Residues Critical for Retroviral Integrative Recombination in a Region That Is Highly Conserved among Retroviral/Retrotransposon Integrases and Bacterial Insertion Sequence Transposases

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Structural basis for the 3′-5′ exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism.

1991 • 1,059 citations

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

1991 • 640 citations

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

1991 • 566 citations

Computer analysis of retroviral pol genes: assignment of enzymatic functions to specific sequences and homologies with nonviral enzymes.

1986 • 483 citations

Structure of Ribonuclease H Phased at 2 Å Resolution by MAD Analysis of the Selenomethionyl Protein

1990 • 475 citations

Correct integration of retroviral DNA in vitro

1987 • 459 citations

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

1990 • 411 citations

[39] Unified approach to alignment and phylogenies

1990 • 398 citations

Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein.

1989 • 392 citations

A nucleoprotein complex mediates the integration of retroviral DNA.

1989 • 381 citations

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro

1990 • 350 citations

Retroviral DNA Integration Directed by HIV Integration Protein in Vitro

1990 • 346 citations

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity.

1990 • 329 citations

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

1989 • 311 citations

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

1991 • 289 citations

The 3′-5′ exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.

1991 • 279 citations

Structure of the termini of DNA intermediates in the integration of retroviral DNA: Dependence on IN function and terminal DNA sequence

1989 • 260 citations

Tn552, a novel transposable element from Staphylococcus aureus

1990 • 232 citations

Genetic recombination

1989 • 220 citations

Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis.

1990 • 176 citations

Sequence analysis of the viral core protein and the membrane-associated proteins V1 and NV2 of the flavivirus west nile virus and of the genome sequence for these proteins

1985 • 152 citations

Site-specific hydrolysis and alcoholysis of human immunodeficiency virus DNa termini mediated by the viral integrase protein

1991 • 131 citations

Pilin expression in Neisseria gonorrhoeae is under both positive and negative transcriptional control.

1988 • 103 citations

MECHANISM OF BACTERIOPHAGE MU TRANSPOSITION

1986 • 97 citations

Identification of aspartate-184 as an essential residue in the catalytic subunit of cAMP-dependent protein kinase

1988 • 70 citations

Properties of avian sarcoma-leukosis virus pp32-related pol-endonucleases produced in Escherichia coli

1988 • 55 citations

A covalent complex between retroviral integrase and nicked substrate DNA.

1991 • 46 citations