Lymphocytic Choriomeningitis Virus

‘Actively Acquired Tolerance’ of Foreign Cells

1953 • 3,103 citations

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

1998 • 1,890 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

1994 • 1,161 citations

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

1989 • 1,010 citations

Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis

1974 • 832 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response

1991 • 766 citations

Delivery Room Management of the Apparently Vigorous Meconium-stained Neonate: Results of the Multicenter, International Collaborative Trial

2000 • 719 citations

Identification of α-Dystroglycan as a Receptor for Lymphocytic Choriomeningitis Virus and Lassa Fever Virus

1998 • 675 citations

The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

1998 • 666 citations

The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection

1980 • 554 citations

The production of antibodies

1949 • 526 citations

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

2004 • 489 citations

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates

1991 • 460 citations

Cutting Edge: Rapid In Vivo Killing by Memory CD8 T Cells

2003 • 442 citations

Lymphocytic Choriomeningitis Virus

2016 • 423 citations

Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo.

1983 • 393 citations

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

1995 • 353 citations

PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION

1969 • 345 citations

The small RING finger protein Z drives arenavirus budding: Implications for antiviral strategies

2003 • 326 citations

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice

1994 • 321 citations

Central nervous system syndromes of “viral” etiology

1960 • 321 citations

Arenaviridae: The viruses and their replication

2001 • 316 citations

The Biology of Lymphocytic Choriomeningitis Infection: Virus-induced Immune Disease

1962 • 309 citations

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

1996 • 300 citations

Two Roads Diverged: Interferon α/β– and Interleukin 12–mediated Pathways in Promoting T Cell Interferon γ Responses during Viral Infection

1999 • 299 citations

Cytotoxic cells induced during lymphocytic choriomeningitis virus infection of mice. I. Characterization of natural killer cell induction

1978 • 296 citations

Experimental Lymphocytic Choriomeningitis of Monkeys and Mice Produced by a Virus Encountered in Studies of the 1933 St. Louis Encephalitis Epidemic

1934 • 293 citations

Virus-induced immunosuppression: immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression

1995 • 289 citations

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge

1996 • 287 citations

Immunosuppression and Resultant Viral Persistence by Specific Viral Targeting of Dendritic Cells

2000 • 283 citations

My Mother Caused My Illness: The Story of a Survivor of Münchausen by Proxy Syndrome

1997 • 273 citations

Ablation of CD8 and CD4 T Cell Responses by High Viral Loads

2003 • 266 citations

Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains

1983 • 241 citations

Functional analysis of T lymphocyte subsets in antiviral host defense.

1987 • 237 citations

Endoproteolytic Processing of the Lymphocytic Choriomeningitis Virus Glycoprotein by the Subtilase SKI-1/S1P

2003 • 218 citations

Phylogenetic Analysis of theArenaviridae:Patterns of Virus Evolution and Evidence for Cospeciation between Arenaviruses and Their Rodent Hosts

1997 • 211 citations

T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay?

1986 • 210 citations

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

1998 • 210 citations

T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses

1988 • 205 citations

Prevention of Type I Diabetes in Nonobese Diabetic Mice by Virus Infection

1988 • 202 citations

Viral Immunology and Immunopathology

1975 • 202 citations

A critical role for neutralizing-antibody-producing B cells, CD4⁺T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers

1997 • 202 citations

Immune response against lymphocytic choriomeningitis virus infection in mice without CD8 expression.

1991 • 201 citations

Pathologic and virologic study of fatal Lassa fever in man.

1982 • 200 citations

Lymphocytic Choriomeningitis: Production of Antibody by "Tolerant" Infected Mice

1967 • 200 citations

The completed sequence of lymphocytic choriomeningitis virus reveals a unique RNA structure and a gene for a zinc finger protein

1989 • 191 citations

Dissection of an inflammatory process induced by CD8+ T cells

1990 • 187 citations

Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response

1987 • 185 citations

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice.

1996 • 185 citations

Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence

1991 • 183 citations

Virus-Induced Alterations in Homeostasis: Alteration in Differentiated Functions of Infected Cells in Vivo

1982 • 182 citations

Experimental Studies of Arenaviral Hemorrhagic Fevers

1987 • 180 citations

Critical Role for Alpha/Beta and Gamma Interferons in Persistence of Lymphocytic Choriomeningitis Virus by Clonal Exhaustion of Cytotoxic T Cells

2001 • 177 citations

Virus-induced Transient Bone Marrow Aplasia: Major Role of Interferon-α/β during Acute Infection with the Noncytopathic Lymphocytic Choriomeningitis Virus

1997 • 173 citations

Biology and Pathogenesis of Lymphocytic Choriomeningitis Virus Infection

2002 • 172 citations

ASEPTIC MENINGITIS, A DISEASE OF DIVERSE ETIOLOGY: CLINICAL AND ETIOLOGIC STUDIES ON 854 CASES

1953 • 167 citations

Viral targeting of hematopoietic progenitors and inhibition of DC maturation as a dual strategy for immune subversion

