Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters†

Handbook of Psychopharmacology

1988 • 2,778 citations

Effect of Chlorpromazine or Haloperidol on Formation of 3‐Methoxytyramine and Normetanephrine in Mouse Brain

1963 • 2,148 citations

Advances in Cyclic Nucleotide Research.

1980 • 1,465 citations

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

Dopaminergic neurons: effect of antipsychotic drugs and amphetamine on single cell activity.

1973 • 1,272 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

Evidence for dopamine receptor stimulation by apomorphine

1967 • 910 citations

Drugs, Neurotransmitters, and Schizophrenia

1974 • 832 citations

CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASES, IV. WIDESPREAD OCCURRENCE OF ADENOSINE 3′,5′-MONOPHOSPHATE-DEPENDENT PROTEIN KINASE IN VARIOUS TISSUES AND PHYLA OF THE ANIMAL KINGDOM

1969 • 775 citations

An Anatomy of Schizophrenia?

1973 • 721 citations

The formation of synaptic junctions in developing rat brain: A quantitative electron microscopic study

1967 • 665 citations

Cyclic AMP-dependent endogenous phosphorylation of a microtubule-associated protein.

1975 • 551 citations

Cyclic Nucleotide-dependent Protein Kinases

1969 • 551 citations

Morphine receptors as regulators of adenylate cyclase activity.

1975 • 529 citations

Dopamine Receptors in the Brain

1975 • 528 citations

Frontiers in Catecholamine Research

1976 • 451 citations

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

1974 • 450 citations

Phosphorylation of a 22,000-dalton component of the cardiac sarcoplasmic reticulum by adenosine 3':5'-monophosphate-dependent protein kinase.

1975 • 431 citations

Origin and blockade of the synaptic responses of curarized sympathetic ganglia

1961 • 427 citations

Dopamine-Sensitive Adenyl Cyclase: Possible Role in Synaptic Transmission

1971 • 415 citations

Histone Phosphorylation: Stimulation by Adenosine 3′,5′-Monophosphate

1968 • 402 citations

The Stimulation of Calcium Transport in Cardiac Sarcoplasmic Reticulum by Adenosine 3′:5′-Monophosphate-dependent Protein Kinase

1974 • 398 citations

Morphine-like drugs inhibit the stimulation by E prostaglandins of cyclic AMP formation by rat brain homogenate

1974 • 373 citations

Activation of the pathway from locus coeruleus to rat cerebellar Purkinje neurons: pharmacological evidence of noradrenergic central inhibition.

1973 • 370 citations

The role of adenosine 3′,5′-phosphate in the action of antidiuretic hormone

1967 • 349 citations

Regulation of Endogenous Phosphorylation of Specific Proteins in Synaptic Membrane Fractions from Rat Brain by Adenosine 3′:5′-Monophosphate

1973 • 341 citations

Subcellular Distribution of Adenyl Cyclase and Cyclic Phosphodiesterase in Rat Brain Cortex

1967 • 337 citations

Cyclic Nucleotide-dependent Protein Kinases

1970 • 334 citations

Direct chemical stimulation of dopaminergic mechanisms in the neostriatum of the rat

1969 • 331 citations

Role of Muscarinic Cholinergic Receptors in Regulation of Guanosine 3′:5′-Cyclic Monophosphate Content in Mammalian Brain, Heart Muscle, and Intestinal Smooth Muscle

1972 • 327 citations

Role of Cyclic Amp in Cell Function

1970 • 317 citations

Stimulation by Dopamine of Adenylate Cyclase in Retinal Homogenates and of Adenosine-3′:5′-Cyclic Monophosphate Formation in Intact Retina

1972 • 286 citations

Cyclic Nucleotide-dependent Protein Kinases

1972 • 282 citations

Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. III. Evidence for mediation of norepinephrine effects by cyclic 3′, 5′-adenosine monophosphate

1971 • 257 citations

Adenosine 3′,5′-Monophosphate: Electrophysiological Evidence for a Role in Synaptic Transmission

1972 • 243 citations

Dopamine turnover in the corpus striatum and the limbic system after treatment with neuroleptic and anti-acetylcholine drugs

