The Use ofXenopusOocytes for the Study of Ion Channel

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Multiple receptors for dopamine

1979 • 3,739 citations

Three types of neuronal calcium channel with different calcium agonist sensitivity

1985 • 2,212 citations

Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals

1972 • 1,861 citations

G proteins and dual control of adenylate cyclase

1984 • 1,811 citations

The role of hormone receptors and GTP-regulatory proteins in membrane transduction

1980 • 1,750 citations

Functional messenger RNAs are produced by SP6in vitrotranscription of cloned cDNAs

1984 • 1,533 citations

The influence of potassium and chloride ions on the membrane potential of single muscle fibres

1959 • 1,458 citations

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

1984 • 1,339 citations

Co‐operative action of calcium ions in transmitter release at the neuromuscular junction

1967 • 1,326 citations

Junctional intercellular communication: the cell-to-cell membrane channel.

1981 • 1,268 citations

Calcium channel modulation by neurotransmitters, enzymes and drugs

1983 • 1,267 citations

The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart

1987 • 1,186 citations

Calcium Channel

1981 • 1,184 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Current topics in developmental biology

1998 • 1,090 citations

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

1986 • 979 citations

Phosphorylated Proteins as Physiological Effectors

1978 • 975 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Existence of distinct sodium channel messenger RNAs in rat brain

1986 • 909 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

GTP-binding proteins couple cardiac muscarinic receptors to a K channel

1985 • 868 citations

Mechanism of ion permeation through calcium channels

1984 • 850 citations

Cell membrane receptors for drugs and hormones: A multidisciplinary approach

1979 • 850 citations

Use of Frog Eggs and Oocytes for the Study of Messenger RNA and its Translation in Living Cells

1971 • 774 citations

A novel type of cardiac calcium channel in ventricular cells

1985 • 745 citations

Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

1985 • 732 citations

Calcium Channels in Excitable Cell Membranes

1983 • 725 citations

Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.

1985 • 715 citations

Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters†

1976 • 694 citations

Inward current channels activated by intracellular Ca in cultured cardiac cells

1981 • 687 citations

Oocyte Maturation

1979 • 662 citations

Serotonin and cyclic AMP close single K+ channels in Aplysia sensory neurones

1982 • 658 citations

Non‐selective conductance in calcium channels of frog muscle: calcium selectivity in a single‐file pore.

1984 • 643 citations

Two Distinct Central Serotonin Receptors with Different Physiological Functions

1981 • 640 citations

A transient calcium‐dependent chloride current in the immature Xenopus oocyte.

1983 • 627 citations

A quantitative description of end‐plate currents

1972 • 625 citations

Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase

1984 • 567 citations

The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity

1984 • 539 citations

Expression of functional sodium channels from cloned cDNA

1986 • 537 citations

Patch clamp measurements onXenopus laevis oocytes: currents through endogenous channels and implanted acetylcholine receptor and sodium channels

1986 • 534 citations

Uncoupling of cardiac muscarinic and β-adrenergic receptors from ion channels by a guanine nucleotide analogue

1985 • 527 citations

COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS*

1967 • 517 citations

AN ULTRASENSITIVE VIBRATING PROBE FOR MEASURING STEADY EXTRACELLULAR CURRENTS

1974 • 514 citations

Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.

1984 • 513 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

Human β-globin pre-mRNA synthesized in vitro is accurately spliced in xenopus oocyte nuclei

1983 • 500 citations

Enhancement of calcium current in Aplysia neurones by phorbol ester and protein kinase C

1985 • 476 citations

Cholinergic and catecholaminergic receptors in the Xenopus oocyte membrane

1982 • 475 citations

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors

1983 • 473 citations

A calcium-dependent transient outward current in Xenopus laevis oocytes

1982 • 473 citations

Fast block to polyspermy in sea urchin eggs is electrically mediated

1976 • 456 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

The effect of voltage on the time course of end‐plate currents

1972 • 443 citations

An introduction to embryology

1965 • 429 citations

5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown.

1985 • 429 citations

Decrease of gap junction permeability induced by dopamine and cyclic adenosine 3':5'-monophosphate in horizontal cells of turtle retina

1984 • 429 citations

Progesterone-stimulated meiotic cell division in Xenopus oocytes. Induction by regulatory subunit and inhibition by catalytic subunit of adenosine 3':5'-monophosphate-dependent protein kinase.

1977 • 419 citations

Two types of calcium channels in the somatic membrane of new‐born rat dorsal root ganglion neurones.

