Regulation of Adenovirus Mrna Formation

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products

1982 • 2,114 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

1977 • 1,301 citations

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

1980 • 1,285 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region

1985 • 1,244 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

1977 • 1,138 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Enhancer-dependent expression of human kappa immunoglobulin genes introduced into mouse pre-B lymphocytes by electroporation.

1984 • 889 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

Variety in the level of gene control in eukaryotic cells

1982 • 772 citations

An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter

1985 • 763 citations

Processing of Adenovirus 2-Induced Proteins

1973 • 762 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

The molecular biology of tumor viruses

1974 • 734 citations

Three different fibronectin mRNAs arise by alternative splicing within the coding region

1983 • 713 citations

Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

1979 • 678 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

1983 • 596 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

1983 • 586 citations

Enhancer elements

1983 • 576 citations

Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing

1984 • 563 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Identification of a protein linked to the ends of adenovirus DNA

1977 • 502 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences

1983 • 477 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product

1982 • 454 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in burkitt lymphoma

1984 • 443 citations

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

1984 • 435 citations

THE PATHWAY OF EUKARYOTIC mRNA FORMATION

1983 • 429 citations

The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction

1985 • 421 citations

Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products

1985 • 417 citations

Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1979 • 395 citations

Adenovirus VAI RNA is required for efficient translation of viral mRNAs at late times after infection

1982 • 395 citations

Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene.

1985 • 391 citations

Coincidence of the promoter and capped 5′ terminus of RNA from the adenovirus 2 major late transcription unit

1978 • 390 citations

Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff

1985 • 383 citations

Specific interaction between enhancer-containing molecules and cellular components

1984 • 374 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Heterogeneity and 5′-terminal structures of the late RNAs of simian virus 40

1978 • 372 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Tumorigenicity of cells transformed by adenovirus type 12 by evasion of T-cell immunity

1983 • 353 citations

Nucleotide sequences from the adenovirus-2 genome.

1982 • 345 citations

Cell-type-specific contacts to immunoglobulin enhancers in nuclei

1985 • 341 citations

A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs

1981 • 339 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

Intricate combinatorial patterns of exon splicing generate multiple regulated troponin T isoforms from a single gene

1985 • 314 citations

The Adenovirus E1B-55K Transforming Polypeptide Modulates Transport or Cytoplasmic Stabilization of Viral and Host Cell mRNAs

1986 • 301 citations

High Stability of Messenger RNA in Growing Cultured Cells

1972 • 300 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Size heterogeneity in the 3′ end of dihydrofolate reductase messenger RNAs in mouse cells

1980 • 288 citations

Two adenovirus mRNAs have a common 5′ terminal leader sequence encoded at least 10 kb upstream from their main coding regions

1977 • 283 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing

1981 • 261 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Selection and Preliminary Characterization of Temperature-Sensitive Mutants of Type 5 Adenovirus

1972 • 248 citations

DNA replication and the early to late transition in adenovirus infection

1980 • 248 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

1981 • 237 citations

Inhibition of HeLa cell protein synthesis during adenovirus infection

1979 • 236 citations

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3′ coterminal mRNAs and five late families

1980 • 235 citations

Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport.

1985 • 234 citations

Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection.

1984 • 234 citations

DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus.

1981 • 231 citations

Transcription and RNA processing by the DNA tumour viruses

1980 • 228 citations

Identification of the gene and mRNA for the adenovirus terminal protein precursor

1981 • 227 citations

Repression of the Immunoglobulin Heavy Chain Enhancer by the Adenovirus-2 E1A Products

1985 • 223 citations

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

1984 • 221 citations

Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes

1980 • 217 citations

A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2

1976 • 216 citations

DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2.

1981 • 216 citations

Binding of α-factor pheromone to yeast a cells: Chemical and genetic evidence for an α-factor receptor

1983 • 211 citations

Polyomavirus enhancer contains multiple redundant sequence elements that activate both DNA replication and gene expression.

