis: A Physiologically Based Mathematical Model*

1989 • 925 citations

An Animal Model for Cystic Fibrosis Made by Gene Targeting

1992 • 921 citations

Structure and function of laminin: anatomy of a multidomain glycoprotein

1990 • 812 citations

The Serum Transport of Steroid Hormones

1982 • 777 citations

Inhibition of Sex Hormone-Binding Globulin Production in the Human Hepatoma (Hep G2) Cell Line by Insulin and Prolactin*

1988 • 682 citations

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia

1990 • 669 citations

The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade.

1993 • 589 citations

The Functions of Corticosteroid-Binding Globulin and Sex Hormone-Binding Globulin: Recent Advances*

1990 • 559 citations

slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.

1990 • 499 citations

Testicular Development, Structure, and Function.

1980 • 489 citations

Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.

1988 • 486 citations

The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily

1991 • 455 citations

Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing

1989 • 437 citations

Merosin, a tissue-specific basement membrane protein, is a laminin-like protein.

1990 • 398 citations

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

1989 • 348 citations

Effects of follicle-stimulating hormone on cultures of sertoli cell preparations

1975 • 345 citations

Fluctuations in Plasma Testosterone Levels in Adult Male Rats and Mice

1973 • 342 citations

Steroid-Protein Interaction with Particular Reference to Testosterone Binding by Human Serum

1967 • 326 citations

On the Androgen Microenvironment of Maturing Spermatozoa^*

1984 • 326 citations

Molecular Properties of Corticosteroid Binding Globulin and the Sex-Steroid Binding Proteins*

1990 • 312 citations

Measurement of Free Hormones in Blood

1990 • 312 citations

Structure and expression of a rat agrin

1991 • 310 citations

EGF‐like domains in extracellular matrix proteins: Localized signals for growth and differentiation?

1989 • 304 citations

Reduced Clearance Rate of Thyroxine-Binding Globulin (TBG) with Increased Sialylation: A Mechanism for Estrogen-Induced Elevation of Serum TBG Concentration*

1987 • 301 citations

Testicular peritubular cells secrete a protein under androgen control that modulates Sertoli cell functions.

1985 • 271 citations

Sex Hormone Binding Globulin: Origin, Function and Clinical Significance

1990 • 267 citations

Studies on the binding of testosterone to human plasma

1968 • 252 citations

Human basement membrane heparan sulfate proteoglycan core protein: a 467-kD protein containing multiple domains resembling elements of the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor.

1992 • 241 citations

REGULATION OF THE TESTIS SERTOLI CELL BY FOLLICLE STIMULATING HORMONE

1980 • 236 citations

Follicle-Stimulating Hormone, the Sertoli Cell, and Spermatogenesis

1976 • 235 citations

A High-Affinity Androgen-Binding Protein (ABP) in Rat Testis: Evidence for Secretion into Efferent Duct Fluid and Absorption by Epididymis1

1973 • 212 citations

Laminins and other strange proteins

1992 • 209 citations

Isolation and Culture of FSH Responsive Sertoli Cells

1975 • 208 citations

Sexual differentiation: Basic and clinical aspects

1984 • 194 citations

Biochemical Actions of Hormones

1980 • 191 citations

Species Distribution of Testosterone-Binding Globulin1

1973 • 188 citations

Coagulation factors X, Xa, and protein S as potent mitogens of cultured aortic smooth muscle cells.

1992 • 184 citations

Hormone Binding and Target Cell Activation in the Testis

1974 • 183 citations

The control of the interaction of sex hormone-binding globulin with its receptor by steroid hormones.

1990 • 176 citations

Testosterone-Binding Levels in the Serum of Women During the Normal Menstrual Cycle, Pregnancy, and the Post-partum Period

1967 • 175 citations

Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.

1990 • 173 citations

On the regulation of sex-hormone-binding globulin—A challenge of an old dogma and outlines of an alternative mechanism

1989 • 167 citations

Sites of Action of Androgens and Follicle Stimulating Hormone on Cells of the Seminiferous Tubule

1978 • 158 citations

FSH Stimulation of Testicular Androgen Binding Protein

1973 • 155 citations

Isolation and characterization of the testosterone-estradiol-binding globulin from human plasma. Use of a novel affinity column

1975 • 153 citations

An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins.

1991 • 150 citations

The plasma sex steroid binding protein (SBP or SHBG). A critical review of recent developments on the structure, molecular biology and function

1991 • 148 citations

Functional binding of the "TATA" box binding component of transcription factor TFIID to the -30 region of TATA-less promoters.

