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The Role of the c- mos Gene in the 8;21 Translocation in Human Acute Myeloblastic Leukemia

Data up to Jan 2025

Published1985
Citations47
References30

Total Citations Per Year

Abstract

References (30)

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22

1984 • 1,644 citations

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity

1984 • 913 citations

Localization of the c-abl oncogene adjacent to a translocation break point in chronic myelocytic leukaemia

1983 • 848 citations

Expression of Cellular Oncogenes in Human Malignancies

1984 • 840 citations

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

1983 • 743 citations

Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

1982 • 540 citations

Identificaton of a translocation with quinacrine fluorescence in a patient with acute leukemia.

1973 • 363 citations

Transcriptional activation of the translocated c- myc oncogene in Burkitt lymphoma

1983 • 340 citations

Properties of a Normal Mouse Cell DNA Sequence (sarc) Homologous to the src Sequence of Moloney Sarcoma Virus

1980 • 336 citations

Activation and somatic mutation of the translocated c-myc gene in Burkitt lymphoma cells

1984 • 335 citations

Two human c-onc genes are located on the long arm of chromosome 8.

1982 • 329 citations

Identification of the Constant Chromosome Regions Involved in Human Hematologic Malignant Disease

1982 • 309 citations

NOTHING TO EAT BUT FOOD.

1964 • 263 citations

Activation of the Transforming Potential of a Normal Cell Sequence: A Molecular Model for Oncogenesis

1981 • 246 citations

Activation of a cellular oncogene by DNA rearrangement: possible involvement of an IS-like element

1982 • 232 citations

An 8-kilobase abl RNA transcript in chronic myelogenous leukemia.

1984 • 210 citations

Altered Transcription of the c- abl Oncogene in K-562 and Other Chronic Myelogenous Leukemia Cells

1984 • 209 citations

Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus.

1982 • 193 citations

Activation of the c-mos oncogene in a mouse plasmacytoma by insertion of an endogenous intracisternal A-particle genome.

1983 • 174 citations

Expression of c-mos proto-oncogene transcripts in mouse tissues

1985 • 162 citations

ALTERED TRANSCRIPTION OF AN ONCOGENE IN CHRONIC MYELOID LEUKAEMIA

1984 • 156 citations

Evidence for two distinct c-src loci on human chromosomes 1 and 20

1984 • 134 citations

Cloning of integrated Moloney sarcoma proviral DNA sequences in bacteriophage lambda.

1979 • 114 citations

Rearrangement of the oncogene c-mos in mouse myeloma NSI and hybridomas

1983 • 106 citations

Translocated c-myc oncogene of Burkitt lymphoma is transcribed in plasma cells and repressed in lymphoblastoid cells.

1984 • 86 citations

Rearranged c-mos locus in a MOPC 21 murine myeloma cell line and its persistence in hybridomas

1983 • 84 citations

Molecular cloning and chromosomal mapping of a human locus related to the transforming gene of Moloney murine sarcoma virus.

1982 • 66 citations

Isolation and analysis of the 21q+ chromosome in the acute myelogenous leukemia 8;21 translocation: evidence that c-mos is not translocated.

1985 • 61 citations

Comparable complex rearrangements involving 8;21 and 9;22 translocations in leukaemia

1977 • 53 citations

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