Cellular Biology and Biochemistry of the Retinoids

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Epidermal Growth Factor

1979 • 2,964 citations

The pharmacological basis of therapeutics

1981 • 2,853 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

TISSUE CHANGES FOLLOWING DEPRIVATION OF FAT-SOLUBLE A VITAMIN

1925 • 1,630 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Fibronectins—adhesive glycoproteins of cell surface and blood

1978 • 1,418 citations

Phorbol diester receptor copurifies with protein kinase C.

1983 • 1,185 citations

Normal genetically mosaic mice produced from malignant teratocarcinoma cells.

1975 • 1,175 citations

Effects of vitamin A and its analogs (retinoids) on normal and neoplastic cells

1980 • 1,094 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Differentiation of mouse myeloid leukemia cells induced by 1 alpha,25-dihydroxyvitamin D3.

1981 • 1,025 citations

Calmodulin

1980 • 982 citations

Female Steroid Hormones and Target Cell Nuclei

1974 • 946 citations

Dual control of cell growth by somatomedins and platelet-derived growth factor.

1979 • 926 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

Hormonal induction of differentiation in teratocarcinoma stem cells: Generation of parietal endoderm by retinoic acid and dibutyryl cAMP

1980 • 803 citations

Role of retinoids in differentiation and carcinogenesis.

1983 • 780 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 779 citations

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS.

1964 • 773 citations

Comparative Aspects of Glycoprotein Structure

1976 • 767 citations

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

1981 • 756 citations

Cell surface proteins and malignant transformation

1976 • 713 citations

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

1977 • 695 citations

The Role of Polyprenol-Linked Sugars in Glycoprotein Synthesis

1976 • 680 citations

The biochemistry of glycoproteins and proteoglycans

1980 • 651 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1982 • 630 citations

Normal functional characteristics of cultured human promyelocytic leukemia cells (HL-60) after induction of differentiation by dimethylsulfoxide.

1979 • 602 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

Plasminogen activator in early embryogenesis: Enzyme production by trophoblast and parietal endoderm

1976 • 590 citations

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

1982 • 570 citations

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

1981 • 566 citations

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1982 • 540 citations

Terminal differentiation of cultured human epidermal cells

1977 • 521 citations

THE EFFECT OF CELLS TRANSFERRED INTO THE MOUSE BLASTOCYST ON SUBSEQUENT DEVELOPMENT

1974 • 512 citations

Morphogenesis of malformations in hamsters caused by retinoic acid: Relation to dose and stage at treatment

1972 • 501 citations

Growth Factors in Mammalian Cell Culture

1976 • 483 citations

1α,25-Dihydroxyvitamin D3 induces differentiation of human myeloid leukemia cells

1981 • 460 citations

Metaplasia produced in cultures of chick ectoderm by high vitamin A

1953 • 454 citations

THE BIOLOGICAL FUNCTION OF VITAMIN A ACID

1960 • 453 citations

Ovarian plasminogen activator: Relationship to ovulation and hormonal regulation

1975 • 440 citations

Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro

1974 • 437 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Cell interactions modulate embryonal carcinoma cell differentiation into parietal or visceral endoderm

1981 • 384 citations

Retinoic Acid-Induced Growth Inhibition and Morphologic Differentiation of Human Neuroblastoma Cells In Vitro<xref ref-type="fn" rid="fn2">2</xref>

1982 • 384 citations

Structures and organization of cell surface glycolipids dependency on cell growth and malignant transformation

1975 • 382 citations

Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

1983 • 381 citations

The role of lipid intermediates in the glycosylation of proteins in the eucaryotic cell

1979 • 378 citations

Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells

1976 • 374 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 368 citations

Specific binding of phorbol ester tumor promoters

1980 • 364 citations

Molecular Actions and Targets for Cancer Chemotherapeutic Agents

1981 • 361 citations

Tumor-Promoting Phorbol Esters Inhibit Binding of Epidermal Growth Factor to Cellular Receptors

1978 • 355 citations

Serum contains a platelet-derived transforming growth factor.

1982 • 330 citations

Epidermal growth factor. Relationship between receptor regulation and mitogenesis in 3T3 cells.

1978 • 324 citations

Tumour promotor induces plasminogen activator

1976 • 316 citations

Polyamines in Biomedical Research

1981 • 311 citations

Polyamines as physiological substrates for transglutaminases.

1980 • 310 citations

Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid

1973 • 287 citations

Expression of a Cellular Oncogene During Liver Regeneration

1983 • 281 citations

Epidermal growth factor inhibits growth of A431 human epidermoid carcinoma in serum-free cell culture.

1982 • 280 citations

Retinoic acid-binding protein in rat tissue. Partial purification and comparison to rat tissue retinol-binding protein.

1975 • 262 citations

Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen.

1979 • 259 citations

Cultured epithelial cells of cornea, conjunctiva and skin: absence of marked intrinsic divergence of their differentiated states

1977 • 249 citations

Dolichol Monophosphate Glucose: An Intermediate in Glucose Transfer in Liver

1970 • 247 citations

Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma.