1992 • 147 citations

Testosterone-estradiol-binding globulin binds to human prostatic cell membranes

1985 • 146 citations

A recognition system for sex-hormone-binding protein-estradiol complex in human decidual endometrium plasma membranes

1984 • 143 citations

Studies of Testosterone Binding Globulin¹

1968 • 141 citations

Immunoassay of Androgen Binding Protein in Blood: A New Approach for Study of the Seminiferous Tubule

1978 • 140 citations

Demonstration of Androgen-Binding Components in Rat Epididymis Cytosol and Comparison with Binding Components in Prostate and Other Tissues1

1971 • 140 citations

Regulation by FSH and dibutyryl cyclic AMP of the formation of androgen-binding protein in Sertoli cell-enriched cultures

1976 • 138 citations

Analysis of Sertoli Cell-Secreted Proteins by Two-Dimensional Gel Electrophoresis

1982 • 136 citations

Estradiol causes the rapid accumulation of cAMP in human prostate.

1994 • 136 citations

Androgen Binding Protein as a Biochemical Marker of Formation of the Blood-Testis Barrier

1975 • 135 citations

The cDNA‐deduced primary structure of human sex hormone‐binding globulin and location of its steroid‐binding domain

1987 • 134 citations

The Human Sex Hormone-Binding Globulin Gene Contains Exons for Androgen-Binding Protein and Two Other Testicular Messenger RNAs

1989 • 134 citations

Hormonal Regulation of Spermatogenesis

1976 • 133 citations

Protein-S, a vitamin K-dependent protein, is a bone matrix component synthesized and secreted by osteoblasts.

1992 • 130 citations

Sertoli cell origin of testicular androgen-binding protein (ABP)

1975 • 129 citations

Biologically Active Steroids Activate Receptor-Bound Human Sex Hormone-Binding Globulin to Cause LNCaP Cells to Accumulate Adenosine 3′,5′-Monophosphate*

1990 • 129 citations

The hormonal and cellular control of Sertoli cell secretion.

1983 • 128 citations

Primary structure of bovine vitamin K-dependent protein S.

1986 • 126 citations

The Free Hormone Hypothesis Distinction from the Free Hormone Transport Hypothesis

1992 • 124 citations

Stage-dependent secretion of ABP by rat seminiferous tubules

1982 • 123 citations

Immunocytochemical localization of the sex steroid-binding protein of plasma in tissues of the adult monkey Macaca nemestrina.

1980 • 120 citations

Binding of testosterone and estradiol in plasma

1968 • 119 citations

Solubilization and Partial Characterization of the Sex Hormone-binding Globulin Receptor from Human Prostate

1989 • 118 citations

HORMONAL INFLUENCES ON THE SECRETION OF STEROID-BINDING PROTEINS BY A HUMAN HEPATOMA-DERIVED CELL LINE

1984 • 117 citations

Extracellular Androgen Binding Proteins

1981 • 116 citations

SECRETION OF TESTOSTERONE-ESTRADIOL-BINDING GLOBULIN BY A HUMAN HEPATOMA-DERIVED CELL LINE

1981 • 115 citations

Immunocytochemical Localization of Androgen-Binding Protein in the Male Rat Reproductive Tract*

1981 • 114 citations

Amino acid sequence of the sex steroid binding protein of human blood plasma

1986 • 112 citations

Characterization of functionally important domains in human vitamin K-dependent protein S using monoclonal antibodies.

1990 • 112 citations

Site-specific base substitution and deletion mutations that enhance or suppress transcription of the SV40 major late RNA

1982 • 107 citations

The Laminins: A Family of Basement Membrane Glycoproteins Important in Cell Differentiation and Tumor Metastases

1993 • 105 citations

A liquid-phase immunoradiometric assay (IRMA) for human sex hormone binding globulin (SHBG)

1985 • 103 citations

Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing.

1991 • 101 citations

Laminin promotes formation of cord-like structures by sertoli cells in vitro

1990 • 101 citations

Direct measurement of androgen receptors in cultured sertoli cells

1977 • 99 citations

Electrophoretic Evidence for the Presence of an Estrogen-Binding β-Globulin in Human Plasma

1966 • 97 citations

Cloning and characterization of human liver cDNA encoding a protein S precursor.

