Transforming Genes and Target Cells of Murine Spleen Focus-Forming Viruses

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1984 • 2,762 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

A minute chromosome in human chronic granulocytic leukemia

1960 • 2,329 citations

Conditions controlling the proliferation of haemopoietic stem cells in vitro

1977 • 2,157 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Cellular differentiation, cytidine analogs and DNA methylation

1980 • 1,803 citations

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

1982 • 1,790 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia

1985 • 1,650 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines

1984 • 1,518 citations

The c-erb-A gene encodes a thyroid hormone receptor

1986 • 1,505 citations

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

The c-erb-A protein is a high-affinity receptor for thyroid hormone

1986 • 1,340 citations

Sequence requirements for nuclear location of simian virus 40 large-T antigen

1984 • 1,278 citations

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

Normal genetically mosaic mice produced from malignant teratocarcinoma cells.

1975 • 1,175 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

The Chromosomal Basis of Human Neoplasia

1983 • 1,121 citations

Isolation and characterization of genomic and cDNA clones of human erythropoietin

1985 • 1,101 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

Amplification of a Novel v- erb B-Related Gene in a Human Mammary Carcinoma

1985 • 1,064 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1985 • 913 citations

Transfer of Proteins Across Membranes

1981 • 894 citations

Purification of human erythropoietin.

1977 • 893 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats

1985 • 829 citations

Protein translocation across the endoplasmic reticulum

1984 • 825 citations

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

1981 • 795 citations

Growth of factor-dependent hemopoietic precursor cell lines.

1980 • 793 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

MULTIPOTENTIALITY OF SINGLE EMBRYONAL CARCINOMA CELLS.

1964 • 773 citations

CELL-FREE TRANSMISSION IN ADULT SWISS MICE OF A DISEASE HAVING THE CHARACTER OF A LEUKEMIA

1957 • 759 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

A new class of murine leukemia virus associated with development of spontaneous lymphomas.

1977 • 718 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

1982 • 706 citations

Constitutive Fragile Sites and Cancer

1984 • 693 citations

Requirement for c-ras proteins during viral oncogene transformation

1986 • 680 citations

The role of gene dosage and genetic transpositions in carcinogenesis

1981 • 670 citations

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1984 • 666 citations

Evolution of tumours and the impact of molecular oncology

1985 • 666 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Clonal origin of human tumors

1976 • 662 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Amplification of endogenous myc-related DNA sequences in a human myeloid leukaemia cell line

1982 • 630 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Purification and properties of colony-stimulating factor from mouse lung-conditioned medium.

1977 • 624 citations

Cellular Transforming Genes

1982 • 622 citations

Induction of Colonies of Hemoglobin-Synthesizing Cells by Erythropoietin In Vitro

1971 • 620 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma.

1985 • 607 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53

1984 • 606 citations

Viral oncogenes

1985 • 605 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

The p21 ras C-terminus is required for transformation and membrane association

1984 • 590 citations

Enhancer elements

1983 • 576 citations

Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.

1982 • 570 citations

Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells. Identification as granulocyte colony-stimulating factor.

1983 • 568 citations

Expression of myb, myc and fos proto-oncogenes during the differentiation of a murine myeloid leukaemia

1984 • 567 citations

The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems

1977 • 563 citations

Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.

1983 • 559 citations

Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism

1985 • 555 citations

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1983 • 553 citations

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

1984 • 550 citations

Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)

1985 • 542 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1982 • 540 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

1984 • 538 citations

CSF‐1—A mononuclear phagocyte lineage‐specific hemopoietic growth factor

1983 • 536 citations

An Unidentified Virus which causes the Rapid Production of Tumours in Mice

1964 • 535 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse

1984 • 527 citations

De novo methylation and expression of retroviral genomes during mouse embryogenesis

1982 • 524 citations

Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men

1983 • 517 citations

The Effect of Differing Demands for Blood Cell Production on DNA Synthesis by Hemopoietic Colony-Forming Cells of Mice

1965 • 515 citations

Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: evidence for a pre-CFU-S cell?

1979 • 513 citations

The neu Gene: an erb B-Homologous Gene Distinct from and Unlinked to the Gene Encoding the EGF Receptor

1985 • 513 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Retinoblastoma: Clues to Human Oncogenesis

1984 • 495 citations

A novel ras-related gene family

1985 • 487 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells

1983 • 485 citations

Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter

1986 • 480 citations

Malignant transformation of early passage rodent cells by a single mutated human oncogene

1984 • 479 citations

Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

1981 • 475 citations

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins

1984 • 471 citations

Hemopoietic colony-stimulating factors

1984 • 468 citations

Oncogenes in solid human tumours

1982 • 467 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

Genetic Control Of Murine Viral Leukemogenesis

1973 • 452 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

CYTOLOGICAL EVIDENCE FOR A RELATIONSHIP BETWEEN NORMAL HEMATOPOIETIC COLONY-FORMING CELLS AND CELLS OF THE LYMPHOID SYSTEM

1968 • 441 citations

Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism

1984 • 440 citations

Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene

1983 • 429 citations

Procedures for the purification of interleukin 3 to homogeneity.

1982 • 428 citations

Avian leukemia viruses interaction with their target cells in vivo and in vitro

1978 • 421 citations

Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues

1985 • 413 citations

Development of homozygosity for chromosome 11p markers in Wilms' tumour

1984 • 411 citations

Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies

1985 • 408 citations

Physical separation of hemopoietic stem cells from cells forming colonies in culture

1969 • 407 citations

Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry

1980 • 404 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

1984 • 403 citations

Amplification and Enhanced Expression of the Epidermal Growth Factor Receptor Gene in A431 Human Carcinoma Cells

1984 • 400 citations

A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

1983 • 396 citations

Malignant Activation of a K- ras Oncogene in Lung Carcinoma But Not in Normal Tissue of the Same Patient

1984 • 395 citations

Cloning and sequence analysis of a cDNA for rat transforming growth factor-α

1985 • 388 citations

Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus

1980 • 387 citations

Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell

1981 • 385 citations

Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene

1983 • 385 citations

Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

1983 • 381 citations

T-cell and mast cell lines respond to B-cell stimulatory factor 1.

1986 • 381 citations

Alterations of myc , myb , and ras ^Ha Proto-Oncogenes In Cancers Are Frequent and Show Clinical Correlation

1986 • 379 citations

Transient nature of early haematopoietic spleen colonies

1982 • 377 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

1985 • 372 citations

Domain structure of human glucocorticoid receptor and its relationship to the v-erb-A oncogene product

1985 • 368 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins

1985 • 365 citations

Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene

1983 • 360 citations

The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid

1982 • 357 citations

Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

1980 • 356 citations

Human Cell Hybrids: Analysis of Transformation and Tumorigenicity

1982 • 349 citations

Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites

1984 • 345 citations

The Cellular Basis of the Genetically Determined Hemopoietic Defect in Anemic Mice of Genotype Sl/Sld

1965 • 345 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

1985 • 342 citations

Intron splicing: a conserved internal signal in introns of animal pre-mRNAs.

1984 • 342 citations

Loss of a Harvey ras allele in sporadic Wilms' tumour

1984 • 336 citations

Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma Virus

1980 • 336 citations

A Virus-Induced Disease of Mice Characterized by Erythrocytopoiesis and Lymphoid Leukemia

1962 • 335 citations

Pure and mixed erythroid colony formation in vitro stimulated by spleen conditioned medium with no detectable erythropoietin.

1977 • 334 citations

Hemopoietic stem cell differentiation

1980 • 333 citations

Constitutive synthesis of interleukin-3 by leukaemia cell line WEHI-3B is due to retroviral insertion near the gene

1985 • 333 citations

Competitive repopulation: a new assay for long-term stem cell functional capacity

1980 • 332 citations

Evidence for a multistep pathogenesis of chronic myelogenous leukemia

1981 • 331 citations

Spleen-Colony Formation in Anemic Mice of Genotype WW ^V

1964 • 331 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions.

1980 • 323 citations

Transforming ras genes from human melanoma: a manifestation of tumour heterogeneity?

1984 • 322 citations

Determination of the leukaemogenicity of a murine retrovirus by sequences within the long terminal repeat

1984 • 321 citations

Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies.

1982 • 317 citations

Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses

1979 • 315 citations

Hierarchical down-modulation of hemopoietic growth factor receptors

1985 • 314 citations

Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice

1986 • 313 citations

Morphologic Responses to a Murine Erythroblastosis Virus<xref ref-type="fn" rid="FN1">2</xref>

1967 • 311 citations

Human genome contains four genes homologous to transforming genes of Harvey and Kirsten murine sarcoma viruses.

1982 • 309 citations

Stem cells in normal and leukemic hemopoiesis (Henry Stratton Lecture, 1982)

1983 • 304 citations

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.

1981 • 302 citations

Assay for friend leukemia virus: Rapid quantitative method based on enumeration of macroscopic spleen foci in mice

1964 • 297 citations

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells

1984 • 296 citations

Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures.

1985 • 296 citations

Nucleotide sequence of the simian sarcoma virus genome: demonstration that its acquired cellular sequences encode the transforming gene product p28sis.

1983 • 293 citations

Primary structure of the α-subunit of transducin and its relationship to ras proteins

1985 • 291 citations

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1986 • 291 citations

Analysis of the transforming potential of the human H-ras gene by random mutagenesis.

1984 • 290 citations

Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line.

1983 • 290 citations

Cellular origin and role of mink cell focus-forming viruses in murine thymic lymphomas

1982 • 289 citations

Growth of mouse megakaryocyte colonies in vitro.

1975 • 289 citations

Expression of the c-fms proto-oncogene during human monocytic differentiation

1985 • 288 citations

Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

1986 • 288 citations

Mutant ras-encoded proteins with altered nucleotide binding exert dominant biological effects.

