Vector Expression of Adenovirus Type 5 E1a Proteins: Evidence for E1a Autoregulation

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

1983 • 586 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA

1980 • 463 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Common Control of the Heat Shock Gene and Early Adenovirus Genes: Evidence for a Cellular E1A-like Activity

1984 • 331 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

Transcriptional activation and subsequent control of the human heat shock gene during adenovirus infection.

1983 • 295 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Size and location of the transforming region in human adenovirus type 5 DNA

1974 • 238 citations

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3′ coterminal mRNAs and five late families

1980 • 235 citations

E1a regions of the human adenoviruses and of the highly oncogenic simian adenovirus 7 are closely related

1985 • 213 citations

Non‐producer human cells induced by murine sarcoma virus

1975 • 204 citations

HeLa Cell β-Tubulin Gene Transcription Is Stimulated by Adenovirus 5 in Parallel with Viral Early Genes by an E1a-Dependent Mechanism

1984 • 187 citations

Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome

1978 • 184 citations

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

1979 • 184 citations

Eukaryotic viral vectors

1982 • 177 citations

E1A Control of Gene Expression Is Mediated by Sequences 5′ to the Transcriptional Starts of the Early Viral Genes

1983 • 169 citations

Functional Analysis of Adenovirus-5 Host-range Deletion Mutants Defective for Transformation of Rat Embryo Cells

1980 • 162 citations

Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes.

1984 • 150 citations

Dissection of overlapping functions within the adenovirus type 5 E1A gene.

1984 • 146 citations

Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level.

1984 • 138 citations

Transcriptional Activation and Subsequent Control of the Human Heat Shock Gene During Adenovirus Infection

1983 • 131 citations

An enhancer element is located 340 base pairs upstream from the adenovirus-2 E1A capsite

1983 • 116 citations

Adenovirus E1a Gene Product Expressed at High Levels in Escherichia coli Is Functional

1984 • 111 citations

Control of messenger RNA concentration by differential cytoplasmic half-life

1981 • 101 citations

Regulation of transcription of the adenovirus EII promoter by EIa gene products: absence of sequence specificity.

1984 • 94 citations

The E4 transcilpilonal unit of Ad2: far upstream sequences are required for its transactivation by E1A

1984 • 86 citations

HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism.

1984 • 73 citations

The adenovirus-2 EIIa eariy gene promoter: sequences required for efficientin vitroandin vivotranscription

1983 • 68 citations

RNA structures near poly(A) of adenovirus-2 late messenger RNAs

1978 • 66 citations

Adenovirus coded deoxyribonucleic acid binding protein. Isolation, physical properties, and effects of proteolytic digestion

1980 • 62 citations

Two functions encoded by adenovirus early region 1A are responsible for the activation and repression of the DNA-binding protein gene.

1985 • 56 citations

Regulation of Transcription of the Adenovirus EII Promoter by EIa Gene Products: Absence of Sequence Specificity

1984 • 50 citations

Transcription control region within the protein-coding portion of adenovirus E1A genes.

1984 • 48 citations

Comparison of the 34,000-Da pp60src substrate and a 38,000-Da phosphoprotein identified by monoclonal antibodies.

1983 • 42 citations

The role of adenovirus early region 1A in the regulation of early regions 2A and 1B expression

1983 • 39 citations

A paranuclear extract contains a unique set of viral transcripts late in SV40 infection

1981 • 25 citations

Replication of polyoma plasmid recombinants in mouse cells

1981 • 23 citations

Transcription Control Region Within the Protein-Coding Portion of Adenovirus E1A Genes

1984 • 17 citations

The Messenger RNAs from the Transforming Region of Human Adenoviruses

1983 • 14 citations