1972 • 235 citations

Cyclic Adenosine Monophosphate and Norepinephrine: Effects on Transmembrane Properties of Cerebellar Purkinje Cells

1971 • 230 citations

The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum

1970 • 224 citations

Octopamine-Sensitive Adenylate Cyclase: Evidence for a Biological Role of Octopamine in Nervous Tissue

1973 • 218 citations

Cyclic AMP and Cyclic GMP May Mediate Opposite Neuronal Responses in the Rat Cerebral Cortex

1975 • 216 citations

Subcellular Distribution of Adenosine 3',5'-Monophosphate-dependent Protein Kinase in Rat Brain

1971 • 208 citations

Cyclic Adenosine 3′:5′-Monophosphate-Stimulated Phosphorylation of Isolated Neurotubule Subunits

1970 • 206 citations

Adenosine 3′,5′-Monophosphate in Nervous Tissue: Increase Associated with Synaptic Transmission

1971 • 205 citations

Progress in Neurobiology

1974 • 200 citations

CHARACTERIZATION OF A DOPAMINE‐SENSITIVE ADENYLATE CYCLASE IN THE RAT CAUDATE NUCLEUS

1975 • 199 citations

Phosphorylation of Endogenous Protein of Rat Brain by Cyclic Adenosine 3′,5′-Monophosphate-dependent Protein Kinase

1971 • 192 citations

ATP, cyclic AMP, and magnesium increase the affinity of rat striatal tyrosine hydroxylase for its cofactor.

1975 • 184 citations

Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase.

1975 • 179 citations

Cyclic Nucleotide-dependent Protein Kinases

1971 • 171 citations

Effect of chlorpromazine on accumulation and disappearance of catecholamines formed from tyrosine-C14 in brain.

1968 • 171 citations

Phosphoprotein Phosphatases from Rat Cerebral Cortex

1972 • 169 citations

Regulation of catecholamine synthesis in the rat brain in vitro by cyclic AMP

1974 • 161 citations

Cyclic 3′,5′-Nucleotide Phosphodiesterase: Cytochemical Localization in Cerebral Cortex

1971 • 159 citations

Adenosine 3', 5'-Monophosphate-Dependent Membrane Phosphorylation

1974 • 156 citations

Evidence for a new type of dopamine receptor stimulating agent

1971 • 152 citations

Effects of dopamine-like drugs on rat striatal adenyl cyclase have implications for CNS dopamine receptor topography

1974 • 151 citations

Handbook of Psychopharmacology

1977 • 137 citations

Regulation of Tyrosine Hydroxylase Activity in Cultured Mouse Neuroblastoma Cells: Elevation Induced by Analogs of Adenosine 3′:5′-Cyclic Monophosphate

1972 • 136 citations

Guanosine 3′:5′-Cyclic Monophosphate-Dependent Phosphorylation of Endogenous Substrate Proteins in Membranes of Mammalian Smooth Muscle

1974 • 134 citations

Regulation of Phosphorylation of a Specific Protein in Toad-Bladder Membrane by Antidiuretic Hormone and Cyclic AMP, and Its Possible Relationship to Membrane Permeability Changes

1973 • 125 citations

Neurotransmitters Increase Cyclic Nucleotides in Postganglionic Neurons: Immunocytochemical Demonstration

1975 • 119 citations

A New Enzymatic Assay for Guanosine 3′:5′-Cyclic Monophosphate and Its Application to the Ductus Deferens of the Rat

1973 • 114 citations

Regulation of Protein Phosphorylation and Membrane Permeability by b-Adrenergic Agents and Cyclic Adenosine 3':5'-Monophosphate in the Avian Erythrocyte

1974 • 109 citations

Muscarinic cholinergic regulation of cyclic guanosine 3,5-monophosphate in autonomic ganglia: possible role in synaptic transmission.

1975 • 107 citations

Antipsychotic Drugs and Dopamine-Stimulated Adenylate Cyclase Prepared from Corpus Striatum of Rat Brain

1974 • 102 citations

Guanosine 3′,5′-Monophosphate in Sympathetic Ganglia: Increase Associated with Synaptic Transmission

1974 • 100 citations

A protein kinase activity from rat cerebellum stimulated by guanosine-3′:5′-monophosphate

1972 • 100 citations

Stimulation of Tyrosine Hydroxylase Activity in an Adrenergic Clone of Mouse Neuroblastoma by Dibutyryl Cyclic AMP

1973 • 99 citations

Reviews of neuroscience

1976 • 98 citations

Guanosine 3':5'-monophosphate-dependent protein kinase from bovine cerebellum. Purification and characterization.