1986 • 285 citations

Unique allelic restriction fragments of the human Ha-ras locus in leukocyte and tumour DNAs of cancer patients

1985 • 283 citations

Regulation of very primitive, multipotent, hemopoietic cells by hemopoietin-1

1986 • 283 citations

A cytological study of the capacity for differentiation of normal hemopoietic colony‐forming cells

1967 • 280 citations

Autocrine secretion of GM-CSF in acute myeloblastic leukemia

1986 • 280 citations

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

1984 • 277 citations

Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus

1982 • 276 citations

Sequence of the Alpha Subunit of Photoreceptor G Protein: Homologies Between Transducin, ras , and Elongation Factors

1985 • 276 citations

Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity

1985 • 273 citations

Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.

1986 • 272 citations

Nucleotide Sequence of the p21 Transforming Protein of Harvey Murine Sarcoma Virus

1982 • 272 citations

Identification of a sarcoma virus-coded phosphoprotein in nonproducer cells transformed by Kirsten or Harvey murine sarcoma virus

1979 • 270 citations

Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties

1978 • 269 citations

DNA sequences homologous to vertebrate oncogenes are conserved in Drosophila melanogaster.

1981 • 269 citations

Nucleotide sequence of the genome of a murine sarcoma virus

1981 • 267 citations

Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein

1984 • 267 citations

Acute nonlymphocytic leukemia: heterogeneity of stem cell origin

1981 • 259 citations

Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus

1982 • 256 citations

Erythropoietin sensitivity as a differentiation marker in the hemopoietic system: Studies of three erythropoietic colony responses in culture

1976 • 254 citations

THE ROLE OF ERYTHROPOIETIN IN REGULATION OF POPULATION SIZE AND CELL CYCLING OF EARLY AND LATE ERYTHROID PRECURSORS IN MOUSE BONE MARROW

1977 • 251 citations

Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster.

1985 • 251 citations

Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1

1981 • 250 citations

Studies on the Nucleic Acid Sequences of Kirsten Sarcoma Virus: a Model for Formation of a Mammalian RNA-Containing Sarcoma Virus

1973 • 249 citations

A Model for the Tertiary Structure of p21, the Product of the ras Oncogene

1985 • 248 citations

Role for the 3' end of the genome in determining disease specificity of Friend and Moloney murine leukemia viruses.

1983 • 246 citations

Activation of the Transforming Potential of a Normal Cell Sequence: A Molecular Model for Oncogenesis

1981 • 246 citations

Human transforming growth factors induce tyrosine phosphorylation of EGF receptors

1981 • 244 citations

Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera

1978 • 243 citations

NIH/3T3 cells transfected with human tumor DNA containing activated ras oncogenes express the metastatic phenotype in nude mice.

1985 • 240 citations

Distribution of cells bearing receptors for a colony-stimulating factor (CSF-1) in murine tissues.

1981 • 239 citations

The Liver as a Source of Extrarenal Erythropoietin Production

1972 • 238 citations

Growth of a pure population of mouse mast cells in vitro with conditioned medium derived from concanavalin A-stimulated splenocytes.

1981 • 238 citations

Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation

1984 • 238 citations

Anemia induces accumulation of erythropoietin mRNA in the kidney and liver.

1986 • 237 citations

The persisting (P) cell: histamine content, regulation by a T cell-derived factor, origin from a bone marrow precursor, and relationship to mast cells.

1981 • 234 citations

Evidence for the Involvement of GM-CSF and FMS in the Deletion (5q) in Myeloid Disorders

1986 • 233 citations

Studies on colony formation in vitro by mouse bone marrow cells. II. Action of colony stimulating factor

1970 • 233 citations

Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element

1982 • 232 citations

Transforming growth factor-β controls receptor levels for epidermal growth factor in NRK fibroblasts

1984 • 232 citations

Characterization of epidermal growth factor receptor gene expression in malignant and normal human cell lines.

1984 • 231 citations

DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

1981 • 231 citations

Clonal inheritance of the pattern of DNA methylation in mouse cells.

1982 • 229 citations

Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability

1984 • 228 citations

Stimulation by Granulocyte-Macrophage Colony-Stimulating Factor of Leishmania Tropica Killing by Macrophages

1979 • 227 citations

Monoclonal antibodies define differential ras gene expression in malignant and benign colonic diseases

1984 • 226 citations

Synthesis of Mouse Haemoglobin and Globin mRNA in Leukaemic Cell Cultures

1972 • 225 citations

Viral src gene products are related to the catalytic chain of mammalian cAMP-dependent protein kinase.

1982 • 225 citations

Spleen colony-forming cell as common precursor for tissue mast cells and granulocytes

1981 • 224 citations

Stimulation of macrophage plasminogen activator activity by colony‐stimulating factors

1980 • 223 citations

Neoplastic Transformation of Human Epidermal Keratinocytes by AD12-SV40 and Kirsten Sarcoma Viruses

1985 • 223 citations

Proliferative effects of purified granulocyte colony‐stimulating factor (G‐CSF) on normal mouse hemopoietic cells

1983 • 221 citations

Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes.

1983 • 221 citations

Identification of the sequence responsible for the nuclear accumulation of the influenza virus nucleoprotein in Xenopus oocytes

1985 • 220 citations

New human transforming genes detected by a tumorigenicity assay.

1984 • 217 citations

c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor

1985 • 216 citations

Acute nonlymphocytic leukemia: heterogeneity of stem cell origin

1981 • 215 citations

Binding of125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cells

1985 • 215 citations

Transfection of molecularly cloned Friend murine leukemia virus DNA yields a highly leukemogenic helper-independent type C virus

1980 • 212 citations

The ras oncogene product p21 is not a regulatory component of adenylate cyclase

1985 • 210 citations

Altered Transcription of the c- abl Oncogene in K-562 and Other Chronic Myelogenous Leukemia Cells

1984 • 209 citations

Mammalian and Yeast ras Gene Products: Biological Function in Their Heterologous Systems

1985 • 209 citations

Thymotropism of murine leukemia virus is conferred by its long terminal repeat.

1983 • 209 citations

Single-cell origin of mouse hemopoietic colonies expressing multiple lineages in variable combinations.

1983 • 209 citations

Characterization of a human colon/lung carcinoma oncogene

1983 • 208 citations

Long-term in vitro culture of murine mast cells. I. Description of a growth factor-dependent culture technique.

1981 • 208 citations

Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: Similarity in size, hydrophobicity, and charge

1982 • 207 citations

The essential cells of the hemopoietic microenvironment.

1984 • 206 citations

Origin of mink cytopathic focus-forming (MCF) viruses:Comparison with ecotropic and xenotropic murine leukemia virus genomes

1981 • 206 citations

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

1985 • 205 citations

Mutational analysis of a ras catalytic domain.

1986 • 205 citations

ras gene Amplification and malignant transformation.

1985 • 204 citations

Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus

1981 • 203 citations

Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins

1984 • 203 citations

Proviral activation of the putative oncogene Pim-1 in MuLV induced T-cell lymphomas.

1985 • 203 citations

Amino acid sequence of the alpha subunit of transducin deduced from the cDNA sequence.

1985 • 202 citations

The analysis of malignancy by cell fusion. VII. cytogenetic analysis of hybrids between malignant and diploid cells and of tumours derived from them

1977 • 201 citations

A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture

1982 • 199 citations

Transformation of Human Bronchial Epithelial Cells Transfected by Harvey ras Oncogene

1985 • 198 citations

Transduction and rearrangement of the myc gene by feline leukaemia virus in naturally occurring T-cell leukaemias

1984 • 196 citations

In vitro duplication and ‘cure’ of haemopoietic defects in genetically anaemic mice

1977 • 195 citations

Yeast and mammalian ras proteins have conserved biochemical properties

1985 • 195 citations

The Proliferative States of Mouse Granulopoietic Progenitor Cells

1970 • 195 citations

Structure and expression of the mRNA for murine granulocyte-macrophage colony stimulating factor.

1985 • 195 citations

Murine erythropoietin gene: cloning, expression, and human gene homology.

1986 • 193 citations

Characterization and partial purification of a haemopoietic cell growth factor in WEHI-3 cell conditioned medium

1983 • 192 citations

A molecular approach to leukemogenesis: mouse lymphomas contain an activated c-ras oncogene.

1984 • 192 citations

Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera

1978 • 189 citations

Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells

1980 • 188 citations

Transfection of v- ras ^H DNA into MCF-7 Human Breast Cancer Cells Bypasses Dependence on Estrogen for Tumorigenicity

1985 • 185 citations

Synergism between hemopoietic growth factors (HGFs) detected by their effects on cells bearing receptors for a lineage specific HGF: Assay of hemopoietin‐1

1985 • 184 citations

Activated Proto-onc Genes: Sufficient or Necessary for Cancer?

1985 • 182 citations

Expression of the Erythropoietin Gene

1986 • 182 citations

Lymphokine Production by Cultured Human T Cells Transformed by Human T-Cell Leukemia-Lymphoma Virus-I

1984 • 182 citations

Transformation of NIH 3T3 cells by a human c-sis cDNA clone

1984 • 181 citations

Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q− syndrome

1985 • 180 citations

Variant (6;15) translocations in murine plasmacytomas involve a chromosome 15 locus at least 72 kb from the c-myc oncogene.

1985 • 180 citations

Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes

1982 • 179 citations

Transcriptional ‘enhancers’ from SV40 and polyoma virus show a cell type preference

1982 • 177 citations

Abrogation of IL-3 and IL-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes

1985 • 176 citations

The drosophila ras oncogenes: Structure and nucleotide sequence

1984 • 175 citations

Structure-function studies of a colony stimulating factor (CSF-1).

1982 • 175 citations

Two-factor requirement for murine megakaryocyte colony formation

1982 • 175 citations

Altered gene products are associated with activation of cellular rasK genes in human lung and colon carcinomas

1983 • 175 citations

Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome.

1983 • 174 citations

Mast cell clones: a model for the analysis of cellular maturation.

1982 • 174 citations

Trisomy of chromosome 15 in spontaneous leukemia of AKR mice.

1975 • 173 citations

Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype.

1983 • 172 citations

A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virus

1984 • 171 citations

Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells.