1987 • 97 citations

Sex hormone‐binding globulin, androgen‐binding protein, and vitamin K‐dependent protein S are homologous to laminin A, merosin, and Drosophila crumbs protein

1992 • 97 citations

Characterization of the human sex hormone binding globulin (SHBG) gene and demonstration of two transcripts in both liver and testis

1989 • 96 citations

Observations on the binding of androgens by rat testis seminiferous tubules and testis extracts

1974 • 96 citations

Follicle-Stimulating Hormone and Testosterone Independently Increase the Production of Androgen- Binding Protein by Sertoli Cells in Culture*

1979 • 95 citations

Sertoli cells secrete both testis-specific and serum proteins.

1981 • 93 citations

Molecular biology of the Sertoli cell.

1988 • 92 citations

Synthetic peptides from the carboxy-terminal globular domain of the A chain of laminin: their ability to promote cell adhesion and neurite outgrowth, and interact with heparin and the beta 1 integrin subunit.

1991 • 91 citations

SEQUENCES OF INTEREST: Homologous Sequences in Steroidogenic Enzymes, Steroid Receptors and a Steroid Binding Protein Suggest a Consensus Steroid-Binding Sequence

1988 • 90 citations

Localization of the human sex hormone-binding globulin gene (SHBG) to the short arm of chromosome 17 (17p12→p13)

1990 • 89 citations

A cDNA coding for human sex hormone binding globulin Homology to vitamin K‐dependent protein S

1987 • 89 citations

Regulation of Sex Hormone Binding Globulin (SHBG) production in hep G2 cells by insulin

1988 • 88 citations

The hormonal and cellular conrol of Sertoli cell secretion

1983 • 88 citations

Rat androgen-binding protein: evidence for identical subunits and amino acid sequence homology with human sex hormone-binding globulin.

1987 • 85 citations

The molecular and cellular endocrinology of the testis

1990 • 85 citations

An Androgen Binding Protein in the Testicular Cytosol of Human Testis

1978 • 83 citations

Follicle-Stimulating Hormone Induces Transient Expression of the Protooncogene c-fos in Primary Sertoli Cell Cultures

1988 • 80 citations

Selective uptake and metabolism of androgens by rat epididymis. The presence of a cytoplasmic receptor

1971 • 78 citations

Androgen-binding protein. Purification from rat epididymis, characterization, and immunocytochemical localization.

1981 • 77 citations

Characterization of a Cytoplasmic Receptor for 5±–Dihydrotestosterone in the Caput Epididymidis of Intact Rabbits1

1973 • 77 citations

Specific steroid-binding glycoproteins of human blood plasma: Novel data on their structure and function

1990 • 77 citations

The Gene Structure of Rat Androgen-Binding Protein: Identification of Potential Regulatory Deoxyribonucleic Acid Elements of a Follicle-Stimulating Hormone-Regulated Protein

1988 • 75 citations

Sex Hormone-Binding Globulin Secretion by Human Hepatocarcinoma Cells Is Increased by Both Estrogens and Androgens*

1987 • 75 citations

Androgen binding protein as a marker for sertoli cell function

1981 • 75 citations

Purification and characterization of the sex steroid-binding protein of rabbit serum. Comparison with the human protein

1978 • 73 citations

Androgen Binding Protein (ABP) in Fluids Collected from the Rete Testis and Cauda Epididymidis of Sexually Mature and Immature Rabbits and Observations on Morphological Changes in the Epididymis Following Ligation of the Ductuli Efferentes1

1977 • 72 citations

Purification and characterization of androgen binding protein from the rabbit epididymis

1982 • 72 citations

Direct effect of sex steroid-binding protein (SBP) of plasma on the metabolic clearance rate of testosterone in the rhesus macaque

1985 • 71 citations

Radioimmunoassay for Human Testosterone-Estradiol Binding Globulin*

1982 • 68 citations

A Novel Affinity Column for Isolation of Androgen Binding Protein from Rat Epididymis

1977 • 66 citations

Characterization of an androgen binding protein (ABP) in rat testis and epididymis

1973 • 66 citations

Purification of the sex steroid binding protein from human serum

1975 • 66 citations

The Androgen-Binding Protein Gene Is Expressed in Male and Female Rat Brain*

1990 • 65 citations

Vitamin K-dependent protein S is similar to rat androgen-binding protein

1987 • 65 citations

Hormonal and immunological aspects of the phylogeny of sex steroid binding plasma protein.

1980 • 65 citations

Electron Microscope Radioautographic Evidence ofin VivoAndrogen-Binding Protein Internalization in the Rat Epididymis Principal Cells*

1988 • 65 citations

Tissue-specific expression of the rat androgen-binding protein/sex hormone-binding globulin gene in transgenic mice

1993 • 64 citations

Physicochemical characteristics of human sex hormone binding globulin: Evidence for two identical subunits

1986 • 63 citations

There are two forms of androgen binding protein in human testes. Comparison of their protomeric variants with serum testosterone-estradiol binding globulin.

