Maintenance of memory CTL responses by T helper cells and CD40‐CD40 ligand: antibodies provide the key

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

2001 • 5,893 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

1998 • 2,106 citations

Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function

1998 • 1,890 citations

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

2003 • 1,623 citations

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

1998 • 1,546 citations

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

2003 • 1,466 citations

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

1993 • 1,271 citations

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

2003 • 1,220 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Immune control of HIV-1 after early treatment of acute infection

2000 • 1,012 citations

Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

1998 • 733 citations

Induction of a CD8+ Cytotoxic T Lymphocyte Response by Cross-priming Requires Cognate CD4+ T Cell Help

1997 • 729 citations

Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA

1999 • 727 citations

A Role for CD40 Expression on CD8 ⁺ T Cells in the Generation of CD8 ⁺ T Cell Memory

2002 • 629 citations

Toll-like Receptors and Innate Immunity

2001 • 486 citations

Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8⁺and CD4⁺T lymphocytes

2000 • 392 citations

OX40-Deficient Mice Are Defective in Th Cell Proliferation but Are Competent in Generating B Cell and CTL Responses after Virus Infection

1999 • 320 citations

Levels of Human Immunodeficiency Virus Type 1-Specific Cytotoxic T-Lymphocyte Effector and Memory Responses Decline after Suppression of Viremia with Highly Active Antiretroviral Therapy

1999 • 310 citations

CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.

1996 • 300 citations

Analysis of 4-1BB Ligand (4-1BBL)-Deficient Mice and of Mice Lacking Both 4-1BBL and CD28 Reveals a Role for 4-1BBL in Skin Allograft Rejection and in the Cytotoxic T Cell Response to Influenza Virus

1999 • 280 citations

Inducible Costimulator Protein (Icos) Controls T Helper Cell Subset Polarization after Virus and Parasite Infection

2000 • 206 citations

A critical role for neutralizing-antibody-producing B cells, CD4⁺T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers

1997 • 202 citations

Cd40-Independent Pathways of T Cell Help for Priming of Cd8+ Cytotoxic T Lymphocytes

2000 • 201 citations

Exhaustion of CTL memory and recrudescence of viremia in lymphocytic choriomeningitis virus-infected MHC class II-deficient mice and B cell-deficient mice.

1996 • 185 citations

Comparison of Activation versus Induction of Unresponsiveness of Virus-Specific CD4+ and CD8+ T Cells upon Acute versus Persistent Viral Infection

1998 • 159 citations

CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection

1996 • 154 citations

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.

1996 • 149 citations

CD8+ T Cells Mediate CD40-independent Maturation of Dendritic Cells In Vivo

1999 • 145 citations

Toll-like receptors: how they work and what they do

2002 • 138 citations

CD8 lethargy in the absence of CD4 help

2002 • 137 citations

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without “memory T cells”?

1997 • 131 citations

CD40 Ligand-Mediated Interactions Are Involved in the Generation of Memory CD8⁺Cytotoxic T Lymphocytes (CTL) but Are Not Required for the Maintenance of CTL Memory following Virus Infection

1998 • 120 citations

Immune responses in the absence of costimulation: viruses know the trick.

1998 • 119 citations

Persistence of lymphocytic choriomeningitis virus at very low levels in immune mice

1999 • 112 citations

Class II major histocompatibility complex‐restricted T cell function in CD4‐deficient mice

1994 • 102 citations

Cutting Edge Commentary: Immune Responses in the Absence of Costimulation: Viruses Know the Trick

1998 • 99 citations

Induction of protective cytotoxic T cells with viral proteins

1994 • 91 citations

Antiviral immune responses of lymphocytic choriomeningitis virus-infected mice lacking CD8+ T lymphocytes because of disruption of the beta 2-microglobulin gene

1993 • 88 citations

CD40 Ligand Is Pivotal to Efficient Control of Virus Replication in Mice Infected with Lymphocytic Choriomeningitis Virus

1998 • 86 citations

Homeostatic regulation of CD8⁺ T cells after antigen challenge in the absence of Fas (CD95)

1996 • 70 citations

Balancing protective immunity and immunopathology

2002 • 58 citations

CD8 and B cell memory: same strategy, same signals

2003 • 41 citations

T cell development in CD8-/- mice. Thymic positive selection is biased toward the helper phenotype.

1995 • 38 citations

What can we learn about human immunodeficiency virus infection from a study of lymphocytic choriomeningitis virus?

1997 • 36 citations

Naive CD8+ but not CD4+ T cells induce maturation of dendritic cells

2002 • 15 citations