1980 • 242 citations

Experimental production of congenital malformations in strains of inbred mice by maternal treatment with hypervitaminosis A.

1961 • 235 citations

Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.

1977 • 234 citations

TERATOGENIC ACTIVITY OF RETINOIC ACID

1967 • 233 citations

Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells.

1982 • 224 citations

Possible role of retinoic acid binding protein in retinoid stimulation of embryonal carcinoma cell differentiation

1979 • 220 citations

Induction of differentiation of the human histiocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3':5'-monophosphate-inducing agents.

1982 • 219 citations

In Vitro Binding of Retinol to Rat-Tissue Components

1973 • 217 citations

The Direct Involvement of Vitamin A in Glycosyl Transfer Reactions of Mammalian Membranes

1978 • 212 citations

Hematopoietic studies in vitamin A deficiency

1978 • 209 citations

Preparation of delipidized serum protein for use in cell culture systems

1976 • 191 citations

Molecular Interrelations of Nutrition and Cancer

1982 • 190 citations

Different susceptibilities of human melanoma and breast carcinoma cell lines to retinoic acid-induced growth inhibition.

1979 • 190 citations

Constitutive uncoupling of pathways of gene expression that control growth and differentiation in myeloid leukemia: a model for the origin and progression of malignancy.

1980 • 189 citations

Prostaglandins and cancer: An update

1974 • 188 citations

Retinoids specifically enhance the number of epidermal growth factor receptors

1980 • 187 citations

Relation of protein synthesis and transglutaminase activity to formation of the cross-linked envelope during terminal differentiation of the cultured human epidermal keratinocyte

1978 • 186 citations

Priming of human myeloid leukemic cell lines HL-60 and U-937 with retinoic acid for differentiation effects of cyclic adenosine 3':5'-monophosphate-inducing agents and a T-lymphocyte-derived differentiation factor.

1982 • 181 citations

Inhibitory Effects of Retinoic Acid or Retinyl Acetate on the Growth of Untransformed, Transformed, and Tumor Cells In Vitro 2

1977 • 180 citations

Retinoic acid enhances colony-stimulating factor-induced clonal growth of normal human myeloid progenitor cells in vitro*1

1982 • 178 citations

Relationships between structure and activity of retinoids

1976 • 176 citations

Replacement of serum by insulin and transferrin supports growth and differentiation of the human promyelocytic cell line, HL-60

1980 • 170 citations

Cellular tumorigenicity in nude mice. Test of associations among loss of cell-surface fibronectin, anchorage independence, and tumor-forming ability.

1979 • 170 citations

Stimulation of differentiation of several murine embryonal carcinoma cell lines by retinoic acid

1979 • 165 citations

Inhibition by Retinoic Acid of Collagenase Production in Rheumatoid Synovial Cells

1980 • 164 citations

Retroviruses and Cancer Genes

1982 • 161 citations

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by vitamin A analogs (retinoids).

1978 • 160 citations

Control of Phenotypic Expresssion of Cultured Melanoma Cells by Melanocyte Stimulating Hormones

1973 • 160 citations

The Culture of Vertebrate Embryos.

1967 • 160 citations

Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts

1976 • 159 citations

Inhibition of limb chondrogenesis in vitro by vitamin A: Alterations in cell surface characteristics

1978 • 159 citations

Characterization of the action of retinoids on mouse fibroblast cell lines

1979 • 157 citations

Reversible inhibition by retinoids of 3-methylcholanthrene-induced neoplastic transformation in C3H/10T1/2 clone 8 cells.

1979 • 154 citations

All-trans-retinoic acid: measurement of reference values in human serum by high performance liquid chromatography

1982 • 153 citations

Mechanisms of Tumor Promotion and Cocarcinogenesis

1979 • 142 citations

Modulation and mediation of cancer by vitamins

1983 • 139 citations

Collagenase production by synovial fibroblasts treated with phorbol myristate acetate

1979 • 139 citations

Epidermal growth factor receptors increase during the differentiation of embryonal carcinoma cells

1979 • 137 citations

Acute myelocytic leukemia in adults

1972 • 137 citations

Differential effects of sodium butyrate, dimethyl sulfoxide, and retinoic acid on membrane-associated antigen, enzymes, and glycoproteins of human rectal adenocarcinoma cells.

1982 • 134 citations

Binding of Retinoids to Human Breast Cancer Cell Lines and their Effects on Cell Growth

1980 • 133 citations

Surfaces of Normal and Malignant Cells

1980 • 133 citations

Characterization of the Inhibitory Effects of Retinoids on the In Vitro Growth of Two Malignant Murine Melanomas2

1978 • 132 citations

Plasminogen activator in chick fibroblasts: Induction of synthesis by retinoic acid; synergism with viral transformation and phorbol ester

1978 • 132 citations

Retinoic acid enhances growth of human early erythroid progenitor cells in vitro.