1985 • 62 citations

Photoaffinity labeling of rat androgen binding protein.

1980 • 62 citations

Biological Effects of Sex Hormone-Binding Globulin on Androgen-Induced Proliferation and Androgen Metabolism in LNCaP Prostate Cells*

1991 • 62 citations

Interaction of sex hormone-binding globulin with plasma membranes from the rat epididymis and other tissues

1994 • 62 citations

Steroidal and non-steroidal factors in plasma sex hormone binding globulin regulation

1992 • 61 citations

Estrogen and androgen regulation of sex hormone binding globulin secretion by a human liver cell line

1990 • 61 citations

THE INFLUENCE OF SERUM ON UPTAKE, CONVERSION AND ACTION OF TESTOSTERONE IN RAT PROSTATE GLANDS IN ORGAN CULTURE

1972 • 61 citations

Synergistic Effects of Follicle-Stimulating Hormone and Testosterone on the Maintenance of Spermiogenesis in Hypophysectomized Rats: Relationship with the Androgen-Binding Protein Status*

1991 • 61 citations

Steroid-binding proteins in rabbit plasma: Separation of testosterone-binding globulin (TeBG) from corticosteroid-binding globulin (CBG), preliminary characterization of TeBG, and changes in TeBG concentration during sexual maturation

1975 • 60 citations

Current status of the molecular structure and function of the plasma sex steroid-binding protein (SBP)

1983 • 60 citations

REGULATION OF SEMINIFEROUS TUBULAR FUNCTION BY FSH AND ANDROGEN

1975 • 60 citations

Further characterization and immunological studies of human sex steroid binding plasma protein

1979 • 59 citations

Testosterone-binding globulins in human plasma: studies on sex distribution and specificity

1968 • 59 citations

Steroid-protein interactions. Human corticosteroid-binding globulin: characterization of dimer and electrophoretic variants

1982 • 58 citations

Steroid-Protein Interactions II

1986 • 57 citations

Delineation and synthesis of the membrane receptor-binding domain of sex hormone-binding globulin.

1990 • 57 citations

Hormonal Influences on the Level of Testicular Androgen Binding Activity: Effect of FSH Following Hypophysectomy

1975 • 57 citations

Molecular analyses of a human sex hormone-binding globulin variant: evidence for an additional carbohydrate chain.

1992 • 56 citations

Studies on the site of origin of the androgen binding protein present in epididymal cytosol from mature intact rabbits☆

1974 • 56 citations

Stimulation by androgens of the production of androgen binding protein by cultured sertoli cells

1977 • 54 citations

Spermatogenic cells do internalize Sertoli androgen-binding protein: a transmission electron microscopy autoradiographic study in the rat.

1994 • 54 citations

Evidence that human placenta is a site of sex hormone-binding globulin gene expression

1993 • 54 citations

Further characterization of the 5α-dihydrotestosterone binding protein in the epididymal cytosol fraction. In vitro studies

1972 • 54 citations

Molecular characterization of the sex steroid binding protein (SBP) of plasma. Re-examination of rabbit SBP and comparison with the human, macaque and baboon proteins

1986 • 53 citations

Secretion and role of androgen-binding proteins in the testis and epididymis.

1976 • 53 citations

Hormonal Regulation of Androgen-Binding Protein in the Rat*

1990 • 51 citations

Biological relevance of the interaction between sex steroid binding protein and its specific receptor of MCF-7 cells: Effect on the estradiol-induced cell proliferation

1993 • 50 citations

A simple two-step procedure for the simultaneous isolation of corticosteroid binding globulin and sex hormone binding globulin from human serum by chromatography on cortisol-sepharose and phenyl-sepharose

1981 • 50 citations

The amino acid sequence of the sex steroid-binding protein of rabbit serum

1989 • 50 citations

Study of the carbohydrate moiety of human serum sex hormone-binding globulin

1983 • 50 citations

Modifications of the properties of human sex steroid-binding protein by nonesterified fatty acids.

1986 • 49 citations

Protein-S, a vitamin K-dependent protein, is a bone matrix component synthesized and secreted by osteoblasts

1992 • 49 citations

Binding of an extracellular steroid-binding globulin to membranes and soluble receptors from human breast cancer cells (MCF-7 cells).

1992 • 49 citations

Subcellular distribution and selectivity of the protein-binding component of the recognition system for sex-hormone-binding protein-estradiol complex in human decidual endometrium

1986 • 48 citations

Receptor-Mediated Endocytosis of an Extracellular Steroid-Binding Protein (TeBG) in MCF-7 Human Breast Cancer Cells*

1991 • 48 citations

Selective removal of glycosylation sites from sex hormone-binding globulin by site-directed mutagenesis.

