Insertion Sequences

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1998 • 7,572 citations

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

1997 • 3,613 citations

The complete genome sequence of the gastric pathogen Helicobacter pylori

1997 • 3,529 citations

Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution

1997 • 1,123 citations

Molecular basis of symbiosis between Rhizobium and legumes

1997 • 767 citations

Conserved sequence motifs in the initiator proteins for rolling circle DNA replication encoded by diverse replicons from eubacteria, eucaryotes and archaebacteria

1992 • 580 citations

Pathogenicity Islands: Bacterial Evolution in Quantum Leaps

1996 • 566 citations

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases.

1992 • 555 citations

Recent Evidence for Evolution of the Genetic Code

1991 • 529 citations

THE RETROVIRAL ENZYMES

1994 • 517 citations

The integrase family of site-specific recombinases: regional similarities and global diversity.

1986 • 515 citations

A purified mariner transposase is sufficient to mediate transposition in vitro.

1996 • 452 citations

Type I repressors of P element mobility.

1993 • 421 citations

TRANSPOSITIONAL RECOMBINATION: Mechanistic Insights from Studies of Mu and Other Elements

1992 • 393 citations

Transposition of R factor genes to bacteriophage lambda.

1975 • 389 citations

The mariner transposable element is widespread in insects

1993 • 386 citations

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

1992 • 376 citations

Tn5 in Vitro Transposition

1998 • 373 citations

IS10 transposition is regulated by DNA adenine methylation

1985 • 341 citations

RECODING: Dynamic Reprogramming of Translation

1996 • 335 citations

Recent evidence for evolution of the genetic code

1992 • 319 citations

Nucleotide sequence of an insertion element, IS1.

1978 • 319 citations

Programmed translational frameshifting

1996 • 316 citations

A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif.

1994 • 312 citations

TARGET SITE SELECTION IN TRANSPOSITION

1997 • 290 citations

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

1991 • 289 citations

Molecular structure of a somatically unstable transposable element in Drosophila.

1986 • 285 citations

Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

1981 • 284 citations

Similarities Between Initiation of V(D)J Recombination and Retroviral Integration

1996 • 280 citations

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

1992 • 276 citations

Disassembly of the Mu transposase tetramer by the ClpX chaperone.

1995 • 276 citations

Insertion of DNA activates the cryptic bgl operon in E. coli K12

1981 • 257 citations

Evidence for a transposon in caenorhabditis elegans

1983 • 257 citations

Residues Critical for Retroviral Integrative Recombination in a Region That Is Highly Conserved among Retroviral/Retrotransposon Integrases and Bacterial Insertion Sequence Transposases

1992 • 244 citations

Tn552, a novel transposable element from Staphylococcus aureus

1990 • 232 citations

IS1 is involved in deletion formation in the gal region of E. coli K12

1975 • 229 citations

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

1997 • 229 citations

Structure of the bacteriophage Mu transposase core: A common structural motif for DNA transposition and retroviral integration

1995 • 225 citations

Integration of the yeast retrotransposon Ty1 is targeted to regions upstream of genes transcribed by RNA polymerase III.

1996 • 221 citations

Translational frameshifting in the control of transposition in bacteria

1993 • 221 citations

Retroviral integrases and their cousins

1996 • 213 citations

Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element.

1996 • 211 citations

Transposon Tn5090 of plasmid R751, which carries an integron, is related to Tn7, Mu, and the retroelements

1994 • 211 citations

Polar mutations in lac, gal and phage λ consist of a few IS-DNA sequences inserted with either orientation

1972 • 210 citations

Transposition and site-specific recombination: adapting DNA cut-and-paste mechanisms to a variety of genetic rearrangements

2006 • 209 citations

Bacterial transposases and retroviral integrases

1995 • 207 citations

Recent horizontal transfer of a mariner transposable element among and between Diptera and Neuroptera.

1995 • 207 citations

Site-specific recognition of the bacteriophage mu ends by the mu a protein

1984 • 207 citations

Origins of the mobile gene cassettes found in integrons

1997 • 206 citations

Functional similarities between retroviruses and the IS3 family of bacterial insertion sequences?

1990 • 205 citations

DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes.

1994 • 204 citations

Unity in Transposition Reactions

1995 • 202 citations

The mechanism of transposition of Tc3 in C. elegans

1994 • 191 citations

Tn7 transposition: Target DNA recognition is mediated by multiple Tn7-encoded proteins in a purified in vitro system

1993 • 189 citations

Evidence for a second conserved arginine residue in the integrase family of recombination proteins

1992 • 185 citations

The enterotoxin gene (cpe) of Clostridium perfringens can be chromosomal or plasmid‐borne

1995 • 185 citations

Computer-assisted dissection of rolling circle DNA replication

1993 • 180 citations

The E. coli gene encoding heat stable toxin is a bacterial transposon flanked by inverted repeats of IS1

1979 • 178 citations

CONJUGATIVE TRANSPOSITION

1995 • 167 citations

Nucleotide sequence of the transposable DNA-element IS2

1979 • 164 citations

IS901, a new member of a widespread class of atypical insertion sequences, is associated with pathogenicity in Mycobacterium avium

1991 • 162 citations

Identification of functional domains and evolution of Tc1-like transposable elements.