1985 • 171 citations

Amplification of the c- myb Oncogene in a Case of Human Acute Myelogenous Leukemia

1984 • 170 citations

Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation

1984 • 170 citations

Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cells

1980 • 170 citations

DNA Rearrangement and Altered RNA Expression of the c-mybOncogene In Mouse Plasmacytoid Lymphosarcomas

1983 • 167 citations

Sequences of the A-MuLV protein needed for fibroblast and lymphoid cell transformation

1983 • 165 citations

Harvey Sarcoma Virus: A Second Murine Type C Sarcoma Virus with Rat Genetic Information

1974 • 165 citations

Human colony-stimulating factor (CSF-1) radioimmunoassay: resolution of three subclasses of human colony-stimulating factors

1981 • 164 citations

Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties.

1985 • 164 citations

Separation of the erythropoietin-responsive progenitors BFU-E and CFU-E in mouse bone marrow by unit gravity sedimentation

1976 • 162 citations

Expression of c-mos proto-oncogene transcripts in mouse tissues

1985 • 162 citations

Colony-stimulating factor (CSF) radioimmunoassay: detection of a CSF subclass stimulating macrophage production.

1979 • 162 citations

The Product of the c- fms Proto-Oncogene: a Glycoprotein with Associated Tyrosine Kinase Activity

1985 • 162 citations

Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor

1978 • 161 citations

Protein phosphorylation at tyrosine is induced by the v-erbB gene product in vivo and in vitro

1985 • 160 citations

An Inhibitor of Stem Cell Proliferation in Normal Bone Marrow

1976 • 160 citations

Autocrine growth induced by src-related oncogenes in transformed chicken myeloid cells

1984 • 159 citations

Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus

1982 • 158 citations

Biological activity of cloned Moloney sarcoma virus DNA: Terminally redundant sequences may enhance transformation efficiency.

1980 • 157 citations

THE EFFECT OF HISTOCOMPATIBILITY-2 TYPE ON RESPONSE TO THE FRIEND LEUKEMIA VIRUS IN MICE

1968 • 156 citations

Evidence for specific receptors for interleukin 3 on lymphokine-dependent cell lines established from long-term bone marrow cultures.

1984 • 155 citations

Clonal assay of mouse mast cell colonies in methylcellulose culture

1982 • 155 citations

Continuous Lines of Basophil/Mast Cells Derived from Normal Mouse Bone Marrow

1981 • 154 citations

Evidence for structured variation in self-renewal capacity within long-term bone marrow cultures.

1980 • 153 citations

Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene.

1986 • 153 citations

Self-renewal of hemopoietic stem cells during mixed colony formation in vitro.

1981 • 153 citations

Transient reversion of ras oncogene-induced cell transformation by antibodies specific for amino acid 12 of ras protein

1985 • 152 citations

Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus

1982 • 151 citations

Binding of the differentiation-inducer, granulocyte-colony-stimulating factor, to responsive but not unresponsive leukemic cell lines.

1984 • 151 citations

The tandem direct repeats within the long terminal repeat of murine leukemia viruses are the primary determinant of their leukemogenic potential

1984 • 151 citations

Interference grouping of murine leukemia viruses: A distinct receptor for the MCF-Recombinant viruses in mouse cells

1982 • 151 citations

p21 of Kirsten murine sarcoma virus is thermolabile in a viral mutant temperature sensitive for the maintenance of transformation

1979 • 150 citations

Specific binding of radioiodinated granulocyte-macrophage colony-stimulating factor to hemopoietic cells.

1985 • 149 citations

Friend murine leukemia virus-induced leukemia is associated with the formation of mink cell focus-inducing viruses and is blocked in mice expressing endogenous mink cell focus-inducing xenotropic viral envelope genes.

1981 • 149 citations

Characterization of a molecularly cloned retroviral sequence associated with Fv-4 resistance

1985 • 149 citations

Antibodies to the epidermal growth factor receptor block the biological activities of sarcoma growth factor.

1983 • 148 citations

Hematopoietic Stem Cells with High Proliferative Potential

1982 • 147 citations

Nucleotide sequences in mouse DNA and RNA specific for Moloney sarcoma virus.

1976 • 147 citations

Clonal analysis of proliferation and differentiation of paired daughter cells: action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors.

1980 • 147 citations

Clonal analysis of progenitor cell commitment to granulocyte or macrophage production

1982 • 145 citations

Proliferative kinetics and differentiation of murine blast cell colonies in culture: Evidence for variable G₀ periods and constant doubling rates of early pluripotent hemopoietic progenitors

1983 • 145 citations

T-Cell Growth Factor Gene: Lack of Expression in Human T-Cell Leukemia-Lymphoma Virus-Infected Cells

1984 • 145 citations

C-abl and bcr are rearranged in a Ph1-negative CML patient.

1985 • 144 citations

Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21

1984 • 144 citations

The v-sis/PDGF-2 transforming gene product localizes to cell membranes but is not a secretory protein.

1985 • 143 citations

Attempts at Identification of Hemopoietic Stem Cell in Mouse

1971 • 141 citations

MPLV: A retrovirus complex inducing an acute myeloproliferative leukemic disorder in adult mice

1986 • 140 citations

Friend strain of spleen focus-forming virus: a recombinant between mouse type C ecotropic viral sequences and sequences related to xenotropic virus

1977 • 140 citations

Nucleotide sequence of the envelope gene of Friend murine leukemia virus

1983 • 140 citations

A transmissible feline fibrosarcoma of viral origin.

1971 • 138 citations

Molecular cloning and sequence analysis of a ras gene from Schizosaccharomyces pombe.

1985 • 138 citations

Evidence That the v- sis Gene Product Transforms by Interaction with the Receptor for Platelet-Derived Growth Factor

1985 • 138 citations

Nucleotide Sequence Analysis of the T24 Human Bladder Carcinoma Oncogene

1983 • 137 citations

PHYSICAL SEPARATION OF HEMOPOIETIC STEM CELLS DIFFERING IN THEIR CAPACITY FOR SELF-RENEWAL

1969 • 135 citations

Isolation of transforming sequences of two human lung carcinomas: structural and functional analysis of the activated c-K-ras oncogenes.

1984 • 132 citations

Granulocyte/macrophage-, megakaryocyte-, eosinophil- and erythroid-colony-stimulating factors produced by mouse spleen cells

1980 • 132 citations

Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient.

1984 • 131 citations

New Method for Detecting Cellular Transforming Genes

1982 • 131 citations

An Activated ras ^N Gene: Detected in Late But Not Early Passage Human PA1 Teratocarcinoma Cells

1984 • 131 citations

Long-term in vitro culture of murine mast cells. II. Purification of a mast cell growth factor and its dissociation from TCGF.

1981 • 131 citations

Cell Surface Expression of v-fms-Coded Glycoproteins Is Required for Transformation

1984 • 131 citations

Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences

1985 • 130 citations

The Oncogenic Activation of Human p21 ^ras by a Novel Mechanism

1986 • 130 citations

Structure of the chromosomal gene for murine interleukin 3.

1985 • 129 citations

The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters.

1985 • 129 citations

Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte‐macrophage‐megakaryocyte (GMM) differentiation

1982 • 128 citations

Transforming Genes of Retroviruses

1980 • 127 citations

Efficient insertion of genes into the mouse germ line via retroviral vectors.

1985 • 126 citations

Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus.

1977 • 126 citations

Analysis of the env gene of a molecularly cloned and biologically active Moloney mink cell focus-forming proviral DNA

1982 • 125 citations

Spleen Focus-Forming Virus in Friend and Rauscher Leukemia Virus Preparations2

1975 • 125 citations

Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: Stimulation by endotoxin, M-CSF and multi-CSF

1985 • 124 citations

Undermethylation at the 5′ end of the albumin gene is necessary but not sufficient for albumin production by rat hepatoma cells in culture

1982 • 124 citations

Erythropoiesis in Culture

1984 • 123 citations

Molecular analysis of the envelope gene and long terminal repeat of Friend mink cell focus-inducing virus: implications for the functions of these sequences

1984 • 123 citations

Expression of genes introduced into cells by retroviral infection is more efficient than that of genes introduced into cells by DNA transfection

1984 • 121 citations

Transformation parameters in chicken fibroblasts transformed by AEV and MC29 avian leukemia viruses

1978 • 120 citations

Erythropoietin‐independent erythroid colony formation in vitro by hemopoietic cells of mice infected with friend virus

1975 • 120 citations

Kinetic Parameters of Bone Marrow Stem Cells Using In Vivo Suicide by Tritiated Thymidine or by Hydroxyurea

1973 • 120 citations

Alteration of the chemotactic response of NIH/3T3 cells to PDGF by growth factors, transformation, and tumor promoters

1984 • 120 citations

Inhibition of CFU entry into cycle by a bone marrow extract.

1977 • 120 citations

Density distribution analysis of In vivo and In vitro colony forming cells in bone marrow

1970 • 120 citations

Rapid leukemia induced by cloned Friend strain of replicating murine type-C virus Association with induction of xenotropic-related RNA sequences contained in spleen focus-forming virus

1978 • 119 citations

Similar molecular properties of granulocyte-macrophage colony-stimulating factors produced by different mouse organs in vitro and in vivo.

1979 • 119 citations

In in vitro production and cloning of the P cell, a bone marrow-derived null cell that expresses H-2 and Ia-antigens, has mast cell-like granules, and is regulated by a factor released by activated T cells.

1981 • 118 citations

Heterogeneity of in vitro colony‐ and cluster‐forming cells in the mouse marrow: Segregation by velocity sedimentation

1975 • 117 citations

Structure and sequence of the human c-sis/platelet-derived growth factor 2 (SIS/PDGF2) transcriptional unit.

1986 • 117 citations

Chromosome Changes (Trisomies #15 and 17) Associated With Tumor Progression in Leukemias Induced by Radiation Leukemia Virus2

1978 • 117 citations

Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells.