1992 • 47 citations

Identification of Complementary DNA Clones That Encode Rat Androgen Binding Protein

1985 • 47 citations

Endocytosis of androgen-binding protein, clusterin, and transferrin in the efferent ducts and epididymis of the ram.

1991 • 46 citations

Hormonal Regulation of Rat Androgen-Binding Protein (ABP) Messenger Ribonucleic Acid and Homology of Human Testosterone-Estradiol-Binding Globulin and ABP Complementary Deoxyribonucleic Acids

1988 • 46 citations

Testicular Androgen Binding Protein (ABP) — A Parameter of Sertoli Cell Secretory Function

1975 • 46 citations

Modification in the purification of the sex steroid-binding protein of human serum by affinity chromatography

1980 • 45 citations

Immunohistochemical Localization of Sex Hormone-Binding Globulin in Normal and Neoplastic Breast Tissue

1990 • 45 citations

The Use of a Photoaffinity Ligand to Compare Androgen-Binding Protein (ABP) Present in Rat Sertoli Cell Culture Media with ABP Present in Epididymal Cytosol*

1981 • 45 citations

Selective Delivery of Sex Steroid Hormones to Tissues In Vivo by Albumin and by Sex Hormone‐Binding Globulina

1988 • 45 citations

Caractérisation et propriétés physico-chimiques de la transcortine humaine

1975 • 44 citations

Purification and characterization of androgen binding protein from the rat epididymis

1980 • 44 citations

The androgen-binding protein gene is expressed in CD1 mouse testis

1989 • 44 citations

The interaction between complement component C4b-binding protein and the vitamin K-dependent protein S forms a link between blood coagulation and the complement system

1991 • 42 citations

The plasma membrane of epididymal epithelial cells has a specific receptor which binds to androgen-binding protein and sex steroid-binding protein

1992 • 42 citations

Further Studies on the Accumulation and Binding of Androgen in Rat Epididymis

1974 • 41 citations

Effects of FSH on Levels of Androgen Binding Protein in the Testis

1974 • 41 citations

Characterization of a cDNA coding for sex steroid‐binding protein of human plasma

1987 • 41 citations

Identification of an alternate promoter in the rat androgen-binding protein/sex hormone-binding globulin gene that regulates synthesis of a messenger RNA encoding a protein with altered function.

1993 • 40 citations

Tissue Uptake of Human Sex Hormone-Binding Globulin and its Influence on Ligand Kinetics in the Adult Female Rat1

1992 • 39 citations

Cellular distribution and hormonal regulation of h-SBP in human hepatoma cells

1987 • 39 citations

Characterization of Met-139 as the photolabeled amino acid residue in the steroid binding site of sex hormone binding globulin using .DELTA.6 derivatives of either testosterone or estradiol as unsubstituted photoaffinity labeling reagents

1992 • 39 citations

The Ontogeny of Biologically Active Androgen-Binding Protein in Rat Plasma, Testis, and Epididymis*

1985 • 38 citations

Follicle-Stimulating Hormone Regulation of Androgen-Binding Protein Messenger RNA in Sertoli Cell Cultures

1990 • 38 citations

Endocytosis of Human Sex Steroid‐binding Protein in Monkey Germ Cells

1991 • 37 citations

Human Testicular Androgen-Binding Protein Shares Immunodeterminants with Serum Testosterone-Estradiol-Binding Globulin^*

1984 • 37 citations

Total Estradiol, Free Estradiol, Sex Hormone-Binding Globulin, and the Fraction of Estradiol Bound to Sex Hormone-Binding Globulin in Human Follicular Fluid*

1986 • 37 citations

Investigations on the Relationship between Sperm Fertilizing Ability and Androgen-Binding Protein in the Restricted Rat^*

1984 • 37 citations

Localization of androgen-binding protein in proliferating Sertoli cells in culture.

1980 • 36 citations

Origin of the heavy and light protomers of androgen-binding protein from the rat testis.

1981 • 35 citations

A Proposed Consensus Steroid-Binding Sequence—a Reply

1989 • 35 citations

Proteins in luminal fluid of the ram excurrent ducts: changes in composition and evidence for differential endocytosis.