2004 • 165 citations

Congenital Lymphocytic Choriomeningitis Virus Syndrome: A Disease That Mimics Congenital Toxoplasmosis or Cytomegalovirus Infection

1997 • 164 citations

PATHOGENESIS OF CHRONIC DISEASE ASSOCIATED WITH PERSISTENT LYMPHOCYTIC CHORIOMENINGITIS VIRAL INFECTION

1970 • 163 citations

EPIDEMIOLOGY OF LYMPHOCYTIC CHORIOMENINGITIS IN A MOUSE STOCK OBSERVED FOR FOUR YEARS

1939 • 163 citations

Principles of Animal Virology

1955 • 159 citations

Comparison of Activation versus Induction of Unresponsiveness of Virus-Specific CD4+ and CD8+ T Cells upon Acute versus Persistent Viral Infection

1998 • 159 citations

Lymphocytic choriomeningitis virus: Emerging fetal teratogen

2002 • 158 citations

Differences in Affinity of Binding of Lymphocytic Choriomeningitis Virus Strains to the Cellular Receptor α-Dystroglycan Correlate with Viral Tropism and Disease Kinetics

2001 • 158 citations

Molecular analysis of the interaction of LCMV with its cellular receptorα-dystroglycan

2001 • 156 citations

Venezuelan haemorrhagic fever

1991 • 150 citations

A Filterable Virus Recovered from White Mice

1935 • 150 citations

Organ-specific selection of viral variants during chronic infection.

1988 • 148 citations

THE EFFECT OF INDUCED CHRONIC VIRAL INFECTIONS ON THE IMMUNOLOGIC DISEASES OF NEW ZEALAND MICE

1970 • 148 citations

Viral persistencein vivothrough selection of neutralizing antibody-escape variants

2000 • 147 citations

Noncytopathic Clearance of Lymphocytic Choriomeningitis Virus from the Hepatocyte

1999 • 146 citations

Mechanisms for lymphocytic choriomeningitis virus glycoprotein cleavage, transport, and incorporation into virions

2003 • 146 citations

An Essential Role for Type 1 Interferon-γ in Terminating Persistent Viral Infection

1995 • 145 citations

PERSISTENCE OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS IN IMMUNE ANIMALS AND ITS RELATION TO IMMUNITY

1936 • 144 citations

Viral Infection of Transgenic Mice Expressing a Viral Protein in Oligodendrocytes Leads to Chronic Central Nervous System Autoimmune Disease

1996 • 140 citations

Induction or prevention of immunopathological disease by cloned cytotoxic T cell lines specific for lymphocytic choriomeningitis virus

1986 • 138 citations

Persistent Virus Infection despite Chronic Cytotoxic T-Lymphocyte Activation in Gamma Interferon-Deficient Mice Infected with Lymphocytic Choriomeningitis Virus

2000 • 136 citations

Mechanism of Lymphocytic Choriomeningitis Virus Entry into Cells

1994 • 136 citations

THE EPIDEMIOLOGY OF LYMPHOCYTIC CHORIOMENINGITIS IN WHITE MICE

1936 • 135 citations

IMMUNOPATHOGENESIS OF ACUTE CENTRAL NERVOUS SYSTEM DISEASE PRODUCED BY LYMPHOCYTIC CHORIOMENINGITIS VIRUS

1972 • 134 citations

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.

1993 • 134 citations

Human-Rodent Contact and Infection with Lymphocytic Choriomeningitis and Seoul Viruses in an Inner-City Population

1991 • 134 citations

HISTOCOMPATIBILITY-LINKED GENETIC CONTROL OF DISEASE SUSCEPTIBILITY

1973 • 131 citations

An Improved Method for Seed Germination

1935 • 128 citations

Arenoviruses: Proposed Name for a Newly Defined Virus Group

1970 • 124 citations

Arenaviruses: Genomic RNAs, Transcription, and Replication

2002 • 124 citations

Acidic pH Triggers LCMV Membrane Fusion Activity and Conformational Change in the Glycoprotein Spike

1994 • 123 citations

Lymphocytic Choriomeningitis Virus Infection and House Mouse (Mus Musculus) Distribution in Urban Baltimore

1992 • 121 citations

CD40 Ligand-Mediated Interactions Are Involved in the Generation of Memory CD8⁺Cytotoxic T Lymphocytes (CTL) but Are Not Required for the Maintenance of CTL Memory following Virus Infection

1998 • 120 citations

The Immunodepressive Action of Lymphocytic Choriomeningitis Virus in Mice

1968 • 119 citations

Mechanism of recovery from acute virus infection. I. Role of T lymphocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice.

1985 • 117 citations

MENINGITIS IN MAN CAUSED BY A FILTERABLE VIRUS

1936 • 113 citations

Protein structure of lymphocytic choriomeningitis virus: Evidence for a cell-associated precursor of the virion glycopeptides

1979 • 112 citations

The primary structure of the lymphocytic choriomeningitis virus L gene encodes a putative RNA polymerase

1989 • 111 citations

Contamination of transplantable tumors, cell lines, and monoclonal antibodies with rodent viruses.