1985 • 412 citations

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Properties and function of the purified protein.

1984 • 411 citations

Identification of the alpha subunit half-cystine specifically labeled by an affinity reagent for the acetylcholine receptor binding site.

1984 • 408 citations

Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABA

1983 • 402 citations

Inactivation of Ca conductance dependent on entry of Ca ions in molluscan neurons.

1979 • 397 citations

Chloride current induced by injection of calcium into Xenopus oocytes.

1984 • 395 citations

Voltage‐activated and calcium‐activated currents studied in solitary rod inner segments from the salamander retina

1982 • 394 citations

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

1985 • 390 citations

The control of gene expression in animal development

1974 • 369 citations

Expression of functional acetylcholine receptor from cloned cDNAs

1984 • 366 citations

Protein kinase C regulates ionic conductance in hippocampal pyramidal neurons: electrophysiological effects of phorbol esters.

1985 • 361 citations

Three types of calcium‐dependent channel in rat lacrimal glands.

1984 • 359 citations

Phosphorylation of Ion channels

1985 • 348 citations

The inhibitory guanine nucleotide-binding regulatory component of adenylate cyclase. Subunit dissociation and guanine nucleotide-dependent hormonal inhibition.

1984 • 345 citations

RAS proteins can induce meiosis in xenopus oocytes

1985 • 341 citations

Opposite effects of cyclic GMP and cyclic AMP on Ca2+ current in single heart cells

1986 • 338 citations

An elevated free cytosolic Ca2+ wave follows fertilization in eggs of the frog, Xenopus laevis.

1985 • 336 citations

Cyclic Nucleotide-dependent Protein Kinases

1970 • 334 citations

Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels

1984 • 334 citations

Two Distinct Populations of Calcium Channels in a Clonal Line of Pituitary Cells

1985 • 323 citations

Inositol 1,4,5-trisphosphate microinjection activates sea urchin eggs

1984 • 316 citations

Kinase C activator 1,2-oleoylacetylglycerol attenuates voltage-dependent calcium current in sensory neurons.

1986 • 313 citations

Dopamine decreases conductance of the electrical junctions between cultured retinal horizontal cells.

1985 • 299 citations

The control of gene expression in animal development

1974 • 292 citations

Relative roles of the pituitary, follicle cells, and progesterone in the induction of oocyte maturation in Rana pipiens

1967 • 291 citations

Protein kinase C activation induces conductance changes in Hermissenda photoreceptors like those seen in associative learning

1986 • 289 citations

[25] The use of xenopus oocytes for the expression of cloned genes

1983 • 285 citations

Electrical Properties of Egg Cell Membranes

1979 • 277 citations

Role of acetylcholine receptor subunits in gating of the channel

1985 • 272 citations

Inactivation of calcium channel current in the calf cardiac Purkinje fiber. Evidence for voltage- and calcium-mediated mechanisms.

1984 • 272 citations

ADVANCES IN BEHAVIORAL BIOLOGY

1972 • 271 citations

Steroid-induced meiotic division in Xenopus laevis oocytes: surface and calcium

1978 • 268 citations

Cyclic AMP-dependent protein kinase closes the serotonin-sensitive K+channels of Aplysia sensory neurones in cell-free membrane patches

1985 • 265 citations

A structural model of the acetylcholine receptor channel based on partition energy and helix packing calculations

1984 • 260 citations

Activation of frog (Xenopus laevis) eggs by inositol trisphosphate. I. Characterization of Ca2+ release from intracellular stores.

1985 • 255 citations

Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport.

1985 • 254 citations

Permeability of a cell junction and the local cytoplasmic free ionized calcium concentration: A study with aequorin

1976 • 254 citations

Inositol 1,4,5-trisphosphate mimics muscarinic response in Xenopus oocytes

1985 • 249 citations

Modulation of single Ca2+-dependent K+-channel activity by protein phosphorylation

1985 • 249 citations

A Model for the Tertiary Structure of p21, the Product of the ras Oncogene

1985 • 248 citations

Molecular mechanisms involved in α-adrenergic responses

1981 • 246 citations

Calcium currents in internally perfused nerve cell bodies of Limnea stagnalis

1982 • 246 citations

Reversal of current through calcium channels in dialysed single heart cells

1982 • 241 citations

Stimulus-permeability coupling: role of calcium in the receptor regulation of membrane permeability.

1978 • 239 citations

Currents carried by monovalent cations through calcium channels in mouse neoplastic B lymphocytes.

