Structural and functional analysis of the mini‐circle, a transposable element of Streptomyces coelicolor A3(2)

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

PROTEIN-DNA RECOGNITION

1984 • 1,649 citations

Recognition of protein coding regions in DNA sequences

1982 • 927 citations

The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences

1984 • 820 citations

TRANSPOSABLE ELEMENTS IN PROKARYOTES

1981 • 765 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Plasmids, Recombination and Chromosome Mapping in Streptomyces lividans 66

1983 • 416 citations

Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator

1986 • 403 citations

pUR222, a vector for cloning and rapid chemical sequencing of DNA

1981 • 267 citations

Regeneration of insertionally inactivated streptococcal DNA fragments after excision of transposon Tn916 in Escherichia coli: strategy for targeting and cloning of genes from gram-positive bacteria

1984 • 267 citations

A transposon in Streptococcus faecalis with fertility properties

1982 • 251 citations

Regulation of Secondary Metabolism in Actinomycetes

2020 • 174 citations

Cloning and characterization of EcoRI and HindIII restriction endonuclease-generated fragments of antibiotic resistance plasmids R6-5 and R6

1978 • 166 citations

Transposon Tn554: complete nucleotide sequence and isolation of transposition-defective and antibiotic-sensitive mutants.

1985 • 152 citations

Unique insertion site of Tn7 in the E. coli chromosome

1982 • 151 citations

Excision of chromosomal DNA sequences from Streptomyces coelicolor forms a novel family of plasmids detectable in Streptomyces lividans

1981 • 142 citations

An intermediate in transposition of the conjugative transposon Tn916.

1988 • 142 citations

Sequence analysis of termini of conjugative transposon Tn916

1988 • 136 citations

Genetic structure, function and regulation of the transposable element IS21

1989 • 120 citations

Transposition of Tn554 does not generate a target duplication

1984 • 90 citations

Isolation and characterization of dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12

1980 • 85 citations

Analysis of Tn7 transposition

1986 • 80 citations

Plasmid formation in Streptomyces: Excision and integration of the SLP1 replicon at a specific chromosomal site

1984 • 57 citations

Transposon Tn554 encodes three products required for transposition.

1988 • 57 citations

Nucleotide sequence ofIS110, an insertion sequence ofStreptomyces coelicolorA3(2)

1987 • 54 citations

Genetic Manipulation

1988 • 54 citations

Structural analysis of loci involved in pSAM2 site-specific integration in Streptomyces

1989 • 51 citations

Genome size ofStreptomyces

1984 • 50 citations

A 2.6 kb DNA sequence of Streptomyces coelicolor A3(2) which functions as a transposable element

1986 • 48 citations

Structural analysis of plasmid and chromosomal loci involved in site-specific excision and integration of the SLP1 element of Streptomyces coelicolor

1986 • 48 citations

Comparative Electrophoretic Polymorphism of Esterases and Other Enzymes in Escherichia coli

1989 • 46 citations

Inhibition of transient gene expression in Chinese hamster ovary cells by cyclobutane dimers and (6-4) photoproducts in transfected ultraviolet-irradiated plasmid DNA

1989 • 46 citations

Recognition of Escherichia coli attTn7 by transposon Tn7: lack of specific sequence requirements at the point of Tn7 insertion

1988 • 43 citations

Site-specific integration and excision of pMEA100 in Nocardia mediterranei

1987 • 41 citations

Tsetse fly rDNA: an analysis of structure and sequence

1987 • 40 citations

Physical and genetic analysis of IS110, a transposable element of Streptomyces coelicolor A3(2)

1985 • 35 citations

Construction in vitro of a cloned nar operon from Escherichia coli

1984 • 30 citations

Transposition of IS91 does not generate a target duplication

1987 • 25 citations

Drug Resistance in Bacteria

1972 • 14 citations