1993 • 111 citations

Restricted expression of viral glycoprotein in cells of persistently infected mice

1982 • 108 citations

Molecular characterization of the genomic S RNA segment from lymphocytic choriomeningitis virus

1987 • 108 citations

Virus Persists in β Cells of Islets of Langerhans and Is Associated with Chemical Manifestations of Diabetes

1984 • 107 citations

Murine Virus Contaminants of Leukemia Viruses and Transplantable Tumors<xref ref-type="fn" rid="FN2">2</xref>

1972 • 107 citations

Immunofluorescence study of the carrier state and mechanism of vertical transmission in lymphocytic choriomeningitis virus infection in mice

1966 • 106 citations

Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection.

1986 • 105 citations

Intracerebral injections and the growth of viruses in the mouse brain.

1960 • 104 citations

Selective Loss of Natural Killer T Cells by Apoptosis following Infection with Lymphocytic Choriomeningitis Virus

2001 • 103 citations

Lymphocytic Choriomeningitis Outbreak Associated With Pet Hamsters

1975 • 103 citations

The V5A13.1 envelope glycoprotein deletion mutant of mouse hepatitis virus type-4 is neuroattenuated by its reduced rate of spread in the central nervous system

1992 • 103 citations

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D.

1985 • 102 citations

Immunity to viruses in B cell‐deficient mice: Influence of antibodies on virus persistence and on T cell memory

1996 • 100 citations

A SEROLOGIC SURVEY FOR VIRUSES AND MYCOPLASMA PULMONIS AMONG WILD HOUSE MICE (MUS DOMESTICUS) IN SOUTHEASTERN AUSTRALIA

1993 • 99 citations

Underwhelming the Immune Response: Effect of Slow Virus Growth on CD8⁺-T-Lymphocyte Responses

2004 • 98 citations

Lymphocytic Choriomeningitis Virus: Reemerging Central Nervous System Pathogen

2000 • 98 citations

Peripheral clonal deletion of antiviral memory CD8⁺ T cells

1993 • 96 citations

Inhibition by anti-interferon serum of lymphocytic choriomeningitis virus disease in suckling mice.

1977 • 96 citations

Virus-Induced Immunosuppression

1993 • 93 citations

Protective Effect of Neonatal Thymectomy on Mouse LCM Infection

1963 • 93 citations

Critical Role for Perforin-, Fas/FasL-, and TNFR1-Mediated Cytotoxic Pathways in Down-Regulation of Antigen-Specific T Cells during Persistent Viral Infection

2002 • 90 citations

Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon

1994 • 89 citations

Viruses as therapeutic agents. I. Treatment of nonobese insulin-dependent diabetes mice with virus prevents insulin-dependent diabetes mellitus while maintaining general immune competence.

1990 • 89 citations

Antiviral immune responses of lymphocytic choriomeningitis virus-infected mice lacking CD8+ T lymphocytes because of disruption of the beta 2-microglobulin gene

1993 • 88 citations

Differential Tissue-Specific Regulation of Antiviral CD8⁺T-Cell Immune Responses during Chronic Viral Infection

2004 • 88 citations

Protein structure of lymphocytic choriomeningitis virus: Identification of the virus structural and cell associated polypeptides

1978 • 88 citations

Complementarity in the Supramolecular Design of Arenaviruses and Retroviruses Revealed by Electron Cryomicroscopy and Image Analysis

2005 • 86 citations

CD40 Ligand Is Pivotal to Efficient Control of Virus Replication in Mice Infected with Lymphocytic Choriomeningitis Virus

1998 • 86 citations

Mechanisms of antibody-mediated protection against lymphocytic choriomeningitis virus infection: mother-to-baby transfer of humoral protection

1992 • 85 citations

LYMPHOCYTIC CHORIOMENINGITIS INFECTION OF MICE AS A MODEL FOR THE STUDY OF LATENT VIRUS INFECTION

1958 • 84 citations

Molecular basis of organ-specific selection of viral variants during chronic infection

1991 • 83 citations

Virus-triggered immune suppression in mice caused by virus-specific cytotoxic T cells.

1988 • 83 citations

Lymphocytic Choriomeningitis: Two Human Fatalities Following an Unusual Febrile Illness.

1942 • 81 citations

Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus

1995 • 81 citations

Lymphocytic Choriomeningitis Virus in Man

1975 • 81 citations

A role for transforming growth factor-beta 1 in regulating natural killer cell and T lymphocyte proliferative responses during acute infection with lymphocytic choriomeningitis virus.

1991 • 80 citations

Risks of Infection among Laboratory Rats and Mice at Major Biomedical Research Institutions

1998 • 80 citations

OUTBREAK OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTIONS IN MEDICAL CENTER PERSONNEL1

1975 • 80 citations

CD4+ T-cell–epitope escape mutant virus selected in vivo

2001 • 80 citations

Proteins of lymphocytic choriomeningitis virus: Antigenic topography of the viral glycoproteins

1986 • 78 citations

Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus.

