Transcription and RNA processing by the DNA tumour viruses

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

1977 • 1,301 citations

An amazing sequence arrangement at the 5′ ends of adenovirus 2 messenger RNA

1977 • 1,138 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

The Genome of Simian Virus 40

1978 • 948 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

The molecular biology of tumor viruses

1974 • 734 citations

Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

1979 • 678 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

Simian Virus 40 Deoxyribonucleic Acid Synthesis: the Viral Replicon

1972 • 609 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Ubiquitous, interspersed repeated sequences in mammalian genomes.

1980 • 568 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation.

1977 • 543 citations

The binding site on SV40 DNA for a T antigen-related protein

1978 • 542 citations

Biological Regulation and Development

1982 • 489 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Chromatin Structure: Deduced from a Minichromosome

1975 • 462 citations

Regulation of tumor antigen synthesis by simain virus 40 gene A

1975 • 435 citations

Viral DNA in transformed cells

1974 • 429 citations

Preparation of Native Chromatin and Damage Caused by Shearing

1975 • 413 citations

The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites

1978 • 409 citations

Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1979 • 395 citations

Coincidence of the promoter and capped 5′ terminus of RNA from the adenovirus 2 major late transcription unit

1978 • 390 citations

The genome of human papovavirus BKV

1979 • 378 citations

Heterogeneity and 5′-terminal structures of the late RNAs of simian virus 40

1978 • 372 citations

Construction and analysis of viable deletion mutants of simian virus 40

1976 • 355 citations

Overlapping genes in bacteriophage φX174

1976 • 345 citations

Studies on In Vitro Transformation by DNA and DNA Fragments of Human Adenoviruses and Simian Virus 40

1974 • 334 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

A map of cytoplasmic RNA transcripts from lytic adenovirus type 2, determined by electron microscopy of RNA:DNA hybrids

1977 • 303 citations

Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells

1978 • 284 citations

Two adenovirus mRNAs have a common 5′ terminal leader sequence encoded at least 10 kb upstream from their main coding regions

1977 • 283 citations

A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes

1979 • 278 citations

Autoregulation of simian virus 40 gene A by T antigen.

1976 • 248 citations

DNA-binding Proteins specific for Cells infected by Adenovirus

1973 • 247 citations

Use of Nondefective Adenovirus-Simian Virus 40 Hybrids for Mapping the Simian Virus 40 Genome

1973 • 243 citations

Location and identification of the genes for adenovirus type 2 early polypeptides

1976 • 239 citations

Organization and expression of early genes of simian virus 40

1978 • 238 citations

Inhibition of HeLa cell protein synthesis during adenovirus infection

1979 • 236 citations

Thermolabile DNA binding proteins from cells infected with a temperature-sensitive mutant of adenovrius defective in viral DNA synthesis

1975 • 231 citations

Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleases

1978 • 230 citations

A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2

1976 • 216 citations

The initiation sites for RNA transcription in Ad2 DNA

1977 • 208 citations

Characterization of t antigens in polyoma-infected and transformed cells

1978 • 208 citations

The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA

1980 • 204 citations

Simian virus 40 early mRNA's. I. Genomic localization of 3' and 5' termini and two major splices in mRNA from transformed and lytically infected cells

1979 • 199 citations

Organisation and sequence studies of the 17-piece chicken conalbumin gene

1979 • 199 citations

Biological activity of purified simian virus 40 T antigen proteins.

1978 • 197 citations

Mapping of Adenovirus 2 RNA Sequences in Lytically Infected Cells and Transformed Cell Lines

1974 • 195 citations

Mapping the spliced and unspliced late lytic SV40 RNAs

1978 • 193 citations

Enhancement of Adenovirus Growth in African Green Monkey Kidney Cell Cultures by SV40

1964 • 190 citations

Transcription of simian virus 40

1972 • 190 citations

Splicing as a requirement for biogenesis of functional 16S mRNA of simian virus 40.