1982 • 130 citations

Regulation by Vitamin A of Envelope Cross-Linking in Cultured Keratinocytes Derived from Different Human Epithelia

1982 • 129 citations

Retinoids block phenotypic cell transformation produced by sarcoma growth factor

1978 • 127 citations

Comparison of growth in vitro and in vivo of post-implantation rat embryos

1976 • 127 citations

Plasma Concentrations of Immunoreactive Human Epidermal Growth Factor (Urogastrone) in Man*

1980 • 127 citations

Retinoic acid: A binding protein in chick embryo metatarsal skin

1974 • 126 citations

A vitamin A analogue inhibits radiation-induced oncogenic transformation

1978 • 126 citations

CELLULAR TRANSGLUTAMINASE, GROWTH, AND TRANSFORMATION

1978 • 124 citations

Interaction of the retinol/cellular retinol-binding protein complex with isolated nuclei and nuclear components.

1981 • 123 citations

Test for Malignant Transformation of Rat Liver Cells in Culture: Cytology, Growth in Soft Agar, and Production of Plasminogen Activator

1977 • 123 citations

Biosynthesis of a Fucose-containing Glycopeptide from Rat Small Intestine in Normal and Vitamin A-deficient Conditions

1970 • 122 citations

Stimulation of melanogenesis in a human melanoma cell line by retinoids.

1980 • 121 citations

Transglutaminase activity in normal and transformed cells.

1977 • 121 citations

Induction of differentiation of cultured human promyelocytic leukemia cells by retinoids

1980 • 119 citations

Retinol induces density-dependent growth inhibition and changes in glycolipids and LETS

1978 • 118 citations

Loss of epidermal growth factor requirement and malignant transformation

1979 • 117 citations

Phorbol ester tumor promoters induce epidermal transglutaminase activity

1980 • 117 citations

Vitamin A and Protein Synthesis by Rat Intestinal Mucosa

1969 • 115 citations

Cellular retinol-binding protein allows specific interaction of retinol with the nucleus in vitro.

1979 • 115 citations

Inhibition of human melanoma colony formation by retinoids.

1979 • 114 citations

The effects of retinoids on neutrophil functions in vitro

1982 • 114 citations

Polyamine and differentiation: induction of ornithine decarboxylase by parathyroid hormone is a good marker of differentiated chondrocytes.

1980 • 112 citations

Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis

1976 • 112 citations

Ornithine Decarboxylase: Essential in Proliferation But Not Differentiation of Human Promyelocytic Leukemia Cells

1982 • 110 citations

Participation of myeloid leukaemic cells injected into embryos in haematopoietic differentiation in adult mice

1982 • 110 citations

Retinoic acid: An endogenous compound of human blood. Unequivocal demonstration of endogenous retinoic acid in normal physiological conditions

1979 • 110 citations

Teratocarcinomas and Other Neoplasms as Developmental Defects in Gene Expression

1981 • 109 citations

Cellular Vitamin A Binding Proteins

1979 • 107 citations

The Influence of a Hypervitaminosis on the Effect of 20-Methylcholanthrene on Mouse Prostate Glands Grown In Vitro

1955 • 106 citations

Structure-activity relationships of a new series of retinoidal benzoic acid derivatives as measured by induction of differentiation of murine F9 teratocarcinoma cells and human HL-60 promyelocytic leukemia cells.

1983 • 105 citations

The biological activity of retinoic acid in the domestic fowl and the effects of vitamin A deficiency on the chick embryo

1969 • 103 citations

Regulation by vitamin A of envelope cross-linking in cultured keratinocytes derived from different human epithelia.

1982 • 103 citations

Enhanced cellular fibronectin accumulation in chondrocytes treated with vitamin A

1979 • 101 citations

Studies on the effect of retinoids on the differentiation of teratocarcinoma stem cells in vitro and in vivo

1980 • 101 citations

The Function of Vitamin A: Current Concepts

1983 • 100 citations

Evidence for non-spliced SV40 RNA in undifferentiated murine teratocarcinoma stem cells

1979 • 98 citations

Effect of retinoic acid treatment of F9 embryonal carcinoma cells on the activity and distribution of cyclic AMP-dependent protein kinase.

1982 • 97 citations

Mesenchymal Cells from the Human Embryonic Palate Are Highly Responsive to Epidermal Growth Factor

1981 • 97 citations

Retinoids as well as tumour promoters enhance deacylation of cellular lipids and prostaglandin production in MDCK cells

1978 • 95 citations

Growth and differentiation of embryonal carcinoma cell line F9 in defined media.

1980 • 95 citations

Retinoid inhibition of superoxide anion radical production by human polymorphonuclear leukocytes stimulated with tumor promoters

1980 • 95 citations

Retinoic acid induces transglutaminase activity but inhibits cornification of cultured epidermal cells.

1982 • 93 citations

Characterization of the effects of different retinoids on the growth and differentiation of a human melanoma cell line and selected subclones.