1990 • 35 citations

Sex steroid binding protein (SBP) receptors in estrogen sensitive tissues

1991 • 35 citations

Binding of human sex hormone-binding globulin-androgen complexes to the placental syncytiotrophoblast membrane

1990 • 35 citations

Human Testosterone-Binding Globulin Is a Dimer Composed of Two Identical Protomers that Are Differentially Glycosylated*

1989 • 35 citations

Androgen Transport Proteins: Physical Properties, Hormonal Regulation, and Possible Mechanism of TeBG and ABP Action

1981 • 35 citations

Sex steroid-binding protein interacts with a specific receptor on human premenopausal endometrium membrane: modulating effect of estradiol☆

1991 • 34 citations

Identification of lysine 134 in the steroid-binding site of the sex steroid-binding protein of human plasma.

1990 • 34 citations

Molecular analyses of a human sex hormone-binding globulin variant: evidence for an additional carbohydrate chain

1992 • 34 citations

Influence of Purified Plasma Proteins on Testosterone Uptake and Metabolism by Normal and Hyperplastic Human Prostate in “Constant-Flow Organ Culture”

1976 • 33 citations

Physiology of the Testosterone‐Binding Globulin in Man

1988 • 33 citations

Binding of sex-hormone-binding globulin (SHBG) to testicular membranes and solubilized receptors

1992 • 32 citations

Subunits of human sex hormone binding globulin. Interindividual variation in size.

1987 • 32 citations

Demonstration and Partial Characterization of a Rabbit Serum Protein Which Binds Testosterone and Dihydrotestosterone

1973 • 32 citations

Are Corticosteroid‐Binding Globulin and Sex Hormone‐Binding Globulin Hormones?a

1988 • 32 citations

Expression and Differential Glycosylation of Human Sex Hormone-Binding Globulin by Mammalian Cell Lines

1991 • 32 citations

Investigations on the Relationship between Sperm Fertilizing Ability and Androgen-Binding Protein in the Hypophysectomized, pregnenoloneenolone-Injected Rat^*

1984 • 31 citations

Fluorescence investigation of the sex steroid binding protein of rabbit serum: steroid binding and subunit dissociation

1990 • 31 citations

3 Changing concepts of active androgens in blood

1986 • 31 citations

The membrane receptor for sex steroid binding protein is not ubiquitous

1992 • 31 citations

The serum steroid transport proteins: Biochemistry and clinical significance

1984 • 31 citations

Monospecific antibodies to the sex steroid-binding protein (SBP) of human and rabbit sera: Cross-reactivity with other species

1978 • 30 citations

Effects of hormones on SBP mRNA levels in human cancer cells

1991 • 29 citations

Affinity Labeling, Molecular Cloning, and Comparative Amino Acid Sequence Analyses of Sex Steroid‐Binding Protein of Plasma

1988 • 29 citations

Receptor for sex steroid-binding protein of endometrium membranes: solubilization, partial characterization, and role of estradiol in steroid-binding protein-soluble receptor interaction

1992 • 29 citations

A novel steroid-binding protein in the testis of the dogfish Squalus acanthias

1987 • 29 citations

FSH and Androgen Regulation of Sertoli Cell Function in the Immature Rat

1978 • 28 citations

The Production of Androgen Binding Protein by Sertoli Cells

1974 • 28 citations

In vivo and in vitro studies on sex steroid binding protein (SBP) regulation in rainbow trout (oncorhynchus mykiss): Influence of sex steroid hormones and of factors linked to growth and metabolism

1991 • 27 citations

The epidemiology and function of sex hormone-binding globulin.

1988 • 27 citations

Plasma Protein‐Mediated Transport of Steroid and Thyroid Hormones

1988 • 27 citations

Effects of thyroid hormone on sex hormone-binding globulin gene expression in human cells.

1992 • 27 citations

The Microheterogeneity of Rat Androgen-Binding Protein from the Testis, Rete Testis Fluid, and Epididymis, as Demonstrated by Immunoelectrophoresis and Photoaffinity Labeling*

1981 • 26 citations

Photoaffinity labelled rat androgen-binding protein and human sex hormone steroid-binding protein bind specifically to rat germ cells

1992 • 26 citations

Complete enzymatic deglycosylation of native sex steroid‐binding protein (SBP or SHBG) of human and rabbit plasma: Effect on the steroid‐binding activity

1992 • 26 citations

Cloning of the cDNA encoding human histidine decarboxylase from an erythroleukemia cell line and mapping of the gene locus to chromosome 15

1991 • 26 citations

Human liver nuclear transcortin its postulated role in glucocorticoid regulation of genetic activity

1974 • 26 citations

Hormonal Regulation of Androgen-Binding Protein in Hypophysectomized Rats*

1978 • 25 citations

Biphasic effect of testosterone propionate on sertoli cell secretory function

1976 • 25 citations

Regulation of SBP synthesis in human cancer cell lines by steroid and thyroid hormones

1989 • 25 citations

Structure/function analyses of human sex hormone‐binding globulin by site‐directed mutagenesis

1992 • 24 citations

The microheterogeneity of androgen-binding protein in rat serum and epididymis is due to differences in glycosylation of their subunits.

