cis and trans activation of globin gene transcription in transient assays.

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

Immunoglobulin gene transcription is activated by downstream sequence elements

1983 • 830 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Enhancer elements

1983 • 576 citations

Simian virus 40 tandem repeated sequences as an element of the early promoter.

1981 • 462 citations

Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product

1982 • 454 citations

A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

1980 • 429 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing

1982 • 372 citations

A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs

1981 • 339 citations

Deletion mapping of DNA regions required for SV40 early region promoter function in vivo.

1982 • 328 citations

The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements

1983 • 299 citations

β+ Thalassemia: Aberrant splicing results from a single point mutation in an intron

1981 • 235 citations

Purification of genomic sequences from bacteriophage libraries by recombination and selectionin vivo

1983 • 221 citations

Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.

1982 • 180 citations

Differences in human α-, β- and δ-globin gene expression in monkey kidney cells

1982 • 172 citations

Activation of early adenovirus transcription by the herpesvirus immediate early gene: evidence for a common cellular control factor.

1982 • 148 citations

Analysis of the Transcriptional Enhancer Effect

1983 • 82 citations

Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region.

1982 • 71 citations

Correct transcription of a cloned mouse immunoglobulin gene in vivo.

1983 • 71 citations

Expression of unselected adenovirus genes in human cells co-transformed with the HSV-1 tk gene and adenovirus 2 DNA

1980 • 66 citations

Isolation and Characterization of Human DNA Fragments with Nucleotide Sequence Homologies with the Simian Virus 40 Regulatory Region

1982 • 28 citations