P element transposition in vitro proceeds by a cut-and-paste mechanism and uses GTP as a cofactor

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

The Significance of Responses of the Genome to Challenge

1984 • 2,520 citations

Transposition of Cloned P Elements into Drosophila Germ Line Chromosomes

1982 • 1,560 citations

Structures of P transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome

1983 • 794 citations

Analysis of P transposable element functions in drosophila

1984 • 733 citations

Vectors for P element-mediated gene transfer inDrosophila

1983 • 491 citations

The molecular basis of P-M hybrid dysgenesis: The nature of induced mutations

1982 • 484 citations

High-frequency P element loss in Drosophila is homolog dependent

1990 • 446 citations

Retroviral DNA integration: Structure of an integration intermediate

1988 • 397 citations

Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

1989 • 392 citations

Targeted Gene Replacement in Drosophila Via P Element-Induced Gap Repair

1991 • 352 citations

Transpososomes: Stable protein-DNA complexes involved in the in vitro transposition of bacteriophage Mu DNA

1987 • 231 citations

Eukaryotic topoisomerase II. Characterization of enzyme turnover.

1986 • 213 citations

Transposition of Mu DNA: Joining of Mu to target DNA can be uncoupled from cleavage at the ends of Mu

1987 • 172 citations

Inversion of the phosphate chirality at the target site of Mu DNA strand transfer: Evidence for a one-step transesterification mechanism

1991 • 166 citations

Tn7 transposition in vitro proceeds through an excised transposon intermediate generated by staggered breaks in DNA

1991 • 159 citations

MOLECULAR MECHANISMS REGULATING DROSOPHILA P ELEMENT TRANSPOSITION

1990 • 148 citations

Drosophila P element transposase recognizes internal P element DNA sequences

1989 • 136 citations

cis-acting DNA sequence requirements for P-element transposition.

1989 • 132 citations

B protein of bacteriophage mu is an ATPase that preferentially stimulates intermolecular DNA strand transfer.

1987 • 122 citations

A trans -Acting Product Needed for P Factor Transposition in Drosophila

1984 • 122 citations

P1 plasmid replication: initiator sequestration is inadequate to explain control by initiator-binding sites

1988 • 113 citations

Vectors containing a prokaryotic dihydrofolate reductase gene transform Drosophila cells to methotrexate-resistance.

1983 • 109 citations

Identification and purification of a Drosophila protein that binds to the terminal 31-base-pair inverted repeats of the P transposable element.

1988 • 109 citations

Regulation of Drosophila P element transposition

1991 • 105 citations

Intramolecular transposition by Tn10

1989 • 94 citations

Transformation of Cultured Drosophila melanogaster Cells with a Dominant Selectable Marker

1985 • 93 citations

A specific terminal structure is required for Ty1 transposition.

1990 • 76 citations

Kinetic and structural analysis of a cleaved donor intermediate and a strand transfer intermediate in Tn10 transposition

1991 • 75 citations

Transformation of cultured Drosophila melanogaster cells with a dominant selectable marker.

1985 • 69 citations

Mechanism of transposition of bacteriophage mu: polarity of the strand transfer reaction at the initiation of transposition

1984 • 66 citations

Drosophila P-element transposase is a transcriptional repressor in vitro.

1991 • 55 citations

GTP: A Central Regulator of Cellular Anabolism

1985 • 55 citations

Capture of flanking DNA by a P element in Drosophila melanogaster: creation of a transposable element.

1991 • 32 citations

P element transposition

1990 • 24 citations

Germline transformation ofDrosophila melanogasterby purified P element transposase

1991 • 16 citations

In vitro transposition of transposon Tn3.

1990 • 14 citations