1988 • 24 citations

Endocytosis of Androgen‐Binding Protein, Cluster in, and Transferrin in the Efferent Ducts and Epididymis of the Ram

1991 • 24 citations

Distribution of testosterone-estradiol binding globulin (TeBG) in the higher vertebrates.

1977 • 23 citations

An enzyme-immunoassay (ELISA) for the Sex Steroid-Binding Protein (SBP) of human serum

1982 • 23 citations

Dexamethasone suppresses sex-hormone binding globulin

1988 • 23 citations

Proteins in Luminal Fluid of the Ram Excurrent Ducts: Change in Composition and Evidence for Differential Endocytosis

1990 • 23 citations

Testosterone binding in human plasma.

1968 • 23 citations

THE SECRETION OF ANDROGEN‐BINDING PROTEIN AND OTHER PROTEINS BY RAT SERTOLI CELLS IN CULTURE: A STRUCTURAL AND ELECTROPHORETIC STUDY*

1982 • 22 citations

Genetic variation of human sex hormone-binding globulin: evidence for a worldwide bi-allelic gene.

1992 • 22 citations

Purification of the sex steroid-binding protein from common carp (Cyprinus carpio) plasma

1992 • 21 citations

Size isomers of testosterone-estradiol-binding globulin exist in the plasma of individual men and women

1985 • 21 citations

Analysis of the Steroid Binding Domain of Rat Androgen-Binding Protein*

1991 • 21 citations

The receptor for human sex steroid binding protein (SBP) is expressed on membranes of neoplastic endometrium

1992 • 20 citations

Analysis of the oligosaccharides on androgen-binding proteins: Implications concerning their role in structure/function relationships

1991 • 19 citations

Immunohistochemical detection of a sex hormone binding globulin like antigen in tissue sections of normal human prostate, benign prostatic hypertrophy and normal human endometrium

1988 • 19 citations

An antiserum specific for human sex steroid‐binding plasma protein (SBP)

1977 • 19 citations

Histidine 235 of human sex hormone-binding globulin is the covalent site of attachment of the nucleophilic steroid derivative, 17 beta-bromoacetoxydihydrotestosterone.

1990 • 19 citations

Evidence for an androgen binding protein in the testis of a teleost fish (Salmo gairdneri R.): A potential marker of sertoli cell function

1989 • 18 citations

THE INFLUENCE OF SERUM ON THE UPTAKE, CONVERSION AND ACTION OF DIHYDROTESTOSTERONE IN RAT PROSTATE GLANDS IN ORGAN CULTURE

1975 • 18 citations

Effect of testosterone propionate on ABP levels in rats hypophysectomised at different ages using individual sampling

1977 • 18 citations

Rates of dissociation of sex steroid hormones from human sex hormone-binding globulin: A reassessment

1990 • 18 citations

Binding of the Photoaffinity Ligand 17β-Hydroxy-4,6- Androstadien-3-One to Rat Androgen-Binding Protein: Comparison with the Binding of 17β-Hydroxy-5α- Androstan-3-One*

1980 • 18 citations

Genetic mapping of the gene for androgen-binding protein/sex hormone-binding globulin to mouse Chromosome 11

1991 • 18 citations

Internalization of human sex steroid-binding protein in the monkey epididymis

1990 • 18 citations

Selective delivery of sex steroid hormones to tissues by albumin and by sex hormone-binding globulin.

1988 • 18 citations

Subunit Structure of Sex-Steroid-Binding Plasma Proteins from Man, Cattle, Dog, and Rabbit

1984 • 17 citations

The binding of testosterone to different serum proteins: A comparative study

1972 • 17 citations

Intraluminal Androgen Binding Protein Alters 3H-Androgen Uptake by Rat Epididymal Tubules in Vitro1

1990 • 16 citations

Localization of the steroid‐binding site of the human sex steroid‐binding protein of plasma (SBP or SHBG) by site‐directed mutagenesis

1992 • 16 citations

Effects of thyroid hormone on sex hormone-binding globulin gene expression in human cells

1992 • 16 citations

Detection of genetic variation with radioactive ligands. V. Genetic variants of testosterone-binding globulin in human serum.