1996 • 159 citations

DNA sequence at the integration sites of the insertion element IS1

1978 • 158 citations

The IS4 family of insertion sequences: evidence for a conserved transposase motif

1993 • 156 citations

Polynucleotidyl transfer reactions in transpositional DNA recombination.

1992 • 154 citations

Transposition of Phage Mu DNA

1996 • 150 citations

Distribution and Abundance of Insertion Sequences Among Natural Isolates of Escherichia coli

1987 • 150 citations

IS1 insertion generates duplication of a nine base pair sequence at its target site

1978 • 150 citations

P Elements in Drosophila

1996 • 149 citations

Insertion of a novel DNA sequence, IS 1186, upstream of the silent carbapenemase gene cfiA, promotes expression of carbapenem resistance in clinical isolates of Bacteroides fragilis

1994 • 148 citations

Insertion sequence-related genetic variation in resting Escherichia coli K-12.

1994 • 146 citations

Two kinds of insertions in bacterial genes

1972 • 143 citations

Cell-free V(D)J recombination

1997 • 143 citations

P element transposition in vitro proceeds by a cut-and-paste mechanism and uses GTP as a cofactor

1992 • 142 citations

Target immunity of Mu transposition reflects a differential distribution of Mu B protein

1988 • 141 citations

Tn10 transposase acts preferentially on nearby transposon ends in vivo

1983 • 138 citations

Tn10 transposition and circle formation in vitro

1987 • 138 citations

The ami locus of the Gram‐positive bacterium Streptococcus pneumoniae is similar to binding protein‐dependent transport operons of Gram‐negative bacteria

1990 • 138 citations

Integrons found in different locations have identical 5' ends but variable 3' ends

1994 • 137 citations

Drosophila P element transposase recognizes internal P element DNA sequences

1989 • 136 citations

Translational Control in Production of Transposase and in Transposition of Insertion Sequence IS3

1994 • 134 citations

IS5: a mobile enhancer of transcription in Escherichia coli.

1992 • 133 citations

Chlorobenzoate catabolic transposon Tn5271 is a composite class I element with flanking class II insertion sequences.

1991 • 132 citations

Widespread occurrence of the Tc1 transposon family: Tc1-like transposons from teleost fish

1994 • 132 citations

cis-acting DNA sequence requirements for P-element transposition.

1989 • 132 citations

Programmed translational frameshifting and initiation at an AUU codon in gene expression of bacterial insertion sequence IS911

1991 • 132 citations

A new component of bacteriophage Mu replicative transposition machinery: the Escherichia coli ClpX protein

1994 • 132 citations

Frameshifting is required for production of the transposase encoded by insertion sequence 1.

1989 • 130 citations

ClpX and MuB interact with overlapping regions of Mu transposase: implications for control of the transposition pathway.

1997 • 129 citations

Switching from Cut-and-Paste to Replicative Tn7 Transposition

1996 • 128 citations

ClpX protein of Escherichia coli activates bacteriophage Mu transposase in the strand transfer complex for initiation of Mu DNA synthesis.

1996 • 126 citations

IS200: A salmonella-specific insertion sequence

1983 • 126 citations

The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc

1997 • 124 citations

Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903.

1980 • 123 citations

Drosophila P-element transposase is a novel site-specific endonuclease

1997 • 122 citations

Genetic structure, function and regulation of the transposable element IS21

1989 • 120 citations

The pigmentation locus of Yersinia pestis KIM6+ is flanked by an insertion sequence and includes the structural genes for pesticin sensitivity and HMWP2

1994 • 120 citations

The Mutator Transposable Element System of Maize

1996 • 119 citations

Enhancement of bacterial gene expression by insertion elements or by mutation in a CAP-cAMP binding site

1986 • 116 citations

Effect of dam methylation on Tn5 transposition

1988 • 116 citations

Transposon Tn10 provides a promoter for transcription of adjacent sequences.

1982 • 114 citations

THE TN5 TRANSPOSON

1993 • 113 citations

DNA sequence of the transposable element IS1

1979 • 113 citations

The Tc1/mariner Transposon Family

1996 • 113 citations

Tn10 and IS10 Transposition and Chromosome Rearrangements: Mechanism and Regulation In Vivo and In Vitro

1996 • 111 citations

DNA fingerprinting of Vibrio cholerae strains with a novel insertion sequence element: a tool to identify epidemic strains

1996 • 109 citations

The Three Chemical Steps of Tn10/IS10 Transposition Involve Repeated Utilization of a Single Active Site

1996 • 106 citations

The Clostridium perfringens enterotoxin gene is on a transposable element in type A human food poisoning strains

1997 • 105 citations

DNA sequences at the ends of transposon Tn5 required for transposition

1983 • 103 citations

Rhs elements of Escherichia coli: a family of genetic composites each encoding a large mosaic protein

1994 • 102 citations

Conjugating plasmids are preferred targets for Tn7.