1985 • 239 citations

Single voltage-dependent chloride-selective channels of large conductance in cultured rat muscle

1983 • 229 citations

Regulation of adenylate cyclase by adenosine

1979 • 218 citations

Progesterone inhibits membrane-bound adenylate cyclase in Xenopus laevis oocytes

1981 • 218 citations

The effects of caffeine on the noradrenaline‐sensitive calcium store in rabbit aorta.

1984 • 217 citations

Progesterone inhibits adenylate cyclase in Xenopus oocytes. Action on the guanine nucleotide regulatory protein.

1981 • 217 citations

Translation of exogenous messenger RNA coding for nicotinic acetylcholine receptors produces functional receptors in Xenopus oocytes

1982 • 217 citations

Messenger RNA coding for only the alpha subunit of the rat brain Na channel is sufficient for expression of functional channels in Xenopus oocytes.

1986 • 214 citations

Early effect of progesterone on levels of cyclic adenosine 3‘:5‘-monophosphate in Xenopus oocytes.

1979 • 213 citations

Fertilization increases the polyphosphoinositide content of sea urchin eggs

1984 • 209 citations

Regulation of cortical vesicle exocytosis in sea urchin eggs by inositol 1,4,5-trisphosphate and GTP-binding protein.

1986 • 209 citations

Secretory functions of egg cortical granules in fertilization and development: A critical review

1978 • 209 citations

Serotonin-stimulated phosphoinositide turnover: mediation by the S2 binding site in rat cerebral cortex but not in subcortical regions.

1985 • 197 citations

Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells.

1985 • 197 citations

Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes

1981 • 197 citations

Acetylcholine receptors in the oocyte membrane

1977 • 194 citations

Messenger RNA from human brain induces drug- and voltage-operated channels in Xenopus oocytes

1984 • 192 citations

The character of the muscarinic receptors in different regions of the rat brain

1980 • 188 citations

Properties and regulation of guanylate cyclase and some proposed functions for cyclic GMP.

1979 • 187 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

High selectivity of calcium channels in single dialysed heart cells of the guinea‐pig.

1984 • 186 citations

A fast block to polyspermy in frogs mediated by changes in the membrane potential

1980 • 182 citations

Rabbit haemoglobin synthesis in frog cells: the translation of reticulocyte 9 s RNA in frog oocytes

1971 • 181 citations

Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices

1984 • 180 citations

Kinetic studies of calcium release from sarcoplasmic reticulum in vitro.

1983 • 178 citations

Tumor promoter phorbol myristate acetate inhibits Ca2+ influx through voltage-gated Ca2+ channels in two secretory cell lines, PC12 and RINm5F.

1986 • 178 citations

Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

1985 • 175 citations

Expression and Modulation of Voltage-Gated Calcium Channels After RNA Injection in Xenopus Oocytes

1986 • 174 citations

Single-channel recordings of apical membrane chloride conductance in A6 epithelial cells

1984 • 174 citations

Cyclic Nucleotide-dependent Protein Kinases

1971 • 171 citations

Cloning, sequencing and expression of cDNA for a novel subunit of acetylcholine receptor from calf muscle

1985 • 169 citations

Progesterone induces a rapid increase in [Ca2+]in of Xenopus laevis oocytes.

1980 • 169 citations

A Ca-dependent Cl− conductance in cultured mouse spinal neurones

1984 • 165 citations

Bimodal regulation of adenylate cyclase

1982 • 161 citations

A large anion-selective channel has seven conductance levels

1986 • 161 citations

Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.

1984 • 158 citations

Voltage-dependence of drug-induced conductance in frog neuromuscular junction.

1975 • 156 citations

Guanosine 5'-O-thiotriphosphate stimulates phospholipase C activity in plasma membranes of rat hepatocytes.

1985 • 154 citations

Neurotransmitter receptors mediate cyclic GMP formation by involvement of arachidonic acid and lipoxygenase.

1984 • 154 citations

Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'‐cyclic monophosphate.

1984 • 153 citations

Ion Channels in Cardiac Cell Membranes

1984 • 148 citations

Electrical properties and fine structure of the ampullary canals of Lorenzini.

1966 • 144 citations

An electrical block is required to prevent polyspermy in eggs fertilized by natural mating of Xenopus laevis

1982 • 144 citations

Free calcium in Xenopus embryos measured with ion-selective microelectrodes

1980 • 142 citations

Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.

1985 • 140 citations

Electrical currents through full-grown and maturing Xenopus oocytes.