1983 • 16 citations

Mutagenesis of essential functional residues of rat androgen-binding protein/sex hormone-binding globulin.

1993 • 15 citations

The genes for SHBG/ABP and the SHBG-like region of vitamin K-dependent protein S have evolved from a common ancestral gene

1991 • 15 citations

Half-life of plasma sex steroid-binding protein (SBP) in the primate

1989 • 15 citations

Mammalian expression of the human sex steroid‐binding protein of plasma (SBP or SHBG) and testis (ABP) Characterization of the recombinant protein

1992 • 14 citations

Monoclonal Antibodies to Rat Androgen-Binding Protein Recognize Both of Its Subunits and Cross-React with Rabbit and Human Testosterone-Binding Globulin*

1988 • 13 citations

Immunohistochemical Demonstration of Androgen-Binding Protein in the Rat Prostatic Gland1

1991 • 13 citations

Genetic variation of human sex hormone-binding globulin: evidence for a worldwide bi-allelic gene

1992 • 12 citations

Effects of Chronic Infusions of Sex Steroid-Binding Protein on the Testosterone-Mediated Inhibition of Gonadotropin Secretion and Maintenance of Sex Accessory Glands in Male Rats*

1988 • 12 citations

Genetic polymorphism of the human sex hormone-binding globulin: Evidence of an isoelectric focusing variant with normal androgen-binding affinities

1990 • 11 citations

Hormone-associated variation of the glycan microheterogeneity pattern of human sex steroid-binding protein (hSBP)

1991 • 11 citations

Mutagenesis of essential functional residues of rat androgen-binding protein/sex hormone-binding globulin

1993 • 11 citations

The role of asparagine-linked oligosaccharides in the subunit structure, steroid binding, and secretion of androgen-binding protein.

1992 • 10 citations

Developmental Pattern of Androgen-Binding Protein Secretion During the Critical Period of Sexual Differentiation

1985 • 10 citations

Comparison of rabbit androgen binding protein with testosterone estradiol binding globulin—I. Physical and chemical properties

1984 • 10 citations

Structure of Asparagine-Linked Oligosaccharides on Human and Rabbit Testosterone-Binding Globulin1

1990 • 10 citations

[Purification and physico-chemical properties of the sex steroid-binding globulin of human blood].

1983 • 9 citations

Effect of testosterone on regulation of the level of sex steroid-binding protein mRNA in monkey (Macaca fascicularis) liver

1990 • 9 citations

Reduction of testosterone availability to 5α‐reductase by human sex hormone‐binding globulin in the rat ventral prostate gland in vivo

1990 • 9 citations

Sex steroid-binding protein: Identification and comparison of the primary product following cell-free translation of human and monkey (Macaca fascicularis) liver RNA

1989 • 9 citations

Dimerization of shbg by gelatin and dithiothreitol. Implications for the measurement of SHBG binding capacity in human serum

1987 • 8 citations

Free Fatty Acid-Induced Alterations in the Steroid-Binding Properties of Rat Androgen-Binding Protein

1993 • 8 citations

Binding of testosterone in mouse plasma.

1976 • 7 citations

Analysis of the Oligosaccharides on Rat Androgen-Binding Protein Using Serial Lectin Chromatography1

1990 • 6 citations

Comparison of rabbit epididymal androgen binding protein and serum testosterone estradiol binding globulin—II. Immunological properties

1986 • 6 citations

Demonstration of Androgen-Binding Protein Gene Expression in Primary Neuronal and Astrocyte Cultures

1993 • 6 citations

The apparent molecular weight of androgen-binding protein (ABP) in the blood of immature rats differs from that of ABP in the epididymis

1987 • 5 citations

The Microheterogeneity of Rabbit Testosterone-Binding Globulin is Due to Differential Glycosylation of its Single Protomer1

1989 • 4 citations

Different Mechanisms are Responsible for 3H-Androgen Movement Across the Rat Seminiferous and Epididymal Epithelia in Vivo1

1991 • 4 citations

137. Purification of SBP (“sex steroid binding plasma protein”) from human pregnancy plasma by affinity chromatography

1974 • 4 citations

Precision of assays for sex-hormone-binding globulin: an I-IRMA kit and two Eu-IFMA kits compared.

1987 • 3 citations

Identification of the primary translation product of the sex steroid-binding protein from monkey liver mRNA in a cell-free system

1988 • 3 citations

Hormonal Communicating Events in the Testis

1989 • 2 citations

Measurement of steroid-binding proteins by steroid binding

1986 • 2 citations

Deleted Work

1955 • 0 citations