Single-channel properties of the reconstituted voltage-regulated Na channel isolated from the electroplax of Electrophorus electricus.

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

Regulation of the Voltage Gated K<sup>+</sup> Channel K<sub>v1.3</sub> by Recombinant Human Klotho Protein

2014 • 5,592 citations

Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range

1972 • 2,632 citations

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

1952 • 2,384 citations

A simple procedure for removal of triton X-100 from protein samples

1973 • 857 citations

The Permeability of the Sodium Channel to Organic Cations in Myelinated Nerve

1971 • 751 citations

Calcium Channels in Excitable Cell Membranes

1983 • 725 citations

A reinterpretation of mammalian sodium channel gating based on single channel recording

1983 • 675 citations

Conduction and selectivity in potassium channels

1983 • 665 citations

Sodium channels and gating currents.

1981 • 541 citations

Single Na+ channel currents observed in cultured rat muscle cells

1980 • 452 citations

The Molecular Basis of Neuronal Excitability

1984 • 346 citations

Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.

1978 • 270 citations

Principal glycopeptide of the tetrodotoxin/saxitoxin binding protein from Electrophorus electricus: isolation and partial chemical and physical characterization

1983 • 264 citations

Activation of the action potential Na+ ionophore by neurotoxins. An allosteric model

1977 • 256 citations

Purification of the saxitoxin receptor of the sodium channel from rat brain.

1981 • 223 citations

Single sodium channels from rat brain incorporated into planar lipid bilayer membranes

1983 • 186 citations

Statistical analysis of single sodium channels. Effects of N-bromoacetamide

1984 • 165 citations

The saxitoxin receptor of the sodium channel from rat brain. Evidence for two nonidentical beta subunits.

1982 • 163 citations

Protein Components of the Purified Sodium Channel from Rat Skeletal Muscle Sarcolemma

1983 • 156 citations

Voltage-dependent calcium block of normal and tetramethrin-modified single sodium channels

1984 • 155 citations

Sodium channels need not open before they inactivate

1981 • 141 citations

Modification of single Na+ channels by batrachotoxin.

1982 • 137 citations

Purification from rat sarcolemma of the saxitoxin-binding component of the excitable membrane sodium channel.

1980 • 129 citations

The sodium channel from rat brain. Reconstitution of neurotoxin-activated ion flux and scorpion toxin binding from purified components.

1984 • 122 citations

Ion flux studies of voltage-sensitive sodium channels in synaptic nerve-ending particles.

1981 • 120 citations

Voltage-Regulated Sodium Channel Molecules

1984 • 117 citations

Isolated-patch recording from liposomes containing functionally reconstituted chloride channels from Torpedo electroplax.

1982 • 97 citations

Functional reconstitution of the purified sodium channel protein from rat sarcolemma.

1982 • 96 citations

Reconstitution of neurotoxin-stimulated sodium transport by the voltage-sensitive sodium channel purified from rat brain.

1982 • 94 citations

Reconstitution of neurotoxin-modulated ion transport by the voltage-regulated sodium channel isolated from the electroplax of Electrophorus electricus.

1984 • 87 citations

Voltage-dependent block by saxitoxin of sodium channels incorporated into planar lipid bilayers

1984 • 86 citations

Sodium channel selectivity. Dependence on internal permeant ion concentration.

1976 • 77 citations

Cation selectivity characteristics of the reconstituted voltage-dependent sodium channel purified from rat skeletal muscle sarcolemma.

1983 • 73 citations

Gating kinetics of batrachotoxin-modified sodium channels in neuroblastoma cells determined from single-channel measurements

1984 • 67 citations

The effect of tetramethylammonium on single sodium channel currents

1981 • 62 citations