1985 • 206 citations

Transcription antitermination by bacteriophage lambda N gene product

1980 • 205 citations

The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA

1980 • 204 citations

Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.

1984 • 202 citations

A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro

1985 • 196 citations

Adenovirus DNA replication in vitro: characterization of a protein covalently linked to nascent DNA strands.

1980 • 190 citations

E1A 13S and 12S mRNA Products Made in Escherichia coli Both Function as Nucleus-Localized Transcription Activators but Do Not Directly Bind DNA

1985 • 190 citations

Enhancement of RNA polymerase III transcription by the E1A gene product of adenovirus

1985 • 188 citations

HeLa Cell β-Tubulin Gene Transcription Is Stimulated by Adenovirus 5 in Parallel with Viral Early Genes by an E1a-Dependent Mechanism

1984 • 187 citations

Adenovirus type 5 early region 1b gene product is required for efficient shutoff of host protein synthesis

1984 • 186 citations

Role of DNA-Dependent RNA Polymerases II and III in Transcription of the Adenovirus Genome Late in Productive Infection

1974 • 186 citations

Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome

1978 • 184 citations

The spliced structures of adenovirus 2 fiber message and the other late mRNAs

1978 • 184 citations

Nucleotide sequence analysis of the leader segments in a cloned copy of adenovirus 2 fiber mRNA

1979 • 184 citations

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

1979 • 184 citations

Control of adenovirus early gene expression: A class of immediate early products

1980 • 182 citations

Cis-acting induction of adenovirus transcription

1983 • 180 citations

Assembly of transfected DNA into chromatin: structural changes in the origin-promoter-enhancer region upon replication.

1984 • 178 citations

Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter.

1982 • 178 citations

Transcriptional ‘enhancers’ from SV40 and polyoma virus show a cell type preference

1982 • 177 citations

The structure of adenovirus 2 early nuclear and cytoplasmic RNAs

1980 • 177 citations

Adenovirus 5 DNA sequences present and RNA sequences transcribed in transformed human embryo kidney cells (HEK-Ad-5 or 293)

1979 • 176 citations

A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon.

1984 • 169 citations

E1A Control of Gene Expression Is Mediated by Sequences 5′ to the Transcriptional Starts of the Early Viral Genes

1983 • 169 citations

Controls of RNA splicing and termination in the major late adenovirus transcription unit

1981 • 169 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

A distinct RNA polymerase activity, synthesizing 5.5 s, 5 s and 4 s RNA in nuclei from adenovirus 2-infected HeLa cells

1972 • 162 citations

Cell type-specific enhancer element associated with a mouse MHC gene, Eβ

1984 • 162 citations

Functional Analysis of Adenovirus-5 Host-range Deletion Mutants Defective for Transformation of Rat Embryo Cells

1980 • 162 citations

Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs.

1981 • 162 citations

A novel mechanism of alternative RNA splicing for the developmentally regulated generation of troponin T isoforms from a single gene

1984 • 157 citations

Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNAI

1985 • 157 citations

Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2.

1980 • 157 citations

Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infection.

1985 • 155 citations

Structure and organization of the gene coding for the DNA binding protein of adenovirus type 5

1981 • 153 citations

Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products.

1984 • 153 citations

Effect of Adenovirus on Metabolism of Specific Host mRNAs: Transport Control and Specific Translational Discrimination

1983 • 151 citations

Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes.

1984 • 150 citations

Synthesis of human U1 RNA. II. Identification of two regions of the promoter essential for transcription initiation at position +1.

1984 • 148 citations

An adenovirus type 5 gene function required for initiation of viral DNA replication

1975 • 147 citations

Dissection of overlapping functions within the adenovirus type 5 E1A gene.

1984 • 146 citations

Construction of nondefective adenovirus type 5 bearing a 2.8-kilobase hepatitis B virus DNA near the right end of its genome

1985 • 144 citations

The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs.