1999 • 78 citations

Evidence of infection by viruses in small British field rodents

1980 • 78 citations

Analysis of persistent virus infections by in situ hybridization to whole-mouse sections

1984 • 78 citations

Apoptotic Regulation of T Cells and Absence of Immune Deficiency in Virus-Infected Gamma Interferon Receptor Knockout Mice

1998 • 77 citations

Fine mapping of a peptide sequence containing an antigenic site conserved among arenaviruses

1988 • 77 citations

Lymphocytic Choriomeningitis Virus: An Unrecognized Teratogenic Pathogen

1995 • 77 citations

Lymphocytic choriomeningitis virus killer T cells are lethal only in weakly disseminated murine infections.

1982 • 77 citations

Nucleotide sequence conservation at the 3′ termini of the virion RNA species of new World and Old World arenaviruses

1982 • 76 citations

Interactions between viruses and lymphocytes. I. In vivo replication of lymphocytic choriomeningitis virus in mononuclear cells during both chronic and acute viral infections.

1978 • 76 citations

Epidemic Nonmeningitic Lymphocytic-Choriomeningitis-Virus Infection

1966 • 76 citations

Arenavirus-Mediated Liver Pathology: Acute Lymphocytic Choriomeningitis Virus Infection of Rhesus Macaques Is Characterized by High-Level Interleukin-6 Expression and Hepatocyte Proliferation

2003 • 75 citations

Anti-interferon globulin inhibits the development of glomerulonephritis in mice infected at birth with lymphocytic choriomeningitis virus.

1978 • 74 citations

Fine Structure Analysis of Pichinde Virus Nucleocapsids

1983 • 73 citations

Lymphocytic choriomeningitis virus: pathogenesis of acute central nervous system disease.

1971 • 72 citations

Lymphocytic Choriomeningitis Outbreak Associated With Nude Mice in a Research Institute

1992 • 71 citations

The Role of CD4⁺ T Cells in Cell‐Mediated Immunity to LCM V: Studies in MHC Class I and Class II Deficient Mice

1994 • 71 citations

Mechanism of recovery from acute virus infection. VIII. Treatment of lymphocytic choriomeningitis virus‐infected mice with anti‐interferon‐γ monoclonal antibody blocks generation of virus‐specific cytotoxic T lymphocytes and virus elimination

1989 • 71 citations

Neutralizing epitopes of lymphocytic choriomeningitis virus are conformational and require both glycosylation and disulfide bonds for expression

1989 • 71 citations

Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.

1991 • 71 citations

Virus-Induced Immune Complex Disease: Identification of Specific Viral Antigens and Antibodies Deposited in Complexes during Chronic Lymphocytic Choriomeningitis Virus Infection

1978 • 70 citations

STUDIES ON IMMUNOLOGICAL TOLERANCE TO LCM VIRUS

1964 • 69 citations

Maintenance of memory CTL responses by T helper cells and CD40‐CD40 ligand: antibodies provide the key

2004 • 68 citations

Studies of lymphocytic choriomeningitis in mice. I. The relationship between age at inoculation and outcome of infection.

1961 • 68 citations

Infection of Dendritic Cells by Lymphocytic Choriomeningitis Virus

2003 • 67 citations

Differential presentation of the same MHC class I epitopes by fibroblasts and dendritic cells.

1998 • 66 citations

Viral infection of the thymus

1992 • 65 citations

Intracerebral Inoculation of Mice: Fate of the Inoculum

1950 • 65 citations

Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation

1992 • 64 citations

Perturbation of differentiated functions during viral infectionin Vivo I. Relationship of lymphocytic choriomeningitis virus and host strains to growth hormone deficiency

1985 • 63 citations

Immunological tolerance to viruses.

1965 • 63 citations

Virus-Induced Behavioral Alteration of Mice

1977 • 63 citations

IMMUNOPATHOLOGY OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION OF NEWBORN MICE

1968 • 62 citations

Orchitis, Parotitis and Meningoencephalitis Due to Lymphocytic-Choriomeningitis Virus

1961 • 62 citations

Age Distribution of Lymphocytic Choriomeningitis Virus Serum Antibody in Birmingham, Alabama: Evidence of a Decreased Risk of Infection

1997 • 62 citations

IMMUNOFLUORESCENT STUDIES OF THE HISTOPATHOGENESIS OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION

1964 • 61 citations

A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome

1996 • 60 citations

High resolution in situ hybridization to determine the cellular distribution of lymphocytic choriomeningitis virus RNA in the tissues of persistently infected mice: relevance to arenavirus disease and mechanisms of viral persistence

1991 • 60 citations

Severity of lymphocytic choriomeningitis virus disease in different strains of suckling mice correlates with increasing amounts of endogenous interferon.

1980 • 60 citations

Viral Persistence in Neurons Alters Synaptic Plasticity and Cognitive Functions without Destruction of Brain Cells

1996 • 59 citations

Ultrastructural localization of viral antigens in the CNS of mice persistently infected with lymphocytic choriomeningitis virus (LCMV).