1979 • 138 citations

Identification and properties of cyclic nucleotide phosphodiesterases

1982 • 135 citations

Bidirectional control of cytosolic free calcium by thyrotropin-releasing hormone in pituitary cells

1985 • 135 citations

Expression of functional GABA, glycine and glutamate receptors in Xenopus oocytes injected with rat brain mRNA

1984 • 134 citations

Voltage-dependent kinetics of an anionic channel of large unit conductance in macrophages and myotube membranes

1984 • 133 citations

Muscarinic cholinergic receptor-mediated activation of phosphodiesterase.

1982 • 133 citations

Oogenesis in Xenopus laevis (Daudin). V. Relationships between developing oocytes and their investing follicular tissues

1978 • 132 citations

Cyclic nucleotide fluctuations during steroid induced meiotic maturation of frog oocytes

1977 • 131 citations

Free calcium changes associated with hormone action in amphibian oocytes

1980 • 131 citations

High conductance anion-selective channels in rat cultured Schwann cells

1984 • 128 citations

Membrane junctions in xenopus eggs: their distribution suggests a role in calcium regulation

1983 • 124 citations

Role of calcium mobilization in mediation of acetylcholine‐evoked chloride currents in Xenopus laevis oocytes.

1985 • 124 citations

Oocyte-Follicle Cell Gap Junctions in Xenopus laevis and the Effects of Gonadotropin on Their Permeability

1979 • 122 citations

Site of sperm entry and a cortical contraction associated with egg activation in the frog Rana pipens

1975 • 122 citations

Chapter 4 Origin and Establishment of Embryonic Polar Axes in Amphibian Development

1977 • 120 citations

Phospholipid-sensitive Ca2+-dependent protein kinase: a major protein phosphorylation system

1984 • 120 citations

The onset of activation responsiveness during maturation coincides with the formation of the cortical endoplasmic reticulum in oocytes of Xenopus laevis

1984 • 119 citations

Nature of the receptor‐regulated calcium pool in the rat parotid gland.

1982 • 119 citations

Fast polyspermy block and activation potential

1979 • 118 citations

Are there purinergic receptors on parotid acinar cells?

1982 • 118 citations

Serotonin receptors induced by exogenous messenger RNA in Xenopus oocytes

1983 • 118 citations

Identification of a voltage-dependent anion channel in the apical membrane of a Cl?-secretory epithelium (MDCK)

1985 • 118 citations

Calcium‐dependent polyphosphoinositide hydrolysis is associated with exocytosis in vitro

1985 • 116 citations

Involvement of a GTP-binding protein in mediation of serotonin and acetylcholine responses in Xenopus oocytes injected with rat brain messenger RNA

1986 • 116 citations

Electrical Characteristics and Activation Potential of Bufo Eggs

1959 • 115 citations

Neurotransmitter Receptor Interactions

1972 • 115 citations

Serotonin increases an anomalously rectifying K+ current in the Aplysia neuron R15.

1983 • 114 citations

The Biosynthesis of Biologically Active Proteins in mRNA-MicroinjectedXenopusOocyte

1985 • 111 citations

Sodium channels induced by depolarization of the Xenopus laevis oocyte.

1982 • 111 citations

Glutamate and kainate receptors induced by rat brain messenger RNA in Xenopus oocytes

1984 • 110 citations

Characterization of a chloride conductance activated by hyperpolarization in Aplysia neurones.

1983 • 109 citations

Single-channel properties of the reconstituted voltage-regulated Na channel isolated from the electroplax of Electrophorus electricus.

1984 • 109 citations

Initiation of the activation potential by an increase in intracellular calcium in eggs of the frog, Rana pipiens

1981 • 107 citations

Sequence organization of the poly(A) RNA synthesized and accumulated in lampbrush chromosome stage Xenopus laevis oocytes

1982 • 106 citations

pH changes associated with meiotic maturation in oocytes of Xenopus laevis

1981 • 103 citations

The frog; its reproduction and development

1951 • 100 citations

Properties of acetylcholine receptors translated by cat muscle mRNA in Xenopus oocytes.

1982 • 100 citations

Inhibition of rabbit intestine mediated by α‐ and β‐adrenoceptors

1970 • 100 citations

Inhibition of oocyte maturation by theophylline: Possible mechanism of action

1976 • 98 citations

The Ultrastructure of the Cytoplasm of the Developing Amphibian Egg

1966 • 98 citations

Mouse-Torpedo hybrid acetylcholine receptors: functional homology does not equal sequence homology.

1985 • 98 citations

Partial purification and functional expression of brain mRNAs coding for neurotransmitter receptors and voltage-operated channels.