1986 • 143 citations

Identification of the components necessary for adenovirus translational control and their utilization in cDNA expression vectors.

1985 • 142 citations

The major late adenovirus type-2 transcription unit: Termination is downstream from the last poly(A) site

1979 • 141 citations

Regulation of early adenovirus transcription: A protein product of early region 2 specifically represses region 4 transcription

1980 • 141 citations

The Polypeptides of Adenovirus-infected Cells

1972 • 141 citations

Adenovirus EIIA early promoter: transcriptional control elements and induction by the viral pre-early EIA gene, which appears to be sequence independent.

1985 • 140 citations

Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level.

1984 • 138 citations

Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells

1984 • 134 citations

Transcription of the Adenovirus Genome by an α-Amanitine-Sensitive Ribonucleic Acid Polymerase in HeLa Cells

1972 • 134 citations

The stability of early adenovirus mRNA is controlled by the viral 72 kd DNA-binding protein

1981 • 134 citations

Groups of adenovirus type 2 mRNA's derived from a large primary transcript: probable nuclear origin and possible common 3' ends

1978 • 132 citations

Proteins and messenger RNAs of the transforming region of wild-type and mutant adenoviruses

1980 • 132 citations

DNA methylation and viral gene expression in adenovirus-transformed and-infected cells

1980 • 131 citations

An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.

1985 • 131 citations

Possible role of the 72,000 dalton DNA-binding protein in regulation of adenovirus type 5 early gene expression

1978 • 124 citations

Tissue-specific expression of two mRNA species transcribed from a single vimentin gene

1983 • 123 citations

Processing and expression of early SV40 mRNA: a role for RNA conformation in splicing

1979 • 123 citations

Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species

1981 • 123 citations

A detailed analysis of an HSV-1 early promoter: sequences involved in trans-activation by viral immediate-early gene products are not early-gene specific

1984 • 117 citations

An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite

1983 • 116 citations

Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: Similar RNA levels in tumor and proliferating normal cells

1984 • 116 citations

Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro.

1984 • 114 citations

Stimulation ofin vitrotranscription by the upstream element of the adenovirus-2 major late promoter involves a specific factor

1984 • 113 citations

Promoter-proximal pausing by RNA polymerase II in vitro: transcripts shorter than 20 nucleotides are not capped.

1983 • 112 citations

Analysis of the Mouse dhfr Promoter Region: Existence of a Divergently Transcribed Gene

1985 • 112 citations

Adenovirus E1a Gene Product Expressed at High Levels in Escherichia coli Is Functional

1984 • 111 citations

The adenovirus-2 early EIIa transcription unit possesses two overlapping promoters with different sequence requirements for EIa-dependent stimulation.

1985 • 111 citations

Ribonucleoprotein structure in nascent hnRNA is nonrandom and sequence-dependent

1980 • 108 citations

RNA Synthesis and Processing in Adenovirus-infected Cells

1974 • 106 citations

Parental adenovirus DNA accumulates in nucleosome-like structures in infected cells

1979 • 104 citations

Exon mutations that affect the choice of splice sites used in processing the SV40 late transcripts

1985 • 103 citations

Isolation of type 5 adenovirus mutants with a cold-sensitive host range phenotype: Genetic evidence of an adenovirus transformation maintenance function

1982 • 103 citations

The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions

1982 • 103 citations

Analysis of nutR: A region of phage lambda required for antitermination of transcription

1982 • 102 citations

Different species of messenger RNA encode receptor and secretory IgM μ chains differing at their carboxy termini

1980 • 102 citations

Developmental variations in the splicing pattern of transcripts from the Drosophila gene encoding myosin alkali light chain result in different carboxyl-terminal amino acid sequences.

1985 • 101 citations

Control of messenger RNA concentration by differential cytoplasmic half-life

1981 • 101 citations

Processing of the adenovirus terminal protein

1981 • 99 citations

Multiple origins of transcription in the 4.5 Kb upstream of the ϵ-globin gene

1983 • 98 citations

Transcription of human histone genes in extracts from synchronized HeLa cells.