1983 • 59 citations

Lymphocytic choriomeningitis virus induces a chronic wasting disease in mice lacking class I major histocompatibility complex glycoproteins

1993 • 58 citations

Antiviral antibodies attenuate T-cell-mediated immunopathology following acute lymphocytic choriomeningitis virus infection

1991 • 58 citations

Lymphocytic choriomeningitis in University Hospital personnel

1975 • 58 citations

Use of alternative receptors different than α-dystroglycan by selected isolates of lymphocytic choriomeningitis virus

2004 • 57 citations

Pathogenesis of viral infections of the fetus.

1968 • 56 citations

Some Relationships between Lymphocytic Choriomeningitis (LCM) Virus and Mice

1954 • 56 citations

Hemorrhagic fever occurs after intravenous, but not after intragastric, inoculation of rhesus macaques with lymphocytic choriomeningitis virus

2002 • 56 citations

Development of a reverse transcription-polymerase chain reaction assay for diagnosis of lymphocytic choriomeningitis virus infection and its use in a prospective surveillance study

1997 • 55 citations

Lymphocytic Choriomeningitis Virus-Induced Immunosuppression: A Virus-Induced Macrophage Defect

1976 • 54 citations

Lymphocytic-Choriomeningitis Virus in Hamster Tumor: Spread to Hamsters and Humans

1965 • 53 citations

Lymphocytic-Choriomeningitis Virus Infection Traced to a Pet Hamster

1974 • 53 citations

Involvement of CD4+Cells in Lymphocytic Choriomeningitis Virus-Induced Autoimmune Anaemia and Hypergammaglobulinaemia

1994 • 52 citations

A novel type of defective viral genome suggests a unique strategy to establish and maintain persistent lymphocytic choriomeningitis virus infections

1997 • 52 citations

Role of an Intact Splenic Microarchitecture in Early Lymphocytic Choriomeningitis Virus Production

2002 • 51 citations

Exhaustion of cytotoxic T cells during adoptive immunotherapy of virus carrier mice can be prevented by B cells or CD4+ T cells

2002 • 51 citations

Immunofluorescence study of the mechanism of resistance to superinfection in mice carrying the lymphocytic choriomeningitis virus

1966 • 50 citations

Enhanced Virus Clearance by Early Inducible Lymphocytic Choriomeningitis Virus-Neutralizing Antibodies in Immunoglobulin-Transgenic Mice

1998 • 50 citations

STUDIES ON IMMUNOLOGICAL TOLERANCE TO LCM VIRUS

1965 • 50 citations

PATHOGENESIS OF CEREBELLAR HYPOPLASIA PRODUCED BY LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION OF NEONATAL RATS

1973 • 50 citations

Competitive selection in vivo by a cell for one variant over another: implications for RNA virus quasispecies in vivo

1996 • 50 citations

A Common-Source Outbreak of Callitrichid Hepatitis in Captive Tamarins and Marmosets

1993 • 50 citations

The Pathogenesis of Lymphocytic Choriomeningitis in Mice: the Effects of Different Inoculation Routes and the Footpad Response

1963 • 49 citations

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.

1994 • 49 citations

Suppression of Lymphocytic Choriomeningitis Virus—Induced Growth Hormone Deficiency Syndrome by Disease-Negative Virus Variants

1996 • 48 citations

Lymphocytic choriomeningitis virus infection in fetal, newborn, and young adult Syrian hamsters (Mesocricetus auratus)

1976 • 47 citations

Serologic diagnosis of human infections with lymphocytic choriomeningitis virus: Comparative evaluation of seven methods

1979 • 47 citations

Abrogation of tolerance to a chronic viral infection.

1991 • 47 citations

LABORATORY STUDIES OF A LYMPHOCYTIC CHORIOMENINGITIS VIRUS OUTBREAK IN MAN AND LABORATORY ANIMALS1

1975 • 47 citations

Pathology and immunohistochemistry of callitrichid hepatitis, an emerging disease of captive New World primates caused by lymphocytic choriomeningitis virus.

1995 • 46 citations

STUDIES ON IMMUNOLOGICAL TOLERANCE TO LCM VIRUS

1962 • 46 citations

An acquired immune suppression in mice caused by infection with lymphocytic choriomeningitis virus

1988 • 46 citations

Monoclonal antibodies to lymphocytic choriomeningitis virus react with pathogenic arenaviruses

1980 • 45 citations

Low-Affinity Cytotoxic T-Lymphocytes Require IFN-γ to Clear an Acute Viral Infection

1997 • 45 citations

Susceptibility of Different Mouse Strains to Lymphocytic Choriomeningitis Virus

1968 • 45 citations

Viruses as therapeutic agents. II. Viral reassortants map prevention of insulin-dependent diabetes mellitus to the small RNA of lymphocytic choriomeningitis virus.