1979 • 185 citations

Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome

1978 • 184 citations

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

1979 • 184 citations

Nucleotide sequence analysis of the leader segments in a cloned copy of adenovirus 2 fiber mRNA

1979 • 184 citations

The spliced structures of adenovirus 2 fiber message and the other late mRNAs

1978 • 184 citations

Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen.

1977 • 181 citations

Regulation of Early and Late Simian Virus 40 Transcription: Overproduction of Early Viral RNA in the Absence of a Functional T-Antigen

1977 • 176 citations

Transcription Units for mRNA Production in Eukaryotic Cells and Their DNA Viruses

1979 • 173 citations

Transformation with specific fragments of adenovirus DNAs I. Isolation of specific fragments with transforming activity of adenovirus 2 and 5 DNA

1977 • 170 citations

Mutations that allow human Ad2 and Ad5 to express late genes in monkey cells map in the viral gene encoding the 72K DNA binding protein

1979 • 170 citations

Novel mechanism for RNA maturation: the leader sequences of simian virus 40 mRNA are not transcribed adjacent to the coding sequences.

1977 • 169 citations

Characterization of the Autoregulation of Simian Virus 40 Gene A

1977 • 168 citations

Messenger rna for the ad2 dna binding protein: dna sequences encoding the first leader and heterogeneity at the mRNA 5′ end

1979 • 166 citations

T antigen binds to simian virus 40 DNA at the origin of replication.

1975 • 163 citations

Cell-free Synthesis of Adenovirus 2 Proteins Programmed by Fractionated Messenger RNA: A Comparison of Polypeptide Products and Messenger RNA Lengths

1974 • 163 citations

The nucleotide sequence and genome organization of the polyoma early region: Extensive nucleotide and amino acid homology with SV40

1979 • 162 citations

The nucleotide sequence of the transforming HpaI-E fragment of adenovirus type 5 DNA

1978 • 157 citations

Cell Transformation: A Study of Regulation with Types 5 and 12 Adenovirus Temperature-sensitive Mutants

1974 • 154 citations

New region of the simian virus 40 genome required for efficient viral transformation.

1978 • 153 citations

Hybridization maps of early and late messenger RNA sequences on the adenovirus type 2 genome

1976 • 151 citations

Comparison of viral RNA sequences in adenovirus 2-transformed and lytically infected cells

1975 • 147 citations

Viral DNA Synthesis in Cells Infected by Temperature-Sensitive Mutants of Simian Virus 40

1974 • 144 citations

Sequence from early region of polyoma virus DNA containing viral replication origin and encoding small, middle and (part of) large T antigens

1979 • 143 citations

The major late adenovirus type-2 transcription unit: Termination is downstream from the last poly(A) site

1979 • 141 citations

Tumor antigens induced by nontransforming mutants of polyoma virus

1978 • 141 citations

Transcription pattern of in vivo-labeled late simian virus 40 RNA: equimolar transcription beyond the mRNA 3' terminus

1978 • 140 citations

SV40 recombinants carrying rabbit β-globin gene coding sequences

1979 • 139 citations

Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus.

1977 • 139 citations

N-6-methyl-adenosine in adenovirus type 2 nuclear RNA is conserved in the formation of messenger RNA

1979 • 139 citations

The asymmetric segregation of parental nucleosomes during chromosome replication

1979 • 138 citations

DRB-induced premature termination of late adenovirus transcription

1978 • 136 citations

RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.

1979 • 136 citations

Transcription of the Adenovirus Genome by an α-Amanitine-Sensitive Ribonucleic Acid Polymerase in HeLa Cells

1972 • 134 citations

Genes for VA-RNA in adenovirus 2

1975 • 133 citations

Groups of adenovirus type 2 mRNA's derived from a large primary transcript: probable nuclear origin and possible common 3' ends

1978 • 132 citations

A map of simian virus 40 transcription sites expressed in productively infected cells

1973 • 130 citations

One predominant 5′-undecanucleotide in adenovirus 2 late messenger RNAs

1977 • 130 citations

The 5'-terminal leader sequence of late 16 S mRNA from cells infected with simian virus 40.