1984 • 97 citations

mRNAs from human adenovirus 2 early region 4

1984 • 95 citations

Synthesis of Virus-Specific Ribonucleic Acid in KB Cells Infected with Type 2 Adenovirus

1971 • 94 citations

Effect of Cycloheximide on RNA Metabolism Early in Productive Infection with Adenovirus 2

1974 • 94 citations

Regulation of transcription of the adenovirus EII promoter by EIa gene products: absence of sequence specificity.

1984 • 94 citations

The polypeptides of adenovirus

1969 • 93 citations

Effect of the tripartite leader on synthesis of a non-viral protein in an adenovirus 5 recombinant

1985 • 93 citations

The adenovirus major late promoter TATA box and initiation site are both necessary for transcriptionin vitro

1984 • 93 citations

Growth-Dependent Expression of Dihydrofolate Reductase mRNA from Modular cDNA Genes

1983 • 91 citations

Enhanced transformation by a simian virus 40 recombinant virus containing a Harvey murine sarcoma virus long terminal repeat.

1983 • 91 citations

Alternative Splicing of a Drosophila Tropomyosin Gene Generates Muscle Tropomyosin Isoforms with Different Carboxy-Terminal Ends

1984 • 91 citations

In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites.

1984 • 90 citations

Multiple discrete sites for premature RNA chain termination late in adenovirus-2 infection: enhancement by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.

1979 • 87 citations

Premature termination during adenovirus transcription

1979 • 87 citations

The E4 transcilpilonal unit of Ad2: far upstream sequences are required for its transactivation by E1A

1984 • 86 citations

A transcription enhancer acts in vitro over distances of hundreds of base-pairs on both circular and linear templates but not on chromatin-reconstituted DNA

1984 • 86 citations

Adenovirus 5 E2 transcription unit: an E1A-inducible promoter with an essential element that functions independently of position or orientation.

1984 • 86 citations

Sequence-Independent Autoregulation of the Adenovirus Type 5 E1A Transcription Unit

1985 • 86 citations

Specificity of the bacteriophage lambda N gene product (pN): Nut sequences are necessary and sufficient for antitermination by pN

1979 • 86 citations

Synthesis of a structural adenovirus polypeptide in the absence of viral DNA replication

1978 • 85 citations

Deletion mutants of adenovirus 2: Isolation and initial characterization of virus carrying mutations near the right end of the viral genome

1981 • 83 citations

Transactivation of plasmid-borne promoters by adenovirus and several herpes group viruses

1984 • 81 citations

DNA sequence analysis of the region encoding the terminal protein and the hypothetical N-gene product of adenovirus type 2.

1982 • 80 citations

In vitro transcription of adenovirus

1981 • 79 citations

Translational control of SV40 T antigen expressed from the adenovirus late promoter

1983 • 79 citations

Arrangement of messenger RNAs and protein coding sequences in the major late transcription unit of adenovirus 2

1980 • 76 citations

Nucleosome-like structural subunits of intranuclear parental adenovirus type 2 DNA

1979 • 76 citations

Multiple mRNA species with distinct 3′ termini are transcribed from the β2-microglobulin gene

1983 • 75 citations

Early Ad-2 transcription units: Only promoter-proximal RNA continues to be made in the presence of DRB

1979 • 75 citations

HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism.

1984 • 73 citations

Functions of purified E1A protein microinjected into mammalian cells.

1984 • 71 citations

T cells with receptors for IgD

1985 • 70 citations

Viral transcription in KB cells infected by temperature-sensitive "early" mutants of adenovirus type 5

1976 • 70 citations

Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products

1985 • 70 citations

Magic Enhancers?

1984 • 70 citations

Inhibition of adenovirus early region IV transcription in vitro by a purified viral DNA binding protein

1983 • 69 citations

Identification of adenovirus genes that require template replication for expression

1983 • 68 citations

The adenovirus-2 EIIa eariy gene promoter: sequences required for efficientin vitroandin vivotranscription

1983 • 68 citations

Accumulation of early and intermediate mRNA species during subgroup C adenovirus productive infections

1984 • 67 citations

Splice junctions in adenovirus 2 early region 4 mRNAs: multiple splice sites produce 18 to 24 RNAs

1984 • 67 citations

A Drosophila metabolic gene transcript is alternatively processed

1983 • 66 citations

RNA structures near poly(A) of adenovirus-2 late messenger RNAs

1978 • 66 citations

Cycloheximide stimulates early adenovirus transcription if early gene expression is allowed before treatment

1983 • 66 citations

Effect of adenovirus on metabolism of specific host mRNAs: transport control and specific translational discrimination.

1983 • 65 citations

DNA sequences from the adenovirus 2 genome.

1984 • 65 citations

Generation and functional analyses for base-substitution mutants of the adenovirus 2 major late promoter

1984 • 64 citations

Variation in the polyadenylylation site of bovine prolactin mRNA.

1982 • 63 citations

E1A 13S and 12S mRNA products made in Escherichia coli both function as nucleus-localized transcription activators but do not directly bind DNA.

1985 • 62 citations

Rapid intracellular turnover of adenovirus 5 early region 1A proteins

1984 • 62 citations

Role of intron-contained sequences in formation of moloney murine leukemia virus env mRNA.

1984 • 62 citations

Construction of an adenovirus-SV40 recombinant producing SV40 T antigen from an adenovirus late promoter

1981 • 61 citations

Premature termination by human RNA polymerase II occurs temporally in the adenovirus major late transcriptional unit.

1984 • 61 citations

Adenovirus chromatin structure at different stages of infection.

1981 • 60 citations

Two regions of the adenovirus 2 genome specify families of late polysomal RNAs containing common sequences.

1978 • 60 citations

The E1b promoter of Ad12 in mouse L tk- cells is activated by adenovirus region E1a.

1983 • 60 citations

Autoregulation of Adenovirus Type 5 Early Gene Expression II. Effect of Temperature-Sensitive Early Mutations on Virus RNA Accumulation

1978 • 59 citations

Adenovirus-infected, Cell-specific, DNA-binding Proteins

1974 • 59 citations

Characterization of adenovirus type 2 transcriptional complexes isolated from infected HeLa cell nuclei

1976 • 59 citations

Host range temperature-conditional mutants in the adenovirus DNA binding protein are defective in the assembly of infectious virus

1983 • 59 citations

Point mutation in the TATA box curtails expression of sea urchin H2A histone gene in vivo

1981 • 57 citations

Effects of Adenovirus Infection on rRNA Synthesis and Maturation in HeLa Cells

1983 • 56 citations

Two functions encoded by adenovirus early region 1A are responsible for the activation and repression of the DNA-binding protein gene.

1985 • 56 citations

Alternative splicing of a Drosophila tropomyosin gene generates muscle tropomyosin isoforms with different carboxy-terminal ends.

1984 • 56 citations

Organization of early region 1B of human adenovirus type 2: identification of four differentially spliced mRNAs

1985 • 56 citations

Increased MHC H–2K gene transcription in cultured mouse embryo cells after adenovirus infection

1985 • 56 citations

Visualization of the major late r strand transcription unit of adenovirus serotype 2

1981 • 55 citations

Transcription of adenovirus type 2 genes in a cell-free system: apparent heterogeneity of initiation at some promoters.

1981 • 55 citations

Sequence analysis of adenovirus DNA

1979 • 54 citations

Mapping the 5′ ends, 3′ ends, and splice sites of mRNAs from the early E3 transcription unit of adenovirus 5

1985 • 53 citations

Characterization of single-stranded viral DNA sequences present during replication of adenovirus types 2 and 5

1976 • 53 citations

The molecular structure of the 9 S mRNA from early region 1A of adenovirus serotype 2

1983 • 52 citations

Structural analysis of viral replicative intermediates isolated from adenovirus type 2-infected HeLa cell nuclei

1978 • 52 citations

The gene for the adenovirus 2 hexon polypeptide.

1984 • 52 citations

Analysis of the mouse dhfr promoter region: existence of a divergently transcribed gene.

1985 • 52 citations

Specific in vitro initiation of transcription on the adenovirus type 2 early and late EII transcription units.

1981 • 52 citations

Predicted structure of two adenovirus tumor antigens.

1980 • 51 citations

Adenovirus E3-early promoter: sequences required for activation by E1A

1985 • 51 citations

Enzymatic properties of viral replication complexes isolated from adenovirus type 2-infected HeLa cell nuclei

1977 • 50 citations

Analysis of the Expression of Genes Encoding Animal mRNA by in Vitro Techniques

1983 • 50 citations

Proximal and distal domains that control in vitro transcription of the adenovirus IVa2 gene.

1984 • 50 citations

Isolation and analysis of adenovirus type 5 mutants containing deletions in the gene encoding the DNA-binding protein

1985 • 49 citations

Vector Expression of Adenovirus Type 5 E1a Proteins: Evidence for E1a Autoregulation

1985 • 49 citations

Effect of protein synthesis inhibitors on viral mRNA's synthesized early in adenovirus type 2 infection

1978 • 49 citations

Control of cellular gene expression during adenovirus infection: induction and shut-off of dihydrofolate reductase gene expression by adenovirus type 2.

1983 • 48 citations

Transcription control region within the protein-coding portion of adenovirus E1A genes.

1984 • 48 citations

Localization of the 5′ terminus of late SV40 mRNA

1978 • 47 citations

Overproduction of the protein product of a nonselected foreign gene carried by an adenovirus vector.

1985 • 47 citations

Metabolism of mRNA from the Transforming Region of Adenovirus 2

1980 • 46 citations

DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2.

1982 • 46 citations

Intracellular forms of adenovirus DNA: integrated form of adenovirus DNA appears early in productive infection.

1976 • 46 citations

E1A control of gene expression is mediated by sequences 5' to the transcriptional starts of the early viral genes.

1983 • 46 citations

Control of adenovirus E1B mRNA synthesis by a shift in the activities of RNA splice sites.

1984 • 45 citations

Differential response of multiple ϵ-globin cap sites to cis- and trans-acting controls

1984 • 45 citations

Genes encoding the core proteins of adenovirus type 2.

1984 • 44 citations

Visualization of nascent RNA transcripts and simultaneous transcription and replication in viral nucleoprotein complexes from adenovirus 2-infected HeLa cells

1981 • 43 citations

Sequence-specific trans-activation of the adenovirus EIIa early promoter by the viral EIV transcription unit.

1985 • 42 citations

An adenovirus vector system used to express polyoma virus tumor antigens.

1985 • 42 citations

Virion core-like organization of intranuclear adenovirus chromatin late in infection

1980 • 42 citations

Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit

1983 • 42 citations

Regulation of transcription termination by the N gene protein of bacteriophage lambda

1981 • 41 citations

Isolation and structure of the gene for the progesterone-inducible protein uteroglobin.

1982 • 40 citations

Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAs

1983 • 39 citations

An adenovirus agnogene

1982 • 39 citations

The role of adenovirus early region 1A in the regulation of early regions 2A and 1B expression

1983 • 39 citations

Different exon-intron organization at the 5' part of a mouse class I gene is used to generate a novel H-2Kd-related mRNA.

1983 • 39 citations

Synthesis and processing of simian virus 40-specific RNA in adenovirus-infected, simian virus 40-transformed human cells

1983 • 39 citations

Structure of three spliced mRNAs from region E3 of adenovirus type 2

1983 • 38 citations

Growth-dependent expression of dihydrofolate reductase mRNA from modular cDNA genes.