1985 • 117 citations

ELECTROPHORETIC VARIATION FOR X-CHROMOSOME-LINKED PHOSPHOGLYCERATE KINASE (PGK-1) IN THE MOUSE

1977 • 116 citations

Small Cell Carcinoma of the Lung: Macrophage-Specific Antigens Suggest Hemopoietic Stem Cell Origin

1984 • 116 citations

Regulation of a collagen gene promoter by the product of viral mos oncogene

1985 • 115 citations

Cloning of integrated Moloney sarcoma proviral DNA sequences in bacteriophage lambda.

1979 • 114 citations

PARANEOPLASTIC ERYTHROCYTOSIS AND ECTOPIC ERYTHROPOIETINS*

1974 • 114 citations

Separation of different molecular forms of macrophage‐ and granulocyte‐inducing proteins for normal and leukemic myeloid cells

1980 • 113 citations

The v-fms oncogene induces factor independence and tumorigenicity in CSF-1 dependent macrophage cell line

1986 • 113 citations

Polycythemia- and anemia-inducing erythroleukemia viruses exhibit differential erythroid transforming effects in vitro

1980 • 113 citations

Characterization and Developmental Expression of a Drosophila ras Oncogene

1985 • 111 citations

Clonal growth of carcinogen-induced enzyme-deficient preneoplastic cell populations in mouse liver.

1982 • 111 citations

Myc/Ig juxtaposition by chromosomal translocations: some new insights, puzzles and paradoxes

1985 • 111 citations

Long terminal repeat sequences impart hematopoietic transformation properties to the myeloproliferative sarcoma virus.

1985 • 110 citations

The transforming protein of Moloney murine sarcoma virus is a soluble cytoplasmic protein

1983 • 109 citations

Envelope gene sequences which encode the gp52 protein of spleen focus-forming virus are required for the induction of erythroid cell proliferation

1982 • 108 citations

Purification to apparent homogeneity of a factor stimulating the growth of multiple lineages of hemopoietic cells.

1984 • 108 citations

Specific binding of the mononuclear phagocyte colony-stimulating factor CSF-1 to the product of the v-fms oncogene.

1986 • 107 citations

The hormonal control of glycogen metabolism: The amino acid sequence at the phosphorylation site of protein phosphatase inhibitor‐1

1977 • 107 citations

Purification of hemopoietin 1: a multilineage hemopoietic growth factor.

1985 • 107 citations

Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas

1983 • 106 citations

Nonrandom loss of chromosome 15 in Syrian hamster tumours induced by v-Ha-ras plus v-myc oncogenes

1985 • 106 citations

Different recombinant murine leukemia viruses use different cell surface receptors

1984 • 105 citations

A stimulator of stem cell proliferation in regenerating bone marrow.

1977 • 105 citations

Expression of the erythropoietin gene.

1986 • 104 citations

Malignant Transformation of Erythroid Cells in Vivo by Introduction of a Nonreplicating Retrovirus Vector

1985 • 103 citations

The analysis of malignancy by cell fusion: V. further evidence of the ability of normal diploid cells to suppress malignancy

1974 • 103 citations

Continuous in vitro generation of multipotential stem cell clones from src-infected cultures

1984 • 102 citations

Biologic properties of molecularly cloned and expressed murine interleukin-3

1985 • 102 citations

Unique transforming gene in carcinogen-transformed mouse cells

1981 • 101 citations

Normal DBA/2 mouse cells synthesize a glycoprotein which interferes with MCF virus infection

1982 • 100 citations

Ribonucleic Acid Components of Murine Sarcoma and Leukemia Viruses

1973 • 100 citations

Complete Nucleotide Sequence and Organization of the Moloney Murine Sarcoma Virus Genome

1981 • 100 citations

Infectious and Selectable Retrovirus Containing an Inducible Rat Growth Hormone Minigene

1984 • 99 citations

Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice

1980 • 99 citations

Chromosomal aberrations observed in 52 mouse myeloid leukemias.

1983 • 99 citations

Chromosomal mapping of the mink cell focus-inducing and xenotropic env gene family in the mouse.

1983 • 99 citations

Isolation of murine fetal hemopoietic progenitor cells and selective fractionation of various erythroid precursors

1981 • 98 citations

Three different activated ras genes in mouse tumours; evidence for oncogene activation during progression of a mouse lymphoma.

1984 • 97 citations

Autogenous production of a hemopoietic growth factor, persisting-cell-stimulating factor, as a mechanism for transformation of bone marrow-derived cells.

1983 • 97 citations

Frequent Activation of c- kis as a Transforming Gene in Fibrosarcomas Induced by Methylcholanthrene

1983 • 97 citations

Chromosome changes (trisomy 15) in murine T‐cell leukemia induced by 7,12‐dimethylbenz(a)anthracene (DMBA)

1978 • 97 citations

A Mammalian Host-Vector System That Regulates Expression and Amplification of Transfected Genes by Temperature Induction

1985 • 95 citations

Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector.

1983 • 94 citations

Transfer of genes into embryonal carcinoma cells by retrovirus infection: efficient expression from an internal promoter.

1985 • 94 citations

Gene amplification: an example of accelerated evolution in tumorigenic cells.

1985 • 94 citations

Peritoneal exudate cells. I. Growth requirement of cells capable of forming colonies in soft agar

1974 • 93 citations

Complete nucleotide sequence of the gene for the specific glycoprotein (gp55) of Friend spleen focus-forming virus.

1983 • 93 citations

Metabolic Turnover of Human c-ras^H p21 Protein of EJ Bladder Carcinoma and Its Normal Cellular and Viral Homologs

1984 • 92 citations

Entry of murine retrovirus into mouse fibroblasts

1983 • 92 citations

B-tropic friend virus: A host-range pseudotype of spleen focus-forming virus (SFFV)

1973 • 91 citations

Functional organization of the Harvey murine sarcoma virus genome

1980 • 91 citations

A new candidate for the regulation of erythropoiesis

1982 • 91 citations

Identification of a normal vertebrate cell protein related to the p21 src of harvey murine sarcoma virus

1980 • 91 citations

Suppression of tumorigenicity in hybrids of normal and oncogene-transformed CHEF cells.

1985 • 91 citations

Envelope gene of the Friend spleen focus-forming virus: deletion and insertions in 3' gp70/p15E-encoding region have resulted in unique features in the primary structure of its protein product.

1983 • 91 citations

Isolation of a fibroblast nonproducer cell line containing the friend strain of the spleen focus-forming virus

1977 • 90 citations

Helper-independent mink cell focus-inducing strains of Friend murine type-C virus: potential relationship to the origin of replication-defective spleen focus-forming virus.

1978 • 89 citations

Fv-2 locus controls the proportion of erythropoietic progenitor cells (BFU-E) synthesizing DNA in normal mice

1980 • 89 citations

Delineation of transcriptional control signals within the Moloney murine sarcoma virus long terminal repeat.

1985 • 89 citations

Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells.

1984 • 88 citations

Activation of Dormant Genes in Specialized Cells

1984 • 88 citations

Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination

1981 • 87 citations

Autocrine growth stimulation of a human T-cell lymphoma line by interleukin 2.

1985 • 86 citations

Molecular and cell biologic aspects of erythropoiesis in long-term bone marrow cultures

1981 • 86 citations

Different murine cell lines manifest unique patterns of interference to superinfection by murine leukemia viruses

1985 • 86 citations

Generation of BALB-MuSV and Ha-MuSV by type C virus transduction of homologous transforming genes from different species

1981 • 86 citations

Activity in fetal bovine serum that stimulates erythroid colony formation in fetal mouse livers is insulinlike growth factor I.

1985 • 85 citations

Binding of iodinated multipotential colony‐stimulating factor (interleukin‐3) to murine bone marrow cells

1986 • 85 citations

Quantitative evaluation of electrophoretic allo‐ and isozyme patterns

1980 • 84 citations

The role of cells and their products in the regulation of in vitro stem cell proliferation and granulocyte development

1980 • 84 citations

Rearranged c-mos locus in a MOPC 21 murine myeloma cell line and its persistence in hybridomas

1983 • 84 citations

Transmembrane orientation of glycoproteins encoded by the v-fms oncogene

1985 • 83 citations

Envelope gene and long terminal repeat determine the different biological properties of Rauscher, Friend, and Moloney mink cell focus-inducing viruses

1985 • 82 citations

Expression of Cellular Oncogenes

1984 • 82 citations

Effect of src infection on long-term marrow cultures: Increased self-renewal of hemopoietic progenitor cells without leukemia

1984 • 81 citations

Phenotypic transformation of normal rat kidney cells in a growth‐factor‐defined medium: Induction by a neuroblastoma‐derived transforming growth factor independently of the EGF receptor

1985 • 81 citations

Interchromosomal recombination of the cellular oncogene c-myc with the immunoglobulin heavy chain locus in murine plasmacytomas is a reciprocal exchange.

1983 • 80 citations

[29] Isolation of human erythropoietin with monoclonal antibodies

1987 • 80 citations

P85 ^gag-mos encoded by ts110 Moloney murine sarcoma virus has an associated protein kinase activity

1983 • 79 citations

Stimulating factors liberated by treated bone marrow: in vitro effect on CFU kinetics.

1976 • 79 citations

Lysine residue 121 in the proposed ATP-binding site of the v-mos protein is required for transformation.

1985 • 79 citations

Emergence of tumorigenic cells during the course of Friend virus leukemias.

1981 • 78 citations

Potentials for lymphoid differentiation by cells from long term cultures of bone marrow.

1980 • 78 citations

Harvey and Kirsten sarcoma viruses promote the growth and differentiation of erythroid precursor cells in vitro

1981 • 78 citations

Thrombopoietin production by human embryonic kidney cells in culture.

1975 • 78 citations

Construction and isolation of a transforming murine retrovirus containing the src gene of Rous sarcoma virus

1983 • 77 citations

Malignant histiocytosis.Morphologic and cytochemical findings

1978 • 77 citations

Control of globin gene transcription by erythropoietin in erythroblasts from friend virus-infected mice.

1985 • 77 citations

Cloning and expression of human erythropoietin cDNA in Escherichia coli.

