Comparison of Activation versus Induction of Unresponsiveness of Virus-Specific CD4+ and CD8+ T Cells upon Acute versus Persistent Viral Infection

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1995 • 4,310 citations

HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time

1996 • 3,496 citations

Vigorous HIV-1-Specific CD4 ⁺ T Cell Responses Associated with Control of Viremia

1997 • 1,868 citations

Hepatitis B Virus Immunopathogenesis

1995 • 1,568 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

1989 • 1,010 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1984 • 884 citations

Baculovirus Expression Vectors: the Requirements for High Level Expression of Proteins, Including Glycoproteins

1987 • 677 citations

Latent Herpes Simplex Virus in Spinal Ganglia of Mice

1971 • 567 citations

Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.

1990 • 503 citations

The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis.

1995 • 483 citations

Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.

1993 • 427 citations

Virus-specific major MHC class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection

1998 • 380 citations

Lactate Dehydrogenase-Elevating Virus, Equine Arteritis Virus, and Simian Hemorrhagic Fever Virus: A New Group of Positive-Strand RNA Viruses

1992 • 352 citations

Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients

1996 • 265 citations

Functional analysis of T lymphocyte subsets in antiviral host defense.

1987 • 237 citations

T-cell-mediated immunopathology versus direct cytolysis by virus: implications for HIV and AIDS

1994 • 235 citations

T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses

1988 • 205 citations

Conditions That Induce Tolerance in Mature CD4+ T Cells

1997 • 149 citations

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.

1993 • 134 citations

Molecular definition of a major cytotoxic T-lymphocyte epitope in the glycoprotein of lymphocytic choriomeningitis virus

1988 • 125 citations

Limited capacity for tolerization of CD4+ T cells specific for a pancreatic β cell neo-antigen

1995 • 121 citations

Presentation of endogenous viral proteins in association with major histocompatibility complex class II: On the role of intracellular compartmentalization, invariant chain and the TAP transporter system

1995 • 106 citations

Peripheral clonal deletion of antiviral memory CD8⁺ T cells

1993 • 96 citations

Antiviral protection by CD8+ versus CD4+ T cells. CD8+ T cells correlating with cytotoxic activity in vitro are more efficient in antivaccinia virus protection than CD4-dependent IL.

1991 • 95 citations

Persistence of memory B cells in mice deprived of T cell help

1990 • 95 citations

Fas-dependent CD4⁺cytotoxic T-cell-mediated pathogenesis during virus infection

1996 • 72 citations

Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.

1991 • 71 citations

HIV-1 dynamics in vivo.

1995 • 59 citations

Primary antibody responses to a well-defined and unique hapten are not enhanced by preimmunization with carrier: analysis in a viral model.

1986 • 50 citations

Fewer protective cytotoxic T-cell epitopes than T-helper-cell epitopes on vesicular stomatitis virus

1993 • 37 citations

Lactate dehydrogenase-elevating virus (LDV): lifelong coexistence of virus and LDV-specific immunity.

1997 • 35 citations

T helper cell unresponsiveness: Rapid induction in antigen-transgenic and reversion in non-transgenic mice

1994 • 33 citations

Role of T helper cell precursor frequency on vesicular stomatitis virus neutralizing antibody responses in a T cell receptor β chain transgenic mouse

1995 • 14 citations