1990 • 44 citations

Breakdown of blood-brain barrier function in the murine lymphocytic choriomeningitis virus infection mediated by virus-specific CD8+ T cells

1991 • 44 citations

Isolation of Ribosome-like Structures from Pichinde Virus

1975 • 43 citations

Virus-Induced Immunosuppression: A Murine Model of Susceptibility to Opportunistic Infection

1988 • 42 citations

Virus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistence

1994 • 41 citations

Consequences of a single Ir-gene defect for the pathogenesis of lymphocytic choriomeningitis

1985 • 41 citations

Perturbation of differentiated functions during viral infectionin vivo II. Viral reassortants map growth hormone defect to the S RNA of the lymphocytic choriomeningitis virus genome

1985 • 41 citations

Defects in the Immune System of Mice Infected with Lymphocytic Choriomeningitis Virus

1974 • 41 citations

Transfer of lymphocytic choriomeningitis disease in β₂-microglobulin-deficient mice by CD4⁺ T cells

1993 • 41 citations

Lymphocytic Choriomeningitis in a Hamster Colony Causes Infection of Hospital Personnel

1974 • 41 citations

Factors affecting the induction of persistent tolerant infection of newborn mice with lymphocytic choriomeningitis

1962 • 40 citations

The Virus-Specific and Allospecific Cytotoxic T-Lymphocyte Response to Lymphocytic Choriomeningitis Virus Is Modified in a Subpopulation of CD8⁺T Cells Coexpressing the Inhibitory Major Histocompatibility Complex Class I Receptor Ly49G2

2000 • 40 citations

Pathology and Pathogenesis of Arenavirus Infections

1987 • 39 citations

Efficiency and effectiveness of cloned virus-specific cytotoxic T lymphocytes in vivo.

1989 • 39 citations

Entry of antivirally active T lymphocytes into the thymus of virus-infected mice.

1991 • 39 citations

Studies of lymphocytic choriomeningitis in mice. II. A comparison of the immune status of newborn and adult mice surviving inoculation.

1961 • 38 citations

Antibody prevents the establishment of persistent arenavirus infection in synergy with endogenous T cells

1997 • 38 citations

The acute inflammatory process in murine lymphocytic choriomeningitis is dependent on Lyt-2+ immune T cells

1987 • 37 citations

Rebuilding an Immune-Mediated Central Nervous System Disease: Weighing the Pathogenicity of Antigen-Specific versus Bystander T Cells

2004 • 37 citations

Different isotype profiles of virus-specific antibodies in acute and persistent lymphocytic choriomeningitis virus infection in mice.

1985 • 37 citations

Seromonitoring in small laboratory animal colonies. A five year survey: 1984-1988.

1990 • 37 citations

Lymphocytic choriomeningitis in the mouse

1964 • 37 citations

The Interplay Between Lymphocytic Choriomeningitis Virus, Immune Function, and Hemopoiesis in Mice

1978 • 37 citations

The Role of Proinflammatory Cytokines in Wasting Disease During Lymphocytic Choriomeningitis Virus Infection

2002 • 37 citations

Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression

2001 • 36 citations

Mechanisms of lymphocytic choriomeningitis virus-induced hemopoietic dysfunction

1986 • 35 citations

PATHOGENS OF HOUSE MICE ON ARID BOULLANGER ISLAND AND SUBANTARCTIC MACQUARIE ISLAND, AUSTRALIA

2003 • 35 citations

Behavioral effects of persistent lymphocytic choriomeningitis virus infection in mice

1994 • 35 citations

Lytic and Turbid Plaque-Type Mutants of Lymphocytic Choriomeningitis Virus as a Cause of Neurological Disease or Persistent Infection

1971 • 35 citations

Comparison of the sensitivity of in vivo antibody production tests with in vitro PCR-based methods to detect infectious contamination of biological materials

2003 • 34 citations

Immunofluorescent Detection of Antibody to Lymphocytic Choriomeningitis Virus in Man

1966 • 34 citations

Serological evidence of murine pathogens in wild grey squirrels (Sciurus carolinensis) in North Wales

2002 • 34 citations

Fatal acute meningoencephalitis due to lymphocytic choriomeningitis virus

1973 • 33 citations

Persistent infection of some standard cell lines by lymphocytic choriomeningitis virus: transmission of infection by an intracellular agent

1983 • 33 citations

Sequence comparison of the large genomic RNA segments of two strains of lymphocytic choriomeningitis virus differing in pathogenic potential for guinea pigs.

1998 • 33 citations

The permeability of the blood-brain barrier in mice suffering from fatal lymphocytic choriomeningitis virus infection

1984 • 31 citations

Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo

1992 • 29 citations

Evidence for cytotoxic T-lymphocyte-target cell interaction in brains of mice infected intracerebrally with lymphocytic choriomeningitis virus

1983 • 29 citations

Murine hepatitis caused by lymphocytic choriomeningitis virus. I. The hepatic lesions.

1994 • 29 citations

Modulation by gamma interferon of antiviral cell-mediated immune responses in vivo

1996 • 28 citations

Epidemiologic Aspects of Lymphocytic Choriomeningitis in Man

1973 • 28 citations

DISEASE ACCOMPANYING IN UTERO VIRAL INFECTION

1972 • 28 citations

Virus-induced immune complex disease: specific anti-viral antibody and C1q binding material in the circulation during persistent lymphocytic choriomeningitis virus infection.

1980 • 28 citations

First Outbreak of Callitrichid Hepatitis in Germany: Genetic Characterization of the Causative Lymphocytic Choriomeningitis Virus Strains

2001 • 27 citations

Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. VI. Migration and activity in vivo in acute and persistent infection.

