DNA gyrase is a host factor required for transposition of Tn5

Experiments in molecular genetics

1972 • 28,260 citations

In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals

1980 • 1,052 citations

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

1977 • 777 citations

TRANSPOSABLE ELEMENTS IN PROKARYOTES

1981 • 765 citations

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase.

1976 • 719 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

Conformational fluctuations of DNA helix.

1975 • 562 citations

Molecular model for the transposition and replication of bacteriophage Mu and other transposable elements.

1979 • 503 citations

Action of nicking-closing enzyme on supercoiled and nonsupercoiled closed circular DNA: formation of a Boltzmann distribution of topological isomers.

1975 • 378 citations

Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth

1979 • 337 citations

Replication of bacteriophage λ DNA dependent on the function of host and viral genes

1973 • 265 citations

INTEGRATION AND EXCISION OF BACTERIOPHAGE λ: THE MECHANISM OF CONSERVATIVE SITE SPECIFIC RECOMBINATION

1981 • 249 citations

Transposon-mediated site-specific recombination: A defined in vitro system

1981 • 227 citations

Cleavage of Circular, Superhelical Simian Virus 40 DNA to a Linear Duplex by S ₁ Nuclease

1973 • 207 citations

Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase

1979 • 197 citations

The inverted repeats of Tn are functionally different

1980 • 191 citations

Nicking-closing activity associated with bacteriophage lambda int gene product.

1979 • 182 citations

DNA supercoiling: Another level for regulating gene expression

1981 • 166 citations

Dominant constitutive mutations in malT, the positive regulator gene of the maltose regulon in Escherichia coli

1978 • 165 citations

Identification of the protein encoded by the transposable element Tn 3 which is required for its transposition

1979 • 148 citations

Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system.

1980 • 145 citations

The functional differences in the inverted repeats of Tn5 are caused by a single base pair nonhomology

1981 • 139 citations

Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase

1978 • 130 citations

Transposition protein of Tn3: identification and characterisation of an essential represser-controlled gene product

1979 • 112 citations

Replication of small plasmids in extracts of Escherichia coli

1976 • 103 citations

A mechanism of DNA transposition.

1981 • 98 citations

Analysis of the Structure and Function of the Kanamycin-resistance Transposon Tn903

1981 • 94 citations

Involvement of supertwisted DNA in integrative recombination of bacteriophage lambda

1978 • 92 citations

Genetic fusions defining trp and lac operon regulatory elements

1975 • 86 citations

Insertion, Excision, and Inversion of Tn5

1981 • 73 citations

Replicon fusions promoted by the inverted repeats of Tn5

1981 • 68 citations

Action of the single-stranded DNA specific nuclease S1 on double-stranded DNA

1973 • 46 citations

Integrative Recombination of Bacteriophage : Requirement for Supertwisted DNA In Vivo and Characterization of Int

1979 • 44 citations

A new class of mutants in DNA polymerase I that affects gene transposition

1982 • 39 citations

The requirement for both DNA polymerase and 5′ to 3′ exonuclease activities of DNA polymerase I during Tn5 transposition

1981 • 36 citations

Integrative Recombination of Bacteriophage : In Vitro Study of the Intermolecular Reaction

1979 • 34 citations

The form of the DNA substrate required for excisive recombination of bacteriophage λ

1979 • 33 citations

Conferral of transposable properties to a chromosomal gene in Escherichia coli

1980 • 20 citations

Isolation of a polA Mutation That Affects Transposition of Insertion Sequences and Transposons

1981 • 17 citations

Isolation and mapping of Escherichia coli K12 mutants defective in Tn9 transposition

1981 • 9 citations