GTP-binding proteins couple cardiac muscarinic receptors to a K channel

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Acetylcholine activation of single muscarinic K+ channels in isolated pacemaker cells of the mammalian heart

1983 • 471 citations

Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells

1984 • 436 citations

The surprising heart: a review of recent progress in cardiac electrophysiology.

1984 • 429 citations

Modification by islet-activating protein of receptor-mediated regulation of cyclic AMP accumulation in isolated rat heart cells.

1981 • 326 citations

Reconstitution of resolved muscarinic cholinergic receptors with purified GTP-binding proteins.

1985 • 314 citations

Pertussis toxin. Affinity purification of a new ADP-ribosyltransferase.

1983 • 268 citations

Changes in membrane currents in bullfrog atrium produced by acetylcholine.

1976 • 259 citations

Über humorale Übertragbarkeit der Herznervenwirkung

1926 • 253 citations

Zum Mechanismus der Membranwirkung des Acetylcholin an der Herzmuskelfaser

1958 • 247 citations

Relaxation of the ACh-induced potassium current in the rabbit sinoatrial node cell

1978 • 200 citations

The effect of intracellular cyclic nucleotides and calcium on the action potential and acetylcholine response of isolated cardiac cells

1982 • 164 citations

Time course of the increase in the myocardial slow inward current after a photochemically generated concentration jump of intracellular cAMP.

1983 • 132 citations

Na and Ca channels in a transformed line of anterior pituitary cells.

1984 • 116 citations

Synaptic delay in the heart: an ionophoretic study.

1978 • 105 citations

Ontogenesis of physiological responsiveness and guanine nucleotide sensitivity of cardiac muscarinic receptors during chick embryonic development

1984 • 79 citations

A photoisomerizable muscarinic antagonist. Studies of binding and of conductance relaxations in frog heart.

1982 • 65 citations

The time course of the muscarinic response to ionophoretic acetylcholine application to the S-A node of the rabbit heart

1981 • 56 citations

Binding of Agonists and Antagonists to Muscarinic Acetylcholine Receptors on Intact Cultured Heart Cells

1983 • 52 citations

Acetylcholine-Induced K+ Current in Amphibian Atrial Cells

1984 • 34 citations