1984 • 77 citations

In vitro isolation of stable rat sarcoma viruses

1978 • 76 citations

Induction of erythroid leukaemia by Harvey and Kirsten sarcoma viruses

1975 • 75 citations

Purification of the platelet-derived growth factor receptor by using an anti-phosphotyrosine antibody.

1985 • 75 citations

Detection of a new type of mouse eosinophil colony by Luxol-fast-blue staining.

1980 • 75 citations

Nucleotide sequence of the two rat cellular rasH genes.

1986 • 75 citations

Colony Formation by Mouse Peritoneal Exudate Cells in vitro

1973 • 74 citations

The production of committed hemopoietic colony-forming cells from multipotential precursor cells in vitro

1982 • 74 citations

Brief Communication: Friend Leukemia: Rapid Development of Erythropoietin-Independent Hematopoietic Precursors2

1975 • 74 citations

Recovery of biologically active spleen focus-forming virus from molecularly cloned spleen focus-forming virus-pBR322 circular DNA by cotransfection with infectious type C retroviral DNA

1980 • 73 citations

Purification of Erythropoietin

1971 • 72 citations

Platelet-derived growth factor agonist activity of a secreted form of the v-sis oncogene product.

1985 • 72 citations

Effect of murine host genotype on MCF virus expression, latency, and leukemia cell type of leukemias induced by Friend murine leukemia helper virus

1983 • 72 citations

Purification of a multipotential colony-stimulating factor from pokeweed mitogen-stimulated mouse spleen cell conditioned medium.

1985 • 72 citations

The effects of thrombopoietin on megakaryocyte-cfc, megakaryocytes, and thrombopoiesis: with studies of ploidy and platelet size.

1982 • 71 citations

The molecular biology of Friend virus

1980 • 71 citations

Loss of leukemogenicity caused by mutations in the membrane glycoprotein structural gene of Friend spleen focus-forming virus.

1983 • 70 citations

Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein.

1982 • 70 citations

Heteroduplex Analysis of the Sequence Relationships Between the Genomes of Kirsten and Harvey Sarcoma Viruses, Their Respective Parental Murine Leukemia Viruses, and the Rat Endogenous 30S RNA

1979 • 70 citations

Mechanism of activation of the mouse c-mos oncogene by the LTR of an intracisternal A-particle gene.

1984 • 70 citations

Quantitative colony method for tumorigenic cells transformed by two distinct strains of Friend leukemia virus

1981 • 69 citations

Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells

1985 • 69 citations

Plasma membrane glycoproteins encoded by cloned Rauscher and Friend spleen focus-forming viruses

1980 • 68 citations

In vitro studies on lymphocyte differentiation. I. Long term in vitro culture of cells giving rise to functional lymphocytes in irradiated mice.

1978 • 68 citations

Retroviral mutants efficiently expressed in embryonal carcinoma cells.

1986 • 67 citations

Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue 12.

1984 • 66 citations

Haemopoietic stem cells are organised for use on the basis of their generation-age

1976 • 66 citations

Construction of a retrovirus capable of transducing and expressing genes in multipotential embryonic cells.

1984 • 66 citations

Cell surface expression of v-fms-coded glycoproteins is required for transformation.

1984 • 66 citations

Integration of transfected LTR sequences into the c-raf proto-oncogene: activation by promoter insertion.

1985 • 66 citations

Cellular Moloney Murine Sarcoma (c-mos) Sequences Are Hypermethylated and Transcriptionally Silent in Normal and Transformed Rodent Cells

1982 • 66 citations

Murine leukemia virus long terminal repeat sequences can enhance gene activity in a cell-type-specific manner.

1985 • 65 citations

Regulation of Erythropoiesis. XV. Neonatal Erythropoiesis and the Effect of Nephrectomy *

1964 • 65 citations

Clonal heterogeneity in colony stimulating factor production by murine T lymphocytes

1985 • 65 citations

Cancer, Genes, and Development: The Drosophila Case

1982 • 65 citations

Three laboratory strains of spleen focus-forming virus: comparison of their genomes and translational products

1980 • 65 citations

Dimethyl Sulfoxide Stimulates Tyrosine Residue Phosphorylation of Rat Liver Epidermal Growth Factor Receptor

1983 • 64 citations

<italic>Fv-4:</italic> Gene Controlling Resistance to NB-Tropic Friend Murine Leukemia Virus. Distribution in Wild Mice, Introduction Into Genetic Background of BALB/c Mice, and Mapping of Chromosomes<xref ref-type="fn" rid="FN2">2</xref>

1981 • 64 citations

Isolation of transplantable erythroleukemia cells from mice infected with helper-independent Friend murine leukemia virus

1981 • 64 citations

Early precursors in the erythroid lineage are the specific target cells of avian erythroblastosis virus in vitro

1980 • 64 citations

Nucleotide sequence and biochemical activities of the Moloney murine sarcoma virus strain HT-1 mos gene

1985 • 64 citations

Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding.

1985 • 63 citations

Isolation of human erythropoietin with monoclonal antibodies.

1984 • 63 citations

Isolation and induction of erythroleukemic cell lines with properties of erythroid progenitor burst-forming cell (BFU-E) and erythroid precursor cell (CFU-E).

1983 • 63 citations

Characterization of the env gene and long terminal repeat of molecularly cloned Friend mink cell focus-inducing virus DNA

1984 • 62 citations

Molecular and biological properties of a macrophage colony-stimulating factor from mouse yolk sacs

1978 • 62 citations

Deregulation of Interleukin-2 Receptor Gene Expression in HTLV-I-Induced Adult T-Cell Leukemia

1985 • 62 citations

Role of intron-contained sequences in formation of moloney murine leukemia virus env mRNA.

1984 • 62 citations

Viral Aetiology of Adult T-Cell Leukaemia

1985 • 62 citations

A new erythroid cell line induced by Rauscher murine leukaemia virus

1978 • 62 citations

Preparation and neutralization characteristics of an anti-CSF antibody

1975 • 62 citations

Characterization and developmental expression of a Drosophila ras oncogene.

1985 • 62 citations

Retrovirus transduction: generation of infectious retroviruses expressing dominant and selectable genes is associated with in vivo recombination and deletion events.

1983 • 61 citations

Human proto-oncogene c-mos maps to 8q11.

1985 • 60 citations

Characterization of functional domains of p21 ras by use of chimeric genes.

1985 • 60 citations

Metabolic turnover of human c-rasH p21 protein of EJ bladder carcinoma and its normal cellular and viral homologs.

1984 • 60 citations

The effect of colony stimulating factor on the synthesis of ribonucleic acid by mouse bone marrow cells in vitro

1977 • 60 citations

Virus-Induced Polycythemia in Mice: Erythropoiesis without Erythropoietin

1968 • 60 citations

Mouse c-mos oncogene activation is prevented by upstream sequences.

1984 • 60 citations

Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).

1986 • 60 citations

Host range of mink cell focus-inducing viruses

1985 • 59 citations

Activation of N-ras gene in bone marrow cells from a patient with acute myeloblastic leukaemia

1984 • 58 citations

Nucleotide Sequence of the Rasheed Rat Sarcoma Virus Oncogene: New Mutations

1983 • 58 citations

Anemia- and polycythemia-inducing isolates of Friend spleen focus-forming virus. Biological and molecular evidence for two distinct viral genomes.

1980 • 58 citations

Topography of murine leukemia virus envelope proteins: characterization of transmembrane components

1983 • 58 citations

Glucocorticoid regulation of mouse mammary tumor virus sequences in transgenic mice.

1985 • 58 citations

Stimulation of multipotential, erythroid and other murine haematopoietic progenitor cells by adherent cell lines in the absence of detectable multi-CSF (IL-3)

1985 • 58 citations

Chromosome assignments of four mouse cellular homologs of sarcoma and leukemia virus oncogenes.

1984 • 57 citations

Status of the Association of Mink Cell Focus-forming Viruses with Leukemogenesis

1980 • 57 citations

Dissociation between transformed and differentiated phenotype in rat thyroid epithelial cells after transformation with a temperature-sensitive mutant of the Kirsten murine sarcoma virus.

1983 • 57 citations

Insertion of long interspersed repeated elements at the Igh (immunoglobulin heavy chain) and Mlvi-2 (Moloney leukemia virus integration 2) loci of rats.

1985 • 56 citations

Erythroid Differentiation of Clonal Rauscher Erythroleukemia Cells in Response to Erythropoietin or Dimethyl Sulfoxide

1980 • 56 citations

Generation of glucocorticoid-responsive Moloney murine leukemia virus by insertion of regulatory sequences from murine mammary tumor virus into the long terminal repeat

1985 • 56 citations

Molecular cloning of Moloney murine sarcoma virus: arrangement of virus-related sequences within the normal mouse genome.

1979 • 56 citations

Generation of mink cell focus-forming viruses by Friend murine leukemia virus: recombination with specific endogenous proviral sequences

1984 • 56 citations

Protein stabilization explains the gag requirement for transformation of lymphoid cells by Abelson murine leukemia virus

1985 • 56 citations

Erythroleukemia induction by replication-competent type C viruses cloned from the anemia- and polycythemia-inducing isolates of Friend leukemia virus.

1980 • 55 citations

Inheritance of DNA methylation in microinjected eggs of Xenopus laevis.

1982 • 55 citations

Production of erythropoietin-like activity by a murine erythroleukemia cell line.

1983 • 55 citations

A transcriptional enhancer with specificity for erythroid cells is located in the long terminal repeat of the Friend murine leukemia virus.

1986 • 55 citations

The envelope gene and long terminal repeat sequences contribute to the pathogenic phenotype of helper-independent Friend viruses

1984 • 54 citations

Rauscher “mink cell focus-inducing” (MCF) virus causes erythroleukemia in mice: Its isolation and properties

1980 • 54 citations

Structure and Functions of the Kirsten Murine Sarcoma Virus Genome: Molecular Cloning of Biologically Active Kirsten Murine Sarcoma Virus DNA

1981 • 54 citations

Host control of susceptibility to erythroleukemia and to the types of leukemia induced by Friend murine leukemia virus: initial and late stages

1982 • 54 citations

In vitro studies of megakaryocytopoiesis in thrombocytotic disorders of man

1983 • 54 citations

Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia

1985 • 54 citations

Helper-independent and replication-defective erythroblastosis-inducing viruses contained within anemia-inducing friend virus complex (FV-A)

1980 • 53 citations

The phenotypic characteristics of simian sarcoma virus-transformed human fibroblasts suggest that the v-sis gene product acts solely as a PDGF receptor agonist in cell transformation.