1980 • 92 citations

Mechanism of vitamin A action. Gene expression in retinol-deficient rats.

1982 • 90 citations

Induction of neural-like cells and acetylcholinesterase activity in cultures of F9 teratocarcinoma treated with retinoic acid and dibutyryl cyclic adenosine monophosphate

1980 • 87 citations

Preadipocytes possess cellular retinoid binding proteins and their differentiation is inhibited by retinoids

1980 • 86 citations

Characterization of cytosolic calcium-activated phospholipid-dependent protein kinase activity in embryonal carcinoma cells. Effect of retinoc acid-induced differentiation of F9 cells to parietal endoderm.

1983 • 86 citations

Differential binding to soluble nuclear receptors and effects on cell viability of retinol and retinoic acid in cultured retinoblastoma cells

1977 • 85 citations

Polyamines as chemical markers of malignancy.

1976 • 85 citations

Retinoic acid increases cyclic AMP-dependent protein kinase activity in murine melanoma cells.

1980 • 85 citations

Retinoic acid-induced differentiation of F9 embryonal carcinoma cells

1981 • 85 citations

Chondrogenesis and cell proliferation in limb bud cell cultures treated with cytosine arabinoside and vitamin A

1978 • 84 citations

Anti-inflammatory effects of 13-cis-retinoic acid

1981 • 83 citations

Plasminogen activator in chick embryo muscle cells: Induction of enzyme by RSV, PMA and retinoic acid

1978 • 83 citations

Relationships among retinoid structure, inhibition of growth, and cellular retinoic acid-binding protein in cultured S91 melanoma cells.

1980 • 82 citations

Epidermal Growth Factor: Mechanisms of Action

1982 • 81 citations

High-pressure liquid chromatographic determination of 13-cis-retinoic acid and all-trans-retinoic acid in human plasma

1978 • 80 citations

The biosynthesis of a mannolipid that contains a polar metabolite of 15-14C-retinol

1970 • 80 citations

Growth Stimulation of Cultured Postembryonic Epidermal Cells by Vitamin a Acid**From the Department of Dermatology, University of Munich, 8 München 2, Germany

1974 • 80 citations

Retinoid-Induced Adhesion in Cultured, Transformed Mouse Fibroblasts

1979 • 79 citations

Vitamin A-Induced Density-Dependent Inhibition of L-Cell Proliferation2

1977 • 78 citations

Isolation and characterization of mouse mutant embryonal carcinoma cells which fail to differentiate in response to retinoic acid.

1981 • 77 citations

Mechanisms that uncouple growth and differentiation in myeloid leukemia cells: restoration of requirement for normal growth-inducing protein without restoring induction of differentiation-inducing protein.

1982 • 77 citations

Enzymatic synthesis of mannosyl retinyl phosphate from retinyl phosphate and guanosine diphosphate mannose

1975 • 76 citations

Effect of retinoic acid on chondrocyte glycosaminoglycan biosynthsis

1976 • 74 citations

Differentiation as a requirement for simian virus 40 gene expression in F-9 embryonal carcinoma cells.

1979 • 74 citations

Modulation by retinoic acid and corticosteroids of collagenase production by rabbit synovial fibroblasts treated with phorbol myristate acetate or poly(ethylene glycol)

1981 • 73 citations

Retinoic acid and the restoration of anchorage dependent growth to transformed mammalian cells

1978 • 73 citations

Retinoic Acid Delays the Terminal Differentiation of Keratinocytes in Suspension Culture

1981 • 72 citations

DNA-transformed murine teratocarcinoma cells: regulation of expression of simian virus 40 tumor antigen in stem versus differentiated cells.

1980 • 71 citations

The Effect of Vitamin A on Growth and Differentiation of Human Keratinocytes in Vitro

1975 • 70 citations

Elevated levels of cAMP alters the effect of epidermal growth factor in vitro on programmed cell death in the secondary palatal epithelium

1977 • 70 citations

Mode of action of retinol. Involvement in glycosylation reactions of cultured mouse epidermal cells.

1979 • 69 citations

Biosynthetic studies on mannolipids and mannoproteins of normal and vitamin a-depleted hamster livers

1975 • 69 citations

Enhancement of melanotic expression in cultured mouse smelanoma cells by retinoids

1981 • 68 citations

Actions of insulin and vitamin A on Sertoli cells

1980 • 68 citations

Retinoids as regulators of macrophage function.

1980 • 68 citations

Retinoic acid-induced modifications in the growth and cell surface components of a human carcinoma (HeLa) cell line

1980 • 65 citations

Altered glycoprotein synthesis in mouse epidermal cells treated with retinyl acetate in vitro

1974 • 65 citations

Effects of phorbol ester tumor promoters on arachidonic acid metabolism in chick embryo fibroblasts.