1986 • 27 citations

Observations on mice infected congenitally or neonatally with lymphocytic choriomeningitis (LCM) virus

1970 • 27 citations

PATHOLOGY OF LYMPHOCYTIC CHORIOMENINGITIS IN MICE

1946 • 26 citations

Pathological changes due to infection with the virus of lymphocytic chorio‐meningitis

1936 • 26 citations

Persistent Viral Infection of the Thyroid Gland: Alteration of Thyroid Function in the Absence of Tissue Injury*

1988 • 26 citations

Lymphocytic choriomeningitis virus-induced immunodepression: inherent defect of B and T lymphocytes

1990 • 26 citations

Comparison of three tests for the serological diagnosis of lymphocytic choriomeningitis virus infection

1975 • 26 citations

Virus-induced immune complex disease: genetic control of C1q binding complexes in the circulation of mice persistently infected with lymphocytic choriomeningitis virus.

1983 • 26 citations

Natural Killer Cells Contribute to Inflammation but Do Not Appear to be Essential for the Induction of Clinical Lymphocytic Choriomeningitis

1986 • 25 citations

Timed appearance of lymphocytic choriomeningitis virus after gastric inoculation of mice.

1997 • 25 citations

Lymphocytic choriomeningitis of the mouse

1972 • 25 citations

Contributions of host and donor T cells to the inflammatory process in murine lymphocytic choriomeningitis

1988 • 24 citations

Virus zoonoses and their potential for contamination of cell cultures.

1991 • 24 citations

Depletion of CD4+ T Cells Precipitates Immunopathology in Immunodeficient Mice Infected with a Noncytocidal Virus

2001 • 24 citations

Lymphocytic choriomeningitis: Ultrastructural pathology

1975 • 23 citations

Sequence Comparison Among Arenaviruses

1987 • 23 citations

Tissue-mediated selection of viral variants: correlation between glycoprotein mutation and growth in neuronal cells

1994 • 23 citations

Major histocompatibility complex-linked susceptibility or resistance to disease caused by a noncytopathic virus varies with the disease parameter evaluated.

1989 • 23 citations

Identification of MaTu-MX Agent as a New Strain of Lymphocytic Choriomeningitis Virus (LCMV) and Serological Indication of Horizontal Spread of LCMV in Human Population

1999 • 23 citations

Seroepidemiological Survey of Lymphocytic Choriomeningitis Virus in Wild House Mice in China with Particular Reference to Their Subspecies

1996 • 23 citations

Public versus personal serotypes of a viral quasispecies

2003 • 22 citations

Interference Between Lymphocytic Choriomeningitis and Rauscher Leukemia in Mice2

1966 • 22 citations

Murine infection with lymphocytic choriomeningitis virus following gastric inoculation

1996 • 22 citations

Mode of replication of lymphocytic choriomeningitis virus in persistently infected cultivated mouse L cells

1990 • 22 citations

LYMPHOCYTIC CHORIOMENINGITIS

1951 • 22 citations

Detection of lymphocytic choriomeningitis virus by use of fluorogenic nuclease reverse transcriptase-polymerase chain reaction analysis.

2003 • 22 citations

Systemic Disease in Peromyscus Leucopus Associated with Borrelia Burgdorferi Infection

1990 • 22 citations

Mechanisms of hemopoietic and immunological dysfunction induced by lymphocytic choriomeningitis virus

1978 • 22 citations

Transient Impaired Cell‐Mediated Tumor Immunity after Acute Infection with Lymphocytic Choriomeningitis Virus

1975 • 21 citations

Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus

1996 • 21 citations

Enhanced tumor susceptibility of immunocompetent mice infected with lymphocytic choriomeningitis virus

1990 • 21 citations

Virus persists in beta cells of islets of Langerhans and infection is associated with chemical manifestations of diabetes. II. Morphologic observations.

1985 • 20 citations

Arenavirus taxonomy: a review.

1975 • 20 citations

Lymphocytic Choriomeningitis Virus in Mouse Neoplasms

1956 • 20 citations

Immunopathologic alterations of lymphatic tissues of mice infected with lymphocytic choriomeningitis virus. II. Pathogenetic mechanism.

1981 • 20 citations

Murine lymphocytic choriomeningitis: the history of a natural cross-infection from wild to laboratory mice

1977 • 19 citations

Susceptibility of newborn mice with H-2k backgrounds to lymphocytic choriomeningitis virus infection.

1980 • 19 citations

Enzyme-linked immunosorbent assay for detection of antibody to lymphocytic choriomeningitis virus in mouse sera, with recombinant nucleoprotein as antigen.

1995 • 19 citations

Anticonvulsant Prolongation of Survival in Adult Murine Lymphocytic Choriomeningitis

1977 • 19 citations

Can LCM virus cause lymphomatosis in mice?

1962 • 19 citations

Severe and transient pancytopenia associated with a chronic arenavirus infection.

1987 • 19 citations

Persistent virus infection associated with chemical manifestations of diabetes. II. Role of viral strain, environmental insult, and host genetics.