1986 • 53 citations

Sequence comparisons of the anemia- and polycythemia-inducing strains of Friend spleen focus-forming virus

1985 • 53 citations

A hemopoietic cell line dependent upon a factor in pokeweed mitogen‐stimulated spleen cell conditioning medium

1980 • 53 citations

Genetic Control by the W Locus of Susceptibility to (Friend) Spleen Focus-forming Virus

1968 • 52 citations

Chromosome marker evidence for the bipotentiality of BFU-E

1980 • 52 citations

Biological, pathological and physical characterization of a possible variant of a murine sarcoma virus (Moloney)

1968 • 52 citations

Polycythaemia- and anaemia-inducing strains of spleen focus-forming virus differ in post-translational processing of envelope-related glycoproteins

1981 • 51 citations

Rapid emergence of mink cell focus-forming (MCF) virus in various mice infected with NB-tropic friend virus

1981 • 51 citations

Activation of an N-ras gene in acute myeloblastic leukemia through somatic mutation in the first exon.

1985 • 50 citations

An antigenic difference between cells forming early and late haematopoietic spleen colonies (CFU-S)

1984 • 50 citations

Long terminal repeat of friend-MCF virus contains the sequence responsible for erythroid leukemia

1985 • 49 citations

Factors Affecting the Growth and Differentiation of Haemopoietic Cells in Culture

1984 • 49 citations

Inheritance of Susceptibility to Friend Mouse Leukemia Virus

1969 • 49 citations

Maturation and regulation of megakaryocytopoiesis.

1979 • 49 citations

Model Hereditary Cancers of Man

1983 • 48 citations

Neuroblastoma cells express c-sis and produce a transforming growth factor antigenically related to the platelet-derived growth factor.

1985 • 48 citations

Retrovirus-induced expression of interleukin 2 receptors on cells of human B-cell lineage.

1984 • 48 citations

Target cells for friend virus-induced erythroid bursts in vitro

1979 • 48 citations

Friend leukaemia virus-transformed cells, unlike normal stem cells, form spleen colonies in Sl/Sld mice

1980 • 48 citations

Molecular cloning of biologically active Rauscher spleen focus-forming virus and the sequences of its env gene and long terminal repeat

1984 • 48 citations

Further characterization of the P85gag-mos-associated protein kinase activity

1984 • 47 citations

Monoclonal origin of B lymphocyte colony-forming cells in spleen colonies formed by multipotential hemopoietic stem cells

1978 • 47 citations

Ectopic peptides released by a human melanoma cell line that modulate the transformed phenotype.

1985 • 47 citations

Site-specific antibodies to human erythropoietin directed toward the NH2-terminal region.

1983 • 47 citations

The Role of the c- mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

1985 • 47 citations

Friend and Moloney murine leukemia viruses specifically recombine with different endogenous retroviral sequences to generate mink cell focus-forming viruses.

1985 • 47 citations

Extraction of Erythropoietin from Normal Kidneys*

1978 • 47 citations

Separation of Erythropoietin-sensitive Cells From Hemopoietic Spleen Colony-forming Stem Cells of Mouse Fetal Liver by Unit Gravity Sedimentation

1971 • 47 citations

Infection of immune mast cells by Harvey sarcoma virus: immortalization without loss of requirement for interleukin-3.

1985 • 46 citations

Endodeoxyribonuclease activity associated with Rauscher murine leukemia virus

1981 • 46 citations

Nonclonal hemopoietic progenitor cells detected in long-term marrow cultures from a Turner syndrome mosaic with chronic myeloid leukemia

1984 • 46 citations

Viral protein synthesis in Friend erythroleukemia cell lines

1977 • 46 citations

Study of a virus-induced myeloproliferative syndrome associated with tumor formation in mice

1980 • 46 citations

Comparison of myeloproliferative sarcoma virus with Moloney murine sarcoma virus variants by nucleotide sequencing and heteroduplex analysis

1984 • 45 citations

Isolation and characterization of a temperature-sensitive mutant of avian myeloblastosis virus.

1983 • 45 citations

Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene

1985 • 45 citations

A mos oncogene-containing retrovirus, myeloproliferative sarcoma virus, transforms rat thyroid epithelial cells and irreversibly blocks their differentiation pattern

1985 • 45 citations

The relative hydrophobicity of oncornaviral structural proteins

1978 • 45 citations

Individual BFU-E in polycythemia vera produce both erythropoietin dependent and independent progeny

1983 • 44 citations

Construction of recombinants between molecular clones of murine retrovirus MCF 247 and Akv: determinant of an in vitro host range property that maps in the long terminal repeat

1985 • 44 citations

Retroviruses induce granulocyte–macrophage colony stimulating activity in fibroblasts

1982 • 44 citations

Transformation of rat thyroid epithelial cells by kirsten murine sarcoma virus

1981 • 43 citations

Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus.

1984 • 43 citations

Induction of angiosarcoma by a c-erbB transducing virus

1985 • 43 citations

Synthesis and processing of viral proteins in Friend erythroleukemia cell lines

1978 • 43 citations

Immunoselection of mutants deficient in cell surface glycoproteins encoded by murine erythroleukemia viruses.

1980 • 42 citations

Mapping of transforming region of the Harvey murine sarcoma virus genome by using insertion-deletion mutants constructed in vitro.

1980 • 42 citations

Nature of cells forming erythroid colonies in agar after stimulation by spleen conditioned medium

1978 • 42 citations

Naturally occurring sarcoma virus of the BALB/cCr mouse.

1974 • 42 citations

Specific differentiation events induced by erythropoietin in cells infected in vitro with the anemia strain of Friend virus.

1982 • 41 citations

Long terminal repeat enhancement of v-mos transforming activity: identification of essential regions

1983 • 41 citations

Transformation of mononuclear phagocytes in vivo and malignant histiocytosis caused by a novel murine spleen focus-forming virus

1985 • 41 citations

P‐cell Stimulating Factor: Characterization, Action on Multiple Lineages of Bone‐marrow‐derived Cells and Role in Oncogenesis

1983 • 41 citations

Short-lived cytoplasmic regulators of gene expression in cell cybrids

1981 • 41 citations

Mutant S1 Alleles of Mice Affect Susceptibility to Friend Spleen Focus-Forming Virus

1968 • 40 citations

Myeloid cell transformation by ras-containing murine sarcoma viruses.

1985 • 40 citations

Effects of 5-azacytidine on methylation and expression of specific DNA sequences in C3H 10T1/2 cells.

1984 • 39 citations

Similar transforming growth factors (TGFs) produced by cells transformed by different isolates of feline sarcoma virus

1983 • 39 citations

Analysis of the expression of spleen focus-forming virus (SFFV)-related RNA and gp55, a friend and rauscher virus-specific protein

1980 • 39 citations

Detection of a molecular complex between ras proteins and transferrin receptor

1984 • 39 citations

Differential methylation of the c-H-ras gene in normal mouse cells and during skin tumour progression.

1985 • 39 citations

Interactions between purified GM‐CSF, purified erythropoietin and spleen conditioned medium on hempoietic colony formation in vitro

1979 • 38 citations

Cellular Moloney murine sarcoma (c-mos) sequences are hypermethylated and transcriptionally silent in normal and transformed rodent cells.

1982 • 38 citations

Size, subunit composition, and secondary structure of the Friend virus genome

1976 • 38 citations

Dimethylsulfoxide-induced differentiation and hemoglobin synthesis in tissue cultures of rat erythroleukemia cells transformed by 7,12-dimethylbenz(a)anthracene.

1976 • 38 citations

Reduced hormone-stimulated adenylate cyclase activity in NIH-3T3 cells expressing the EJ human bladder ras oncogene.

1986 • 37 citations

Clonal analysis of early and late stages of erythroleukemia induced by molecular clones of integrated spleen focus-forming virus.

1981 • 37 citations

Viral transfer, transcription, and rescue of a selectable myeloproliferative sarcoma virus in embryonal cell lines: expression of the mos oncogene.

1986 • 37 citations

Role of a membrane glycoprotein in friend virus-induced erythroleukemia: Studies of mutant and revertant viruses

1985 • 36 citations

The mature form of the friend spleen focus-forming virus envelope protein, gp65, is efficiently secreted from cells

1985 • 36 citations

Regulation of the Transcript for a Lysosomal Protein: Evidence for a Gene Program Modified by Platelet-Derived Growth Factor

1985 • 36 citations

Mast‐cell precursors in various haematopoietic colonies of mice produced in vivo and in vitro

1983 • 36 citations

Is erythropoietin the only factor which regulates late erythroid differentiation?

1981 • 36 citations

Induction of the autonomous stage of transformation in erythroid cells infected with SFFV: Helper virus is not required

1986 • 36 citations

Regulation of a Hybrid Gene by Glucose and Temperature in Hamster Fibroblasts

1984 • 35 citations

Analysis of translational products of Friend strain of spleen focus-forming virus

1978 • 35 citations

Pleiotropic mutants of nih 3T3 cells with altered regulation in the expression of both type I collagen and fibronectin

1985 • 35 citations

Point mutations in the U3 region of the long terminal repeat of moloney murine leukemia virus determine disease specificity of the myeloproliferative sarcoma virus

1986 • 35 citations

Effect of intron size on splicing efficiency in retroviral transcripts

1982 • 35 citations

Phenotypically Distinct Target Cells for Murine Sarcoma Virus and Murine Leukemia Virus Marrow Transformation In Vitro<xref ref-type="fn" rid="fn2">2</xref>

1979 • 35 citations

Deletion mutants of Harvey ras p21 protein reveal the absolute requirement of at least two distant regions for GTP-binding and transforming activities.