1978 • 128 citations

Loop structures in hybrids of early RNA and the separated strands of adenovirus DNA.

1977 • 126 citations

Possible role of the 72,000 dalton DNA-binding protein in regulation of adenovirus type 5 early gene expression

1978 • 124 citations

The definition of a large viral transcription unit late in Ad2 infection of HeLa cells: Mapping by effects of ultraviolet irradiation

1977 • 121 citations

Location of additional early gene sequences in the adenoviral chromosome

1979 • 115 citations

Mechanism for RNA splicing of gene transcripts

1979 • 114 citations

Relationship of Replication and Transcription of Simian Virus 40 DNA

1973 • 114 citations

Adenovirus transcription

1976 • 112 citations

Polyoma virus-specific 55K protein isolated from plasma membrane of productively infected cells is virus-codedand important for cell transformation

1979 • 112 citations

Block to multiplication of adenovirus serotype 2 in monkey cells

1975 • 111 citations

Mapping of Simian Virus 40 Early Functions on the Viral Chromosome

1973 • 109 citations

Virus-specific RNA in Cells Productively Infected or Transformed by Polyoma Virus

1974 • 108 citations

Further mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments

1977 • 107 citations

Studies of Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses V. Isolation of Additional Hybrids Which Differ in Their Simian Virus 40-Specific Biological Properties

1973 • 107 citations

Large and small tumor antigens from simian virus 40 have identical amino termini mapping at 0.65 map units.

1978 • 105 citations

Biochemical Consequences of Type 2 Adenovirus and Simian Virus 40 Double Infections of African Green Monkey Kidney Cells

1970 • 105 citations

Multiple 5′ terminal cap structures in late polyoma virus RNA

1979 • 105 citations

Organization of the Genomes of Polyoma Virus and SV40

1977 • 101 citations

Adenovirus-2 mRNA is transcribed as part of a high-molecular-weight precursor RNA.

1975 • 100 citations

Ultraviolet mapping of the adenovirus 2 early promoters

1977 • 100 citations

Mapping of RNA initiation sites by high doses of uv irradiation: Evidence for three independent promoters within the left 11% of the Ad-2 genome

1979 • 100 citations

State of Adenovirus 2 Deoxyribonucleic Acid in the Nucleus and Its Mode of Transcription: Studies with Isolated Viral Deoxyribonucleic Acid-Protein Complexes and Isolated Nuclei

1972 • 99 citations

Evidence for non-spliced SV40 RNA in undifferentiated murine teratocarcinoma stem cells

1979 • 98 citations

Incomplete splicing and deficient accumulation of the fiber messenger RNA in monkey cells infected by human adenovirus type 2

1980 • 95 citations

Effect of Cycloheximide on RNA Metabolism Early in Productive Infection with Adenovirus 2

1974 • 94 citations

Sequence analysis of adenovirus DNA: Complete nucleotide sequence of the spliced 5′ noncoding region of adenovirus 2 hexon messenger RNA

1979 • 93 citations

Transcription of the Polyoma Virus Genome: Synthesis and Cleavage of Giant Late Polyoma-Specific RNA

1971 • 91 citations

Simian Virus 40 Mutants with Deletions at the 3′ End of the Early Region Are Defective in Adenovirus Helper Function

1979 • 90 citations

Multiple discrete sites for premature RNA chain termination late in adenovirus-2 infection: enhancement by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.

