Retroviral integrase domains: DNA binding and the recognition of LTR sequences

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

Analysis of gene control signals by DNA fusion and cloning in Escherichia coli

1980 • 2,499 citations

DNA TOPOISOMERASES

1985 • 1,524 citations

Origins and Evolutionary Relationships of Retroviruses

1989 • 581 citations

Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions

1990 • 485 citations

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.

1986 • 483 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1990 • 411 citations

Proposed structure for the zinc-binding domains from transcription factor IIIA and related proteins.

1988 • 411 citations

[39] Unified approach to alignment and phylogenies

1990 • 398 citations

Retroviral DNA integration: Structure of an integration intermediate

1988 • 397 citations

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro

1990 • 350 citations

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1989 • 311 citations

Origin of retroviruses from cellular moveable genetic elements

1980 • 300 citations

High-resolution structure of an HIV zinc fingerlike domain via a new NMR-based distance geometry approach

1990 • 268 citations

Highly preferred targets for retrovirus integration

1988 • 262 citations

Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence

1989 • 260 citations

Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection

1984 • 244 citations

Sequence and spacing requirements of a retrovirus integration site

1988 • 215 citations

A mutant murine leukemia virus with a single missense codon in pol is defective in a function affecting integration.

1984 • 182 citations

Phenylalanines that are conserved among several RNA-binding proteins form part of a nucleic acid-binding pocket in the A1 heterogeneous nuclear ribonucleoprotein.

1988 • 180 citations

Versatile expression vectors for high-level synthesis of cloned gene products in Escherichia coli

1985 • 174 citations

Nucleotide sequence analysis of the Long Terminal Repeat (LTR) of avian retroviruses: Structural similarities with transposable elements

1980 • 173 citations

A model for the tertiary structure of the 28 residue DNA-binding motif (‘zinc finger’) common to many eukaryotic transcriptional regulatory proteins

1988 • 159 citations

A retroviral Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys peptide binds metal ions: spectroscopic studies and a proposed three-dimensional structure.

1989 • 153 citations

Mutants and pseudorevertants of moloney murine leukemia virus with alterations at the integration site

1985 • 135 citations

Genetic variability between isolates of human immunodeficiency virus (HIV) type 2 is comparable to the variability among HIV type 1.

1988 • 117 citations

[20] Mutation data matrix and its uses

1990 • 100 citations

PEPPLOT, a protein secondary structure analysis program for the UWGCG sequence analysis software package

1986 • 73 citations

Selective cleavage in the avian retroviral long terminal repeat sequence by the endonuclease associated with the alpha beta form of avian reverse transcriptase.

1983 • 71 citations

Identification of aspartate-184 as an essential residue in the catalytic subunit of cAMP-dependent protein kinase

1988 • 70 citations

Avian sarcoma and leukosis virus pol-endonuclease recognition of the tandem long terminal repeat junction: minimum site required for cleavage is also required for viral growth

1987 • 64 citations

Structural characterization of the avian retrovirus reverse transcriptase and endonuclease domains.

1985 • 60 citations

Requirement of the avian retrovirus pp32 DNA binding protein domain for replication

1984 • 59 citations

Avian Retrovirus pp32 DNA-Binding Protein I. Recognition of Specific Sequences on Retrovirus DNA Terminal Repeats

1982 • 57 citations

Properties of avian sarcoma-leukosis virus pp32-related pol-endonucleases produced in Escherichia coli

1988 • 55 citations

Dicyclohexylcarbodiimide cross-links two conserved residues, Asp-184 and Lys-72, at the active site of the catalytic subunit of cAMP-dependent protein kinase

1989 • 55 citations

Circles with two tandem long terminal repeats are specifically cleaved by pol gene-associated endonuclease from avian sarcoma and leukosis viruses: nucleotide sequences required for site-specific cleavage

1985 • 54 citations

Proteolytic processing of avian sarcoma and leukosis viruses pol-endo recombinant proteins reveals another pol gene domain

1987 • 51 citations

Site-specific nicking at the avian retrovirus LTR circle junction by the viral pp32 DNA endonuclease

1985 • 45 citations

Avian retrovirus pp32 DNA binding protein. Preferential binding to the promoter region of long terminal repeat DNA

1984 • 31 citations

A C-terminal domain in the avian sarcoma-leukosis virus pol gene product is not essential for viral replication

1988 • 28 citations

[58] Procedures for in vitro DNA mutagenesis of human leukocyte interferon sequences

1986 • 27 citations

Avian retrovirus nucleocapsid protein, pp12, produced in Escherichia coli has biochemical properties identical to unphosphorylated viral protein

1986 • 15 citations