1996 • 101 citations

Identification and characterization of a pre-cleavage synaptic complex that is an early intermediate in Tn10 transposition.

1995 • 101 citations

Repair and Recombination: How to make ends meet

1995 • 101 citations

Differential roles of the transposon termini in IS91transposition.

1994 • 100 citations

IS231 and otherBacillus thuringiensis transposable elements: A review

1994 • 99 citations

Interaction of proteins located at a distance along DNA: Mechanism of target immunity in the Mu DNA strand-transfer reaction

1989 • 99 citations

Sequence analysis of Tn9 insertions in the lacZ gene

1980 • 97 citations

Tc1 transposase of Caenorhabditis elegans is an endonuclease with a bipartite DNA binding domain.

1994 • 95 citations

Catabolic transposons

1994 • 95 citations

Analysis of the Structure and Function of the Kanamycin-resistance Transposon Tn903

1981 • 94 citations

Sequence similarity of putative transposases links the maizeMutatorautonomous element and a group of bacterial insertion sequences

1994 • 94 citations

Mutational analysis of IS10′s outside end.

1989 • 94 citations

Transposase-induced excision and circularization of the bacterial insertion sequence IS911.

1992 • 93 citations

Selected translocation of plasmid genes: frequency and regional specificity of translocation of the Tn3 element

1977 • 93 citations

The evolution of insertion sequences within enteric bacteria.

1992 • 93 citations

Identification of transposable elements which activate gene expression in Pseudomonas cepacia

1987 • 92 citations

Genetic rearrangements in the rfb regions of Vibrio cholerae O1 and O139.

1995 • 92 citations

Characterization of the Caenorhabditis elegans Tc1 transposase in vivo and in vitro.

1993 • 91 citations

High-level ribosomal frameshifting directs the synthesis of IS150gene products

1991 • 91 citations

Multiple copies of iso-insertion sequences of IS1 in Shigella dysenteriae chromosome

1981 • 91 citations

Genetic analysis of the interaction of the insertion sequence IS903 transposase with its terminal inverted repeats.

1987 • 90 citations

Tn10/IS10 transposase purification, activation, and in vitro reaction.

1994 • 90 citations

Transposon Tn7

1989 • 90 citations

Identification, genetic analysis and DNA sequence of a 7.8‐kb virulence region of the Salmonella typhimurium virulence plasmid

1992 • 89 citations

Expression of the strA-strB streptomycin resistance genes in Pseudomonas syringae and Xanthomonas campestris and characterization of IS6100 in X. campestris

1995 • 86 citations

Rearrangements of Genetic Material in Escherichia coli As Observed on the Bacteriophage P1 Plasmid

1979 • 86 citations

Site-specific recombination by Tn3 resolvase

1989 • 85 citations

IS1-mediated intramolecular rearrangements: formation of excised transposon circles and replicative deletions.

1995 • 85 citations

Current ReviewEvolution of Agrobacteria and Their Ti Plasmids - A Review

1992 • 85 citations

Tn10 insertion specificity is strongly dependent upon sequences immediately adjacent to the target-site consensus sequence.

1992 • 84 citations

Distribution of insertion sequence IS200 in Salmonella and Shigella

1990 • 84 citations

DNA transposition: Assembly of a jumping gene machine

1996 • 83 citations

Molecular Epidemiology of Tuberculosis

2014 • 83 citations

Developmental precise excision of Oxytricha trifallax telomere-bearing elements and formation of circles closed by a copy of the flanking target duplication.

1993 • 83 citations

Nucleotide sequence of the prokaryotic mobile genetic element IS30.

1984 • 83 citations

Genotypes and phylogenetic relationships of Salmonella typhimurium are defined by molecular fingerprinting of IS200 and 16S rrn loci

1993 • 83 citations

Novel insertion sequence IS1380 from Acetobacter pasteurianus is involved in loss of ethanol-oxidizing ability

1991 • 82 citations

Nucleotide sequence of the afimbrial-adhesin-encoding afa-3 gene cluster and its translocation via flanking IS1 insertion sequences

1994 • 82 citations

Characterization of the Maize Mutator Transposable Element MURA Transposase as a DNA-Binding Protein

1997 • 82 citations

Functional promoters created by the insertion of transposable element IS1

1986 • 82 citations

IS3 can function as a mobile promoter inE. coli

1982 • 81 citations

An in vivo transposase-catalyzed single-stranded DNA circularization reaction.

1995 • 81 citations

Structure and stability of Tn9-mediated cointegrates

1982 • 81 citations

Nucleotide sequence and structural organization of an insertion sequence element (IS231) from Bacillus thuringiensis strain berliner 1715.