1984 • 97 citations

High affinity binding of alpha-bungarotoxin to the purified alpha-subunit and to its 27,000-dalton proteolytic peptide from Torpedo marmorata acetylcholine receptor. Requirement for sodium dodecyl sulfate.

1983 • 97 citations

The modifications of cortical endoplasmic reticulum during in vitro maturation of Xenopus laevis oocytes and its involvement in cortical granule exocytosis

1984 • 97 citations

Obligatory separation of hormone binding and biological response curves in systems dependent upon secondary mediators of hormone action.

1981 • 96 citations

The mechanism for increased protein synthesis during Xenopus oocyte maturation

1982 • 96 citations

Voltage-operated channels induced by foreign messenger RNA in Xenopus oocytes

1983 • 95 citations

Calcium, potassium, and sodium exchange by full-grown and maturing Xenopus laevis oocytes

1977 • 93 citations

Drosophila mutants reveal two components of fast outward current

1983 • 92 citations

Rat brain 5-HT1C receptors are encoded by a 5-6 kbase mRNA size class and are functionally expressed in injected Xenopus oocytes

1987 • 91 citations

The involvement of inositol 1,4,5‐trisphosphate and calcium in the two‐component response to acetylcholine in Xenopus oocytes.

1987 • 90 citations

A transient inward current elicited by hyperpolarization during serotonin activation in Xenopus oocytes

1985 • 89 citations

Synthesis of chick brain GABA receptors by frog oocytes

1982 • 89 citations

Fluctuation analysis of neutral amino acid responses in cultured mouse spinal neurones.

1982 • 87 citations

Cyclic AMP-mediated control of meiosis: effects of progesterone, cholera toxin, and membrane-active drugs in Xenopus laevis oocytes.

1982 • 87 citations

Adenosine-induced slow ionic currents in the Xenopus oocyte

1982 • 87 citations

Characterization of neurotransmitter receptor-mediated phosphatidylinositol hydrolysis in the rat hippocampus

1984 • 86 citations

Neurotransmitter-receptor interactions

1971 • 86 citations

Relaxation measurements on the acetylcholine receptor.

1975 • 85 citations

Maturation of Xenopus oocytes

1977 • 85 citations

Fertilization potential and electrical properties of the Xenopus laevis egg

1985 • 85 citations

The wave of activation current in the Xenopus egg

1985 • 83 citations

Properties and oxidative regulation of guanylate cyclase.

1977 • 83 citations

Pertussis toxin inhibits chemotactic factor‐induced phospholipase C stimulation and lysosomal enzyme secretion in rabbit neutrophils

1985 • 81 citations

Transient localizations of messenger RNA in Xenopus laevis oocytes

1982 • 81 citations

Fertilization of amphibian eggs: A comparison of electrical responses between anurans and urodeles

1983 • 79 citations

Cyclic AMP levels during the maturation of Xenopus oocytes

1985 • 78 citations

Voltage sensitive, high-conductance chloride channels in the luminal membrane of cultured pulmonary alveolar (type II) cells

1985 • 78 citations

An Introduction to Embryology

1961 • 78 citations

Calmodulin triggers the resumption of meiosis in amphibian oocytes.

1981 • 77 citations

Serotonin and cyclic GMP both induce an increase of the calcium current in the same identified molluscan neurons

1986 • 75 citations

Types of muscarinic response in oocytes

1980 • 75 citations

Progesterone inhibition of Xenopus oocyte adenylate cyclase is not mediated via the Bordetella pertussis toxin substrate.

1984 • 75 citations

DRUGS AFFECTING THE PERIPHERAL NERVOUS SYSTEM

1968 • 75 citations

Studies of the voltage-dependent polyspermy block using cross-species fertilization of amphibians

1983 • 73 citations

Lateral mobility of plasma membrane lipids in Xenopus eggs: Regional differences related to animal/vegetal polarity become extreme upon fertilization

1984 • 73 citations

Electrical membrane properties of the Xenopus laevis oocyte during progesterone-induced meiotic maturation

1981 • 71 citations

Regulation of the amphibian oocyte plasma membrane ion permeability by cytoplasmic factors during the first meiotic division

1977 • 71 citations

Calmodulin — And its role in cellular activation

1981 • 71 citations

Electrical responses of immature and mature Rana pipiens oocytes to sperm and other activating stimuli

1981 • 68 citations

Acetylcholine and phorbol esters inhibit potassium currents evoked by adenosine and cAMP in Xenopus oocytes.