1979 • 64 citations

Altered proteoglycan metabolism in mouse limb mesenchyme cell cultures treated with vitamin A

1978 • 64 citations

Glycoproteins from the hamster respiratory tract and their response to vitamin A

1973 • 62 citations

Retinol inhibition of ornithine decarboxylase induction and G1 progression in Chinese hamster ovary cells.

1979 • 62 citations

Chondrocyte metabolism as affected by vitamin A

1975 • 62 citations

Sensitivity of cultured human osteosarcoma and chondrosarcoma cells to retinoic acid.

1982 • 61 citations

Comparison of the effects of retinol and retinoic acid on postimplantation rat embryos in vitro

1977 • 61 citations

In vitro development of oncogenicity in cell lines established from tracheal epithelium preexposed in vivo to 7,12-dimethylbenz(a)anthracene.

1978 • 60 citations

ACTION OF RETINOIDS AND PHORBOL ESTERS ON CELL GROWTH AND THE BINDING OF EPIDERMAL GROWTH FACTOR

1981 • 60 citations

Effects of retinoic acid on the binding and mitogenic activity of epidermal growth factor

1982 • 60 citations

Studies of vitamin A‐induced teratogenesis: Effects on embryonic mesenchyme and epithelium, and on incorporation of H³‐thymidine

1968 • 58 citations

Cell cycle-specific locus of vitamin A inhibition of growth.

1979 • 57 citations

Inhibition of cranial neural crest cell development by vitamin A in the cultured chick embryo

1977 • 56 citations

CHARACTERIZATION OF RETINOIC ACID‐INDUCED ALTERATIONS IN THE PROLIFERATION AND DIFFERENTIATION OF A MURINE AND A HUMAN MELANOMA CELL LINE IN CULTURE*

1981 • 55 citations

Vitamin A and Nuclear RNA Synthesis

1969 • 55 citations

Effects of products from macrophages, blood mononuclear cells and of retinol on collagenase secretion and collagen synthesis in chondrocyte culture

1982 • 54 citations

Retinoids increase transglutaminase activity and inhibit ornithine decarboxylase activity in Chinese hamster ovary cells and in melanoma cells stimulated to differentiate.

1982 • 54 citations

Inhibition of adipose conversion in 3T3‐L2 cells by retinoic acid

1980 • 54 citations

Heterogeneity in growth inhibition by beta-trans-retinoic acid of metastatic B16 melanoma clones and in vivo-selected cell variant lines.

1979 • 54 citations

Comparison of the Level of Cellular Retinoid-Binding Proteins and Susceptibility to Retinoid-Induced Growth Inhibition of Various Neoplastic Cell Lines<xref ref-type="fn" rid="FN2">2</xref>

1980 • 52 citations

STUDIES ON THE MECHANISM OF INDUCTION OF EMBRYONAL CARCINOMA CELL DIFFERENTIATION BY RETINOIC ACID

1981 • 52 citations

Gangliosides and their cell density-dependent changes in control and chemically transformed C3H/10T1/2 cells

1978 • 52 citations

Effect of retinoic acid on cell surface glycopeptides of cultured spontaneously transformed mouse fibroblasts (BALB/c 3T12-3 cells).

1980 • 51 citations

Retinoic acid fails to induce differentiation in human teratocarcinoma cell lines that express high levels of a cellular receptor protein

1983 • 51 citations

Retinoids and phorbol esters alter release of fibronectin from enucleated cells.

1982 • 50 citations

Retinoids enhance mitogenesis by tumour promotor and polypeptide growth factors

1979 • 49 citations

Localization of retinoic acid-binding protein in nuclei and the nuclear uptake of retinoic acid.

1979 • 49 citations

Structure-activity relationships among various retinoids and their ability to inhibit neoplastic transformation and to increase cell adhesion in the C3H/10T1/2 CL8 cell line.

1980 • 49 citations

Survival of rheumatoid synovium implanted into nude mice.

1981 • 49 citations

Reverse phase high-pressure liquid chromatographic separation of retinoids, including retinylphosphate and mannosylretinylphosphate

1980 • 48 citations

Vitamin A Deficiency and the Glycoproteins of Rat Corneal Epithelium

1974 • 48 citations

Differential formation of desmosomes and hemidesmosomes in epidermal cell cultures treated with retinoic acid

1975 • 47 citations

The effect of all-trans-retinoic acid on the synthesis of epidermal cell-surface-associated carbohydrates

1981 • 47 citations

Retinyl acetate modulation of cell growth kinetics and carcinogen-cellular interaction in mouse epidermal cell cultures

1977 • 46 citations

Chemical synthesis of phosphorylated retinoids. Their mannosyl acceptor activity in rat liver membranes.

1977 • 46 citations

Lack of intracellular retinoid-binding proteins in a retinol-sensitive cell line

1982 • 45 citations

Vitamin A and ribonucleic acid synthesis in rat intestine

1970 • 45 citations

Formation and properties of retinylphosphate galactose.

1976 • 45 citations

Effects of retinoic acid on plasminogen activator and mitogenic responses of cultured mouse cells.