1985 • 81 citations

Target site choice of the related transposable elements Tc1 and Tc3 ofCaenorhabditis elegans

1994 • 80 citations

Translational control of transposition activity of the bacterial insertion sequence IS1.

1991 • 79 citations

Target Site Selection in Transposition of Phage Mu

1993 • 78 citations

Characterization and properties of very large inversions of the E. coli chromosome along the origin-to-terminus axis

1985 • 76 citations

DNA transposition: From a black box to a color monitor

1995 • 75 citations

Recombination between chromosomal IS200 elements supports frequent duplication formation in Salmonella typhimurium.

1995 • 75 citations

IS231A insertion specificity: consensus sequence and DNA bending at the target site

1994 • 75 citations

R68.45, a plasmid with chromosome mobilizing ability (Cma) carries a tandem duplication

1980 • 75 citations

Assembly of a strong promoter following IS911 circularization and the role of circles in transposition

1997 • 75 citations

A specific class of IS10 transposase mutants are blocked for target site interactions and promote formation of an excised transposon fragment

1989 • 74 citations

Transposase promotes double strand breaks and single strand joints at Tn10 termini in vivo

1984 • 73 citations

Insertion Sequence Duplication in Transpositional Recombination

1983 • 73 citations

A role for the KP leucine zipper in regulating P element transposition in Drosophila melanogaster.

1995 • 73 citations

IS10 transposase mutations that specifically alter target site recognition.

1992 • 71 citations

Insertion element IS 1296 in Mycoplasma mycoides subsp. mycoides small colony identifies a European clonal line distinct from African and Australian strains

1995 • 71 citations

Formation of the tandem repeat (IS30)2 and its role in IS30-mediated transpositional DNA rearrangements

1993 • 70 citations

Unusual alleles of recB and recC stimulate excision of inverted repeat transposons Tn10 and Tn5.

1984 • 70 citations

Role of instability in the cis action of the insertion sequence IS903 transposase.

1990 • 70 citations

DNA gyrase is a host factor required for transposition of Tn5

1982 • 69 citations

The Maize Transposable Element Activator (Ac)

1996 • 69 citations

Rhs elements of Escherichia coli K-12: complex composites of shared and unique components that have different evolutionary histories

1993 • 68 citations

Transcriptional and translational initiation sites of IS50

1986 • 68 citations

Maize Activator transposase has a bipartite DNA binding domain that recognizes subterminal sequences and the terminal inverted repeats

1997 • 68 citations

Mutagenesis of the Paracrystalline Surface Protein Array of Aeromonas salmonicida by Endogenous Insertion Elements

1994 • 68 citations

Structural requirement for IS50-mediated gene transposition.

1983 • 68 citations

IS150: distribution, nucleotide sequence and phylogenetic relationships of a newE.coliinsertion element

1988 • 68 citations

Replicon fusions promoted by the inverted repeats of Tn5

1981 • 68 citations

Characterization and distribution of two insertion sequences, IS1191 and iso‐IS981, in Streptococcus thermophilus: does intergeneric transfer of insertion sequences occur in lactic acid bacteria co‐cultures?

1995 • 68 citations

Tn10 protects itself at two levels from fortuitous activation by external promoters

1985 • 67 citations

The Drosophila P-Element KP Repressor Protein Dimerizes and Interacts with Multiple Sites on P-Element DNA

1996 • 67 citations

Factors determining frequency of plasmid cointegration mediated by insertion sequence IS 1

1982 • 67 citations

Two abundant intramolecular transposition products, resulting from reactions initiated at a single end, suggest that IS2 transposes by an unconventional pathway

1997 • 67 citations

Does the insertion element IS1 transpose preferentially into A+T-rich DNA segments?

1980 • 66 citations

Nucleotide sequence of IS492, a novel insertion sequence causing variation in extracellular polysaccharide production in the marine bacterium Pseudomonas atlantica

1989 • 66 citations

Transposable elements: How non-LTR retrotransposons do it

1997 • 65 citations

Expression of proteins essential for IS1 transposition: specific binding of InsA to the ends of IS1.

1987 • 64 citations

Mutational analysis of insertion sequence 50 (IS50) and transposon 5 (Tn5) ends.

1988 • 63 citations

IS30, a new insertion sequence of Escherichia coli K12

1984 • 63 citations

Fis plays a role in Tn5 and IS50 transposition

1992 • 63 citations

Detection and Characterization of IS256, an Insertion Sequence in Staphylococcus aureus

1987 • 63 citations

Efficient transposition of IS911 circles invitro

1998 • 63 citations

IS91 transposase is related to the rolling-circle-type replication proteins of the pUB110 family of plasmids

1992 • 62 citations

Adaptation of Xanthobacter autotrophicus GJ10 to bromoacetate due to activation and mobilization of the haloacetate dehalogenase gene by insertion element IS1247

1995 • 61 citations

Bacteriophage Mu repressor as a target for the Escherichia coli ATP-dependent Clp Protease.