1985 • 68 citations

Interspersed poly(A) RNAs of amphibian oocytes are not translatable

1984 • 68 citations

Fertilization‐induced ionic conductances in eggs of the frog, Rana pipiens.

1985 • 68 citations

Kinetics of agonist conductance changes during hyperpolarization at frog endplates

1997 • 67 citations

The activities and concentrations of sodium and potassium in toad oocytes

1969 • 67 citations

The Amphibian Egg Cortex in Fertilization and Early Development

1980 • 67 citations

Islet activating protein inhibits physiological responses evoked by cardiac muscarinic acetylcholine receptors. Role of guanosine triphosphate binding proteins in regulation of potassium permeability

1985 • 66 citations

Properties of human brain glycine receptors expressed in Xenopus oocytes

1984 • 64 citations

<b>SYNTHESIS OF CAT MUSCLE ACETYLCHOLINE RECEPTORS BY <i>XENOPUS </i></b><b>OOCYTES </b>

1982 • 64 citations

Antibodies specific for amino acid 12 of the ras oncogene product inhibit GTP binding.

1985 • 63 citations

Calcium and the action of adrenaline, adenosine triphosphate and carbachol on guinea‐pig taenia caeci

1982 • 63 citations

Diacylglycerol downregulates junctional membrane permeability. TMB-8 blocks this effect

1985 • 63 citations

FORSKOLIN INCREASES cAMP AND INHIBITS PROGESTERONE INDUCED MEIOSIS REINITIATION IN XENOPUS LAEVIS OOCYTES

1982 • 59 citations

Reference Phase Analysis of Free and Bound Intracellular Solutes

1979 • 58 citations

Oocyte adenylyl cyclase contains N_i, yet the guanine nucleotide‐dependent inhibition by progesterone is not sensitive to pertussis toxin

1984 • 57 citations

The ionic components of the current pulses generated by developing fucoid eggs

1976 • 57 citations

KINETICS OF AGONIST CONDUCTANCE CHANGES DURING HYPERPOLARIZATION AT FROG ENDPLATES

1975 • 56 citations

A Cl− conductance activated by hyperpolarization in Aplysia neurones

1982 • 56 citations

Synthesis of functional chick brain GABA-benzodiazepine-barbiturate/receptor complexes in mRNA-injected Xenopus oocytes

1983 • 56 citations

Calmodulin

1981 • 55 citations

Activity coefficients of intracellular Na+ and K+ during development of frog oocytes

1978 • 55 citations

A Ca2+-activated channel from Xenopus laevis oocyte membranes reconstituted into planar bilayers.

1984 • 54 citations

In GH3 pituitary cells, acetylcholine and vasoactive intestinal peptide antagonistically modulate adenylate cyclase, cyclic AMP content, and prolactin secretion.

1983 • 54 citations

Receptor-stimulated phosphoinositide metabolism: a role for GTP-binding proteins?

1985 • 53 citations

Intracellular Ca2+-dependent and Ca2+-independent responses of rat brain serotonin receptors transplanted to Xenopus oocytes

1985 • 52 citations

Progesterone-induced down-regulation of an electrogenic Na+, K+-ATPase during the first meiotic division in amphibian oocytes

1982 • 52 citations

Two calcium currents in Neanthes arenaceodentatus egg cell membranes.

1984 • 52 citations

Role of Cyclic Nucleotides in Excitable Cells

1980 • 51 citations

Spontaneous action potentials produced by Na and Cl channels in maturing Rana pipiens oocytes

1983 • 50 citations

Intercellular junctions between the follicle cells and oocytes of Xenopus laevis

1984 • 50 citations

Cyclic Nucleotides, Protein Phosphorylation and Synaptic Function

1976 • 49 citations

Induction and disappearance of excitability in the oocyte of Xenopus laevis: a voltage‐clamp study.

1984 • 48 citations

Reference phase analysis of free and bound intracellular solutes. I. Sodium and potassium in amphibian oocytes

1979 • 48 citations

Acetylcholine promotes progesterone‐induced maturation of Xenopus oocytes

1984 • 48 citations

Translation and functional expression of cell-cell channel mRNA inXenopus oocytes

1985 • 47 citations

Recording of single γ-aminobutyrate- and acetylcholine-activated receptor channels translated by exogenous mRNA in Xenopus oocytes

1983 • 47 citations

The biology of the frog

1906 • 45 citations

Maturation of Xenopus oocytes is not accompanied by electrode-detectable calcium changes

1985 • 45 citations

Propagating potassium and chloride conductances during activation and fertilization of the egg of the frog, Rana pipiens.

