Control of messenger RNA stability in higher eukaryotes

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

AU-rich elements: characterization and importance in mRNA degradation

1995 • 1,936 citations

Conserved Structures and Diversity of Functions of RNA-Binding Proteins

1994 • 1,873 citations

mRNA stability in mammalian cells

1995 • 1,258 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro.

1989 • 373 citations

Poly(A), poly(A) binding protein and the regulation of mRNA stability

1989 • 355 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.

1992 • 301 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly(A) tail shortening.

1994 • 290 citations

Translation initiation requires the PAB-dependent poly(A) ribonuclease in yeast

1992 • 212 citations

Multiple regulatory steps control histone mRNA concentrations

1988 • 199 citations

A redox switch and phosphorylation are involved in the post-translational up-regulation of the adenosine-uridine binding factor by phorbol ester and ionophore.

1991 • 184 citations

Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA.

1994 • 125 citations

Sequence-specific endonucleolytic cleavage and protection of mRNA in Xenopus and Drosophila.

1993 • 99 citations

The kinetics of mammalian gene expression

1991 • 91 citations

Human beta-globin mRNAs that harbor a nonsense codon are degraded in murine erythroid tissues to intermediates lacking regions of exon I or exons I and II that have a cap-like structure at the 5′ termini.

1992 • 90 citations

Autogenous Regulation of Histone mRNA Decay by Histone Proteins in a Cell-Free System

1987 • 82 citations

MRNA stability: in trans-it

1992 • 78 citations

AU-A, an RNA-binding activity distinct from hnRNP A1, is selective for AUUUA repeats and shuttles between the nucleus and the cytoplasm

1994 • 75 citations

Endonucleolysis in the turnover of insulin-like growth factor II mRNA.

1992 • 73 citations

In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus

1991 • 71 citations

Mammalian ribonucleotide reductase R1 mRNA stability under normal and phorbol ester stimulating conditions: involvement of a cis-trans interaction at the 3′ untranslated region.

1993 • 67 citations

Purification and Characterization of an Estrogen-regulated Xenopus Liver Polysomal Nuclease Involved in the Selective Destabilization of Albumin mRNA

1995 • 65 citations

Point mutations in the stem-loop at the 3' end of mouse histone mRNA reduce expression by reducing the efficiency of 3' end formation.

1994 • 64 citations

Removal of a 3′ non-coding sequence is an initial step in degradation of groα mRNA and is regulated by interleukin-1

1992 • 64 citations

Purification of a human polyribosome-associated 3‘ to 5‘ exoribonuclease.

1994 • 57 citations

Long-Range RNA Interaction of Two Sequence Elements Required for Endonucleolytic Cleavage of Human Insulin-Like Growth Factor II mRNAs

1995 • 55 citations

A novel transforming growth factor-β₁responsive cytoplasmic frans-acting factor binds selectively to the 3′-untranslated region of mammalian ribonucleotide reductase R2 mRNA: role in message stability

1993 • 51 citations

Autogenous regulation of histone mRNA decay by histone proteins in a cell-free system.

1987 • 45 citations

An RNasin-resistant ribonuclease selective for interleukin 2 mRNA

1993 • 20 citations

Stabilization of Interleukin-2 Receptor-α Chain mRNA by HTLV-1 Rex in Mouse L Cells: Lower Amounts of Rex Do Not Stabilize the mRNA

1994 • 6 citations