1996 • 60 citations

Specificity of insertion of IS1

1985 • 60 citations

Binding of the IS903 transposase to its inverted repeat in vitro.

1992 • 60 citations

IS911-mediated Transpositional Recombinationin Vitro

1996 • 59 citations

The mechanism of sequence-specific DNA cleavage and strand transfer by phi X174 gene A* protein.

1993 • 59 citations

Gamma delta transposase and integration host factor bind cooperatively at both ends of gamma delta.

1988 • 58 citations

Bacterial Interspersed Mosaic Elements (BIMEs) Are a Major Source of Sequence Polymorphism in Escherichia coli Intergenic Regions Including Specific Associations With a New Insertion Sequence

1997 • 58 citations

Multiple group II self-splicing introns in mobile DNA from Escherichia coli.

1994 • 58 citations

Characterization of the Tn5 transposase and inhibitor proteins: a model for the inhibition of transposition

1993 • 57 citations

Characterization of IS 1110, a highly mobiie genetic element from Mycobacterium avium

1994 • 57 citations

Isolation of the closed circular form of the transposable element Tc1 in Caenorhabditis elegans

1984 • 56 citations

DNA binding activities of the Caenorhabditis elegans Tc3 transposase

1994 • 56 citations

Drosophila P-element transposase is a transcriptional repressor in vitro.

1991 • 55 citations

Structures of Homologous Composite Transposons Carrying cbaABC Genes from Europe and North America

1998 • 54 citations

Induction of the SOS Response by IS1 Transposase

1994 • 54 citations

Selfish DNAs with self-restraint

1984 • 54 citations

Novel rearrangements of IS30 carrying plasmids leading to the reactivation of gene expression

1987 • 53 citations

Transposon Tn7

1996 • 53 citations

The regulatory role of the IS 1‐encoded InsA protein in transposition

1990 • 53 citations

Subunit Interactions in the mariner Transposase

1996 • 52 citations

Multiple oligomerisation domains in the IS911 transposase: a leucine zipper motif is essential for activity

1998 • 51 citations

Isolation and analysis of IS6120, a new insertion sequence from Mycobacterium smegmatis

1992 • 51 citations

IS10/Tn10 transposition efficiently accommodates diverse transposon end configurations.

1996 • 51 citations

The Transposon‐Like Structure of IS26‐Tetracycllne, and Kanamycin Resistance Determinant Derived from Transferable R Plasmid of Fish Pathogen, Pasteurella piscicida

1994 • 51 citations

dnaA, an essential host gene, and Tn5 transposition

1987 • 49 citations

Isolation and characterization of IS 31831, a transposable element from Corynebacterium glutamicum

1994 • 49 citations

Structural and functional analysis of the mini‐circle, a transposable element of Streptomyces coelicolor A3(2)

1989 • 49 citations

The N-terminal domain of the insertion sequence 30 transposase interacts specifically with the terminal inverted repeats of the element.

1990 • 48 citations

A Functional Analysis of the Tn5 Transposase Identification of Domains Required for DNA Binding and Multimerization

1994 • 48 citations

Mode of Replicon Fusion Mediated by the Duplicated Insertion Sequence IS21 in Escherichia coli

1987 • 47 citations

Nucleotide sequence and characterization of a new insertion element, IS240, from Bacillus thuringiensis israelensis

1989 • 47 citations

Steady-state kinetic analysis of ATP hydrolysis by the B protein of bacteriophage mu. Involvement of protein oligomerization in the ATPase cycle.

1991 • 47 citations

Insertion element IS1 encodes two structural genes required for its transposition

1984 • 47 citations

A covalent complex between retroviral integrase and nicked substrate DNA.

1991 • 46 citations

Escherichia coli alpha-haemolysin synthesis and export genes are flanked by a direct repetition of IS91-like elements

1984 • 46 citations

A complex array of Hpr consensus DNA recognition sequences proximal to the enterotoxin gene in Clostridium perfringens type A

1994 • 46 citations

Nucleotide sequence of the transposable element IS15

1984 • 45 citations

Alternate Strand DNA Triple Helix-mediated Inhibition of HIV-1 U5 Long Terminal Repeat Integration in Vitro

1996 • 45 citations

The ancestry of insertion sequences common to Escherichia coli and Salmonella typhimurium

1993 • 43 citations

The Mu strong gyrase‐binding site promotes efficient synapsis of the prophage termini

1996 • 43 citations

Negative and positive regulation of Tn10/IS10-promoted recombination by IHF: two distinguishable processes inhibit transposition off of multicopy plasmid replicons and activate chromosomal events that favor evolution of new transposons.