1980 • 44 citations

CHANGES IN CELL SURFACE PROTEINS DURING NORMAL AND VITAMIN A‐INHIBITED CHONDROGENESIS IN VITRO

1978 • 44 citations

Retinol-Linked Sugars in Glycoprotein Synthesis

2009 • 44 citations

Alterations in calcitonin and parathyroid hormone responsiveness of adenylate cyclase in F9 embryonal carcinoma cells treated with retinoic acid and dibutyryl cyclic AMP

1981 • 43 citations

Action of epidermal growth factor and retinoids on anchorage-dependent and -independent growth of nontransformed rat kidney cells.

1983 • 43 citations

Retinoic acid-induced alterations of growth and morphology in an established epithelial line

1979 • 42 citations

Polypeptide growth factors: Some structural and mechanistic considerations

1980 • 42 citations

Induction of mouse epidermal ornithine decarboxylase activity and skin tumors by 7, 12-dimethylbenz[a]anthracene: modulation by retinoic acid and 7,8-benzoflavone

1980 • 41 citations

Localization of the Retinol-dependent Fucose-Glycopeptide in the Goblet Cell of the Rat Small Intestine

1971 • 40 citations

Retinyl Acetate: Effect on Cellular Content of RNA in Epidermis in Cell Culture in Chemically Defined Medium

1973 • 40 citations

Identification and characterization of specific changes induced by retinoic acid in cell surface glycoconjugates of S91 murine melanoma cells.

1983 • 40 citations

Effects of retinoids on induction of differentiation of cultured mouse myeloid leukemia cells.

1980 • 40 citations

The stimulation of RNA synthesis and by retinol (vitamin A) in the intestine of vitamin A deficient rats

1967 • 40 citations

RETINOIDS INHIBIT PROMOTER‐DEPENDENT PRENEOPLASTIC PROGRESSION IN MOUSE EPIDERMAL CELL LINES

1981 • 38 citations

A Plasma Glycoprotein Depressed in Vitamin A Deficiency in the Rat: α1-Macroglobulin

1976 • 38 citations

Decrease in collagen production in normal and Rous sarcoma virus-transformed chick embryo fibroblasts induced by phorbol myristate acetate.

1979 • 37 citations

MODULATION OF TERMINAL DIFFERENTIATION AND RESPONSES TO TUMOR PROMOTERS BY RETINOIDS IN MOUSE EPIDERMAL CELL CULTURES

1981 • 37 citations

The Effect of Vitamin A on Cellular Differentiation and Mucous Glycoprotein Synthesis in Long-Term Rat Tracheal Organ Cultures

1979 • 36 citations

Conversion of malignant murine embryonal carcinomas to benign teratomas by chemical induction of differentiation in vivo.

1982 • 36 citations

Variable effects of retinoids on two pigmenting human melanoma cell lines.

1982 • 35 citations

Isolation and analysis of melanoma cell mutants resistant to the antiproliferative action of retinoic acid.

1983 • 35 citations

Rat liver microsomes catalyse mannosyl transfer from GDP-<scp>d</scp>-mannose to retinyl phosphate with high efficiency in the absence of detergents

1981 • 35 citations

Changes in cell surface proteins during differentiation of mouse embryonal carcinoma cells

1981 • 35 citations

Restoration by cyclic AMP of the differentiated phenotype of chondrocytes from de-differentiated cells pretreated with retinoids

1982 • 34 citations

Phenyl Phosphate as a Water-soluble Analog of Dolichyl Phosphate in Microsomal Mannosyltransferase Systems1

1980 • 34 citations

Retinoid metabolism in spontaneously transformed mouse fibroblasts (Balb/c 3T12-3 cells): enzymatic conversion of retinol to anhydroretinol.

1979 • 34 citations

Effect of Retinyl Acetate on Sulfated Glycosaminoglycan Biosynthesis in Dermal and Epidermal Cells in Vitro

1978 • 33 citations

Differential retinoic acid inhibition of ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate and by germicidal ultraviolet light.

1981 • 33 citations

MODULATION OF GLYCOSAMINOGLYCAN BIOSYNTHESIS BY RETINOIDS

1981 • 32 citations

Isolation of methylcholanthrene“initiated” C3H/10T1/2 cells by inhibiting neoplastic progression with retinyl acetate

1982 • 32 citations

Synthesis of retinyl phosphate mannose and dolichyl phosphate mannose from endogenous and exogenous retinyl phosphate and dolichyl phosphate in microsomal fraction. Specific decrease in endogenous retinyl phosphate mannose synthesis in vitamin A deficiency

1982 • 32 citations

Locomotory behavior of limb bud cells

1975 • 31 citations

ANTIPROLIFERATIVE EFFECTS OF RETINOIDS RELATED TO THE CELL CYCLE‐SPECIFIC INHIBITION OF ORNITHINE DECARBOXYLASE

1981 • 31 citations

Comparison of retinoic acid effects on anchorage-dependent growth, anchorage-independent growth and fibrinolytic activity of neoplastic cells

1982 • 30 citations

Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered expression of specific glycoproteins

1981 • 30 citations

Growth inhibitory and stimulatory effects of retinoic acid on murine 3T3 cells.