1979 • 87 citations

Premature termination during adenovirus transcription

1979 • 87 citations

Structure of late adenovirus 2 heterogeneous nuclear RNA

1979 • 86 citations

Synthesis of a structural adenovirus polypeptide in the absence of viral DNA replication

1978 • 85 citations

Three species of polyoma virus tumor antigens share common peptides probably near the amino termini of the proteins

1978 • 84 citations

In vitro RNA-RNA splicing in adenovirus 2 mRNA formation.

1978 • 79 citations

Amplification in the leader sequence of late polyoma virus mRNAs

1979 • 78 citations

Mutational alterations within the simian virus 40 leader segment generate altered 16S and 19S mRNA's

1979 • 77 citations

Deletion mutants of simian virus 40 defective in biosynthesis of late viral mRNA.

1979 • 77 citations

Gaps and duplicated sequences in the leaders of SV40 16S RNA

1978 • 76 citations

The gene and messenger RNA for adenovirus polypeptide IX

1977 • 76 citations

Interaction of a Simian Papovavirus and Adenoviruses I. Induction of Adenovirus Tumor Antigen During Abortive Infection of Simian Cells

1966 • 76 citations

Topography of polyoma virus messenger RNA molecules

1976 • 75 citations

Early Ad-2 transcription units: Only promoter-proximal RNA continues to be made in the presence of DRB

1979 • 75 citations

Differentiation as a requirement for simian virus 40 gene expression in F-9 embryonal carcinoma cells.

1979 • 74 citations

Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species

1978 • 72 citations

Sequence arrangement of the 5' ends of simian virus 40 16S and 19S mRNAs.

1977 • 72 citations

Nucleotide sequence deletions within the coding region for small-t antigen of simian virus 40

1979 • 72 citations

Viral transcription in KB cells infected by temperature-sensitive "early" mutants of adenovirus type 5

1976 • 70 citations

Amino acid sequence homology between polyoma and SV40 tumour antigens deduced from nucleotide sequences

1978 • 68 citations

A supplementary adenoviral leader sequence and its role in messenger translation

1978 • 67 citations

Segments of simian virus 40 DNA spanning most of the leader sequence of the major late viral messenger RNA are dispensable.

1979 • 67 citations

Nuclear transcripts larger than the cytoplasmic mRNAs are specified by segments of the adenovirus genome coding for early functions

1976 • 67 citations

The nucleotide sequence of the transforming HindIII-G fragment of adenovirus type 5 DNA the region between map positions 4.5 (HpaI site) and 8.0 (HindIII site)

1979 • 66 citations

RNA structures near poly(A) of adenovirus-2 late messenger RNAs

1978 • 66 citations

Cell-free synthesis of simian virus 40 T-antigens

1978 • 66 citations

Overlapping of the VP2-VP3 gene and the VP1 gene in the SV40 genome

1977 • 65 citations

The low molecular weight of RNAs of adenovirus 2-infected cells

1978 • 65 citations

Nucleotide sequence analysis of viable deletion mutants lacking segments of the simian virus 40 genome coding for small t antigen

1979 • 64 citations

Studies of low molecular weight RNA from cells infected with adenovirus 2. I. The sequences at the 3' end of VA-RNA I.

1977 • 64 citations

Post-transcriptional restriction of human adenovirus expression in monkey cells

1975 • 61 citations

Nucleotide sequence at the junction between the coding region of the adenovirus 2 hexon messenger RNA and its leader sequence.

1978 • 60 citations

RNA synthesis in isolated nuclei: Identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and in vivo

1979 • 60 citations

Two regions of the adenovirus 2 genome specify families of late polysomal RNAs containing common sequences.

1978 • 60 citations

Autoregulation of Adenovirus Type 5 Early Gene Expression II. Effect of Temperature-Sensitive Early Mutations on Virus RNA Accumulation

1978 • 59 citations

Sequence heterogeneity at the 5' termini of late simian virus 40 19S and 16S mRNAs.