1987 • 18 citations

Severity of glomerulonephritis induced in different strains of suckling mice by infection with lymphocytic choriomeningitis virus: Correlation with amounts of endogenous interferon and circulating immune complexes

1982 • 18 citations

Antagonistic Variant Virus Prevents Wild-type Virus-induced Lethal Immunopathology

2002 • 18 citations

The pathogenesis of cellular injury associated with persistent lcm viral infection. Abstr.

1969 • 17 citations

Immunopathologic Weight Loss in Intracranial LCMV Infection Initiated by the Anorexigenic Effects of IL-1β

2000 • 17 citations

The effects of pretreatment with x-rays on the pathogenesis of lymphocytic choriomeningitis in mice. II. The pathological histology.

1961 • 16 citations

Role of Viral Strains and Host Genes in Determining Levels of Immune Complexes in a Model System: Implications for HIV Infection

1991 • 16 citations

Infection of C3HeB/FeJ mice with the docile strain of lymphocytic choriomeningitis virus induces autoantibodies specific for erythrocyte Band 3

1997 • 15 citations

Studies on murine lymphocytic choriomeningitis within a partially infected colony

1969 • 14 citations

Two epizootics of lymphocytic choriomeningitis virus occurring in laboratory mice despite intensive monitoring programs.

1984 • 14 citations

Evidence for polyclonal B cell activation as the mechanism for LCMV-induced autoimmune hemolytic anemia

1992 • 14 citations

Disruption of Differentiated Functions during Viral Infection in Vivo

2001 • 14 citations

Activated T lymphocytes from mice infected by lymphocytic choriomeningitis virus display high affinity IL-2 receptors but do not proliferate in response to IL-2.

1991 • 13 citations

Detection of Lymphocytic Choriomeningitis Virus Antibody in Colonies of Laboratory Animals in Japan

1986 • 13 citations

Protection of CD3 δ Knockout Mice from Lymphocytic Choriomeningitis Virus-Induced Immunopathology: Implications for Viral Neuroinvasion

2000 • 13 citations

Tubulo-interstitial (TI) renal disease associated with chronic lymphocytic choriomeningitis viral infection in mice

1978 • 13 citations

The Presence of an Anti-Erythrocyte Autoantibody in C3HeB/FeJ mice after Lymphocytic Choriomeningitis Virus Infection

1991 • 12 citations

The growth, reproduction and mortality of mice made immunologically tolerant to lymphocytic choriomeningitis virus by congenital infection

1965 • 12 citations

Alterations in Pathogenesis of Experimental Lymphocytic Choriomeningitis Caused by Prepassage of the Virus Through Heterologous Host

1946 • 10 citations

Viral contamination of a subline of Toxoplasma gondii RH

1985 • 10 citations

Isolation of Lcm Virus in an Effort to Adapt Poliomyelitis Virus to Rodents

1948 • 10 citations

Immunosuppression in mice by lymphocytic choriomeningitis virus infection: Time dependence during primary and absence of effects on secondary antibody responses

1990 • 10 citations

Public, private and non-specific antibodies induced by non-cytopathic viral infections

2004 • 10 citations

Observations on “Late onset disease” and Tumor Incidence in Different Strains of Laboratory Mice infected Congenitally with LCM Virus: II. Experiments with Inbred CBA/J mice

1975 • 10 citations

Complement-Fixing Antigen from BHK-21 Cell Cultures Infected with Lymphocytic Choriomeningitis Virus

1969 • 8 citations

Origin and Fate of Lymphocytic Choriomeningitis Virus-Specific CD8+ T Cells Coexpressing the Inhibitory NK Cell Receptor Ly49G2

2004 • 7 citations

Travels along the viral–immunobiology highway

2002 • 7 citations

Lymphocytic choriomeningitis virus-induced immune dysfunction: induction of and recovery from T-cell anergy in acutely infected mice

1994 • 6 citations

Infection of Syrian hamsters with lymphocytic choriomeningitis virus: comparison of detection methods.

1982 • 6 citations

Inhibition of Mouse Tumors and Viruses by the M-P Strain of LCM Virus

1973 • 6 citations

Neutralizing Antibody Response of Guinea Pigs to Lymphocytic Choriomeningitis Virus

1974 • 6 citations

Lymphomas associated with a tolerant lymphocytic choriomeningitis virus infection in mice

1980 • 5 citations

Analysis of neutralizing antibody specificities of different strains of lymphocytic choriomeningitis virus with strain-specific immune sera

1993 • 5 citations

Lymphocytic choriomeningitis (LCM) virus carrier cell cultures in Hungarian laboratories.

1982 • 4 citations

ELISA and indirect immunofluorescence in the diagnosis of LCM virus infections.

1992 • 4 citations

Detection of Lymphocytic Choriomeningitis Virus Antibody in Murine Sera by Immunofluorescence

1969 • 3 citations

Etude sérologique sur l'incidence de virus murins dans une population de petits rongeurs sauvages (Microtus pennsylvanicus Ord, 1818)

1992 • 3 citations

Accelerated detection of lymphocytic choriomeningitis virus in diagnostic specimens

1976 • 1 citations

Energy Development in the Americas

1977 • 1 citations