1995 • 43 citations

Gene organization and target specificity of the prokaryotic mobile genetic element IS26

1985 • 43 citations

Nucleotide sequence and structural organization ofYersinia pestisinsertion sequence IS100

1994 • 43 citations

The En/Spm Transposable Element of Maize

1996 • 42 citations

Regulation of IS1 transposition by the insA gene product

1989 • 42 citations

Identification and characterization of IS 1138, a transposable element from Mycoplasma pulmonis that belongs to the IS3 family

1993 • 42 citations

The flagellin N-methylase gene fliB and an adjacent serovar-specific IS200 element in Salmonella typhimurium

1997 • 42 citations

Mobilization of quiet, endogenous Tc3 transposons of Caenorhabditis elegans by forced expression of Tc3 transposase.

1993 • 42 citations

Insertion sequence IS6100 on plasmid pOAD2, which degrades nylon oligomers

1994 • 42 citations

The transposable element En/Spm-encoded TNPA protein contains a DNA binding and a dimerization domain

1993 • 41 citations

‘Muprints’ of the lac operon demonstrate physiological control over the randomness of in vivo transposition

1994 • 41 citations

Possible role of insertion sequence IS257 in dissemination and expression of high- and low-level trimethoprim resistance in staphylococci

1994 • 41 citations

Factors affecting transposition activity of IS50 and Tn5 ends

1989 • 41 citations

Discovery and characterization of a new transposable element, Tn4811, in Streptomyces lividans 66

1992 • 40 citations

Transcriptional occlusion of transposon targets

1989 • 39 citations

Amino acid sequence homology between Piv, an essential protein in site-specific DNA inversion in Moraxella lacunata, and transposases of an unusual family of insertion elements

1994 • 39 citations

A new class of mutants in DNA polymerase I that affects gene transposition

1982 • 39 citations

Mutations that affect Tn5 insertion into pBR322: importance of local DNA supercoiling

1990 • 39 citations

Molecular characterization of catalase from Bordetella pertussis: identification of the katA promoter in an upstream insertion sequence

1994 • 38 citations

IS200is not a member of the IS600family of insertion sequences

1991 • 38 citations

Functional organization of the ends of IS1: specific binding site for an IS 1-encoded protein.

1990 • 38 citations

Conserved structure of IS200 elements in Salmonella

1997 • 38 citations

Characterization of an IS-like element from Mycobacterium tuberculosis

1993 • 38 citations

ISH51: a large, degenerate family of insertion sequence-like elements in the genome of the archaehacterium,Halobacterium volcanii

1986 • 37 citations

Characterization of IS1167, a New Insertion Sequence in Streptococcus pneumoniae

1995 • 37 citations

Four types of IS1 with differences in nucleotide sequence reside in the Escherichia coli K-12 chromosome

1991 • 36 citations

DNA sequence of IS91 and identification of the transposase gene

1992 • 36 citations

The requirement for both DNA polymerase and 5′ to 3′ exonuclease activities of DNA polymerase I during Tn5 transposition

1981 • 36 citations

A fusion promoter created by a new insertion sequence, IS1490, activates transcription of 2,4,5-trichlorophenoxyacetic acid catabolic genes in Burkholderia cepacia AC1100

1997 • 36 citations

Identification of a native Dichelobacter nodosus plasmid and implications for the evolution of the vap regions

1996 • 36 citations

Evidence for a group II intron inEscherichia coliinserted into a highly conserved reading frame associated with mobile DNA sequences

1994 • 35 citations

Cis preference of the IS 903 transposase is mediated by a combination of transposase instability and inefficient translation

1996 • 35 citations

Identification of citrate utilization transposon Tn3411 from a naturally occurring citrate utilization plasmid

1982 • 34 citations

Specificity of insertion of IS91, an insertion sequence present in α‐haemolysin plasmids of Escherichia coli

1989 • 34 citations

Isolation, characterization and transposition of an (IS2)2 intermediate

1996 • 34 citations

Iron Transport Genes of the pJM1-Mediated Iron Uptake System of Vibrio anguillarum Are Included in a Transposonlike Structure

1995 • 34 citations

Preferential cis action of IS 10 transposase depends upon its mode of synthesis

1993 • 34 citations

Role of ner protein in bacteriophage Mu transposition

1986 • 34 citations

IS911‐mediated intramolecular transposition is naturally temperature sensitive

1997 • 34 citations

p43, the protein product of the atypical insertion sequence IS900, is expressed in Mycobacterium paratuberculosis

1992 • 34 citations

The two single-strand cleavages at each end of Tn10 occur in a specific order during transposition.

1995 • 33 citations

Transcriptional activation of the citrate permease P gene ofLactococcus lactis biovardiacetylactis by an insertion sequence-like element present in plasmid pCIT264

1996 • 32 citations

Characterization of a mosaic ISS1 element and evidence for the recent horizontal transfer of two different types of ISS1 between Streptococcus thermophilus and Lactococcus lactis

1996 • 32 citations

Transposition and transposition immunity of transposon Tn3 derivatives having different ends.