1975 • 98 citations

Serotonin-Sensitive Adenylate Cyclase in Neural Tissue and Its Similarity to the Serotonin Receptor: A Possible Site of Action of Lysergic Acid Diethylamide

1974 • 96 citations

LSD as an agonist and antagonist at central dopamine receptors

1974 • 93 citations

Effect of apomorphine and pimozide on synthesis and turnover of labelled catecholamines in mouse brain

1970 • 93 citations

Evidence for the lack of direct phosphorylation of bovine caudate tyrosine hydroxylase following activation by exposure to enzymatic phosphorylating conditions

1975 • 93 citations

Cyclic 3′,5′-Nucleotide Phosphodiesterase: Localization and Latent Activity in Rat Brain

1967 • 91 citations

Beta-adrenergic stimulation of pineal N-acetyltransferase: adenosine 3':5'-cyclic monophosphate stimulates both RNA and protein synthesis.

1975 • 89 citations

The Effect of Norepinephrine and Dibutyryl Cyclic Adenosine Monophosphate on Cation Transport in Duck Erythrocytes

1971 • 88 citations

Effect of β-Adrenergic Catecholamines on Sodium Transport in Turkey Erythrocytes

1973 • 86 citations

The Reponse of Duck Erythrocytes to Norepinephrine and an Elevated Extracellular Potassium

1973 • 84 citations

The effect of trivastal, haloperidol and dibutyryl cyclic AMP on [14C]dopamine synthesis in rat striatum

1973 • 81 citations

Pharmacological analysis of synaptically mediated increase in cyclic adenosine monophosphate in rabbit superior cervical ganglion.

1974 • 76 citations

Responses of isolated curarized sympathetic ganglia

1952 • 73 citations

Interactions between lysergic acid diethylamide and dopamine-sensitive adenylate cyclase systems in rat brain

1975 • 71 citations

Regulation of protein phosphorylation and sodium transport in toad bladder.

1975 • 64 citations

Partial purification and properties of guanosine 3':5'-monophosphate-dependent protein kinase from pig lung.

1975 • 64 citations

Aldosterone-Induced Increase in Protein Phosphatase Activity of Toad Bladder

1974 • 60 citations

Measurements of adenosine 3′:5′‐cyclic monophosphate and membrane potential in neuroblastoma X glioma hybrid cells: Opiates and adrenergic agonists cause effects opposite to those of postaglandin E₁

1975 • 60 citations

Changes in relative levels of guanosine-3':5'-monophosphate-dependent and adenosine-3':5'-monophosphate-dependent protein kinases in lung, heart, and brain of developing guinea pigs.

1975 • 52 citations

Do cyclic nucleotides promote the trans-synaptic induction of tyrosine hydroxylase?

1974 • 49 citations

A dopamine-sensitive adenylate cyclase in anterior limbic cortex and mesolimbic region of primate brain

1975 • 47 citations

Solubilization of a phosphoprotein and its associated cyclic AMP-dependent protein kinase and phosphoprotein phosphatase from synaptic membrane fractions, and some kinetic evidence for their existence as a complex

1975 • 42 citations

Effect of chlorpromazine and some of its metabolites on synthesis and turnover of catecholamines formed from 14C-tyrosine in mouse brain

1972 • 40 citations

STUDIES ON THE FORMATION AND METABOLISM OF CYCLIC AMP IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM*

1971 • 24 citations

Muscarinic and nicotinic stimulant actions at autonomic ganglia

1966 • 20 citations

Advances in Cyclic Nucleotide Research

1986 • 15 citations

DOPAMINE-, OCTOPAMINE-, AND SEROTONIN-SENSITIVE ADENYLATE CYCLASES: POSSIBLE RECEPTORS IN AMINERGIC NEUROTRANSMISSION

1973 • 14 citations

Muscarinic and nicotinic stimulant actions at autonomic ganglia

1967 • 11 citations