Back to search

Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).

Data up to Jan 2025

Published1986
Citations60
References49

Total Citations Per Year

Abstract

References (49)

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Molecular Biology of the Gene

1970 • 2,116 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

1982 • 1,398 citations

Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

1983 • 1,028 citations

Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

1982 • 928 citations

Isolation of a transforming sequence from a human bladder carcinoma cell line

1982 • 776 citations

THE MOLECULAR GENETICS OF CELLULAR ONCOGENES

1984 • 765 citations

Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations

1983 • 719 citations

Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change

1982 • 706 citations

Transformation of rat cells by DNA of human adenovirus 5

1973 • 664 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

Biological properties of human c-Ha-ras1 genes mutated at codon 12

1984 • 586 citations

Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations

1983 • 553 citations

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

1984 • 550 citations

Biological and biochemical properties of human rasH genes mutated at codon 61

1986 • 538 citations

Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

1982 • 494 citations

Malignant transformation of early passage rodent cells by a single mutated human oncogene

1984 • 479 citations

Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus

1980 • 387 citations

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

1985 • 372 citations

Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene

1983 • 360 citations

Transforming ras genes from human melanoma: a manifestation of tumour heterogeneity?

1984 • 322 citations

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.

1981 • 302 citations

Analysis of the transforming potential of the human H-ras gene by random mutagenesis.

1984 • 290 citations

Oncogenes in human tumor cell lines: molecular cloning of a transforming gene from human bladder carcinoma cells.

1982 • 268 citations

Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus

1982 • 256 citations

Promoter Region of the Human Harvey ras Proto-Oncogene: Similarity to the EGF Receptor Proto-Oncogene Promoter

1985 • 233 citations

Activated Proto-onc Genes: Sufficient or Necessary for Cancer?

1985 • 182 citations

Nucleotide Sequence Analysis of the T24 Human Bladder Carcinoma Oncogene

1983 • 137 citations

An Activated ras N Gene: Detected in Late But Not Early Passage Human PA1 Teratocarcinoma Cells

1984 • 131 citations

Intramolecular integration within Moloney murine leukemia virus DNA

1981 • 122 citations

Loss of polymorphic restriction fragments in malignant melanoma: implications for tumor heterogeneity.

1985 • 106 citations

Ribonucleic Acid Components of Murine Sarcoma and Leukemia Viruses

1973 • 100 citations

Defective retrovirus-like 30S RNA species of rat and mouse cells are infectious if packaged by type C helper virus

1979 • 98 citations

Three different activated ras genes in mouse tumours; evidence for oncogene activation during progression of a mouse lymphoma.

1984 • 97 citations

Mouse cells contain two distinct ras gene mRNA species that can be translated into a p21 onc protein.

1982 • 70 citations

VARIATION IN AVIAN RETROVIRUS GENOMES*

1980 • 67 citations

Host range of murine xenotropic virus: replication in avian cells

1975 • 59 citations

Avian erythroblastosis virus E26: Nucleotide sequence of the tripartite onc gene and of the LTR, and analysis of the cellular prototype of the viral ets sequence

1984 • 59 citations

Nucleotide Sequence of the Rasheed Rat Sarcoma Virus Oncogene: New Mutations

1983 • 58 citations

Transformation and Virus Growth by Murine Sarcoma Viruses in Human Cells

1970 • 54 citations

Nucleotide sequence of two overlapping myc-related genes in avian carcinoma virus OK10 and their relation to the myc genes of other viruses and the cell.

1985 • 45 citations

Nucleotide sequence analysis of the BALB/c murine sarcoma virus transforming gene

1985 • 45 citations

The murine sarcoma virus (MSV).

1971 • 38 citations

Analysis of viral and somatic activations of the cHa-ras gene

1985 • 36 citations

Mutagenesis of avian carcinoma virus MH2: only one of two potential transforming genes (delta gag-myc) transforms fibroblasts.

1985 • 29 citations

The immediate-early enhancer element of herpes simplex virus type 1 can replace a regulatory region of the c-Ha-ras1 oncogene required for transformation

1985 • 20 citations

Defining the borders of the chicken proto-fps gene, a precursor of Fujinami sarcoma virus

1985 • 9 citations

Cited By (0)

Loading...
Harvey ras genes transform without mutant codons, apparently activated by truncation of a… (1986) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer