Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit β-globin gene in mouse 3T6 cells

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTION

1979 • 2,730 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

The structure and evolution of the human β-globin gene family

1980 • 1,398 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

Restriction Endonucleases in the Analysis and Restructuring of DNA Molecules

1975 • 455 citations

A 200 base pair region at the 5$prime; end of the chicken adult $beta;-globin gene is accessible to nuclease digestion

1981 • 443 citations

A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs

1981 • 339 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.

1980 • 287 citations

Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene

1983 • 235 citations

DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus.

1981 • 231 citations

Rabbit β-globin mRNA production in mouse L cells transformed with cloned rabbit β-globin chromosomal DNA

1979 • 191 citations

Developmental Biology Using Purified Genes

1981 • 183 citations

Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.

1982 • 180 citations

Differences in human α-, β- and δ-globin gene expression in monkey kidney cells

1982 • 172 citations

Activation of globin genes during chicken development

1981 • 164 citations

Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene.

1982 • 119 citations

Sequence requirements for the transcription of the rabbit β-globin genein vivo: -80 region

1982 • 110 citations

beta-Thalassemia in a Kurdish Jew. Single base changes in the T-A-T-A box.

1982 • 106 citations

The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions

1982 • 103 citations

Isolation and characterization of temperature-sensitive mutants of Simian Virus 40

1972 • 96 citations

Deletion mapping a eukaryotic promoter.

1981 • 79 citations

Site-directed mutagenesis in DNA: Generation of point mutations in cloned β globin complementary DNA at the positions corresponding to amino acids 121 to 123

1978 • 78 citations

Transfer of human globin genes to erythroleukemic mouse cells.

1982 • 62 citations

Point mutation in the TATA box curtails expression of sea urchin H2A histone gene in vivo

1981 • 57 citations

A thermostable, sequence-specific restriction endonuclease from Bacillus stearothermophilus: BstPI

1979 • 16 citations

EXPRESSION OF β-GLOBIN GENES MODIFIED BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS

1981 • 11 citations

MODIFICATION OF THE RABBIT CHROMOSOMAL β-GLOBIN GENE BY RESTRUCTURING AND SITE-DIRECTED MUTAGENESIS

1981 • 10 citations