1986 • 35 citations

Release of spleen focus-forming virus (SFFV) from differentiation inducible promyelocytic leukemia cell lines transformed in vitro by friend leukemia virus

1980 • 35 citations

Transient erythropoietic spleen colonies: Effects of erythropoietin in normal and genetically anemic W/W^v mice

1975 • 35 citations

Susceptibility of BALB/c mice carrying various DBA/2 genes to development of Friend murine leukemia virus-induced erythroleukemia.

1985 • 34 citations

Characterization of G1 transit induced by the mitogenic-oncogenic viral Ki-ras gene product.

1986 • 33 citations

Relationship between the cellular resistance to friend murine leukemia virus infection and the expression of murine leukemia virus-gp70-related glycoprotein on cell surface of BALB/c-Fv-4wr mice

1986 • 33 citations

Expression of normal and activated human Ha-ras cDNAs in Saccharomyces cerevisiae.

1985 • 33 citations

Molecular cloning and characterization of a leukemia-inducing myeloproliferative sarcoma virus and two of its temperature-sensitive mutants

1984 • 33 citations

Moloney Leukaemia Virus as a Helper in retrieving Friend Virus from a Non-infectious Reticulum Cell Sarcoma

1969 • 32 citations

Cellular site and mode of Fv-2 gene action

1985 • 32 citations

Frequent site-specific deletion of coliphage lambda murine sarcoma virus recombinants and its use in the identification of a retrovirus integration site

1980 • 32 citations

Structural organization and biological activity of molecular clones of the integrated genome of a BALB/c mouse sarcoma virus

1981 • 32 citations

Comparison of the biological effects of anemia inducing and polycythemia inducing Friend virus complex

1979 • 32 citations

Reduced leukemogenicity caused by mutations in the membrane glycoprotein gene of Rauscher spleen focus-forming virus

1984 • 31 citations

Chromosomal localization of the Moloney sarcoma virus mouse cellular (c-mos) sequence

1982 • 31 citations

Murine retroviral restriction genes Fv-4 and Akvr-1 are alleles of a single locus

1983 • 31 citations

Molecular cloning of the Harvey sarcoma virus circular DNA intermediates. II. Further structural analyses

1980 • 31 citations

Effects of myeloproliferative sarcoma virus on the pluripotential stem cell and granulocyte precursor cell populations of DBA/2 mice.

1981 • 31 citations

A kinetic and clonal analysis of heterogeneity in K562 cells

1984 • 30 citations

Activation of Ha-ras p21 by substitution, deletion, and insertion mutations.

1985 • 30 citations

Leukemia induction by a new strain of Friend mink cell focus-inducing virus: synergistic effect of Friend ecotropic murine leukemia virus

1984 • 30 citations

Highly purified fibroblast-derived growth factor, an SV40-transformed fibroblast-secreted mitogen, is closely related to platelet-derived growth factor.

1985 • 30 citations

Expression of ras cellular oncogenes during development of Drosophila melanogaster.

1985 • 30 citations

Biologically active mutants with deletions in the v-mos oncogene assayed with retroviral vectors.

1985 • 29 citations

Induction of the early stages of Friend erythroleukemia with helper-free Friend spleen focus-forming virus.

1985 • 29 citations

Membrane association and defective transport of spleen focus-forming virus glycoproteins.

1983 • 29 citations

Friend disease in vitro.

1981 • 29 citations

Kinetics of erythroid precursors in mice infected with the anemic or the polycythemic strain of Friend leukemia virus

1980 • 29 citations

A transforming ras gene can provide an essential function ordinarily supplied by an endogenous ras gene.

1986 • 29 citations

Tissue tropism of a leukemogenic murine retrovirus is determined by sequences outside of the long terminal repeats.

1986 • 28 citations

Characterization of erythropoietin produced by IW32 murine erythroleukemia cells

1984 • 28 citations

Recurrent germ‐line transmission of the teratocarcinoma genome from the METT‐1 culture line to progeny in vivo

1982 • 28 citations

Target cells for avian myeloblastosis virus in embryonic yolk sac and relationship of cell differentiation to cell transformation

1984 • 28 citations

Pseudotyping of dual-tropic recombinant viruses generated by infection of mice with different ecotropic murine leukemia viruses

1985 • 28 citations

Mutant of avian erythroblastosis virus defective for erythroblast transformation: deletion in the erb portion of p75 suggests function of the protein in leukemogenesis.

1980 • 27 citations

Isolation of erythropoietin-sensitive cells from Friend virus-infected marrow cultures: characteristics of the erythropoietin response

1983 • 27 citations

Globin synthesis in friend-erythroleukemia mouse cells in protein- and lipid-free medium

1974 • 27 citations

Regression of stem-cell erythroblastic leukemia after hypophysectomy.

1972 • 27 citations

Complete c-mos(rat) nucleotide sequence: presence of conserved domains In c-mosproteins

1984 • 27 citations

Roles of helper and defective retroviral genomes in murine erythroleukemia: studies of spleen focus-forming virus in the absence of helper

1985 • 26 citations

Characterization of two populations of CFU‐S fractionated from mouse fetal liver by fluorescence‐activated cell sorting

1984 • 26 citations

Biological and biochemical differences between variants of spleen focus-forming virus can be localized to a region containing the 3' end of the envelope gene

1985 • 25 citations

Murine megakaryocytopoiesis in vitro: an analysis of culture systems used for the study of megakaryocyte colony-forming cells and of the characteristics of megakaryocyte colonies

1983 • 25 citations

Are spleen focus-forming virus sequences related to xenotropic viruses and expressed specifically in normal erythroid cells?

1978 • 25 citations

Effects of CFU-S inhibitors on murine bone marrow during Ara-C treatment—I. Effects on stem cells

1980 • 25 citations

Contribution of the gag and pol sequences to the leukemogenicity of Friend murine leukemia virus

1985 • 24 citations

Use of site-specific antipeptide antibodies to perturb the serine kinase catalytic activity of p37mos

1985 • 24 citations

Epidermal growth factor precursor is related to the translation product of the Moloney sarcoma virus oncogene mos.

1985 • 24 citations

Fluidity of a retrovirus genome

1984 • 24 citations

Analysis of the myeloproliferative sarcoma virus genome: limited changes in the prototype lead to altered target cell specificity

1981 • 24 citations

Specific induction of erythroleukemia and myelogenous leukemia in Sprague-Dawley rats.

1982 • 24 citations

Glycosylation and intracellular transport of spleen focus-forming virus glycoproteins

1983 • 24 citations

Alternate utilization of two regulatory domains within the Moloney murine sarcoma virus long terminal repeat.

1985 • 24 citations

Inheritance of susceptibility to friend mouse leukemia virus. X. Separate genetic control of two viruses in friend virus preparation

1973 • 23 citations

Mature erythroid burst-forming units are target cells for friend virus-induced erythroid bursts friend

1981 • 23 citations

Molecular cloning of biologically active proviral DNA of the anemia-inducing strain of spleen focus-forming virus

1982 • 23 citations

Role of mink cell focus-inducing virus in leukemias induced by Friend ecotropic virus

1984 • 22 citations

Differentiation and ?renewal? of multipotential cells in vitro

1982 • 22 citations

Use of the mouse mammary tumor virus long terminal repeat to promote steroid-inducible expression of v-mos

1984 • 22 citations

An artefact explains the apparent association of the transferrin receptor with a ras gene product

1984 • 22 citations

Molecularly cloned c-mos(rat) is biologically active.

1982 • 22 citations

A host gene controlling early anaemia or polycythaemia induced by Friend erythroleukaemia virus

1982 • 22 citations

Erythropoietin, an autocrine regulator? Serum-free production of erythropoietin by cloned erythroid cell lines

1986 • 22 citations

Molecularly cloned and expressed murine T-cell gene product is biologically similar to interleukin-3.

1985 • 22 citations

The Myeloproliferative Sarcoma Virus Retains Transforming Functions after Introduction of a Dominant Selectable Marker Gene

1986 • 22 citations

Changes in genome composition of the Friend virus complex in erythroleukemia cells during the course of differentiation induced by dimethyl sulfoxide

1978 • 21 citations

A weakly pathogenic Rauscher spleen focus-forming virus mutant that lacks the carboxyl-terminal membrane anchor of its envelope glycoprotein

1985 • 21 citations

Different pseudotypesof friend spleen focus-forming virus induce polycythemia and erythropoietin-independent colony formation in serum-free medium

1981 • 21 citations

Regulation of the transcript for a lysosomal protein: evidence for a gene program modified by platelet-derived growth factor.

1985 • 20 citations

A study of added GM-CSF independent granulocyte and macrophage precursors in mouse spleen infected with myeloproliferative sarcoma virus (MPSV).

1982 • 20 citations

EGF induces receptor down‐regulation with no receptor recycling in KB cells

1985 • 20 citations

Granulocyte-macrophage colony-stimulating factor produced by an inducible murine T-cell hybridoma: molecular properties and cellular specificity.

1981 • 19 citations

Surface Antigen Expressed in Hematopoietic Cells Derived From <italic>Fv-4</italic>^{<italic>r</italic>} Mouse Strains<xref ref-type="fn" rid="FN2">2</xref>

1982 • 19 citations

Genetic Structure of Rauscher Spleen Focus-Forming Virus

1983 • 19 citations

Recombinational junctions of variants of Moloney murine sarcoma virus: generation and divergence of a mammalian transforming gene

1983 • 19 citations

Control of Proliferation and Differentiation in Cells Transformed by Friend Virus

1980 • 19 citations

Pool Size of Pluripotential Hematopoietic Stem Cells Increased in Continuous Bone Marrow Culture by Friend Spleen Focus-Forming Virus&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="fn3"&gt;3&lt;/xref&gt;

1983 • 19 citations

Analysis of pure and mixed murine mast cell colonies

1984 • 19 citations

Integration of spleen focus-forming virus proviruses in Friend tumor cells

1985 • 18 citations

Rat sarcoma virus: further analysis of individual viral isolates and the gene product

1981 • 18 citations

Virus and cell requirements for Friend virus granulocytic leukemogenesis in long-term bone marrow cultures of NIH swiss [N:NIH(S)] mice.