1985 • 45 citations

Free calcium in full grown Xenopus laevis oocyte following treatment with ionophore A 23187 or progesterone

1977 • 44 citations

Adenosine-induced K+ current in Xenopus oocyte and the role of adenosine 3',5'-monophosphate.

1985 • 43 citations

Changes in membrane hydrogen and sodium conductances during progesterone-induced maturation of Ambystoma oocytes

1984 • 43 citations

Fertilization and activation potentials in Discoglossus pictus (Anura) eggs: A delayed response to activation by pricking

1985 • 43 citations

The role of Ca2+ and cyclic nucleotides in progesterone initiation of the meiotic divisions in amphibian oocytes

1981 • 42 citations

STEROID INHIBITION OF PROTEIN INCORPORATION BY ISOLATED AMPHIBIAN OOCYTES

1974 • 41 citations

Early Events in Anuran Amphibian Fertilization: An Ultrastructural Study of Changes Occurring in the Course of Monospermic Fertilization and Artificial Activation

1983 • 40 citations

Acetylcholine‐ and inositol 1,4,5‐trisphosphate‐induced calcium mobilization in Xenopus laevis oocytes

1986 • 40 citations

Calcium and Phospholipid Turnover as Transmembrane Signaling for Protein Phosphorylation

1982 • 40 citations

Maturation of Xenopus oocytes

1976 • 40 citations

Pertussis toxin inhibition of chemotaxis and the ADP-ribosylation of a membrane protein in a human-mouse hybrid cell line.

1985 • 39 citations

The effective membrane capacity ofXenopus eggs: its relations with membrane conductance and cortical granule exocytosis

1985 • 39 citations

ATP-evoked membrane responses inXenopus oocytes

1986 • 37 citations

The fate of foreign proteins introduced into Xenopus Oocytes

1981 • 37 citations

Separate fractions of mRNA from Torpedo electric organ induce chloride channels and acetylcholine receptors in Xenopus oocytes.

1984 • 37 citations

β-Adrenergic induced K ⁺ current in Xenopus oocytes: role of cAMP, inhibition by muscarinic agents

1985 • 36 citations

Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.

1986 • 36 citations

A role for action potentials in maturing Rana pipiens oocytes

1983 • 36 citations

The lonic permeability of the Amphibian oocyte in the presence or absence of external calcium

1973 • 35 citations

Induction of germinal vesicle breakdown in Xenopus laevis oocytes: Response of denuded oocytes to progesterone and insulin

1983 • 35 citations

GABA and Glycine: Postsynaptic Actions

1985 • 34 citations

The involvement of a calmodulin‐dependent phosphodiesterase in the negative control of carbamylcholine on cyclic AMP levels in dog thyroid slices

1983 • 34 citations

Forskolin potentiation of cholera toxin-stimulated cyclic AMP accumulation in intact C6-2B cells. Evidence for enhanced Gs-C coupling.

1985 • 34 citations

Differential blockade of ATP, noradrenaline and electrically evoked contractions of the rat vas deferens by nifedipine

1981 • 33 citations

Calcium Dependence of Steroid and Guanine 3′,5′- Monophosphate Induction of Germinal Vesicle Breakdown in Rana pipiens Oocytes*

1980 • 33 citations

Na+ and K+ uptake and exchange by the amphibian oocyte during the first meiotic division

1980 • 33 citations

Cyclic GMP mimics the muscarinic response in Xenopus oocytes: identity of ionic mechanisms.

1982 • 32 citations

Pertussis toxin facilitates the progesterone‐induced maturation of Xenopus oocyte

1985 • 31 citations

Sodium exchange in the cytoplasm and nucleus of amphibian oocytes

1974 • 30 citations

The membrane potential changes of amphibian eggs during species- and cross-fertilization

1985 • 29 citations

Induction of muscarinic cholinergic responsiveness inXenopus oocytes by mRNA isolated from rat brain

1985 • 28 citations

Localization of a pigment-containing structure near the surface of Xenopus eggs which contracts in response to calcium

1983 • 28 citations

Growing Xenopus oocytes have spare translational capacity.

1985 • 27 citations

The recruitment of membrane-bound mRNAs for translation in microinjected Xenopus oocytes.

1983 • 27 citations

On the role of calcium in the electrical responses of cockroach salivary gland cells to dopamine.