1982 • 29 citations

Antitumor effects of vitamin A and inhibitors of ornithine decarboxylase in cultured neuroblastoma and glioma cells

1980 • 29 citations

RECENT STUDIES ON THE INVOLVEMENT OF RETINYL PHOSPHATE AS A CARRIER OF MANNOSE IN BIOLOGICAL MEMBRANES

1981 • 27 citations

In vivo synthesis of lipid-linked oligosaccharides in the livers of normal and vitamin A-deficient rats.

1981 • 27 citations

Retinoids inhibit prolactin-induced development of the mammary gland in vitro

1983 • 26 citations

Stimulation of the synthesis of specific glycoproteins in corneal epithelium by vitamin A

1979 • 26 citations

Enhancement in ‘apparent’ membrane microviscosity during differentiation of embryonal carcinoma cells induced by retinoids

1982 • 26 citations

Retinoid effects on cell-cell interactions and growth characteristics of normal and carcinogen-treated C3H/1OT1/2 cells.

1983 • 25 citations

N-(4-hydroxyphenyl)retinamide: a synthetic analog of vitamin A that is a potent inhibitor of prostaglandin biosynthesis

1980 • 24 citations

Action of retinoids on the anchorage-independent growth of normal rat kidney fibroblasts induced by 12-O-tetradecanoylphorbol-13-acetate or sarcoma growth factor.

1983 • 24 citations

Calcium and Cyclic AMP as Synarchic Messengers

1982 • 24 citations

Retinoic acid induces anchorage- and density-dependent growth without restoring normal cytoskeleton, EGF binding, fibronectin content and ODC activity in a retrovirus-transformed mouse cell line*1

1982 • 24 citations

Calcium stimulation of plasminogen activator secretion/production by swiss 3T3 cells.

1977 • 23 citations

Vitamin A-dependent fucose-glycopeptide from rat tracheal epithelium

1974 • 22 citations

VITAMIN A POTENTIATES THE MITOGENIC EFFECT OF EPIDERMAL GROWTH FACTOR IN CULTURES OF NORMAL ADULT HUMAN SKIN FIBROBLASTS

1980 • 22 citations

SPECIFIC AND NONSPECIFIC ALTERATIONS IN MEMBRANE MICROVISCOSITY INDUCED BY RETINOIDS IN EMBRYONAL CARCINOMA AND FIBROBLAST CELLS

1981 • 22 citations

Effects of all-trans-retinoic acid (retinoic acid) and 4-hydroxyphenylretinamide on synovial cells and articular cartilage

1982 • 22 citations

Inhibition by tumor-promoting phorbol esters of procollagen synthesis in promotable JB6 mouse epidermal cells.

1982 • 22 citations

THE INFLUENCE OF RETINOIDS ON POLYAMINE AND DNA SYNTHESIS IN MOUSE EPIDERMIS*

1981 • 22 citations

Effects of retinoic acid on cell proliferation and cell differentiation in a rat tracheal epithelial cell line

1982 • 21 citations

Studies on mannosyl carrier function of retinol and retinoic acid in epithelial and mesenchymal tissues

1982 • 21 citations

Teleocidin B inhibits binding of epidermal growth factor to cellular receptors probably by the same mechanism as phorbol esters

1980 • 21 citations

Retinoic Acid Induces a G1 Cell Cycle Block in HeLa Cells

1980 • 20 citations

Retinoids block ornithine decarboxylase induction in cells treated with the tumor promotor TPA or the peptide growth hormones, EGF and SGF

1980 • 20 citations

Alterations in surface carbohydrates and in some functional properties of liver lysosomal membrane in vitamin A-deficient rat

1980 • 19 citations

Retinoic acid‐promoted expansion of total cellular ATP pools in 3T3 cells can mediate its stimulatory and growth inhibitory effects

1982 • 19 citations

Stimulation of fibronectin production by retinoic acid in mouse skin tumors.

1982 • 19 citations

Effects of exogenous retinol and retinoic acid on the biosynthesis of 14C-mannose labelled glycolipids and glycoproteins in rat liver.

1978 • 19 citations

Effects of retinoic acid on protein synthesis in cultured melanoma cells

1982 • 18 citations

THE BIOSYNTHESIS OF A MANNOLIPID CONTAINING A METABOLITE OF RETINOIC ACID BY 3T12 MOUSE FIBROBLASTS

1981 • 18 citations

THE EFFECT OF VITAMIN A STATUS ON THE DIFFERENTIATION AND FUNCTION OF GOBLET CELLS IN THE RAT INTESTINE*

1981 • 18 citations

EFFECTS OF RETINOIDS ON NEOPLASTIC TRANSFORMATION, CELL ADHESION, AND MEMBRANE TOPOGRAPHY OF CULTURED 10T1/2 CELLS*

1981 • 17 citations

Effect of vitamin A acid on the growth of keratinocytes in culture

1978 • 16 citations

The anomeric configuration of the D-mannosyl retinyl phosphate formed in rat liver microsomes.

