Public versus personal serotypes of a viral quasispecies

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1999 • 2,206 citations

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity

2000 • 1,590 citations

Pathogenesis of Dengue: Challenges to Molecular Biology

1988 • 1,547 citations

RNA VIRUS MUTATIONS AND FITNESS FOR SURVIVAL

1997 • 1,501 citations

Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus

2000 • 1,270 citations

Vaccine-induced escape mutant of hepatitis B virus

1990 • 1,081 citations

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

1991 • 1,025 citations

The Outcome of Acute Hepatitis C Predicted by the Evolution of the Viral Quasispecies

2000 • 892 citations

Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

1992 • 712 citations

DISQUISITIONS ON ORIGINAL ANTIGENIC SIN

1966 • 568 citations

Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

1990 • 558 citations

Evolution and transmission of stable CTL escape mutations in HIV infection

2001 • 549 citations

Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera

1990 • 416 citations

Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses

1994 • 411 citations

Antibody-Dependent Enhancement of Infection and the Pathogenesis of Viral Disease

1994 • 313 citations

Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation

1998 • 274 citations

Surface gene mutants of hepatitis B virus in infants who develop acute or chronic infections despite immunoprophylaxis

1997 • 169 citations

Quasispecies Theory in Virology

2002 • 151 citations

Viral persistencein vivothrough selection of neutralizing antibody-escape variants

2000 • 147 citations

Autologous HIV-1 Neutralizing Antibodies

1992 • 147 citations

Heterogeneity of infection enhancement of dengue 2 strains by monoclonal antibodies.

1984 • 126 citations

Genetic Subtypes, Humoral Immunity, and Human Immunodeficiency Virus Type 1 Vaccine Development

2001 • 119 citations

Simian immunodeficiency virus mutants resistant to serum neutralization arise during persistent infection of rhesus monkeys

1993 • 119 citations

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice

1999 • 112 citations

Dengue Type 3 Virus in Plasma Is a Population of Closely Related Genomes: Quasispecies

2002 • 110 citations

Impairment of Cd4+ T Cell Responses during Chronic Virus Infection Prevents Neutralizing Antibody Responses against Virus Escape Mutants

2001 • 91 citations

Do escape mutants explain rapid increases in dengue casefatality rates within epidemics?

2000 • 88 citations

Neutralization of Multiple HIV-1 Isolates from a Single Subject by Autologous Sequential Sera

1990 • 87 citations

CD4+ T-cell–epitope escape mutant virus selected in vivo

2001 • 80 citations

Neutralization Escape in Human Immunodeficiency Virus Type 1–Infected Long‐Term Nonprogressors

1999 • 76 citations

Prevalence and Significance of Naturally Occurring Mutations in the Surface and Polymerase Genes of Hepatitis B Virus

1999 • 70 citations

T cell receptor usage and fine specificity of human immunodeficiency virus 1-specific cytotoxic T lymphocyte clones: analysis of quasispecies recognition reveals a dominant response directed against a minor in vivo variant.

1996 • 60 citations

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.

1994 • 49 citations

In Vivo Selection of Neutralization-Resistant Virus Variants But No Evidence of B Cell Tolerance in Lymphocytic Choriomeningitis Virus Carrier Mice Expressing a Transgenic Virus-Neutralizing Antibody

1999 • 23 citations