1979 • 59 citations

Interaction between the adenovirus DNA-binding protein and double-stranded DNA

1979 • 59 citations

Splicing patterns of nuclear precursors to the mRNA for adenovirus 2 DNA binding protein

1979 • 57 citations

DNA sequence alterations in Hr-t deletion mutants of polyoma virus

1979 • 56 citations

Polyoma virus has three late mRNA's: one for each virion protein

1978 • 56 citations

Nucleotide sequence and genetic organization of the polyoma late region: Features common to the polyoma early region and SV40

1979 • 54 citations

Sequence analysis of adenovirus DNA

1979 • 54 citations

Nucleotide sequence studies of polyoma DNA. The Hpa II 3/5 junction to the Hpa II 4/Hae III 18 junction, encoding the origin of DNA replication and the 5' end of the early region.

1978 • 51 citations

Heterogeneity of the 5' terminus of late mRNA induced by a viable simian virus 40 deletion mutant

1979 • 51 citations

Complementation of translational defect for growth of human adenovirus type 2 in simian cells by a simian virus 40-induced factor

1973 • 51 citations

Preparative isolation and mapping of adenovirus 2 early messenger RNA species

1976 • 49 citations

Analysis of polyoma virus nuclear RNA by mini-blot hybridization.

1977 • 49 citations

Effect of protein synthesis inhibitors on viral mRNA's synthesized early in adenovirus type 2 infection

1978 • 49 citations

Genetic Control Signals in DNA

1979 • 48 citations

Localization of the 5′ terminus of late SV40 mRNA

1978 • 47 citations

Purification and characterization of an early protein (E14K) from adenovirus type 2-infected cells

1978 • 47 citations

Autoregulation of Adenovirus Type 5 Early Gene Expression III. Transcription Studies in Isolated Nuclei

1979 • 45 citations

Common methionine-tryptic peptides near the amino-terminal end of primate papovavirus tumor antigens

1978 • 44 citations

Sequences from the genome of a non-transforming mutant of polyoma virus

1978 • 42 citations

Quantitative electron microscopy of early adenovirus RNA

1977 • 41 citations

Adenovirus Proteins and Their Messenger RNAs

1979 • 40 citations

Nucleotide sequence of the simian virus 40 small-t gene

1978 • 37 citations

The sequences between 0.59 and 0.54 map units on SV40 DNA code for the unique region of small t antigen

1978 • 36 citations

Inverted repeated DNA from Chinese hamster ovary cells studied with cloned DNA fragments.

1978 • 34 citations

Characterization of the 5'-terminal capped structures of late simian virus 40-specific mRNA

1978 • 34 citations

Characterization of early simian virus 40 transcriptional complexes: late transcription in the absence of detectable DNA replication.

1977 • 33 citations

Processing of late adenovirus nuclear RNA to mRNA

1979 • 32 citations

The genomic map position of the adenovirus type 2 glycoprotein

1979 • 32 citations

Adenovirus transcription. IV. Synthesis of viral-specific RNA in human cells infected with temperature-sensitive mutants of adenovirus 5

1976 • 32 citations

Capping structures of simian virus 40 19S and 16S mRNAs

1977 • 30 citations

Orientation of the Complementary Strands of Polyoma Virus DNA with Respect to the DNA Physical Map

1976 • 29 citations

A small RNA induced late in simian virus 40 infection can associate with early viral mRNAs.

1980 • 29 citations

Polyoma virus. The early region and its T-antigens

1979 • 28 citations

The transforming genes of SV40 and polyoma

1979 • 26 citations

Polyoma virus transcription early during productive infection of mouse 3T6 cells

1979 • 23 citations

Methylated 5′-terminal caps of adenovirus type 2 early mRNA: Evidence for at least six 5′-termini

1979 • 17 citations

Strand assignment of polyadenylated nuclear RNAs synthesized early in infection with adenovirus 2

1977 • 14 citations

Small RNAs and splicing

1980 • 11 citations

Transcription of a defective polyoma virus genome.

1978 • 5 citations