1984 • 32 citations

The istA gene of insertion sequence IS21 is essential for cleavage at the inner 3′ ends of tandemly repeated IS21 elements in vitro.

1990 • 32 citations

Characterization of the transposon carrying the STII gene of enterotoxigenic Escherichia coli

1988 • 32 citations

Characterization of IS1221 from Mycoplasma hyorhinis: expression of its putative transposase in Escherichia coli incorporates a ribosomal frameshift mechanism

1995 • 32 citations

Site-specific transposition of insertion sequence IS630

1990 • 31 citations

An Antisense RNA in IS30 Regulates the Translational Expression of the Transposase

1997 • 31 citations

IS1500, an IS3-like element from Leptospira interrogans

1995 • 31 citations

IS103, a new insertion element in Escherichia coli: characterization and distribution in natural populations.

1989 • 31 citations

One-ended insertion of IS911

1994 • 31 citations

DNA sequence at the end of IS1 required for transposition

1985 • 30 citations

Substrate specificity of Ty1 integrase

1995 • 30 citations

Promotion of RNA transcription on the insertion element IS30 of E. coli K12.

1985 • 30 citations

Mobilization of Chromosomes and Nonconjugative Plasmids by Cointegrative Mechanisms

1993 • 30 citations

Terminal inverted repeats of prokaryotic transposable element IS186 which can generate duplications of variable length at an identical target sequence

1986 • 30 citations

Excision and transposition of Tn5 as an SOS activity in Escherichia coli.

1991 • 30 citations

Transposable element IS1 intrinsically generates target duplications of variable length.

1985 • 29 citations

The Salmonella wien virulence plasmid pZM3 carries Tn1935, a multiresistance transposon containing a composite IS1936-kanamycin resistance element

1988 • 29 citations

Communication of ClpXP protease hypersensitivity to bacteriophage mu repressor isoforms

1997 • 29 citations

Identification and characterization of IS-like elements in Mycobacterium gordonae

2006 • 29 citations

A cloned DNA fragment from bacteriophage P1 enhances IS2 insertion

1987 • 29 citations

Characterization and sequence of a novel insertion sequence, IS162, from pseudomonas fluorescens

1995 • 28 citations

Two domains in the terminal inverted-repeat sequence of transposon Tn3

1990 • 28 citations

Mutational analysis of the open reading frames in the transposable element IS1.

1988 • 28 citations

MECHANISM OF IS1 TRANSPOSITION IN E. COLI: CHOICE BETWEEN SIMPLE INSERTION AND COINTEGRATION

1984 • 27 citations

Retroviral DNA integration: lessons for transposon shuffling

1993 • 27 citations

Interaction of Tn5 Transposase with the Transposon Termini

1994 • 26 citations

Factors determining the frequency of plasmid cointegrate formation mediated by insertion sequence IS3 from Escherichia coli

1991 • 26 citations

Preferential transposition of an IS630-associated composite transposon to TA in the 5'-CTAG-3' sequence

1991 • 26 citations

A transposon-like element on the lactose plasmid of Lactococcus lactis subsp. lactis Z270

1991 • 26 citations

Reprogramming the purine nucleotide cofactor requirement of Drosophila P element transposase invivo

1997 • 25 citations

GENETIC MAPPING OF IS200 COPIES IN SALMONELLA TYPHIMURIM STRAIN LT2

1983 • 25 citations

Escherichia coli RNA polymerase binding sites and transcription initiation sites in the transposon Tn3

1983 • 24 citations

Characterization of the IS895 family of insertion sequences from the cyanobacterium Anabaena sp. strain PCC 7120

1991 • 24 citations

Functional organization of the ends of IS 1: specific binding site for an IS1‐encoded protein

1990 • 24 citations

Insertional inactivation of an Escherichia coli urease gene by IS3411

1992 • 24 citations

Functional Analysis of the 14 kDa Protein of Insertion Sequence 2

1994 • 23 citations

Plasmid reference center registry of transposon (Tn) allocations through July 1981

1981 • 23 citations

Molecular analysis of an IS200 insertion in the gpt gene of Salmonella typhimurium LT2

1990 • 23 citations

Inducible transposition in Streptomyces lividans of insertion sequence IS6100 from Mycobacterium fortuitum

1995 • 22 citations

Integration host factor increases the transpositional immunity conferred by gamma delta ends

1990 • 22 citations

Tn3 transposition immunity is conferred by the transposase-binding domain in the terminal inverted-repeat sequence of Tn3

1990 • 22 citations

Evidence for a role of translational frameshifting in the expression of transposition activity of the bacterial insertion element IS1

1990 • 22 citations

Artificial transposable elements in the study of the ends of IS1

1987 • 22 citations

Identification and Characterization of the Linear IS3 Molecules Generated by Staggered Breaks

