Sequence-Independent Autoregulation of the Adenovirus Type 5 E1A Transcription Unit

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

1977 • 2,233 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA

1980 • 463 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1979 • 395 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

cis and trans activation of globin gene transcription in transient assays.

1983 • 257 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Isolation of deletion and substitution mutants of adenovirus type 5

1978 • 230 citations

HeLa Cell β-Tubulin Gene Transcription Is Stimulated by Adenovirus 5 in Parallel with Viral Early Genes by an E1a-Dependent Mechanism

1984 • 187 citations

Regulation of the Primary Expression of the Early Adenovirus Transcription Units

1979 • 184 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

Cloning of a DNA fragment from the left-hand terminus of the adenovirus type 2 genome and its use in site-directed mutagenesis

1981 • 157 citations

Activation of early adenovirus transcription by the herpesvirus immediate early gene: evidence for a common cellular control factor.

1982 • 148 citations

Dissection of overlapping functions within the adenovirus type 5 E1A gene.

1984 • 146 citations

Adenovirus EIIA early promoter: transcriptional control elements and induction by the viral pre-early EIA gene, which appears to be sequence independent.

1985 • 140 citations

An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.

1985 • 131 citations

Characterization of cells transformed by Ad5/Ad12 hybrid early region I plasmids

1982 • 118 citations

The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions

1982 • 103 citations

Control of messenger RNA concentration by differential cytoplasmic half-life

1981 • 101 citations

Regulation of transcription of the adenovirus EII promoter by EIa gene products: absence of sequence specificity.

1984 • 94 citations

The E4 transcilpilonal unit of Ad2: far upstream sequences are required for its transactivation by E1A

1984 • 86 citations

Differential activation of RNA polymerase III-transcribed genes by the polyomavirus enhancer and the adenovirus E1A gene products

1985 • 81 citations

Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products

1985 • 70 citations

The adenovirus-2 EIIa eariy gene promoter: sequences required for efficientin vitroandin vivotranscription

1983 • 68 citations

Identification of families of overlapping polypeptides coded by early “transforming” gene region 1 of human adenovirus type 2

1979 • 64 citations

The E1b promoter of Ad12 in mouse L tk- cells is activated by adenovirus region E1a.

1983 • 60 citations

Characterization of human adenovirus type 5 early region 1A polypeptides using antitumor sera and an antiserum specific for the carboxy terminus

1983 • 54 citations

Regulation of Transcription of the Adenovirus EII Promoter by EIa Gene Products: Absence of Sequence Specificity

1984 • 50 citations

Transcription control region within the protein-coding portion of adenovirus E1A genes.

1984 • 48 citations

Adenovirus gene expression: Control at multiple steps of mRNA biogenesis

1982 • 43 citations

Far upstream sequences are required for efficient transcription from the adenovirus-2 E1A transcription unit

1983 • 42 citations

Functional analysis of the nucleotide sequence surrounding the cap site for adenovirus type 5 region E1A messenger RNAs

1983 • 39 citations

Peptide maps and N-terminal sequences of polypeptides from early region 1A of human adenovirus 5

1984 • 31 citations