1983 • 37 citations

Expression of adenoviral genetic information in productively infected cells

1982 • 36 citations

Regulation of integrated adenovirus sequences during adenovirus infection of transformed cells

1980 • 33 citations

Structure and function of adenovirus DNA binding protein: Comparison of the amino acid sequences of the Ad5 and Ad12 proteins derived from the nucleotide sequence of the corresponding genes

1983 • 33 citations

Effects of adenovirus infection on rRNA synthesis and maturation in HeLa cells.

1983 • 32 citations

The nucleotide sequence of mRNA for the Mr 19000 glycoprotein from early gene block III of adenovirus 2

1982 • 31 citations

Effect of adenovirus infection on expression of human histone genes.

1984 • 30 citations

The nucleotide sequence of the gene for protein IVa2 and of the 5' leader segment of the major late mRNAs of adenovirus type 5

1981 • 29 citations

Novel deletion mutants that enhance a distant upstream 5′ splice in the E3 transcription unit of adenovirus 2

1985 • 28 citations

The sequence of 3′-termini of mRNAs from early region III of adenovirus 2

1982 • 28 citations

Positive and negative control sequences within the distal domain of the adenovirus IVa2 promoter overlap with the major late promoter

1985 • 28 citations

Different mRNAs from the transforming region of highly oncogenic and non-oncogenic human adenoviruses

1982 • 27 citations

Comparison of the Nuclear Ribonucleoproteins Containing the Transcripts of Adenovirus‐2 and HeLa Cell DNA

1980 • 26 citations

Sequence-independent autoregulation of the adenovirus type 5 E1A transcription unit.

1985 • 26 citations

Adenovirus E1A protein activation of an integrated viral gene.

1984 • 25 citations

Splicing of the adenovirus-2 E1A 13S mRNA requires a minimal intron length and specific intron signals

1985 • 25 citations

Proteins encoded near the adenovirus late messenger RNA leader segments

1983 • 24 citations

Selective inhibition of adenovirus type 2 early region II and III transcription by an anisomycin block of protein synthesis.

1982 • 24 citations

Intranuclear site of replication of adenovirus DNA

1974 • 24 citations

Sequence arrangement and protein coding capacity of the adenovirus type 2 "i" leader

1983 • 24 citations

Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus.

1984 • 23 citations

Posttranscriptional control of DHFR gene expression during adenovirus 2 infection

1985 • 22 citations

In vitroaccurate initiation of transcription on the adenovirus type 2 IVa2 gene which does not contain a TATA box

1982 • 20 citations

Adenovirus DNA template for late transcription is not a replicative intermediate

1979 • 20 citations

Expression of the gene encoding the adenovirus DNA terminal protein precursor in productively infected and transformed cells

1982 • 19 citations

Cis and trans activation of adenovirus IVa₂gene transcription

1985 • 19 citations

Presence in infected cells of nonvirion proteins encoded by adenovirus messenger RNAs of the major late transcription regions L0 and L1

1985 • 19 citations

Preferential stimulation of transcription from simian virus 40 late and adeno IVa2 promoters in a HeLa cell extract.

1983 • 18 citations

Specific transcription of an adenoviral gene that possesses no TATA sequence homology in extracts of HeLa cells.

1984 • 17 citations

Plasmid-directed synthesis of genuine adenovirus 2 early-region 1A and 1B proteins in Escherichia coli.

1984 • 16 citations

Vector expression of adenovirus type 5 E1a proteins: evidence for E1a autoregulation.

1985 • 15 citations

Cellular transformation by adenoviruses

1984 • 14 citations

Coordinate regulation of two cytoplasmic RNA species transcribed from early region 2 of the adenovirus 2 genome

1981 • 13 citations

Splicing and the Regulation of Viral Gene Expression

1981 • 9 citations

Nuclear ribonucleoprotein particles from adenovirus infected Hela cells

1981 • 6 citations