1976 • 16 citations

Insulin Binding to Its Receptor: Is the Receptor More Important Than the Hormone?

1981 • 16 citations

Effects of retinoids on normal and neoplastic human cells cultured in vitro.

1980 • 16 citations

Comparative effects of exogenous retinylphosphate and dolichylphosphate on the in vitro mannosylation of glycoproteins

1979 • 16 citations

Vitamin A and galactosyl transferase of tracheal epithelium

1980 • 15 citations

Activation of transglutaminase during cell cycle in CHO cells

1982 • 14 citations

Vitamin A inhibition of keratinization in rat urinary bladder cancer cell line Nara Bladder Tumor No. 2 in meniscus gradient culture.

1975 • 14 citations

Mannosyl transfer from mannosylretinylphosphate to glycoconjugates of rat liver membranes

1980 • 12 citations

Separation of retinol, retinoic acid, mannose, dolichylmannosylphosphate, mannosylretinylphosphate, dolichylphosphate, and retinylphosphate by high-pressure liquid chromatography

1982 • 11 citations

Modulation of Growth, Differentiation, and Mucous Glycoprotein Synthesis by Retlnyl Acetate in Cloned Carcinoma Cell Lines2, 3

1981 • 10 citations

Effects of retinol and retinol palmitate on glycolipid and glycoprotein galactosyltransferase activities of rat liver plasma membranes

1980 • 10 citations

Production of differentiation-inhibiting factor in cultured mouse myeloid leukemia cells treated with retinoic acid.

1981 • 10 citations

GLYCOSYLATION REACTIONS AND TUMOR ESTABLISHMENT: MODULATION BY VITAMIN A*

1981 • 10 citations

FORMATION OF α‐1,2‐ AND α‐1,3‐LINKED MANNOSE DISACCHARIDES FROM MANNOSYL RETINYL PHOSPHATE BY RAT LIVER MEMBRANE ENZYMES*,^†

1981 • 10 citations

VITAMIN A-INDUCED ALTERATIONS IN CORNEAL AND CONJUNCTIVAL EPITHELIAL GLYCOPROTEIN BIOSYNTHESIS

1981 • 9 citations

Effect of the Retinoic Acid Analog Ro 11-1430 on Proteoglycans of Swarm Rat Chondrosarcoma<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1981 • 9 citations

The inhibition by retinoic acid of the biosynthesis of proteoglycans in corneal cell cultures

1980 • 9 citations

Retinoid-Induced Growth Inhibition of Herpesvirus-Transformed Marmoset Lymphoblastoid Cell Lines

1981 • 8 citations

Incorporation of mannose and glucose into prenylphosphate sugars in isolated human platelet membranes

1977 • 8 citations

Antagonistic action of retinoic acid and teleocidin on the proliferation and epidermal growth factor binding of rat hepatoma cells

1981 • 8 citations

Evidence That Vitamin A Is Not Required for the Biosynthesis of Ovalbumin in Chicks

1976 • 7 citations

RETINOIC ACID‐INDUCED ALTERATIONS OF GLYCOSAMINOGLYCAN SYNTHESIS AND DEPOSITION IN B16F10 MELANOMA CELLS*

1981 • 7 citations

Synthesis of retinylphosphate mannose in yeast and its possible involvement in lipid-linked oligosaccharide formation

1983 • 7 citations

BINDING OF RETINOIDS TO HUMAN FIBROBLAST CELL LINES AND THEIR EFFECTS ON CELL GROWTH

1981 • 7 citations

A novel protamine kinase activity in human promyelocytic leukemia cells

1982 • 6 citations

Effect of vitamin A acid on cyclic nucleotides of cultured keratinocytes

1980 • 6 citations

Correlation between activation of quiescent 3T3 cells by retinoic acid and increases in uridine phosphorylation and cellular RNA synthesis.

1982 • 6 citations

Aspergillus niger van Tieghem mannosylation: polyprenylphosphate mannosyltransferase specificity

1982 • 5 citations

VITAMIN A RESPONSE OF TESTICULAR CELLS IN CULTURE

1981 • 4 citations

Keratinization and the effect of vitamin A in aggregates of a squamous carcinoma cell line NBT II

1980 • 4 citations

Effect of Vitamin A Deficiency on Luteinizing Hormone Receptors and Adenosine 3',5'-Monophosphate-Mediated Steroidogenesis in Rat Testicular Tissue

1981 • 3 citations

The polyenic system of retinyl phosphate is required for its mannosyl donor activity but not for acceptor activity

1982 • 2 citations

UNDERGLYCOSYLATION OF RAT SERUM α₁‐MACROGLOBULIN IN VITAMIN A DEFICIENCY*

1981 • 1 citations