Expression of normal and activated human Ha-ras cDNAs in Saccharomyces cerevisiae.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Transformation of yeast.

1978 • 2,267 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

Biological properties of human c-Ha-ras1 genes mutated at codon 12

1984 • 586 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Homologies Between Signal Transducing G Proteins and ras Gene Products

1984 • 500 citations

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins

1984 • 471 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

PROTEINASE MUTANTS OF SACCHAROMYCES CEREVISIAE

1977 • 460 citations

Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry

1980 • 404 citations

Harvey murine sarcoma virus p21 ras protein: biological and biochemical significance of the cysteine nearest the carboxy terminus.

1984 • 403 citations

n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle.

1982 • 395 citations

The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid

1982 • 357 citations

Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virus

1980 • 356 citations

ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

1983 • 345 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

Guanine nucleotide-binding activity as an assay for src protein of rat-derived murine sarcoma viruses

1979 • 315 citations

Identification of the NH₂‐terminal blocking group of calcineurin B as myristic acid

1982 • 312 citations

Developmental regulation of a dictyostelium gene encoding a protein homologous to mammalian ras protein

1984 • 267 citations

Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability

1984 • 228 citations

An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins

1985 • 201 citations

Comparative biochemical properties of p21 ras molecules coded for by viral and cellular ras genes

1982 • 179 citations

The drosophila ras oncogenes: Structure and nucleotide sequence

1984 • 175 citations

The primary structure of theSaccharomyces cerevisiaegene for 3-phosphogrycerate kinase

1982 • 175 citations

Initiation of meiosis in yeast mutants defective in adenylate cyclase and cyclic AMP-dependent protein kinase

1983 • 175 citations

Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus

1982 • 151 citations

Expression of hepatitis B virus surface antigen in yeast

1983 • 138 citations

Nucleotide Sequence Analysis of the T24 Human Bladder Carcinoma Oncogene

1983 • 137 citations

Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses.

1982 • 135 citations

A guanine nucleotide-sensitive adenylate cyclase in the yeast Saccharomyces cerevisiae.

1983 • 124 citations

A product of yeast RAS2 gene is a guanine nucleotide binding protein.

1984 • 86 citations

Adenylate Cyclase Activity in Fibroblasts Transformed by Kirsten or Moloney Sarcoma Viruses

1974 • 75 citations

Studies on the levels of cyclic AMP in cells transformed by wild-type and temperature-sensitive Kirsten sarcoma virus

1974 • 73 citations

Autophosphorylation of v-Ha-ras p21 is modulated by amino acid residue 12.

1984 • 66 citations

Homologous versos heterologous gene expression in the yeast,Saccharomyces cerevisiae

1984 • 63 citations

Saccharomyces cerevisiae synthesizes proteins related to the p21 gene product of ras genes found in mammals.

1984 • 42 citations