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Inhibition of RhoA by p120 catenin

Data up to Jan 2025

Published2000
Citations459
References39

Total Citations Per Year

Abstract

References (39)

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1991 • 1,686 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.

1991 • 1,592 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Morphogenetic roles of classic cadherins

1995 • 1,468 citations

A causal role for E-cadherin in the transition from adenoma to carcinoma

1998 • 1,415 citations

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

1997 • 772 citations

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway.

1996 • 601 citations

Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells

1997 • 555 citations

Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.

1994 • 490 citations

Rho Guanine Dissociation Inhibitors

1999 • 487 citations

Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion

2000 • 456 citations

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.

1996 • 452 citations

The p120 catenin family: Complex roles in adhesion, signaling and cancer

2000 • 427 citations

Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members.

1994 • 347 citations

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia.

1995 • 304 citations

Rho- and Rac-dependent Assembly of Focal Adhesion Complexes and Actin Filaments in Permeabilized Fibroblasts: An Essential Role for Ezrin/Radixin/Moesin Proteins

1997 • 303 citations

Activation of RhoA by Lysophosphatidic Acid and Gα12/13Subunits in Neuronal Cells: Induction of Neurite Retraction

1999 • 303 citations

Effects of Regulated Expression of Mutant RhoA and Rac1 Small GTPases on the Development of Epithelial (MDCK) Cell Polarity

1998 • 297 citations

Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells

1997 • 285 citations

cAMP-induced Morphological Changes Are Counteracted by the Activated RhoA Small GTPase and the Rho Kinase ROKα

1998 • 267 citations

Tyrosine Phosphorylation and Src Family Kinases Control Keratinocyte Cell–Cell Adhesion

1998 • 254 citations

p120ctn Acts as an Inhibitory Regulator of Cadherin Function in Colon Carcinoma Cells

1999 • 229 citations

Regulation of cadherin-mediated cell–cell adhesion by the Rho family GTPases

1999 • 204 citations

The Rho Small G Protein Family-Rho GDI System as a Temporal and Spatial Determinant for Cytoskeletal Control

1998 • 200 citations

The Membrane-proximal Region of the E-Cadherin Cytoplasmic Domain Prevents Dimerization and Negatively Regulates Adhesion Activity

1998 • 173 citations

Molecular Cloning of the Human p120ctnCatenin Gene (CTNND1): Expression of Multiple Alternatively Spliced Isoforms

1998 • 168 citations

The Novel Catenin p120casBinds Classical Cadherins and Induces an Unusual Morphological Phenotype in NIH3T3 Fibroblasts

1996 • 153 citations

Regulation of Astrocyte Morphology by RhoA and Lysophosphatidic Acid

1998 • 153 citations

The Morphogenetic Role of Cadherin Cell Adhesion Molecules in Human Cancer: A Thematic Review

1998 • 141 citations

Signaling mechanisms and molecular characteristics of G protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate

1998 • 132 citations

Morphological Changes and Detachment of Adherent Cells Induced by p122, a GTPase-activating Protein for Rho

1999 • 101 citations

ARVCF localizes to the nucleus and adherens junction and is mutually exclusive with P120ctn in E-cadherin complexes

2000 • 85 citations

Rho regulates association of both the ERM family and vinculin with the plasma membrane in MDCK cells

1997 • 75 citations

Structural Determinants Required for the Interaction between Rho GTPase and the GTPase-activating Domain of p190

1997 • 68 citations

Residues of the Rho Family GTPases Rho and Cdc42 That Specify Sensitivity to Dbl-like Guanine Nucleotide Exchange Factors

1997 • 68 citations

A Built-in Arginine Finger Triggers the Self-stimulatory GTPase-activating Activity of Rho Family GTPases

1999 • 52 citations

Production and Characterization of Monoclonal Antibodies to the Catenin pl20ctn

1998 • 50 citations

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Inhibition of RhoA by p120 catenin (2000) – Nature Cell Biology | Metascience Observatory Explorer