Cellular Transforming Genes

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

STUDIES ON THE CHEMICAL NATURE OF THE SUBSTANCE INDUCING TRANSFORMATION OF PNEUMOCOCCAL TYPES

1944 • 3,183 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

1981 • 1,611 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1977 • 931 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts

1981 • 795 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

1981 • 736 citations

Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein

1978 • 673 citations

T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes

1982 • 617 citations

Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1980 • 510 citations

Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

1982 • 494 citations

Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.

1979 • 491 citations

Human-tumor-derived cell lines contain common and different transforming genes

1981 • 455 citations

Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src).

1979 • 378 citations

Transforming activity of human tumor DNAs.

1981 • 374 citations

Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma Virus

1980 • 336 citations

Enemies within: the genesis of retrovirus oncogenes

1981 • 303 citations

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.

1981 • 302 citations

Helper-independent transformation by unintegrated Harvey sarcoma virus DNA

1978 • 277 citations

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.

1982 • 268 citations

Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product

1978 • 251 citations

Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas

1982 • 251 citations

Activation of the Transforming Potential of a Normal Cell Sequence: A Molecular Model for Oncogenesis

1981 • 246 citations

Three different human tumor cell lines contain different oncogenes

1981 • 245 citations

Transforming activity of DNA of chemically transformed and normal cells

1980 • 234 citations

Proposal for Naming Host Cell-Derived Inserts in Retrovirus Genomes

1981 • 221 citations

AKR leukemogenesis: Identification and biological significance of thymic lymphoma receptors for AKR retroviruses

1979 • 181 citations

Stage-specific transforming genes of human and mouse B- and T-lymphocyte neoplasms

1982 • 175 citations

Biological activity of cloned Moloney sarcoma virus DNA: Terminally redundant sequences may enhance transformation efficiency.

1980 • 157 citations

Homology exists among the transforming sequences of avian and feline sarcoma viruses.

1980 • 144 citations

Virus Recovery in Chicken Cells Tested with Rous Sarcoma Cell DNA

1972 • 142 citations

Activation of related transforming genes in mouse and human mammary carcinomas.

1981 • 139 citations

Two distinct candidate transforming genes of lymphoid leukosis virus-induced neoplasms

1981 • 135 citations

Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein.

1979 • 132 citations

Cellular Sequences Related to Three New onc Genes of Avian Sarcoma Virus ( fps, yes , and ros ) and Their Expression in Normal and Transformed Cells

1982 • 131 citations

Transforming genes of neoplasms induced by avian lymphoid leukosis viruses

1980 • 124 citations

Unique transforming gene in carcinogen-transformed mouse cells

1981 • 101 citations

Transformation of NIH/3T3 mouse cells by DNA of Rous sarcoma virus

1979 • 77 citations

High-frequency cotransfer of the transformed phenotype and a tumor-specific transplantation antigen by DNA from the 3-methylcholanthrene-induced Meth A sarcoma of BALB/c mice.

1981 • 54 citations

Transformation by Cloned Harvey Murine Sarcoma Virus DNA: Efficiency Increased by Long Terminal Repeat DNA

1980 • 46 citations

Transformation by subgenomic fragments of Rous sarcoma virus DNA

1980 • 45 citations

Physical map of biologically active Harvey sarcoma virus unintegrated linear DNA

1979 • 28 citations

Small, Circular, Viral DNA: Preparation and Analysis of SV40 and ϕ X174 DNA

1971 • 27 citations

Identification of an antigen associated with transforming genes of human and mouse mammary carcinomas.

1982 • 24 citations

Transfection by DNAs of avian erythroblastosis virus and avian myelocytomatosis virus strain MC29

1980 • 23 citations

[Virus production in the fibroblasts of chickens treated with deoxyribonucleic acid of rat XC cells transformed by Rous virus].

1971 • 8 citations