1980 • 27 citations

THE INJECTION OF RNA INTO LIVING CELLS: THE USE OF FROG OOCYTES FOR THE ASSAY OF mRNA AND THE STUDY OF THE CONTROL OF GENE EXPRESSION

1975 • 26 citations

Messenger RNA from rat brain induces noradrenaline and dopamine receptors in Xenopus oocytes

1984 • 26 citations

A hyperpolarization-activated chloride current in xenopus laevis oocytes under voltage-clamp

1983 • 25 citations

Slowly inactivating potassium channels induced in Xenopus oocytes by messenger ribonucleic acid from Torpedo brain.

1984 • 25 citations

GABA and Glycine: Ion Channel Mechanisms

1985 • 24 citations

Phosphoproteins associated with the regulation of a specific potassium channel in the identified Aplysia neuron R15.

1985 • 24 citations

Mechanism of action of noradrenaline on the sodium‐potassium pump in isolated rat liver cells.

1983 • 24 citations

Messenger RNA from bovine retina induces kainate and glycine receptors in Xenopus oocytes

1985 • 24 citations

An analysis of transport, exchange, and binding of sodium and potassium in isolated amphibian follicles and denuded oocytes

1977 • 23 citations

Differential Emergence of Cortical Granule Breakdown and Electrophysiological Responses during Meiotic Maturation of Toad Oocytes. (activation potential/cortical granule breakdown/ionophore A23187/oocyte maturation)

1982 • 23 citations

A voltage-dependent K+ channel controlling the membrane potential in frog oocytes

1985 • 22 citations

Characterization of the soluble cyclic nucleotide phosphodiesterases in xenopus laevis oocytes

1982 • 21 citations

Purine receptors: classification and properties

1984 • 21 citations

Regulation of Ca2+ and cyclic AMP during the first meiotic division in amphibian oocytes by progesterone.

1980 • 20 citations

Further characterization of the slow muscarinic responses inXenopus oocytes

1987 • 20 citations

Post-synthetic fate of the translation products of messenger RNA microinjected into xenopus oocytes

1979 • 19 citations

Intracellular sodium and potassium concentrations in toad and frog oocytes during development

1974 • 18 citations

Developmental change of a depolarization-induced sodium permeability in the oocyte of Xenopus laevis

1983 • 18 citations

Calmodulin modulates the cyclic AMP level in Xenopus oocyte

1983 • 17 citations

Calcium mobilization in enzymically isolated single intact and skinned muscle cells of the porcine coronary artery.

1985 • 17 citations

Return to normal of Fucus egg membrane after microelectrode impalement

1974 • 16 citations

Potassium exchange in the whole cell, cytoplasm, and nucleus of amphibian oocytes

1980 • 16 citations

cAMP-dependent protein kinase regulates in ovo camp level of the Xenopus oocyte: Evidence for an intracellular feedback mechanism

1983 • 16 citations

External Na+ inhibits Ca2+-ionophore activation of Xenopus eggs

1985 • 16 citations

Adenylate cyclase and cyclic amp‐phosphodiesterase activities during the early phase of maturation Xenopus laevis oocytes

1981 • 14 citations

Trifluoperazine‐induced meiotic maturation in Xenopus laevis

1982 • 14 citations

Investigation of possible cholinergic mechanisms in fertilization ofXenopuseggs

1981 • 14 citations

Electrophysiology of in vitro insulin‐ and progesterone‐induced reinitiation of oocyte meiosis in Rana pipiens

1984 • 13 citations

Sodium conductance and the activation potential inXenopus laevis eggs

1985 • 13 citations

Effect of the Inhibition of RNA Synthesis on in vitro Ovulation by Frog Ovaries

1969 • 12 citations

Action potentials dependent on monovalent cations in developing mouse embryos

1985 • 11 citations

Pharmacological characterization of serotonin receptor induced by rat brain messenger RNA in Xenopus oocytes

1986 • 11 citations

Dissociation of acetylcholine- and cyclic GMP-induced currents inXenopu oocytes

1987 • 11 citations

Biochemical correlates of progesterone-induced plasma membrane depolarization during the first meiotic division inRana oocytes

1984 • 10 citations

The effect of trifluoperazine on maturation of Xenopus laevis oocytes

1984 • 8 citations

Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation

1974 • 8 citations

Divalent cations and transmitter release at low concentration of tetrodotoxin

1981 • 7 citations

Cholinergic modulation of progesterone‐induced maturation of Xenopus oocytes in vitro

1985 • 5 citations

Genetic and Functional Studies of Guanine Nucleotide-Binding Regulatory Proteins

1984 • 2 citations