1980 • 18 citations

Extended self-renewal capacity of pluripotent hemopoietic stem cells: Association with persistent friend spleen focus-forming virus

1982 • 18 citations

Virus cloned from the rauscher virus complex induces erythroblastosis and thymic lymphoma

1982 • 18 citations

Increased Erythropoietin Sensitivity After In Vitro Transformation of Hematopoietic Precursors by RNA Tumor Viruses&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="fn3"&gt;3&lt;/xref&gt;

1983 • 18 citations

Perturbed hemopoiesis and the generation of multipotential stem cell clones in src-infected bone marrow cultures is an indirect or transient effect of the oncogene.

1986 • 18 citations

Identification of a spleen focus-forming virus in erythroleukemic mice infected with a wild-mouse ecotropic murine leukemia virus

1983 • 17 citations

STUDY OF CELL DEATH IN FRIEND LEUKAEMIA

1976 • 17 citations

Karyotype of Friend virus-induced mouse erythroleukemia cells

1979 • 17 citations

env-Related leukemogenic genes (gp55 genes) of two closely related polycythemic strains of friend spleen focus-forming virus possess different recombination points with an endogenous mink cell focus-forming virus env gene

1984 • 17 citations

Action of temperature-sensitive mutants of myeloproliferative sarcoma virus suggests that fibroblast-transforming and hematopoietic transforming viral properties are related

1984 • 16 citations

Helper virus is not required for in vitro erythroid transformation of hematopoietic cells by Friend virus

1980 • 16 citations

Hemopoietic stem cells: Their roles in human leukemia and certain continuous cell lines

1984 • 16 citations

Lack of retrovirus gene expression in somatic cell hybrids of friend cells and teratocarcinoma cells with a teratocarcinoma phenotype.

1984 • 15 citations

Cell surface receptors for murine leukemia viruses: Two assays and their implications

1985 • 15 citations

Hybridomas for production of monoclonal antibodies to human erythropoietin

1984 • 15 citations

Murine Leukemia Viruses: Induction of Macrophage Production of Granulocyte-Macrophage Colony-Stimulating Factor In Vitro23

1980 • 15 citations

Host Control of Sequences Specific to Friend Erythroleukemia Virus in Normal and Leukemic Mice

1980 • 15 citations

The ts110 Moloney Mouse Sarcoma Virus System: gag-mos Gene Products and Cellular Transformation

1985 • 15 citations

Restricted expression of endogenous N‐Tropic XC‐positive leukemia virus in hybrids between G and AKR mice: An effect of the Fv‐4^r gene

1980 • 15 citations

The Myeloproliferative Sarcoma Virus Causes Transformation of Erythroid Progenitor Cells In Vitro

1982 • 15 citations

The haematopoietic stem cell in Rauscher virus-induced erythroblastosis of mice

1974 • 14 citations

Incorporation of lipids into variants of Moloney sarcoma virus which produce gag-mos fusion proteins

1984 • 14 citations

Genetics of Resistance to Virus-Induced Leukemias

1983 • 14 citations

Modulation of erythropoiesis by the helper-independent Friend leukemia virus F-MuLV.

1982 • 14 citations

Myeloproliferative sarcoma virus: Its effects on erythropoiesis in adult DBA/2J mice

1983 • 13 citations

Erythropoietin responses and physical characterization of erythroid progenitor cells in rauscher virus infected BALB/c mice

1979 • 13 citations

Erythroid differentiation and commitment in rat erythroleukemia cells with hypertonic culture conditions.

1981 • 13 citations

Inheritance of susceptibility to the myeloproliferative sarcoma virus: effect of the Fv-2 locus and evidence for a myeloproliferative sarcoma virus resistance locus

1981 • 13 citations

Sequences upstream of c-mos(rat) that block RNA accumulation in mouse cells do not inhibit in vitro transcription.

1985 • 12 citations

Friend Erythroleukemia Virus Complex: Role of Viral Components in Modifying Erythroid Differentiation in Mice&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="fn3"&gt;3&lt;/xref&gt;

1982 • 12 citations

Cellular regulation in friend virus induced erythroleukemia. Studies with anemic mice of genotype SI/SI(d)

1979 • 12 citations

Defective transient endogenous spleen colony formation in S1/S1^d mice

1979 • 11 citations

Differential expression of Qa-m2 alloantigen on murine hemopoietic progenitor cells. Selective enrichment for megakaryocyte progenitors.

1983 • 10 citations

Chronic infection of Fv-2-resistant hemopoietic cells by friend spleen focus-forming virus Leukemogenesis and control of stem cell differentiation by Fv-2

1982 • 10 citations

Rauscher murine leukemia virus: molecular cloning of infectious integrated proviral DNA

1982 • 10 citations

Regression of myelocytic leukemia in rats after hypophysectomy.

1984 • 10 citations

Erythroid stem cells in Rauscher virusinfected mice

1977 • 10 citations

Rauscher Spleen Focus-forming Virus: Biological Properties and Relationship to Helper Viruses

1982 • 10 citations

Myeloproliferative syndrome induced by MPSV in DBA/2 mice: presence of a mixed-colonies promoting activity (MPA) in the spleen

1983 • 9 citations

Myeloproliferative sarcoma virus stimulates pluripotent hematopoietic stem cells and provokes tumoral transformation of the hematopoietic microenvironment in vitro

1983 • 9 citations

Expression of the v-mos gene alters a Mr 55,000 protein during acute infection by Moloney murine sarcoma virus.

1986 • 9 citations

Variable expression of Qa‐m7, Qa‐m8, and Qa‐m9 antigenic determinants on primitive hemopoietic precursor cells

1985 • 9 citations

Friend leukemia: A model for the physiopathology of human chronic leukemia

1975 • 9 citations

Moloney Murine Sarcoma Virions Contain Subgenome-length mRNA-like Molecules That Direct the Synthesis of Sarcoma-specific Polypeptides In Vitro

1980 • 8 citations

Factors affecting the generation of mast cells from multipotential colony‐forming cells

1984 • 8 citations

Myeloproliferative sarcoma virus (MPSV), a new tool for the study of hematopoiesis.

1981 • 8 citations

Cas spleen focus-forming virus. II. Further biological and biochemical characterization

1983 • 7 citations

Factors altering the ability of multipotential hemopoietic colony-forming cells to self-generate or form progenitor cells

1983 • 7 citations

Rat cells infected with anemia-inducing Friend leukemia virus contain integrated replication-competent but not defective proviral genomes.

1985 • 7 citations

Cell-surface Antigens of Abelson and Friend Murine Leukemia Viruses and of Hematopoietic Differentiation

1980 • 7 citations

Friend viral pathogenesis in C57BL/6 reversible DBA/2 allophenic mice.

1982 • 7 citations

Sequences in the long terminal repeats of the moloney murine sarcoma virus-124 genome which control transforming gene function

1984 • 6 citations

Inheritance of susceptibility to friend mouse leukemia virus. XII. Effects of the Fv‐1 locus

1974 • 6 citations

Immunoglobulin synthesis and gene rearrangements in lymphoid cells transformed by replication-competent Rauscher murine leukemia virus: transformation of B cells at various stages of differentiation.

1984 • 6 citations

Physiopathology of human and virus-induced murine leukemias.

1976 • 5 citations

Growth pattern of tumours in mice induced by murine Moloney sarcoma-virus and sarcoma-virus-transformed cells

1979 • 5 citations

Haematopoiesis In Mice Heterozygous For the W Trait: Defective Formation of Transient Endogenous Spleen Colonies

1981 • 5 citations

Molecular Cloning of Rauscher Spleen Focus-forming Virus and Biological Properties of the Cloned Virus

1984 • 5 citations

Too Many Airlines

1972 • 5 citations

Hematopoietic precursors in disease induced by the myeloproliferative sarcoma virus

1983 • 5 citations

Multipotential hemopoietic cell lines isolated from stem cell cultures infected with friend virus complex (MuLV + F-SFFV) show presence of MuLV but not F-SFFV

1986 • 5 citations

The Relationship between Genomic RNAs of Polycythaemic Forms of Spleen Focus-forming Friend Virus and its Helper Virus

1981 • 4 citations

Characterization of the early and late stages of myelomonocytic leukemia induced by friend helper‐independent virus F‐MuLV: Isolation and induction of friend myelomonocytic leukemic cell lines

1983 • 4 citations

In vitro induction of CFU-S proliferation by a non viral splenic activity from myeloproliferative sarcoma virus infected mice

1985 • 4 citations

Cellular proliferation in the spleen of DBA/2 mice infected with a myeloproliferative sarcoma virus(MPSV).

1981 • 3 citations

Reconstitution of the &lt;italic&gt;W/W&lt;/italic&gt;&lt;sup&gt;&lt;italic&gt;v&lt;/italic&gt;&lt;/sup&gt; Stem Cell Differentiation Defect by Infection With Rauscher Leukemia Virus&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;

1985 • 3 citations

Proliferation In Vivo and In Vitro of Haemopoietic Progenitor Cells Induced by AF-1, a New ras-Containing Retrovirus

1985 • 3 citations

v-abl activates embryonic globin gene expression in mouse erythroleukemia cells.

1986 • 3 citations

Hemopoietic stem cells and target cells in murine-virus-induced leukemias

1982 • 2 citations

Study of the 78A1 Isolate of Moloney Murine Sarcoma Virus. I. Molecular Cloning and Characterization

1985 • 2 citations

The hunting of the rorqual

1982 • 2 citations

Expression of Friend leukemia virus and spleen focus-forming virus-specific sequences in erythroid bursts and granulocyte-macrophage colonies from spleen and marrow of mice infected with Friend leukemia virus.

1983 • 2 citations

Study of the 78A1 Isolate of Moloney Murine Sarcoma Virus. II. Haematopoietic Tropism and Tumourigenicity

1985 • 2 citations