Regulation of Gamma-Glutamyl Transpeptidase Catalytic Activity and Protein Level in the Initial Segment of the Rat Epididymis by Testicular Factors: Role of Basic Fibroblast Growth Factor1

The Physiology of Reproduction

1988 • 7,765 citations

Deletion of steroid 5α-reductase 2 gene in male pseudohermaphroditism

1991 • 641 citations

The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites.

1990 • 450 citations

γ-Glutamyl transpeptidase: catalytic, structural and functional aspects

1981 • 442 citations

Reversible staining and peptide mapping of proteins transferred to nitrocellulose after separation by sodium dodecylsulfate-polyacrylamide gel electrophoresis

1986 • 408 citations

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

1996 • 367 citations

Gamma-glutamyl transpeptidase – its role in hepatocarcinogenesis

1985 • 313 citations

The structure and fuction of the Epididymis. 1. The histology of the Rat Epididymis.

1957 • 299 citations

Regulation of Epididymal Epithelial Cell Functions1

1995 • 266 citations

Extracellular glutathione is a source of cysteine for cells that express .gamma.-glutamyl transpeptidase

1993 • 265 citations

PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes.

1989 • 197 citations

Failure of Exogenous Androgen to Prevent Regression of the Initial Segments of the Rat Epididymis after Efferent Duct Ligation or Orchidectomy1

1979 • 190 citations

The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades.

1996 • 143 citations

Specialized Gene Expression in the Epididymis

1995 • 138 citations

Molecular cloning and nucleotide sequence of rat kidney gamma-glutamyl transpeptidase cDNA.

1986 • 137 citations

The epididymis as protector of maturing spermatozoa

1995 • 121 citations

Basic fibroblast growth factor (bFGF) gene expression and protein production during pubertal development of the seminiferous tubule: follicle-stimulating hormone-induced Sertoli cell bFGF expression.

1992 • 120 citations

Characteristics of Testicular Spermatozoa and the Fluid which Transports them into the Epididymis

1969 • 119 citations

Basic fibroblast growth factor is a testicular germ cell product which may regulate Sertoli cell function.

1993 • 97 citations

Spermatozoa Are Exposed to a Complex Microenvironment as They Traverse the Epididymis^a

1991 • 96 citations

Identification of Epidermal Growth Factor-Like Activity in Human Male Reproductive Tissues and Fluids*

1984 • 95 citations

A Spermatozoa-Associated Factor Regulates Proenkephalin Gene Expression in the Rat Epididymis

1990 • 95 citations

The Testicular and Epididymal Luminal Amino Acid Microenvironment in the Rat

1990 • 94 citations

Isolation and partial characterization of basic fibroblast growth factor from bovine testis

1987 • 93 citations

A major mRNA of the human epididymal principal cells, HE5, encodes the leucocyte differentiation CDw52 antigen peptide backbone

1993 • 89 citations

Concentrations of Seven Elements in the Intraluminal Fluids of the Rat Seminiferous Tubules, Rete Testis, and Epididymis1

1980 • 89 citations

Inhibin in individual ovine follicles in relation to diameter and atresia

1983 • 87 citations

Elucidation of a signaling pathway induced by FGF-2 leading to uPA gene expression in NIH 3T3 fibroblasts.

1995 • 82 citations

gamma-Glutamyl transpeptidase: a single copy gene in the rat and a multigene family in the human genome.

1988 • 81 citations

Expression of multiple gamma-glutamyl transpeptidase messenger ribonucleic acid transcripts in the adult rat epididymis is differentially regulated by androgens and testicular factors in a region-specific manner.

1994 • 74 citations

A Rat Sertoli Cell Factor Similar to Basic Fibroblast Growth Factor Increases c-fos Messenger Ribonucleic Acid in Cultured Sertoli Cells

1989 • 74 citations

Regional Differences in Luminal Fluid Polypeptides of the Rat Testis and Epididymis Revealed by Two‐dimensional Gel Electrophoresis

1985 • 71 citations

SEQUENCES OF INTEREST: Molecular Cloning of Complementary Deoxyribonucleic Acid for an Androgen-Regulated Epididymal Protein: Sequence Homology with Metalloproteins

1988 • 70 citations

Presence and Localization of a 30-kDa Basic Fibroblast Growth Factor-Like Protein in Rodent Testes*

1991 • 60 citations

Structure and expression of the rat epididymal secretory protein I gene. An androgen-regulated member of the lipocalin superfamily with a rare splice donor site

1992 • 53 citations

Tissue-specific expression of multiple gamma-glutamyl transpeptidase mRNAs in rat epithelia

1991 • 49 citations

Early effects of efferent ductule ligation on the proximal segment of the rat epididymis

1983 • 47 citations

Endocytosis of androgen-binding protein, clusterin, and transferrin in the efferent ducts and epididymis of the ram.