1996 • 22 citations

Transposition of Tn5096 and related transposons in Streptomyces species

1992 • 22 citations

IS870 requires a 5'-CTAG-3' target sequence to generate the stop codon for its large ORF1

1993 • 21 citations

Mutagenesis of the IS1 transposase: importance of a His-Arg-Tyr triad for activity

1995 • 21 citations

Isolation and characterization of IS1 circles

1997 • 21 citations

DNA binding domains in Tn3 transposase

1993 • 20 citations

Induction of the SOS response in Escherichia coli inhibits Tn5 and IS50 transposition

1991 • 20 citations

Cointegrate formation by IS50 requires multiple donor molecules

1988 • 20 citations

LexA protein of Escherichia coli represses expression of the Tn5 transposase gene

1991 • 20 citations

A transposon-like element on the lactose plasmid ofLactococcus lactissubsp.lactisZ270

1991 • 19 citations

Structural domains of IS10 transposase and reconstitution of transposition activity from proteolytic fragments lacking an interdomain linker.

1995 • 19 citations

Base substitutions in transposable element IS1 cause DNA duplication of variable length at the target site for plasmid co-integration.

1987 • 19 citations

Transposition of IS117 (the Streptomyces coelicolor A3(2) mini-circle) to and from a cloned target site and into secondary chromosomal sites

1990 • 19 citations

Transposons and Their Applications

2014 • 19 citations

Nucleotide sequence analysis of IS427 and its target sites inAgrobacterium tumefaciens T37

1990 • 19 citations

Further evidence that transposition of Tn5 in Escherichia coli is strongly enhanced by constitutively activated RecA proteins

1992 • 18 citations

Spontaneous deletion of citrate-utilizing ability promoted by insertion sequences

1984 • 18 citations

Inversion in the lactose region of Escherichia coli K-12: inversion termini map within IS3 elements alpha 3 beta 3 and beta 5 alpha 5

1983 • 18 citations

Hybrid dysgenesis inDrosophila melanogaster: partial sterility associated with embryo lethality in theP-Msystem

1984 • 18 citations

Catalytic center quest: comparison of transposases belonging to the Tn3 family reveals an invariant triad of acidic amino acid residues.

1996 • 18 citations

Reshuffling of Rhs components to create a new element

1995 • 17 citations

Defining functional regions of the IS903 transposase

1997 • 16 citations

Interruption of the Streptococcus gordonii M5 sspA/sspB intergenic region by an insertion sequence related to IS1167 of Streptococcus pneumoniae

1997 • 16 citations

Evidence for replicative transposition of Tn5 and Tn9

1986 • 15 citations

Extrachromosomal circular copies of the transposon Tc1

1993 • 15 citations

Insertions of transposable elements in the promoter proximal region of the gene cluster for Escherichia coli H+-ATPase: 8 base pair repeat generated by insertion of IS1

1984 • 15 citations

A transcriptional terminator sequence in the prokaryotic transposable element IS1

1987 • 14 citations

Specific nicking at the 3′ ends of the terminal inverted repeat sequences in transposon Tn3 by transposase and an E. coli protein ACP

1996 • 14 citations

Uncoupling of transpositional immunity from gamma delta transposition by a mutation at the end of gamma delta

1990 • 13 citations

Is the IS1 transposase, InsAB', the only IS1-encoded protein required for efficient transposition?

1994 • 12 citations

Functional domains of the InsA protein of IS2

1997 • 12 citations

Characterization of transposon Tn5469 from the cyanobacterium Fremyella diplosiphon

1995 • 11 citations

Genetic Evidence for IS1 Transposition Regulated by InsA and the ΔInsA-B′-InsB Species, which is Generated by Translation from Two Alternative Internal Initiation Sites and Frameshifting

1994 • 11 citations

Restriction fragment length polymorphism analysis ofFusobacterium necrophorumusing a novel repeat DNA sequence and a 16S rRNA gene probe

1993 • 10 citations

IS231A transposition: conservative versus replicative pathway

1998 • 9 citations

Tn602: A naturally occurring relative of Tn903 with direct repeats

1987 • 9 citations

Genetic analyses of the interactions of the IS 1 -encoded proteins with the left end of IS 1 and its insertion hotspot 1 1Edited by J. Karn

1997 • 8 citations

Mutations in the inverted repeats of Tn3 affect binding of transposase and transposition immunity

1991 • 8 citations

Isolation and Characterization of the IS3-like Element fromThermus aquaticus

1995 • 7 citations

[Immunity to repeated transposition of the insertion sequence IS21].

1985 • 6 citations

Transcription of the target is required for IS102 mediated deletions

1988 • 6 citations

[The role of IS-elements of Yersinia pestis (Lehmann, Neumann) in the emergence of calcium-independent mutations].

1990 • 5 citations

[22] Tn5 lacZ Translation fusion element: Isolation and analysis of transposition mutants

1993 • 3 citations

Role of replication in IS 102-mediated deletion formation

1987 • 3 citations