1991 • 46 citations

Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene

1997 • 46 citations

Identification, Expression, and Regulation of the Transcriptional Factor Polyomavirus Enhancer Activator 3, and its Putative Role in Regulating the Expression of Gamma-Glutamyl Transpeptidase mRNA-IV in the Rat Epididymis1

1997 • 45 citations

Is the Epididymis a Kidney Analogue?

1988 • 43 citations

Glutathione, L‐glutamic acid and γ‐glutamyl transpeptidase in the bull reproductive tissues

1988 • 43 citations

γ-glutamyl transpeptidase and related enzyme activities in the reproductive system of the male rat

1977 • 43 citations

Rete testis fluid contains a growth factor for cultured fibroblasts

1982 • 42 citations

The segment-specific pattern of A-raf expression in the mouse epididymis is regulated by testicular factors.

1995 • 39 citations

Organization of the 5' end of the rat .gamma.-glutamyl transpeptidase gene: structure of a promoter active in the kidney

1991 • 38 citations

Functional characterization of the rat gamma-glutamyl transpeptidase promoter that is expressed and regulated in the liver and hepatoma cells.

1994 • 38 citations

Multiple Forms of Gamma-Glutamyl Transpeptidase Messenger Ribonucleic Acid are Expressed in the Adult Rat Testis and Epididymis1

1994 • 37 citations

Characterization of epidermal growth factor receptor in testis, epididymis and vas deferens of non-human primates

1992 • 36 citations

Basic fibroblast growth factor (bFGF) in rodent testis Presence of bFGF mRNA and of a 30 kDa bFGF protein in pachytene spermatocytes

1992 • 34 citations

Hormonal and paracrine regulation of γ-glutamyl transpeptidase in rat Sertoli cells

1989 • 34 citations

Evidence for an Organ- and Sex-Specific Role of Basic Fibroblast Growth Factor in the Development of the Fetal Mammalian Reproductive Tract*

1991 • 34 citations

Cloning of the mouse gene encoding plasma glutathione peroxidase: organization, sequence and chromosomal localization

1995 • 33 citations

A Growth Factor in Bovine and Human Testes Structurally Related to Basic Fibroblast Growth Factor

1988 • 32 citations

Gamma-Glutamyl Transpeptidase, Glutathione, and L-Glutamic Acid in the Rat Epididymis during Postnatal Development1

1988 • 32 citations

Expression and activity of gamma‐glutamyl transpeptidase in the rat epididymis

1991 • 31 citations

Identification of a second promoter which drives the expression of .gamma.-glutamyl transpeptidase in rat kidney and epididymis

1992 • 28 citations

Distribution of γ-Glutamyl Transpeptidase in Male Reproductive System of Rats and its Age-Related Changes

2009 • 28 citations

Expression of the Rat .gamma.-Glutamyl Transpeptidase Gene from a Specific Promoter in the Small Intestine and in Hepatoma Cells

1994 • 27 citations

Members of the rafgene family exhibit segment‐specific patterns of expression in mouse epididymis

1993 • 27 citations

Partial characterization of a unique mitogenic activity secreted by rat Sertoli cells

1991 • 27 citations

Influence of Rete Testis Fluid on the Metabolism of Testosterone by Cultured Principal Cells Isolated from the Proximal or Distal Caput of the Rat Epididymis

1983 • 27 citations

Higher transpeptidation activity and broad acceptor specificity of gamma-glutamyltransferases of tumors.

1976 • 26 citations

Stimulation of protein secretion in the initial segment of the rat epididymis by fluid from the ram rete testis

1990 • 25 citations

THE TIME REQUIRED FOR MATERIALS INJECTED INTO THE RETE TESTIS TO REACH POINTS IN THE CAPUT EPIDIDYMIS OF THE RAT AND OBSERVATIONS ON THE ABSORPTION OF CATIONIC FERRITIN*

1982 • 21 citations

Relationship between submandibular gland epidermal growth factor and spermatogenesis in C3H mice

1994 • 16 citations

γ‐Glutamyl transpeptidase in rat epididymis: effects of castration, hemicastration and efferent duct ligation

1989 • 14 citations

Primary sequence of −1436 to +53 bp of the rat preproenkephalin gene putative Z-DNA and regulatory motifs

1992 • 12 citations

Basic Fibroblast Growth Factor-Like Substance in Nuclei of Male Germ Cells Undergoing Meiosis

1991 • 12 citations

Growth factor activity in luminal fluids from the male reproductive tract of the ram, rat, tammar wallaby (Macropus eugenii) and Japanese quail (Coturnix coturnix japonica)

1989 • 8 citations

The Role of Basic Fibroblast Growth Factor in Prenatal Development in the Rat^a

1991 • 3 citations